Basic Information

Type: gene

Biological Identity

Species

malus_domestica

Chromosome

Chr02

Orthogroup ID

OG0005013

Physical Location & Seq

Genomic Coordinates Reverse (-)

1548373 .. 1552372

Gene Structure 4000 bp

Loading structure...

UTR

Exon/CDS

Intron

Transcript / Protein ID

MD02G1022200.v1.1.491

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1587 bp

ATGGGAGTTGGGCAGATTACCCCGTTTAGAATGGGCATCGCAGTGTTAAGTCTGTTGCTGCAATTGCCAGCAATCTTTGCATCCGAGTTTGTCATACAGTCAAAGGATTGTAGTGATCACATTGCCTATTCAAGCTCTCATGGTCATGAATTGTTTTACATAAACGGGAATTCAGTAGAGAAAACTATATTCTGCACAGCTCTTCGGACATACTATGCAAATGGTTGCATTTTAGAAGGCAACCTTGGAAGTTACCATTGTCTATCAGACCCTTCACTAGTTGATTTTACCTTGAGGACCGGGAGGAAACTTCTGCAGAAGGAGTCAAAGGATAAATCCACTTTCGACAACAGAGAGGAAAAAAATGATTTTGCTTCTATGTCTACAACGACAAGGGTTGGAATAGCAGCAAGTGGAATGTTTCTCACGTGTTGTGCTTTTCTATGTCCTTGCTTTTTTAAGAAAAGGAGAGATAGCGTGCACGGAGTTCTTGCAAGGGAGCCAAATTCAATGGATTCAGGTTTTTCTTTTGAGGTGAGTTCTTCAGATCCTGAAAAGATCCTGGCCAGTCCGCATCGTGTGCCCCCTAGTCCACATCATGTGCCCCCTAGTCCACATCGTGTGCCACCTAGTCCTAGATTTTCAATGTCTCCAAAGCCCGGTAAAATTGGATCAGTACATCTCAGTTTGAATCAGATTGCAAAAGTAACTCGCAACTTCTCTCAATCGCAACAAGTAGGTGAAGGAGGTTTTGGAACTGTGTACAAGGCTCGGTTAGATGATGGCCAAGTGGTTTCTATTAAACGTGCAAAGAAGGAACACTTTGAGAATTTGCAAACTGAATTCGGCAGTGAAGTTGAACTGCTTGCCAAAATTGATCATAGGAATCTTGTAAAGCTACTAGGTTATGTTGATGAAGGAAATGAGCGTCTTATCATTACAGAGTATGTGGCGAATGGTACTCTTAGAGAACATCTGGATTGTCTGCATGGGAAAATCCTAGAGTTCAACCAGCGACTTGAAATTGCTATCGATGTTGCTCATGCCCTTACCTATCTTCACACATATTCTGAAAAACAAATCATCCATCGAGATGTGAAGTCCTCCAACATTCTTCTCACAGAAAGCATGAGAGCCAAAGTGGCAGATTTTGGATTTGCAAGGCTTGGCCCGGTGGACACAGATCAAACACACATTTCAACCAAAGTGAAAGGAACTGTCGGTTATCTTGACCCTGAGTATATGAAAACCTATCAACTCACCCCGAAAAGTGATGTTTACTCGTTCGGGATCTTACTAATAGAAATTTTGACTGGCCGTCGTCCAGTGGAGTTGAAGAGACCTGTTGAAGAGCGGGTAACACTCAGATGGGCCTTCAAGAAGTTGAATGAAGGGAAGGTGGTGGAATTGGCTGATCCTTTTATGGAGGAAACTATAGATGCAGAGGTTCTGATGAAAATCTTTGATCTGGCGATCCAATGTGCAGCCCCCATCCGAGTTGATAGACCGGACATGAAATCGGTGGGAGAGCAGTTGTGGACAATAAGGGCGGACTACCTTAGAAGTGTCAAGGCAAGGGCACAGTAA

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

No ontology terms assigned.

KEGG Pathways

Metabolic & Signaling

ko04010 ko04064 ko04620 ko04621 ko04624 ko04722 ko05133 ko05140 ko05142 ko05145 ko05152 ko05162 ko05164 map04010 map04064 map04620 map04621 map04624 map04722 map05133 map05140 map05142 map05145 map05152 map05162 map05164

Pfam Domains

Protein Families

Pkinase Pkinase_Tyr

Protein Analysis

529

Amino Acids

59.2

Weight (kDa)

8.21

Isoelectric Point (pI)

42.79

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
Pkinase	PF00069	241 - 447	3.2e-46	Protein kinase domain
PK_Tyr_Ser-Thr	PF07714	242 - 512	4.9e-49	Protein tyrosine and serine/threonine kinase

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

iTOL Interactive Tree Of Life · Most popular EvolView Flexible annotations MEGA Desktop phylogenetics suite FigTree Desktop tree editor

Orthologous Genes (Group: OG0005013)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT2G11520
fragaria_vesca	FvH4_1g02470 FvH4_1g02470 FvH4_1g02470 FvH4_1g02470 FvH4_1g02470 FvH4_1g02470 FvH4_1g02470
malus_domestica	MD02G1022200.v1.1 MD15G1164700.v1.1
prunus_persica	Prupe.7G250000_v2.0.a1 Prupe.7G250000_v2.0.a1 Prupe.7G250000_v2.0.a1 Prupe.7G250000_v2.0.a1 Prupe.7G250000_v2.0.a1 Prupe.7G250000_v2.0.a1
pyrus_communis	pycom02g01910 pycom15g14770
rosa_chinensis	RchiOBHm_Chr2g0087441
rosa_laevigata	RLG00000015869
rosa_multiflora	Rmu_sc0006064.1_g000012
rosa_roxburghii	Rroxscaffold_2G00153530
rosa_rugosa	Rorug01G0475300 Rorug01G0475400 Rorug01G0475500
rosa_samantha	Rh2AG028800 Rh2BG029100 Rh2CG029100 Rh2DG028900
rosa_wichuraiana	Rw2G002300

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AccBSI	CCGCTC	1 cut(s)	1354
AccI	GTMKAC	1 cut(s)	383
AciI	CCGC	3 cut(s)	572, 1354, 1550
AclWI	GGATC	6 cut(s)	542, 553, 679, 1298, 1409, 1468
AcoI	YGGCCR	3 cut(s)	564, 784, 1315
AcsI	RAATTY	5 cut(s)	169, 505, 829, 842, 1305
AcuI	CTGAAG	1 cut(s)	528
AcvI	CACGTG	1 cut(s)	429
AdeI	CACNNNGTG	1 cut(s)	620
AfaI	GTAC	3 cut(s)	678, 764, 961
AfiI	CCNNNNNNNGG	1 cut(s)	659
AflIII	ACRYGT	1 cut(s)	428
AhdI	GACNNNNNGTC	1 cut(s)	1317
AhlI	ACTAGT	1 cut(s)	277
AjnI	CCWGG	1 cut(s)	561
AjuI	GAANNNNNNNTTGG	4 cut(s)	228, 260, 735, 767
AluBI	AGCT	3 cut(s)	135, 200, 898
AluI	AGCT	3 cut(s)	135, 200, 898
Alw21I	GWGCWC	1 cut(s)	483
Alw26I	GTCTC	2 cut(s)	654, 1333
Alw44I	GTGCAC	1 cut(s)	479
AlwI	GGATC	6 cut(s)	542, 553, 679, 1298, 1409, 1468
AlwNI	CAGNNNCTG	1 cut(s)	551
AoxI	GGCC	5 cut(s)	564, 784, 1168, 1315, 1371
ApaLI	GTGCAC	1 cut(s)	479
ApeKI	GCWGC	3 cut(s)	58, 407, 1484
ApoI	RAATTY	5 cut(s)	169, 505, 829, 842, 1305
AspS9I	GGNCC	3 cut(s)	297, 1169, 1371
AsuC2I	CCSGG	3 cut(s)	301, 660, 1172
AsuHPI	GGTGA	3 cut(s)	547, 752, 1252
AvaII	GGWCC	1 cut(s)	297
BaeGI	GKGCMC	4 cut(s)	483, 585, 606, 1582
BalI	TGGCCA	2 cut(s)	566, 786
BbrPI	CACGTG	1 cut(s)	429
Bbv12I	GWGCWC	1 cut(s)	483
BbvI	GCAGC	3 cut(s)	45, 419, 1496
BccI	CCATC	4 cut(s)	776, 1095, 1362, 1499
BceAI	ACGGC	1 cut(s)	1302
BciT130I	CCWGG	1 cut(s)	563
BclI	TGATCA	2 cut(s)	115, 877
BcnI	CCSGG	3 cut(s)	301, 660, 1172
BcoDI	GTCTC	2 cut(s)	654, 1333
BcuI	ACTAGT	1 cut(s)	277
BfaI	CTAG	7 cut(s)	278, 588, 609, 630, 636, 902, 1001
BfmI	CTRYAG	2 cut(s)	314, 1434
BglI	GCCNNNNNGGC	1 cut(s)	1142
BisI	GCNGC	3 cut(s)	59, 408, 1485
BlsI	GCNGC	3 cut(s)	60, 409, 1486
Bme1390I	CCNGG	4 cut(s)	301, 563, 660, 1172
Bme18I	GGWCC	1 cut(s)	297
BmeRI	GACNNNNNGTC	1 cut(s)	1317
BmgT120I	GGNCC	3 cut(s)	297, 1169, 1371
BmiI	GGNNCC	1 cut(s)	501
BmrFI	CCNGG	4 cut(s)	301, 563, 660, 1172
BmsI	GCATC	4 cut(s)	45, 89, 583, 1429
BpuEI	CTTGAG	1 cut(s)	313
BpuMI	CCSGG	3 cut(s)	301, 660, 1172
Bsa29I	ATCGAT	1 cut(s)	1032
BsaAI	YACGTR	1 cut(s)	429
BsaBI	GATNNNNATC	1 cut(s)	1457
BsaI	GGTCTC	1 cut(s)	1333
BsaJI	CCNNGG	1 cut(s)	244
BsaWI	WCCGGW	1 cut(s)	1507
Bsc4I	CCNNNNNNNGG	1 cut(s)	659
Bse1I	ACTGG	3 cut(s)	567, 1318, 1325
Bse3DI	GCAATG	1 cut(s)	120
Bse8I	GATNNNNATC	1 cut(s)	1457
BseBI	CCWGG	1 cut(s)	563
BseCI	ATCGAT	1 cut(s)	1032
BseDI	CCNNGG	1 cut(s)	244
BseGI	GGATG	3 cut(s)	80, 1083, 1491
BseJI	GATNNNNATC	1 cut(s)	1457
BseLI	CCNNNNNNNGG	1 cut(s)	659
BseMI	GCAATG	1 cut(s)	120
BseMII	CTCAG	3 cut(s)	697, 1227, 1378
BseNI	ACTGG	3 cut(s)	567, 1318, 1325
BseSI	GKGCMC	4 cut(s)	483, 585, 606, 1582
BseXI	GCAGC	3 cut(s)	45, 419, 1496
BsgI	GTGCAG	2 cut(s)	178, 1503
BshFI	GGCC	5 cut(s)	566, 786, 1170, 1317, 1373
BshVI	ATCGAT	1 cut(s)	1032
BsiHKAI	GWGCWC	1 cut(s)	483
BsiSI	CCGG	4 cut(s)	300, 660, 1172, 1508
BslI	CCNNNNNNNGG	1 cut(s)	659
BsmAI	GTCTC	2 cut(s)	654, 1333
BsnI	GGCC	5 cut(s)	566, 786, 1170, 1317, 1373
Bso31I	GGTCTC	1 cut(s)	1333
Bsp1286I	GDGCHC	4 cut(s)	483, 585, 606, 1582
Bsp1407I	TGTACA	1 cut(s)	762
BspACI	CCGC	3 cut(s)	572, 1354, 1550
BspANI	GGCC	5 cut(s)	566, 786, 1170, 1317, 1373
BspCNI	CTCAG	3 cut(s)	696, 1228, 1377
BspDI	ATCGAT	1 cut(s)	1032
BspHI	TCATGA	1 cut(s)	145
BspLI	GGNNCC	1 cut(s)	501
BspMAI	CTGCAG	1 cut(s)	318
BspPI	GGATC	6 cut(s)	542, 553, 679, 1298, 1409, 1468
BspQI	GCTCTTC	2 cut(s)	207, 1344
BspTNI	GGTCTC	1 cut(s)	1333
BsrBI	CCGCTC	1 cut(s)	1354
BsrDI	GCAATG	1 cut(s)	120
BsrGI	TGTACA	1 cut(s)	762
BsrI	ACTGG	3 cut(s)	567, 1318, 1325
BssECI	CCNNGG	1 cut(s)	244
BssT1I	CCWWGG	1 cut(s)	244
Bst2UI	CCWGG	1 cut(s)	563
Bst4CI	ACNGT	4 cut(s)	99, 760, 1219, 1584
Bst6I	CTCTTC	3 cut(s)	207, 1331, 1344
BstAPI	GCANNNNNTGC	2 cut(s)	77, 580
BstAUI	TGTACA	1 cut(s)	762
BstBAI	YACGTR	1 cut(s)	429
BstC8I	GCNNGC	3 cut(s)	69, 479, 867
BstDEI	CTNAG	5 cut(s)	683, 965, 1236, 1364, 1559
BstF5I	GGATG	3 cut(s)	80, 1083, 1491
BstMAI	GTCTC	2 cut(s)	654, 1333
BstMWI	GCNNNNNNNGC	4 cut(s)	64, 77, 580, 1142
BstNI	CCWGG	1 cut(s)	563
BstSCI	CCNGG	4 cut(s)	299, 561, 658, 1170
BstSFI	CTRYAG	2 cut(s)	314, 1434
BstSLI	GKGCMC	4 cut(s)	483, 585, 606, 1582
BstV1I	GCAGC	3 cut(s)	45, 419, 1496
BstX2I	RGATCY	3 cut(s)	547, 558, 1290
BstYI	RGATCY	3 cut(s)	547, 558, 1290
Bsu15I	ATCGAT	1 cut(s)	1032
BsuRI	GGCC	5 cut(s)	566, 786, 1170, 1317, 1373
BsuTUI	ATCGAT	1 cut(s)	1032
BtgZI	GCGATG	1 cut(s)	22
BtsCI	GGATG	3 cut(s)	80, 1083, 1491
BtsI	GCAGTG	2 cut(s)	48, 856
BtsIMutI	CAGTG	3 cut(s)	48, 856, 1332
Cac8I	GCNNGC	3 cut(s)	69, 479, 867
CaiI	CAGNNNCTG	1 cut(s)	551
CciI	TCATGA	1 cut(s)	145
Cfr13I	GGNCC	3 cut(s)	297, 1169, 1371
ClaI	ATCGAT	1 cut(s)	1032
CseI	GACGC	1 cut(s)	917
Csp6I	GTAC	3 cut(s)	677, 763, 960
CviAII	CATG	7 cut(s)	140, 146, 599, 989, 1043, 1129, 1513
CviQI	GTAC	3 cut(s)	677, 763, 960
DdeI	CTNAG	5 cut(s)	683, 965, 1236, 1364, 1559
DraIII	CACNNNGTG	1 cut(s)	620
DriI	GACNNNNNGTC	1 cut(s)	1317
EaeI	YGGCCR	3 cut(s)	564, 784, 1315
Eam1104I	CTCTTC	3 cut(s)	207, 1331, 1344
Eam1105I	GACNNNNNGTC	1 cut(s)	1317
EarI	CTCTTC	3 cut(s)	207, 1331, 1344
EciI	GGCGGA	1 cut(s)	1565
Eco130I	CCWWGG	1 cut(s)	244
Eco31I	GGTCTC	1 cut(s)	1333
Eco47I	GGWCC	1 cut(s)	297
Eco57I	CTGAAG	1 cut(s)	528
Eco72I	CACGTG	1 cut(s)	429
EcoRI	GAATTC	2 cut(s)	169, 842
EcoRII	CCWGG	1 cut(s)	561
EcoT14I	CCWWGG	1 cut(s)	244
ErhI	CCWWGG	1 cut(s)	244
FaeI	CATG	7 cut(s)	143, 149, 602, 992, 1046, 1132, 1516
FalI	AAGNNNNNCTT	4 cut(s)	228, 260, 806, 838
FatI	CATG	7 cut(s)	139, 145, 598, 988, 1042, 1128, 1512
FauI	CCCGC	1 cut(s)	1347
FbaI	TGATCA	2 cut(s)	115, 877
FblI	GTMKAC	1 cut(s)	383
Fnu4HI	GCNGC	3 cut(s)	59, 408, 1485
FokI	GGATG	3 cut(s)	67, 1070, 1478
Fsp4HI	GCNGC	3 cut(s)	59, 408, 1485
FspBI	CTAG	7 cut(s)	278, 588, 609, 630, 636, 902, 1001
GluI	GCNGC	3 cut(s)	59, 408, 1485
HaeIII	GGCC	5 cut(s)	566, 786, 1170, 1317, 1373
HapII	CCGG	4 cut(s)	300, 660, 1172, 1508
HgaI	GACGC	1 cut(s)	917
Hin1II	CATG	7 cut(s)	143, 149, 602, 992, 1046, 1132, 1516
HinfI	GANTC	4 cut(s)	323, 515, 691, 886
HpaII	CCGG	4 cut(s)	300, 660, 1172, 1508
HphI	GGTGA	3 cut(s)	547, 752, 1252
Hpy166II	GTNNAC	8 cut(s)	384, 481, 593, 614, 763, 1177, 1279, 1539
Hpy188I	TCNGA	9 cut(s)	85, 207, 268, 547, 696, 1072, 1367, 1452, 1496
Hpy188III	TCNNGA	7 cut(s)	146, 551, 977, 1091, 1229, 1288, 1378
Hpy8I	GTNNAC	8 cut(s)	384, 481, 593, 614, 763, 1177, 1279, 1539
Hpy99I	CGWCG	1 cut(s)	1323
HpyAV	CCTTC	9 cut(s)	230, 282, 313, 737, 808, 911, 1384, 1385, 1390
HpyCH4III	ACNGT	4 cut(s)	99, 760, 1219, 1584
HpyCH4IV	ACGT	2 cut(s)	428, 805
HpyF10VI	GCNNNNNNNGC	4 cut(s)	64, 77, 580, 1142
HpyF3I	CTNAG	5 cut(s)	683, 965, 1236, 1364, 1559
HpySE526I	ACGT	2 cut(s)	428, 805
Hsp92II	CATG	7 cut(s)	143, 149, 602, 992, 1046, 1132, 1516
Ksp22I	TGATCA	2 cut(s)	115, 877
LguI	GCTCTTC	2 cut(s)	207, 1344
LmnI	GCTCC	1 cut(s)	499
Lsp1109I	GCAGC	3 cut(s)	45, 419, 1496
LweI	GCATC	4 cut(s)	45, 89, 583, 1429
MaeI	CTAG	7 cut(s)	278, 588, 609, 630, 636, 902, 1001
MaeII	ACGT	2 cut(s)	428, 805
MaeIII	GTNAC	3 cut(s)	251, 706, 1357
MbiI	CCGCTC	1 cut(s)	1354
MboII	GAAGA	6 cut(s)	194, 534, 1049, 1106, 1348, 1361
MfeI	CAATTG	1 cut(s)	62
MflI	RGATCY	3 cut(s)	547, 558, 1290
MhlI	GDGCHC	4 cut(s)	483, 585, 606, 1582
MlsI	TGGCCA	2 cut(s)	566, 786
MluNI	TGGCCA	2 cut(s)	566, 786
MlyI	GAGTC	1 cut(s)	332
MmeI	TCCRAC	2 cut(s)	379, 1131
MnlI	CCTC	8 cut(s)	288, 297, 349, 526, 740, 1114, 1420, 1438
Mox20I	TGGCCA	2 cut(s)	566, 786
MscI	TGGCCA	2 cut(s)	566, 786
MseI	TTAA	3 cut(s)	47, 459, 801
MslI	CAYNNNNRTG	4 cut(s)	41, 144, 1092, 1366
Msp20I	TGGCCA	2 cut(s)	566, 786
MspI	CCGG	4 cut(s)	300, 660, 1172, 1508
MspR9I	CCNGG	4 cut(s)	301, 563, 660, 1172
MunI	CAATTG	1 cut(s)	62
MvaI	CCWGG	1 cut(s)	563
MwoI	GCNNNNNNNGC	4 cut(s)	64, 77, 580, 1142
NciI	CCSGG	3 cut(s)	301, 660, 1172
NlaIII	CATG	7 cut(s)	143, 149, 602, 992, 1046, 1132, 1516
NlaIV	GGNNCC	1 cut(s)	501
PagI	TCATGA	1 cut(s)	145
PciSI	GCTCTTC	2 cut(s)	207, 1344
PfeI	GAWTC	3 cut(s)	515, 691, 886
PkrI	GCNGC	3 cut(s)	60, 409, 1486
PleI	GAGTC	1 cut(s)	331
PmaCI	CACGTG	1 cut(s)	429
PmlI	CACGTG	1 cut(s)	429
PpsI	GAGTC	1 cut(s)	331
Ppu21I	YACGTR	1 cut(s)	429
Psp6I	CCWGG	1 cut(s)	561
PspCI	CACGTG	1 cut(s)	429
PspGI	CCWGG	1 cut(s)	561
PspN4I	GGNNCC	1 cut(s)	501
PspPI	GGNCC	3 cut(s)	297, 1169, 1371
PstI	CTGCAG	1 cut(s)	318
PstNI	CAGNNNCTG	1 cut(s)	551
PsuI	RGATCY	3 cut(s)	547, 558, 1290
RsaI	GTAC	3 cut(s)	678, 764, 961
RsaNI	GTAC	3 cut(s)	677, 763, 960
RseI	CAYNNNNRTG	4 cut(s)	41, 144, 1092, 1366
SapI	GCTCTTC	2 cut(s)	207, 1344
SaqAI	TTAA	3 cut(s)	47, 459, 801
SatI	GCNGC	3 cut(s)	59, 408, 1485
Sau96I	GGNCC	3 cut(s)	297, 1169, 1371
SchI	GAGTC	1 cut(s)	332
ScrFI	CCNGG	4 cut(s)	301, 563, 660, 1172
SduI	GDGCHC	4 cut(s)	483, 585, 606, 1582
SfaNI	GCATC	4 cut(s)	45, 89, 583, 1429
SfcI	CTRYAG	2 cut(s)	314, 1434
SinI	GGWCC	1 cut(s)	297
SmiMI	CAYNNNNRTG	4 cut(s)	41, 144, 1092, 1366
SmlI	CTYRAG	1 cut(s)	292
SmoI	CTYRAG	1 cut(s)	292
SpeI	ACTAGT	1 cut(s)	277
SsiI	CCGC	3 cut(s)	572, 1354, 1550
SspMI	CTAG	7 cut(s)	278, 588, 609, 630, 636, 902, 1001
StyD4I	CCNGG	4 cut(s)	299, 561, 658, 1170
StyI	CCWWGG	1 cut(s)	244
TaaI	ACNGT	4 cut(s)	99, 760, 1219, 1584
TaiI	ACGT	2 cut(s)	431, 808
TaqI	TCGA	3 cut(s)	345, 1032, 1090
TatI	WGTACW	2 cut(s)	676, 762
TfiI	GAWTC	3 cut(s)	515, 691, 886
Tru1I	TTAA	3 cut(s)	47, 459, 801
Tru9I	TTAA	3 cut(s)	47, 459, 801
TscAI	CASTG	3 cut(s)	48, 856, 1332
TseI	GCWGC	3 cut(s)	58, 407, 1484
TspDTI	ATGAA	6 cut(s)	162, 930, 1259, 1404, 1469, 1529
TspGWI	ACGGA	1 cut(s)	498
TspRI	CASTG	3 cut(s)	48, 856, 1332
VneI	GTGCAC	1 cut(s)	479
VpaK11BI	GGWCC	1 cut(s)	297
XapI	RAATTY	5 cut(s)	169, 505, 829, 842, 1305
XmiI	GTMKAC	1 cut(s)	383
XspI	CTAG	7 cut(s)	278, 588, 609, 630, 636, 902, 1001

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.