Basic Information

Type: gene

Biological Identity

Species

rosa_laevigata

Chromosome

Chr2

Orthogroup ID

OG0005020

Physical Location & Seq

Genomic Coordinates Forward (+)

44032254 .. 44035150

Gene Structure 2897 bp

Loading structure...

UTR

Exon/CDS

Intron

Transcript / Protein ID

RLM00000008968

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1329 bp

ATGGGATTTGCCAACAACATAGGCAAGTACCAGCTGGGGCGGACGATCGGAGAAGGTACTTTTGCCAAGGTGAAGCTGGCACTCGACAGCACTAATGGAAAGTATGTTGCCATCAAGATCCTCGATAAGCATATGGTCATGGAAACCAATCTCATGAATCAGGTGCAGAGAGAAATTAGAACAATGAAGCTTCTAAATCACTCCAACATTGTTATTGGTACAAAGACAAAAATCTACATAGCAATGGAATATGTATCTGGGGGACAACTCTCAGACAAATTGTTGTATTCCAAAACATTAAGTGAAAGGGAGGCAAGAAAGCTTTTTCAGCAATTGATAGATGCAGTGGACTACTGTCACAACAAAGGTGTATATCACAGAGATATAAAGCCAGAAAACTTGCTTTTGACCAGTAATGGAGACCTCAAAATATCTGATTTTGGACTTAGCGCATTGCGTAAGCCTGGTGACTTGTTGTCAACTAAATGTGGTTCTCCAAGCTATGTAGCTCCTGAGCTACTTGTAAATAAGGGCTATGATGGAGCAGCTGCAGATGTTTGGTCTTGTGGAGTGATTCTTTTCGAATTACTTGCAGGTCATCTGCCATTTGATGACTCTAGCCTGATGAATTTGTACAAAAAGATATCCAGAGCAGAATACAGATTTCCACATTGGTTTACAGAAAGCCAAAAGAAGCTGATCTCAGGAATATTTGATCCGAATCCCAAAAGGCGACTAACAATACCAGAAATTATCGAAAATCAATGGTTCCAAAAGGATTACGTACCTATATGTGGAAATGATAGTGACGAGAAAATCTACTTAGATGATGTCAATGCTGCATTTGATTCAATAGAGGAAAATGTCAAGGCGACCAAAATTCCCAAATCATCAAGTTTTATAAATGCTTTCCAATTGATAGCCATGTCAAATGATCTGGATTTATCAGGTCTTTTTGAGGAACAGAATAACAAGAAGCAGAAAATAAGGCTTGGATCCCAGCACACAATCAATGAAACCATGAAGAAAATAGAAGCTGCTGCAATGGATGTGAGTCTTTCTGTAGCAAGAACAAACAACTTTAAGGTGATCGAAGTGGCTCCCGCACATTGTGTTGTAGAAATATCAAGATCCGCAGGGGAGCTTGGACCATACAATGAATTCTGTAAGAGTCTAACAAGTCAGCTGACAGAGGAATCAGGTGATTCATCACAAATGCAAGAGTCTGAGGTACACCACAGTGAAAGCAAAAGTATTCAAGAAAGTGAAGGGTCCAAGAAGACAAAATCCACAAGAATCGACGATCACCGTGGTTATTCATCTTCTTGA

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0000325 GO:0003674 GO:0003824 GO:0004672 GO:0004674 GO:0005575 GO:0005622 GO:0005623 GO:0005634 GO:0005737 GO:0005773 GO:0005774 GO:0005829 GO:0006464 GO:0006468 GO:0006793 GO:0006796 GO:0006807 GO:0006950 GO:0006970 GO:0007154 GO:0007165 GO:0008150 GO:0008152 GO:0009628 GO:0009651 GO:0009705 GO:0009987 GO:0016020 GO:0016301 GO:0016310 GO:0016740 GO:0016772 GO:0016773 GO:0019538 GO:0023052 GO:0031090 GO:0033554 GO:0035556 GO:0036211 GO:0043170 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0043412 GO:0044237 GO:0044238 GO:0044260 GO:0044267 GO:0044422 GO:0044424 GO:0044437 GO:0044444 GO:0044446 GO:0044464 GO:0050789 GO:0050794 GO:0050896 GO:0051716 GO:0065007 GO:0071214 GO:0071470 GO:0071472 GO:0071704 GO:0098588 GO:0098805 GO:0104004 GO:0140096 GO:1901564

KEGG Pathways

Metabolic & Signaling

ko04068 ko04140 ko04150 ko04151 ko04152 ko04211 ko04213 ko04371 ko04530 ko04710 ko04714 ko04910 ko04920 ko04921 ko04922 ko04931 ko04932 ko05410 ko05418 map04068 map04140 map04150 map04151 map04152 map04211 map04213 map04371 map04530 map04710 map04714 map04910 map04920 map04921 map04922 map04931 map04932 map05410 map05418

Pfam Domains

Protein Families

NAF Pkinase

Protein Analysis

443

Amino Acids

49.51

Weight (kDa)

6.62

Isoelectric Point (pI)

38.49

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
Pkinase	PF00069	10 - 257	7.5e-69	Protein kinase domain
PK_Tyr_Ser-Thr	PF07714	11 - 253	1.4e-35	Protein tyrosine and serine/threonine kinase
Kinase-like	PF14531	99 - 206	6.3e-06	Kinase-like
NAF	PF03822	299 - 356	1.5e-16	NAF domain

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

Style Settings

Font Size (px)

Line Width

Align Labels (Cladogram)

Image

Tree File

Tip: Beautify your tree with professional tools

Download the Full Tree (.nwk) file, then upload it to any of the following tools to customize colors, fonts, annotations, clades, and branch support.

Publication-ready

iTOL Interactive Tree Of Life · Most popular EvolView Flexible annotations MEGA Desktop phylogenetics suite FigTree Desktop tree editor

Orthologous Genes (Group: OG0005020)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT5G57630 AT5G57630 AT5G57630
fragaria_vesca	FvH4_4g08900 FvH4_4g08900 FvH4_4g08900 FvH4_4g08900 FvH4_4g08900 FvH4_4g08900
malus_domestica	MD13G1265500.v1.1
prunus_persica	Prupe.1G091700_v2.0.a1 Prupe.1G091700_v2.0.a1
pyrus_communis	pycom13g23580
rosa_chinensis	RchiOBHm_Chr4g0403561
rosa_laevigata	RLG00000008968 RLG00000017445
rosa_multiflora	Rmu_sc0007038.1_g000017
rosa_roxburghii	Rroxscaffold_2G00103160 Rroxscaffold_2G00117840 Rroxscaffold_5G00348210
rosa_rugosa	Rorug04G0044300 Rorug04G0044400
rosa_samantha	Rh1CG276800 Rh2CG037600 Rh4AG119500 Rh4BG112600 Rh4CG127500 Rh4DG112200 Rh5CG124600
rosa_wichuraiana	Rw4G009700

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AanI	TTATAA	1 cut(s)	902
Acc36I	ACCTGC	1 cut(s)	584
AciI	CCGC	3 cut(s)	40, 1104, 1134
AclWI	GGATC	5 cut(s)	112, 710, 990, 1003, 1125
AcsI	RAATTY	3 cut(s)	628, 879, 1160
AdeI	CACNNNGTG	1 cut(s)	1112
AfaI	GTAC	6 cut(s)	29, 58, 220, 635, 786, 1233
AfiI	CCNNNNNNNGG	1 cut(s)	794
AgsI	TTSAA	2 cut(s)	852, 1259
AhdI	GACNNNNNGTC	1 cut(s)	475
AjnI	CCWGG	1 cut(s)	463
AleI	CACNNNNGTG	1 cut(s)	1239
Alw26I	GTCTC	1 cut(s)	414
AlwI	GGATC	5 cut(s)	112, 710, 990, 1003, 1125
ApeKI	GCWGC	5 cut(s)	545, 548, 839, 1037, 1040
ApoI	RAATTY	3 cut(s)	628, 879, 1160
AspLEI	GCGC	1 cut(s)	452
AspS9I	GGNCC	2 cut(s)	1148, 1272
AsuHPI	GGTGA	5 cut(s)	82, 479, 1099, 1214, 1298
AsuII	TTCGAA	1 cut(s)	582
AvaII	GGWCC	2 cut(s)	1148, 1272
BamHI	GGATCC	1 cut(s)	995
BbsI	GAAGAC	1 cut(s)	1286
BbvI	GCAGC	5 cut(s)	535, 557, 826, 1024, 1027
BccI	CCATC	2 cut(s)	119, 533
BcgI	CGANNNNNNTGC	2 cut(s)	572, 606
BciT130I	CCWGG	1 cut(s)	465
BcoDI	GTCTC	1 cut(s)	414
BfaI	CTAG	1 cut(s)	618
BfmI	CTRYAG	2 cut(s)	549, 1062
BfuAI	ACCTGC	1 cut(s)	584
BisI	GCNGC	5 cut(s)	546, 549, 840, 1038, 1041
BlsI	GCNGC	5 cut(s)	547, 550, 841, 1039, 1042
Bme1390I	CCNGG	1 cut(s)	465
Bme18I	GGWCC	2 cut(s)	1148, 1272
BmeRI	GACNNNNNGTC	1 cut(s)	475
BmgT120I	GGNCC	2 cut(s)	1148, 1272
BmiI	GGNNCC	4 cut(s)	770, 997, 1101, 1273
BmrFI	CCNGG	1 cut(s)	465
BmsI	GCATC	1 cut(s)	331
BoxI	GACNNNNGTC	1 cut(s)	354
BpiI	GAAGAC	1 cut(s)	1286
Bpu10I	CCTNAGC	1 cut(s)	513
Bpu14I	TTCGAA	1 cut(s)	582
BsaAI	YACGTR	1 cut(s)	784
BsaBI	GATNNNNATC	1 cut(s)	720
BsaI	GGTCTC	1 cut(s)	414
BsaJI	CCNNGG	2 cut(s)	66, 1309
Bsc4I	CCNNNNNNNGG	1 cut(s)	794
Bse1I	ACTGG	1 cut(s)	411
Bse3DI	GCAATG	3 cut(s)	249, 452, 1050
Bse8I	GATNNNNATC	1 cut(s)	720
BseBI	CCWGG	1 cut(s)	465
BseDI	CCNNGG	2 cut(s)	66, 1309
BseGI	GGATG	1 cut(s)	1054
BseJI	GATNNNNATC	1 cut(s)	720
BseLI	CCNNNNNNNGG	1 cut(s)	794
BseMI	GCAATG	3 cut(s)	249, 452, 1050
BseMII	CTCAG	4 cut(s)	285, 504, 717, 1218
BseNI	ACTGG	1 cut(s)	411
BseXI	GCAGC	5 cut(s)	535, 557, 826, 1024, 1027
BseYI	CCCAGC	2 cut(s)	34, 999
BsgI	GTGCAG	1 cut(s)	185
Bsh1285I	CGRYCG	1 cut(s)	48
BsiEI	CGRYCG	1 cut(s)	48
BslFI	GGGAC	1 cut(s)	276
BslI	CCNNNNNNNGG	1 cut(s)	794
BsmAI	GTCTC	1 cut(s)	414
BsmFI	GGGAC	1 cut(s)	276
Bso31I	GGTCTC	1 cut(s)	414
Bsp119I	TTCGAA	1 cut(s)	582
Bsp1407I	TGTACA	1 cut(s)	633
Bsp143I	GATC	9 cut(s)	45, 117, 699, 715, 934, 995, 1089, 1130, 1303
BspACI	CCGC	3 cut(s)	40, 1104, 1134
BspCNI	CTCAG	4 cut(s)	284, 505, 716, 1219
BspHI	TCATGA	1 cut(s)	153
BspLI	GGNNCC	4 cut(s)	770, 997, 1101, 1273
BspMAI	CTGCAG	1 cut(s)	553
BspMI	ACCTGC	1 cut(s)	584
BspPI	GGATC	5 cut(s)	112, 710, 990, 1003, 1125
BspT104I	TTCGAA	1 cut(s)	582
BspTNI	GGTCTC	1 cut(s)	414
BsrDI	GCAATG	3 cut(s)	249, 452, 1050
BsrGI	TGTACA	1 cut(s)	633
BsrI	ACTGG	1 cut(s)	411
BssECI	CCNNGG	2 cut(s)	66, 1309
BssMI	GATC	9 cut(s)	45, 117, 699, 715, 934, 995, 1089, 1130, 1303
BssT1I	CCWWGG	1 cut(s)	66
Bst2UI	CCWGG	1 cut(s)	465
Bst4CI	ACNGT	3 cut(s)	356, 1241, 1310
BstAUI	TGTACA	1 cut(s)	633
BstBAI	YACGTR	1 cut(s)	784
BstBI	TTCGAA	1 cut(s)	582
BstC8I	GCNNGC	1 cut(s)	78
BstDEI	CTNAG	6 cut(s)	271, 446, 513, 703, 823, 1227
BstDSI	CCRYGG	1 cut(s)	1309
BstF5I	GGATG	1 cut(s)	1054
BstHHI	GCGC	1 cut(s)	452
BstKTI	GATC	9 cut(s)	48, 120, 702, 718, 937, 998, 1092, 1133, 1306
BstMAI	GTCTC	1 cut(s)	414
BstMBI	GATC	9 cut(s)	45, 117, 699, 715, 934, 995, 1089, 1130, 1303
BstMCI	CGRYCG	1 cut(s)	48
BstMWI	GCNNNNNNNGC	1 cut(s)	328
BstNI	CCWGG	1 cut(s)	465
BstPAI	GACNNNNGTC	1 cut(s)	354
BstSCI	CCNGG	1 cut(s)	463
BstSFI	CTRYAG	2 cut(s)	549, 1062
BstSNI	TACGTA	1 cut(s)	784
BstV1I	GCAGC	5 cut(s)	535, 557, 826, 1024, 1027
BstV2I	GAAGAC	1 cut(s)	1286
BstX2I	RGATCY	3 cut(s)	117, 995, 1130
BstYI	RGATCY	3 cut(s)	117, 995, 1130
BtgI	CCRYGG	1 cut(s)	1309
BtsCI	GGATG	1 cut(s)	1054
BtsI	GCAGTG	1 cut(s)	351
BtsIMutI	CAGTG	2 cut(s)	351, 1246
BveI	ACCTGC	1 cut(s)	584
Cac8I	GCNNGC	1 cut(s)	78
CciI	TCATGA	1 cut(s)	153
CfoI	GCGC	1 cut(s)	452
Cfr13I	GGNCC	2 cut(s)	1148, 1272
Csp6I	GTAC	6 cut(s)	28, 57, 219, 634, 785, 1232
CviAII	CATG	4 cut(s)	139, 154, 925, 1021
CviQI	GTAC	6 cut(s)	28, 57, 219, 634, 785, 1232
DdeI	CTNAG	6 cut(s)	271, 446, 513, 703, 823, 1227
DpnI	GATC	9 cut(s)	47, 119, 701, 717, 936, 997, 1091, 1132, 1305
DpnII	GATC	9 cut(s)	45, 117, 699, 715, 934, 995, 1089, 1130, 1303
DraIII	CACNNNGTG	1 cut(s)	1112
DriI	GACNNNNNGTC	1 cut(s)	475
Eam1105I	GACNNNNNGTC	1 cut(s)	475
EciI	GGCGGA	1 cut(s)	55
Eco105I	TACGTA	1 cut(s)	784
Eco130I	CCWWGG	1 cut(s)	66
Eco31I	GGTCTC	1 cut(s)	414
Eco32I	GATATC	1 cut(s)	645
Eco47I	GGWCC	2 cut(s)	1148, 1272
EcoRI	GAATTC	1 cut(s)	1160
EcoRII	CCWGG	1 cut(s)	463
EcoRV	GATATC	1 cut(s)	645
EcoT14I	CCWWGG	1 cut(s)	66
ErhI	CCWWGG	1 cut(s)	66
FaeI	CATG	4 cut(s)	142, 157, 928, 1024
FaqI	GGGAC	1 cut(s)	276
FatI	CATG	4 cut(s)	138, 153, 924, 1020
FauI	CCCGC	1 cut(s)	1111
FauNDI	CATATG	1 cut(s)	132
Fnu4HI	GCNGC	5 cut(s)	546, 549, 840, 1038, 1041
FokI	GGATG	1 cut(s)	1061
Fsp4HI	GCNGC	5 cut(s)	546, 549, 840, 1038, 1041
FspBI	CTAG	1 cut(s)	618
GlaI	GCGC	1 cut(s)	451
GluI	GCNGC	5 cut(s)	546, 549, 840, 1038, 1041
GsaI	CCCAGC	2 cut(s)	38, 1003
HhaI	GCGC	1 cut(s)	452
Hin1II	CATG	4 cut(s)	142, 157, 928, 1024
Hin6I	GCGC	1 cut(s)	450
HinP1I	GCGC	1 cut(s)	450
HincII	GTYRAC	1 cut(s)	480
HindII	GTYRAC	1 cut(s)	480
HindIII	AAGCTT	2 cut(s)	188, 320
HphI	GGTGA	5 cut(s)	82, 479, 1099, 1214, 1298
Hpy166II	GTNNAC	4 cut(s)	349, 480, 678, 1234
Hpy188I	TCNGA	5 cut(s)	50, 274, 436, 720, 1228
Hpy188III	TCNNGA	9 cut(s)	115, 154, 512, 648, 705, 938, 1128, 1259, 1326
Hpy8I	GTNNAC	4 cut(s)	349, 480, 678, 1234
Hpy99I	CGWCG	1 cut(s)	1304
HpyAV	CCTTC	2 cut(s)	47, 1262
HpyCH4III	ACNGT	3 cut(s)	356, 1241, 1310
HpyCH4IV	ACGT	1 cut(s)	783
HpyCH4V	TGCA	7 cut(s)	166, 344, 551, 593, 842, 1043, 1219
HpyF10VI	GCNNNNNNNGC	1 cut(s)	328
HpyF3I	CTNAG	6 cut(s)	271, 446, 513, 703, 823, 1227
HpySE526I	ACGT	1 cut(s)	783
Hsp92II	CATG	4 cut(s)	142, 157, 928, 1024
HspAI	GCGC	1 cut(s)	450
Kzo9I	GATC	9 cut(s)	45, 117, 699, 715, 934, 995, 1089, 1130, 1303
LmnI	GCTCC	4 cut(s)	514, 542, 1105, 1141
Lsp1109I	GCAGC	5 cut(s)	535, 557, 826, 1024, 1027
LweI	GCATC	1 cut(s)	331
MaeI	CTAG	1 cut(s)	618
MaeII	ACGT	1 cut(s)	783
MaeIII	GTNAC	3 cut(s)	356, 467, 806
MalI	GATC	9 cut(s)	47, 119, 701, 717, 936, 997, 1091, 1132, 1305
MboI	GATC	9 cut(s)	45, 117, 699, 715, 934, 995, 1089, 1130, 1303
MboII	GAAGA	3 cut(s)	1036, 1291, 1314
MfeI	CAATTG	2 cut(s)	332, 914
MflI	RGATCY	3 cut(s)	117, 995, 1130
MluCI	AATT	9 cut(s)	174, 278, 332, 584, 628, 750, 879, 914, 1160
MlyI	GAGTC	4 cut(s)	608, 1063, 1180, 1232
MmeI	TCCRAC	1 cut(s)	228
MnlI	CCTC	7 cut(s)	131, 304, 434, 850, 952, 1186, 1222
MseI	TTAA	2 cut(s)	299, 1083
MslI	CAYNNNNRTG	2 cut(s)	242, 1239
MspA1I	CMGCKG	3 cut(s)	34, 548, 1186
MspR9I	CCNGG	1 cut(s)	465
MunI	CAATTG	2 cut(s)	332, 914
MvaI	CCWGG	1 cut(s)	465
MwoI	GCNNNNNNNGC	1 cut(s)	328
NdeI	CATATG	1 cut(s)	132
NdeII	GATC	9 cut(s)	45, 117, 699, 715, 934, 995, 1089, 1130, 1303
NlaIII	CATG	4 cut(s)	142, 157, 928, 1024
NlaIV	GGNNCC	4 cut(s)	770, 997, 1101, 1273
NmuCI	GTSAC	3 cut(s)	356, 467, 806
NspV	TTCGAA	1 cut(s)	582
OliI	CACNNNNGTG	1 cut(s)	1239
PagI	TCATGA	1 cut(s)	153
PfeI	GAWTC	7 cut(s)	157, 574, 721, 848, 1196, 1205, 1296
PkrI	GCNGC	5 cut(s)	547, 550, 841, 1039, 1042
Ple19I	CGATCG	1 cut(s)	48
PleI	GAGTC	4 cut(s)	608, 1062, 1179, 1231
PpsI	GAGTC	4 cut(s)	608, 1062, 1179, 1231
Ppu21I	YACGTR	1 cut(s)	784
PshAI	GACNNNNGTC	1 cut(s)	354
PsiI	TTATAA	1 cut(s)	902
Psp6I	CCWGG	1 cut(s)	463
PspFI	CCCAGC	2 cut(s)	34, 999
PspGI	CCWGG	1 cut(s)	463
PspN4I	GGNNCC	4 cut(s)	770, 997, 1101, 1273
PspPI	GGNCC	2 cut(s)	1148, 1272
PstI	CTGCAG	1 cut(s)	553
PsuI	RGATCY	3 cut(s)	117, 995, 1130
PvuI	CGATCG	1 cut(s)	48
PvuII	CAGCTG	3 cut(s)	34, 548, 1186
RsaI	GTAC	6 cut(s)	29, 58, 220, 635, 786, 1233
RsaNI	GTAC	6 cut(s)	28, 57, 219, 634, 785, 1232
RseI	CAYNNNNRTG	2 cut(s)	242, 1239
SaqAI	TTAA	2 cut(s)	299, 1083
SatI	GCNGC	5 cut(s)	546, 549, 840, 1038, 1041
Sau3AI	GATC	9 cut(s)	45, 117, 699, 715, 934, 995, 1089, 1130, 1303
Sau96I	GGNCC	2 cut(s)	1148, 1272
SchI	GAGTC	4 cut(s)	608, 1063, 1180, 1232
ScrFI	CCNGG	1 cut(s)	465
SfaNI	GCATC	1 cut(s)	331
SfcI	CTRYAG	2 cut(s)	549, 1062
SfuI	TTCGAA	1 cut(s)	582
SinI	GGWCC	2 cut(s)	1148, 1272
SmiMI	CAYNNNNRTG	2 cut(s)	242, 1239
SnaBI	TACGTA	1 cut(s)	784
Sse9I	AATT	9 cut(s)	174, 278, 332, 584, 628, 750, 879, 914, 1160
SsiI	CCGC	3 cut(s)	40, 1104, 1134
SspI	AATATT	1 cut(s)	711
SspMI	CTAG	1 cut(s)	618
StyD4I	CCNGG	1 cut(s)	463
StyI	CCWWGG	1 cut(s)	66
TaaI	ACNGT	3 cut(s)	356, 1241, 1310
TaiI	ACGT	1 cut(s)	786
TaqI	TCGA	6 cut(s)	84, 123, 582, 756, 1092, 1299
TasI	AATT	9 cut(s)	174, 278, 332, 584, 628, 750, 879, 914, 1160
TatI	WGTACW	1 cut(s)	633
TfiI	GAWTC	7 cut(s)	157, 574, 721, 848, 1196, 1205, 1296
Tru1I	TTAA	2 cut(s)	299, 1083
Tru9I	TTAA	2 cut(s)	299, 1083
TscAI	CASTG	2 cut(s)	351, 1246
TseFI	GTSAC	3 cut(s)	356, 467, 806
TseI	GCWGC	5 cut(s)	545, 548, 839, 1037, 1040
Tsp45I	GTSAC	3 cut(s)	356, 467, 806
TspDTI	ATGAA	8 cut(s)	170, 200, 641, 1029, 1037, 1173, 1197, 1308
TspRI	CASTG	2 cut(s)	351, 1246
VpaK11BI	GGWCC	2 cut(s)	1148, 1272
XapI	RAATTY	3 cut(s)	628, 879, 1160
XcmI	CCANNNNNNNNNTGG	1 cut(s)	73
XspI	CTAG	1 cut(s)	618

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.