MD11G1298800.v1.1

Sodium hydrogen exchanger

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr11
OG0007582
Physical Location & Seq
Forward (+)
41533728 .. 41537978
4251 bp
Loading structure...
UTR
Exon/CDS
Intron
MD11G1298800.v1.1.491

Sequence Viewer

Length: 1638 bp
ATGGGGGTCTCTGCTGTGGTGAGATTGGGGGTGAGATCGGCCGCCAGTGAAGCTTCCGTAAATTCGATCACTTTGTTCGTGGTGCTCCTATGTTTATGCATTTTGATCGGTCATCTTCTGGAGAAGAATCGATGGATGACCGAATCAGTAACTGCGCTTCTCATCGGTCTTTGTACTGGAATTGTTATTCTACTAAATACCGAAGGCAAAAGCTCACACATCTTAGTGTTTAATGAAGATCTCTTCTTTATATATCTTCTGCCGCCTATTATATTTAATGCCGGATTTCAGGTGAAAAAGAAGAGGTTTTTTCAGAACTTCATGACAATCACGTTGTTGGGTGCTGTTGGAAGTTTGGTATCATTCGTCATTATATCGCTAGGTTCAATGCAGTTGTTCAAAAAATTGGACATTGGTTTCCTCGAGATGGGGGATTATCTTGCACTTGGAGCAATCTTCTCGGCTACAGATTCAGTTTGCACCCTGCAAGTACTTGATCAAGACGAGACACCTTTGCTCTACAGTCTAGTTTTTGGAGAAGGTGTTGTAAATGATGCCACGTCTGTGGCACTTTTCAACGCAATCCAGAAATTTGATCTCTCTCACATCAACTCAACAATTGCCATGGAGTTTAGCGGCAGTTTCTTAGTTCTCTTGTTCGCAAGCATGGTGCTTGGTGTAGCAGTTGGATTGCTTAGTGCATACATCATAAAGAAGTTGTACCTTGGCAGGCACTCGACTGATCGAGAAGTTGCTCTTATGATTCTAATGGCTTATTTGTCATACATGGTGGCAGAACTATTCAACCTAAGTGGCATTCTTACCGTTTTCTTTTGCGGGCTTGTTATGTCACACTATACCTGGCATAATGTAACTGAAAGTTCAAGAGTTACAACCAAGCATGCTTTTGCAACGTTCTCGTTTGTTTCTGAGATCTTCATCTTTCTATATGTTGGTATGGATGCCTTGGACATGGAGAAGTGGAAATTCGTAAAAGAGAGCCCCGGGACATCAATTGGAGTCAGTTCGATATTACTTGGCCTGGTTCTGGTTGGAAGAGCGGCTTTTGTATTTCCTCTATGTTTCTTATCAAACTTAACCAGGAGATCACAGACTGACAAAATCGGGTTTAAGCAACAGGTGACGGTATGGTGGGCAGGACTCATGCGTGGTGCTGTATCTGTGGCTCTTGCCTATAACTGGTTTACAATGTCAGGGCATACTCAACAGCGTGGAAACGCAGTCATGATCACTAGTACGATCACAGTAGTTCTCTTCACTAATGTGGTGTGCGGATTATTGACTAAGCCTCTCGTAAGGCTCTTGTTGCCGCAACAGAAACAGTTTGATAGCATTTTGATGTCCTCCGAGTCAGAGATGTCTCTGGCTATGCCGCTCCTCCTCGCTAACGGGGAAGATTCAAAGTCAAGTATGTCTAGTGATACCATGCCCCGTCCATCCAGCCTACGCATGTTCTTGACGACACCAACTCGTTCTGTCCATTACTATTGGAGAAAGTTTGATGATGGTTACATGCGTCCTGTCTTTGGCGGTAGAGGGTTCGTTCCTTATGCTCCTGGTTCACCCAATGAAAACATGCATCAATCGCTCCTCGGCGAGCAGATAATCGTTGAGTAA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
Na_H_Exchanger

Protein Analysis

546

Amino Acids

60.22

Weight (kDa)

7.63

Isoelectric Point (pI)

43.87

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
Na_H_Exchanger PF00999 29 - 440 4.2e-55 Sodium/hydrogen exchanger, transmembrane
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccBSI CCGCTC 2 cut(s) 1061, 1396
AciI CCGC 9 cut(s) 42, 263, 636, 837, 1061, 1293, 1331, 1394, 1551
AclI AACGTT 1 cut(s) 914
AcoI YGGCCR 1 cut(s) 39
AcsI RAATTY 3 cut(s) 61, 590, 986
AfaI GTAC 4 cut(s) 175, 492, 722, 1258
AfiI CCNNNNNNNGG 4 cut(s) 427, 1048, 1200, 1547
AgsI TTSAA 6 cut(s) 387, 400, 577, 805, 885, 1422
AhlI ACTAGT 1 cut(s) 1253
AjiI CACGTC 1 cut(s) 561
AjnI CCWGG 4 cut(s) 860, 1041, 1100, 1576
AleI CACNNNNGTG 2 cut(s) 563, 1283
AluBI AGCT 2 cut(s) 53, 213
AluI AGCT 2 cut(s) 53, 213
Alw21I GWGCWC 1 cut(s) 87
Alw26I GTCTC 3 cut(s) 13, 500, 1386
AlwNI CAGNNNCTG 1 cut(s) 152
Ama87I CYCGRG 2 cut(s) 422, 1004
AoxI GGCC 2 cut(s) 39, 1039
ApoI RAATTY 3 cut(s) 61, 590, 986
AspLEI GCGC 1 cut(s) 157
AsuC2I CCSGG 2 cut(s) 1005, 1006
AsuHPI GGTGA 5 cut(s) 31, 43, 304, 1153, 1575
AvaI CYCGRG 2 cut(s) 422, 1004
BanII GRGCYC 1 cut(s) 1004
BarI GAAGNNNNNNTAC 2 cut(s) 141, 173
Bbv12I GWGCWC 1 cut(s) 87
BccI CCATC 4 cut(s) 126, 421, 1465, 1520
BcgI CGANNNNNNTGC 6 cut(s) 88, 122, 441, 475, 900, 934
BciT130I CCWGG 4 cut(s) 862, 1043, 1102, 1578
BclI TGATCA 2 cut(s) 496, 1248
BcnI CCSGG 2 cut(s) 1005, 1006
BcoDI GTCTC 3 cut(s) 13, 500, 1386
BcuI ACTAGT 1 cut(s) 1253
BfaI CTAG 4 cut(s) 380, 527, 1254, 1437
BfmI CTRYAG 2 cut(s) 465, 520
BglII AGATCT 2 cut(s) 238, 933
BisI GCNGC 6 cut(s) 42, 263, 637, 1062, 1331, 1394
BlsI GCNGC 6 cut(s) 43, 264, 638, 1063, 1332, 1395
BmcAI AGTACT 1 cut(s) 492
Bme1390I CCNGG 6 cut(s) 862, 1005, 1006, 1043, 1102, 1578
BmeT110I CYCGRG 2 cut(s) 422, 1004
BmgBI CACGTC 1 cut(s) 561
BmrFI CCNGG 6 cut(s) 862, 1005, 1006, 1043, 1102, 1578
BmsI GCATC 3 cut(s) 544, 952, 1609
BpmI CTGGAG 1 cut(s) 140
BpuMI CCSGG 2 cut(s) 1005, 1006
Bsa29I ATCGAT 1 cut(s) 130
BsaBI GATNNNNATC 1 cut(s) 938
BsaI GGTCTC 1 cut(s) 13
BsaJI CCNNGG 6 cut(s) 624, 724, 966, 1003, 1004, 1612
BsaXI ACNNNNNCTCC 2 cut(s) 528, 558
Bsc4I CCNNNNNNNGG 4 cut(s) 427, 1048, 1200, 1547
Bse1I ACTGG 3 cut(s) 45, 181, 1205
Bse8I GATNNNNATC 1 cut(s) 938
BseBI CCWGG 4 cut(s) 862, 1043, 1102, 1578
BseCI ATCGAT 1 cut(s) 130
BseDI CCNNGG 6 cut(s) 624, 724, 966, 1003, 1004, 1612
BseGI GGATG 3 cut(s) 141, 967, 1457
BseJI GATNNNNATC 1 cut(s) 938
BseLI CCNNNNNNNGG 4 cut(s) 427, 1048, 1200, 1547
BseMII CTCAG 1 cut(s) 921
BseNI ACTGG 3 cut(s) 45, 181, 1205
BseRI GAGGAG 3 cut(s) 1388, 1391, 1601
BseX3I CGGCCG 1 cut(s) 39
Bsh1285I CGRYCG 1 cut(s) 42
BshFI GGCC 2 cut(s) 41, 1041
BshVI ATCGAT 1 cut(s) 130
BsiEI CGRYCG 1 cut(s) 42
BsiHKAI GWGCWC 1 cut(s) 87
BsiHKCI CYCGRG 2 cut(s) 422, 1004
BsiSI CCGG 2 cut(s) 282, 1005
BslFI GGGAC 1 cut(s) 1021
BslI CCNNNNNNNGG 4 cut(s) 427, 1048, 1200, 1547
BsmAI GTCTC 3 cut(s) 13, 500, 1386
BsmFI GGGAC 1 cut(s) 1021
BsmI GAATGC 1 cut(s) 816
BsnI GGCC 2 cut(s) 41, 1041
Bso31I GGTCTC 1 cut(s) 13
BsoBI CYCGRG 2 cut(s) 422, 1004
Bsp1286I GDGCHC 2 cut(s) 87, 1004
Bsp19I CCATGG 1 cut(s) 624
BspACI CCGC 9 cut(s) 42, 263, 636, 837, 1061, 1293, 1331, 1394, 1551
BspANI GGCC 2 cut(s) 41, 1041
BspCNI CTCAG 1 cut(s) 922
BspDI ATCGAT 1 cut(s) 130
BspHI TCATGA 2 cut(s) 321, 1245
BspQI GCTCTTC 1 cut(s) 1051
BspTNI GGTCTC 1 cut(s) 13
BsrBI CCGCTC 2 cut(s) 1061, 1396
BsrI ACTGG 3 cut(s) 45, 181, 1205
BssECI CCNNGG 6 cut(s) 624, 724, 966, 1003, 1004, 1612
BssT1I CCWWGG 3 cut(s) 624, 724, 966
Bst2UI CCWGG 4 cut(s) 862, 1043, 1102, 1578
Bst4CI ACNGT 5 cut(s) 524, 826, 1147, 1267, 1344
Bst6I CTCTTC 4 cut(s) 248, 296, 1051, 1280
BstC8I GCNNGC 5 cut(s) 664, 731, 839, 903, 1619
BstDEI CTNAG 6 cut(s) 223, 646, 695, 809, 930, 1305
BstDSI CCRYGG 1 cut(s) 624
BstF5I GGATG 3 cut(s) 141, 967, 1457
BstHHI GCGC 1 cut(s) 157
BstMAI GTCTC 3 cut(s) 13, 500, 1386
BstMCI CGRYCG 1 cut(s) 42
BstMWI GCNNNNNNNGC 4 cut(s) 50, 449, 1327, 1606
BstNI CCWGG 4 cut(s) 862, 1043, 1102, 1578
BstNSI RCATGY 4 cut(s) 905, 1474, 1537, 1600
BstSCI CCNGG 6 cut(s) 860, 1003, 1004, 1041, 1100, 1576
BstSFI CTRYAG 2 cut(s) 465, 520
BstX2I RGATCY 2 cut(s) 238, 933
BstXI CCANNNNNNTGG 1 cut(s) 565
BstYI RGATCY 2 cut(s) 238, 933
BstZI CGGCCG 1 cut(s) 39
Bsu15I ATCGAT 1 cut(s) 130
BsuRI GGCC 2 cut(s) 41, 1041
BsuTUI ATCGAT 1 cut(s) 130
BtgI CCRYGG 1 cut(s) 624
BtrI CACGTC 1 cut(s) 561
BtsCI GGATG 3 cut(s) 141, 967, 1457
BtsIMutI CAGTG 1 cut(s) 52
Cac8I GCNNGC 5 cut(s) 664, 731, 839, 903, 1619
CaiI CAGNNNCTG 1 cut(s) 152
CciI TCATGA 2 cut(s) 321, 1245
CfoI GCGC 1 cut(s) 157
Cfr9I CCCGGG 1 cut(s) 1004
ClaI ATCGAT 1 cut(s) 130
CseI GACGC 1 cut(s) 1526
Csp6I GTAC 4 cut(s) 174, 491, 721, 1257
CspCI CAANNNNNGTGG 2 cut(s) 793, 828
CviQI GTAC 4 cut(s) 174, 491, 721, 1257
DdeI CTNAG 6 cut(s) 223, 646, 695, 809, 930, 1305
EaeI YGGCCR 1 cut(s) 39
EagI CGGCCG 1 cut(s) 39
Eam1104I CTCTTC 4 cut(s) 248, 296, 1051, 1280
EarI CTCTTC 4 cut(s) 248, 296, 1051, 1280
EclXI CGGCCG 1 cut(s) 39
Eco130I CCWWGG 3 cut(s) 624, 724, 966
Eco24I GRGCYC 1 cut(s) 1004
Eco31I GGTCTC 1 cut(s) 13
Eco52I CGGCCG 1 cut(s) 39
Eco88I CYCGRG 2 cut(s) 422, 1004
EcoRII CCWGG 4 cut(s) 860, 1041, 1100, 1576
EcoT14I CCWWGG 3 cut(s) 624, 724, 966
EcoT22I ATGCAT 2 cut(s) 101, 1602
EcoT38I GRGCYC 1 cut(s) 1004
ErhI CCWWGG 3 cut(s) 624, 724, 966
FalI AAGNNNNNCTT 4 cut(s) 741, 773, 1048, 1080
FaqI GGGAC 1 cut(s) 1021
FauI CCCGC 1 cut(s) 830
FbaI TGATCA 2 cut(s) 496, 1248
Fnu4HI GCNGC 6 cut(s) 42, 263, 637, 1062, 1331, 1394
FokI GGATG 3 cut(s) 148, 974, 1444
FriOI GRGCYC 1 cut(s) 1004
Fsp4HI GCNGC 6 cut(s) 42, 263, 637, 1062, 1331, 1394
FspBI CTAG 4 cut(s) 380, 527, 1254, 1437
GlaI GCGC 1 cut(s) 156
GluI GCNGC 6 cut(s) 42, 263, 637, 1062, 1331, 1394
GsuI CTGGAG 1 cut(s) 140
HaeIII GGCC 2 cut(s) 41, 1041
HapII CCGG 2 cut(s) 282, 1005
HgaI GACGC 1 cut(s) 1526
HhaI GCGC 1 cut(s) 157
Hin6I GCGC 1 cut(s) 155
HinP1I GCGC 1 cut(s) 155
HindIII AAGCTT 1 cut(s) 51
HinfI GANTC 8 cut(s) 127, 143, 470, 763, 1020, 1161, 1370, 1418
HpaII CCGG 2 cut(s) 282, 1005
HphI GGTGA 5 cut(s) 31, 43, 304, 1153, 1575
Hpy166II GTNNAC 2 cut(s) 1206, 1583
Hpy188I TCNGA 4 cut(s) 315, 931, 1369, 1375
Hpy188III TCNNGA 9 cut(s) 119, 322, 424, 500, 586, 746, 885, 1246, 1477
Hpy8I GTNNAC 2 cut(s) 1206, 1583
HpyAV CCTTC 2 cut(s) 197, 533
HpyCH4III ACNGT 5 cut(s) 524, 826, 1147, 1267, 1344
HpyCH4IV ACGT 3 cut(s) 332, 560, 914
HpyCH4V TGCA 8 cut(s) 99, 391, 443, 480, 487, 701, 911, 1600
HpyF10VI GCNNNNNNNGC 4 cut(s) 50, 449, 1327, 1606
HpyF3I CTNAG 6 cut(s) 223, 646, 695, 809, 930, 1305
HpySE526I ACGT 3 cut(s) 332, 560, 914
HspAI GCGC 1 cut(s) 155
Ksp22I TGATCA 2 cut(s) 496, 1248
LguI GCTCTTC 1 cut(s) 1051
LmnI GCTCC 5 cut(s) 90, 449, 1401, 1579, 1614
LweI GCATC 3 cut(s) 544, 952, 1609
MaeI CTAG 4 cut(s) 380, 527, 1254, 1437
MaeII ACGT 3 cut(s) 332, 560, 914
MaeIII GTNAC 6 cut(s) 148, 849, 871, 889, 1141, 1529
MbiI CCGCTC 2 cut(s) 1061, 1396
MfeI CAATTG 2 cut(s) 618, 1014
MflI RGATCY 2 cut(s) 238, 933
MhlI GDGCHC 2 cut(s) 87, 1004
MluCI AATT 7 cut(s) 61, 180, 404, 590, 618, 986, 1014
MlyI GAGTC 3 cut(s) 1029, 1155, 1379
MmeI TCCRAC 3 cut(s) 328, 667, 1033
MnlI CCTC 9 cut(s) 297, 431, 1086, 1320, 1375, 1409, 1412, 1550, 1622
Mph1103I ATGCAT 2 cut(s) 101, 1602
MseI TTAA 4 cut(s) 231, 276, 1097, 1131
MslI CAYNNNNRTG 4 cut(s) 224, 563, 1283, 1358
MspI CCGG 2 cut(s) 282, 1005
MspR9I CCNGG 6 cut(s) 862, 1005, 1006, 1043, 1102, 1578
MunI CAATTG 2 cut(s) 618, 1014
Mva1269I GAATGC 1 cut(s) 816
MvaI CCWGG 4 cut(s) 862, 1043, 1102, 1578
MwoI GCNNNNNNNGC 4 cut(s) 50, 449, 1327, 1606
NciI CCSGG 2 cut(s) 1005, 1006
NcoI CCATGG 1 cut(s) 624
NmeAIII GCCGAG 2 cut(s) 440, 1593
NmuCI GTSAC 2 cut(s) 849, 1141
NsiI ATGCAT 2 cut(s) 101, 1602
NspI RCATGY 4 cut(s) 905, 1474, 1537, 1600
OliI CACNNNNGTG 2 cut(s) 563, 1283
PaeI GCATGC 1 cut(s) 905
PaeR7I CTCGAG 1 cut(s) 422
PagI TCATGA 2 cut(s) 321, 1245
PciSI GCTCTTC 1 cut(s) 1051
PctI GAATGC 1 cut(s) 816
PfeI GAWTC 5 cut(s) 127, 143, 470, 763, 1418
PkrI GCNGC 6 cut(s) 43, 264, 638, 1063, 1332, 1395
PleI GAGTC 3 cut(s) 1028, 1155, 1378
PpsI GAGTC 3 cut(s) 1028, 1155, 1378
Psp1406I AACGTT 1 cut(s) 914
Psp6I CCWGG 4 cut(s) 860, 1041, 1100, 1576
PspGI CCWGG 4 cut(s) 860, 1041, 1100, 1576
PstNI CAGNNNCTG 1 cut(s) 152
PsuI RGATCY 2 cut(s) 238, 933
RsaI GTAC 4 cut(s) 175, 492, 722, 1258
RsaNI GTAC 4 cut(s) 174, 491, 721, 1257
RseI CAYNNNNRTG 4 cut(s) 224, 563, 1283, 1358
SapI GCTCTTC 1 cut(s) 1051
SaqAI TTAA 4 cut(s) 231, 276, 1097, 1131
SatI GCNGC 6 cut(s) 42, 263, 637, 1062, 1331, 1394
ScaI AGTACT 1 cut(s) 492
SchI GAGTC 3 cut(s) 1029, 1155, 1379
ScrFI CCNGG 6 cut(s) 862, 1005, 1006, 1043, 1102, 1578
SduI GDGCHC 2 cut(s) 87, 1004
SfaNI GCATC 3 cut(s) 544, 952, 1609
SfcI CTRYAG 2 cut(s) 465, 520
Sfr274I CTCGAG 1 cut(s) 422
SlaI CTCGAG 1 cut(s) 422
SmaI CCCGGG 1 cut(s) 1006
SmiMI CAYNNNNRTG 4 cut(s) 224, 563, 1283, 1358
SmlI CTYRAG 1 cut(s) 422
SmoI CTYRAG 1 cut(s) 422
SpeI ACTAGT 1 cut(s) 1253
SphI GCATGC 1 cut(s) 905
Sse9I AATT 7 cut(s) 61, 180, 404, 590, 618, 986, 1014
SsiI CCGC 9 cut(s) 42, 263, 636, 837, 1061, 1293, 1331, 1394, 1551
SspMI CTAG 4 cut(s) 380, 527, 1254, 1437
StyD4I CCNGG 6 cut(s) 860, 1003, 1004, 1041, 1100, 1576
StyI CCWWGG 3 cut(s) 624, 724, 966
TaaI ACNGT 5 cut(s) 524, 826, 1147, 1267, 1344
TaiI ACGT 3 cut(s) 335, 563, 917
TaqI TCGA 6 cut(s) 65, 130, 423, 737, 745, 1028
TaqII GACCGA 3 cut(s) 98, 155, 155
TasI AATT 7 cut(s) 61, 180, 404, 590, 618, 986, 1014
TatI WGTACW 2 cut(s) 173, 490
TauI GCSGC 6 cut(s) 44, 265, 639, 1064, 1333, 1396
TfiI GAWTC 5 cut(s) 127, 143, 470, 763, 1418
Tru1I TTAA 4 cut(s) 231, 276, 1097, 1131
Tru9I TTAA 4 cut(s) 231, 276, 1097, 1131
TscAI CASTG 1 cut(s) 52
TseFI GTSAC 2 cut(s) 849, 1141
Tsp45I GTSAC 2 cut(s) 849, 1141
TspDTI ATGAA 4 cut(s) 249, 310, 928, 1605
TspGWI ACGGA 1 cut(s) 46
TspMI CCCGGG 1 cut(s) 1004
TspRI CASTG 1 cut(s) 52
XapI RAATTY 3 cut(s) 61, 590, 986
XceI RCATGY 4 cut(s) 905, 1474, 1537, 1600
XhoI CTCGAG 1 cut(s) 422
XmaI CCCGGG 1 cut(s) 1004
XspI CTAG 4 cut(s) 380, 527, 1254, 1437
ZrmI AGTACT 1 cut(s) 492
Zsp2I ATGCAT 2 cut(s) 101, 1602
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.