Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
Download the Full Tree (.nwk) file, then upload it to any of the following tools to customize colors, fonts, annotations, clades, and branch support.
| Species | Orthologous Gene IDs |
|---|---|
| rosa_laevigata | RLG00000007912 |
| rosa_roxburghii | Rroxscaffold_1G00013790 Rroxscaffold_3G00218570 Rroxscaffold_3G00218580 Rroxscaffold_3G00252300 Rroxscaffold_6G00425440 Rroxscaffold_7G00199340 |
| rosa_rugosa | Rorug01G0267500 Rorug01G0267600 Rorug03G0293600 |
| rosa_samantha | Rh2BG557900 Rh4AG086500 Rh4CG083600 Rh4CG094300 Rh4DG195600 Rh5BG296200 Rh5BG488700 Rh5DG337900 Rh5DG565200 |
| rosa_wichuraiana | Rw5G048490 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AccII | CGCG | 1 cut(s) | 14 |
| AciI | CCGC | 1 cut(s) | 374 |
| AdeI | CACNNNGTG | 1 cut(s) | 183 |
| AfaI | GTAC | 1 cut(s) | 133 |
| AflIII | ACRYGT | 1 cut(s) | 12 |
| AgsI | TTSAA | 5 cut(s) | 86, 110, 143, 149, 174 |
| AhdI | GACNNNNNGTC | 1 cut(s) | 13 |
| AloI | GAACNNNNNNTCC | 2 cut(s) | 337, 369 |
| AluBI | AGCT | 2 cut(s) | 299, 484 |
| AluI | AGCT | 2 cut(s) | 299, 484 |
| Alw26I | GTCTC | 1 cut(s) | 447 |
| AoxI | GGCC | 2 cut(s) | 153, 415 |
| ApeKI | GCWGC | 3 cut(s) | 161, 299, 302 |
| Asp700I | GAANNNNTTC | 1 cut(s) | 105 |
| BanII | GRGCYC | 1 cut(s) | 23 |
| BbvI | GCAGC | 3 cut(s) | 148, 286, 289 |
| BceAI | ACGGC | 1 cut(s) | 430 |
| BcoDI | GTCTC | 1 cut(s) | 447 |
| BfaI | CTAG | 2 cut(s) | 476, 485 |
| BglII | AGATCT | 2 cut(s) | 112, 136 |
| BisI | GCNGC | 4 cut(s) | 162, 300, 303, 375 |
| BlsI | GCNGC | 4 cut(s) | 163, 301, 304, 376 |
| BmeRI | GACNNNNNGTC | 1 cut(s) | 13 |
| BmiI | GGNNCC | 1 cut(s) | 397 |
| BmrI | ACTGGG | 2 cut(s) | 189, 250 |
| BmsI | GCATC | 1 cut(s) | 232 |
| BmuI | ACTGGG | 2 cut(s) | 189, 250 |
| BplI | GAGNNNNNCTC | 2 cut(s) | 341, 373 |
| BpuEI | CTTGAG | 2 cut(s) | 34, 137 |
| Bse1I | ACTGG | 2 cut(s) | 184, 256 |
| BseNI | ACTGG | 2 cut(s) | 184, 256 |
| BseXI | GCAGC | 3 cut(s) | 148, 286, 289 |
| Bsh1236I | CGCG | 1 cut(s) | 14 |
| BshFI | GGCC | 2 cut(s) | 155, 417 |
| BsmAI | GTCTC | 1 cut(s) | 447 |
| BsnI | GGCC | 2 cut(s) | 155, 417 |
| Bsp1286I | GDGCHC | 1 cut(s) | 23 |
| Bsp1407I | TGTACA | 1 cut(s) | 131 |
| Bsp143I | GATC | 2 cut(s) | 112, 136 |
| BspACI | CCGC | 1 cut(s) | 374 |
| BspANI | GGCC | 2 cut(s) | 155, 417 |
| BspFNI | CGCG | 1 cut(s) | 14 |
| BspLI | GGNNCC | 1 cut(s) | 397 |
| BspQI | GCTCTTC | 1 cut(s) | 81 |
| BsrGI | TGTACA | 1 cut(s) | 131 |
| BsrI | ACTGG | 2 cut(s) | 184, 256 |
| BssMI | GATC | 2 cut(s) | 112, 136 |
| Bst4CI | ACNGT | 2 cut(s) | 30, 64 |
| Bst6I | CTCTTC | 1 cut(s) | 81 |
| BstAUI | TGTACA | 1 cut(s) | 131 |
| BstDEI | CTNAG | 1 cut(s) | 187 |
| BstFNI | CGCG | 1 cut(s) | 14 |
| BstKTI | GATC | 2 cut(s) | 115, 139 |
| BstMAI | GTCTC | 1 cut(s) | 447 |
| BstMBI | GATC | 2 cut(s) | 112, 136 |
| BstMWI | GCNNNNNNNGC | 4 cut(s) | 161, 167, 308, 371 |
| BstUI | CGCG | 1 cut(s) | 14 |
| BstV1I | GCAGC | 3 cut(s) | 148, 286, 289 |
| BstX2I | RGATCY | 2 cut(s) | 112, 136 |
| BstYI | RGATCY | 2 cut(s) | 112, 136 |
| BsuRI | GGCC | 2 cut(s) | 155, 417 |
| BtsI | GCAGTG | 2 cut(s) | 245, 435 |
| BtsIMutI | CAGTG | 3 cut(s) | 177, 245, 435 |
| CseI | GACGC | 1 cut(s) | 3 |
| Csp6I | GTAC | 1 cut(s) | 132 |
| CviJI | RGCY | 9 cut(s) | 21, 55, 91, 155, 170, 299, 377, 417, 484 |
| CviKI_1 | RGCY | 9 cut(s) | 21, 55, 91, 155, 170, 299, 377, 417, 484 |
| CviQI | GTAC | 1 cut(s) | 132 |
| DdeI | CTNAG | 1 cut(s) | 187 |
| DpnI | GATC | 2 cut(s) | 114, 138 |
| DpnII | GATC | 2 cut(s) | 112, 136 |
| DraIII | CACNNNGTG | 1 cut(s) | 183 |
| DriI | GACNNNNNGTC | 1 cut(s) | 13 |
| Eam1104I | CTCTTC | 1 cut(s) | 81 |
| Eam1105I | GACNNNNNGTC | 1 cut(s) | 13 |
| EarI | CTCTTC | 1 cut(s) | 81 |
| Eco24I | GRGCYC | 1 cut(s) | 23 |
| EcoT38I | GRGCYC | 1 cut(s) | 23 |
| FaiI | YATR | 1 cut(s) | 58 |
| Fnu4HI | GCNGC | 4 cut(s) | 162, 300, 303, 375 |
| FriOI | GRGCYC | 1 cut(s) | 23 |
| Fsp4HI | GCNGC | 4 cut(s) | 162, 300, 303, 375 |
| FspBI | CTAG | 2 cut(s) | 476, 485 |
| GluI | GCNGC | 4 cut(s) | 162, 300, 303, 375 |
| HaeIII | GGCC | 2 cut(s) | 155, 417 |
| HgaI | GACGC | 1 cut(s) | 3 |
| HinfI | GANTC | 1 cut(s) | 106 |
| Hpy166II | GTNNAC | 1 cut(s) | 197 |
| Hpy188III | TCNNGA | 3 cut(s) | 110, 116, 140 |
| Hpy8I | GTNNAC | 1 cut(s) | 197 |
| Hpy99I | CGWCG | 1 cut(s) | 19 |
| HpyAV | CCTTC | 2 cut(s) | 340, 428 |
| HpyCH4III | ACNGT | 2 cut(s) | 30, 64 |
| HpyCH4V | TGCA | 7 cut(s) | 60, 245, 305, 311, 317, 329, 335 |
| HpyF10VI | GCNNNNNNNGC | 4 cut(s) | 161, 167, 308, 371 |
| HpyF3I | CTNAG | 1 cut(s) | 187 |
| Kzo9I | GATC | 2 cut(s) | 112, 136 |
| LguI | GCTCTTC | 1 cut(s) | 81 |
| LmnI | GCTCC | 1 cut(s) | 349 |
| LpnPI | CCDG | 2 cut(s) | 165, 269 |
| Lsp1109I | GCAGC | 3 cut(s) | 148, 286, 289 |
| LweI | GCATC | 1 cut(s) | 232 |
| MaeI | CTAG | 2 cut(s) | 476, 485 |
| MaeIII | GTNAC | 2 cut(s) | 258, 400 |
| MalI | GATC | 2 cut(s) | 114, 138 |
| MboI | GATC | 2 cut(s) | 112, 136 |
| MboII | GAAGA | 4 cut(s) | 98, 276, 279, 282 |
| MfeI | CAATTG | 2 cut(s) | 306, 312 |
| MflI | RGATCY | 2 cut(s) | 112, 136 |
| MhlI | GDGCHC | 1 cut(s) | 23 |
| MluCI | AATT | 3 cut(s) | 306, 312, 318 |
| MluI | ACGCGT | 1 cut(s) | 12 |
| MmeI | TCCRAC | 2 cut(s) | 347, 477 |
| MnlI | CCTC | 8 cut(s) | 52, 58, 112, 166, 212, 281, 336, 367 |
| MroXI | GAANNNNTTC | 1 cut(s) | 105 |
| MseI | TTAA | 2 cut(s) | 38, 78 |
| MunI | CAATTG | 2 cut(s) | 306, 312 |
| MvnI | CGCG | 1 cut(s) | 14 |
| MwoI | GCNNNNNNNGC | 4 cut(s) | 161, 167, 308, 371 |
| NdeII | GATC | 2 cut(s) | 112, 136 |
| NlaIV | GGNNCC | 1 cut(s) | 397 |
| NmeAIII | GCCGAG | 1 cut(s) | 189 |
| PciSI | GCTCTTC | 1 cut(s) | 81 |
| PdmI | GAANNNNTTC | 1 cut(s) | 105 |
| PfeI | GAWTC | 1 cut(s) | 106 |
| PkrI | GCNGC | 4 cut(s) | 163, 301, 304, 376 |
| PspN4I | GGNNCC | 1 cut(s) | 397 |
| PsuI | RGATCY | 2 cut(s) | 112, 136 |
| RsaI | GTAC | 1 cut(s) | 133 |
| RsaNI | GTAC | 1 cut(s) | 132 |
| SapI | GCTCTTC | 1 cut(s) | 81 |
| SaqAI | TTAA | 2 cut(s) | 38, 78 |
| SatI | GCNGC | 4 cut(s) | 162, 300, 303, 375 |
| Sau3AI | GATC | 2 cut(s) | 112, 136 |
| SduI | GDGCHC | 1 cut(s) | 23 |
| SetI | ASST | 6 cut(s) | 44, 123, 301, 468, 486, 490 |
| SfaNI | GCATC | 1 cut(s) | 232 |
| SmlI | CTYRAG | 2 cut(s) | 49, 116 |
| SmoI | CTYRAG | 2 cut(s) | 49, 116 |
| Sse9I | AATT | 3 cut(s) | 306, 312, 318 |
| SsiI | CCGC | 1 cut(s) | 374 |
| SspMI | CTAG | 2 cut(s) | 476, 485 |
| TaaI | ACNGT | 2 cut(s) | 30, 64 |
| TaqI | TCGA | 2 cut(s) | 17, 367 |
| TasI | AATT | 3 cut(s) | 306, 312, 318 |
| TatI | WGTACW | 1 cut(s) | 131 |
| TauI | GCSGC | 1 cut(s) | 377 |
| TfiI | GAWTC | 1 cut(s) | 106 |
| Tru1I | TTAA | 2 cut(s) | 38, 78 |
| Tru9I | TTAA | 2 cut(s) | 38, 78 |
| TscAI | CASTG | 3 cut(s) | 184, 252, 435 |
| TseI | GCWGC | 3 cut(s) | 161, 299, 302 |
| TspGWI | ACGGA | 1 cut(s) | 388 |
| TspRI | CASTG | 3 cut(s) | 184, 252, 435 |
| XmnI | GAANNNNTTC | 1 cut(s) | 105 |
| XspI | CTAG | 2 cut(s) | 476, 485 |