pycom03g01460
MYB Family

Bromodomain-containing protein

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
pyrus_communis
Chr3
OG0006248
Physical Location & Seq
Forward (+)
1093490 .. 1096810
3321 bp
Loading structure...
UTR
Exon/CDS
Intron
N/A

Sequence Viewer

Length: 1164 bp
ATGGCTGGGGAACACGGAACGAGAACGCAACCATGGGGGACGTTAGAGGAGCTCTTACTCGTTTCCGCCGTGAACCGCCACGGCACCCAGAGTTGGGACTCCGTCGCCTTGGAGGTCGGGGGCCGATGCTCCGCCAAAGCGACGACGCTACTCACTGCTCTGAACTGTAGGGACAAGTTCGAGGACATCAAGCGACGGTTCGTATTGGGAGACGACGACGATTCGTCCGGGAGCCTGGGCGCGATGGTTGACAAGCTGCGAAGGCTGAGGGTTGAGGAGCTCCGACGCGAGGTCCGCCGTCGCGACGTTTCGATCGTGTCGTTGGAGTTGAAGGTGAAGAGGTTGGAGGAGGAGAGGGATCGCAGCTTGAAGGAGGACGCCGAGGCCACCAGTCCGAGCAAAGATCTCAAGCGCGGGGGAGAGGATCAACGGGATGGTTCGCCGGAGAACCTAGCCGGAAAAATGAACTCCGGCGAAGACTTCGGCTGGGACTTCAATTCCGACGAGCGTGAGAATCGATCCTTCAACGAGTCCAATTCGACGAGCCAAAGAGGCGCGGCGGAGAAACAGGCGGAGGGGAAAGAGGAGGAGCCCGGGCCGGAAGGAAACGAACCAGATCCGATGCGGGCTAAAATCCGGTCCGAACCGGATCGCGATTGCTCTGTTAACGGCAAAGTAGCAGACGATGACGACGAAGACAATCAAAACAACAAAAACGGCGATGATACAGCGAAGGCGAGTCAACTCGACGACTCGAGCGAGTTCTGGGAATCCGGTGGCGAGTCGAAGCGGGAGGGAAAAAGAGGTCGTCGTGGTGGTGCGGCGGCGTCGAGGCAGCAGAACAGCGACGTGCAGAGCTCGGCGAGCTTGTCGAAGAGGAAACCACGTCGTGGCGGCGGAGGAGAGGGAGGAGGAGGAGGGAGTAGGAGTAGGAGTAGGAGTAGGAGCAGCAGCGGCGAAGAGGCCGAGGGTGACGAAGTATCTCCCGCCACCAGCAAAGGGGTTAAGCAGCTCAAGCTGGTTAAATCTGAGCCGTTGATCGATCATCCGGTCTCATCGGCTCGGCTCCGTATTCGAGCGGCGGCTTCGGAGCCAGGAATCAGAAAGGTACAAAAGTTTGATTCGGCAACACATGGACCTACGTATGATTCAATCCAAGCTTAA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
Bromodomain Myb_DNA-binding

Protein Analysis

388

Amino Acids

42.2

Weight (kDa)

5.54

Isoelectric Point (pI)

62.03

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
Myb_DNA-binding PF00249 10 - 44 3.7e-06 Myb-like DNA-binding domain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccB1I GGYRCC 1 cut(s) 83
AccB7I CCANNNNNTGG 1 cut(s) 890
AccBSI CCGCTC 1 cut(s) 1079
AccII CGCG 6 cut(s) 242, 288, 303, 414, 557, 654
AclWI GGATC 5 cut(s) 366, 432, 513, 611, 657
AcyI GRCGYC 2 cut(s) 378, 827
AdeI CACNNNGTG 1 cut(s) 890
AfaI GTAC 1 cut(s) 1110
AfiI CCNNNNNNNGG 5 cut(s) 93, 94, 289, 890, 999
AgsI TTSAA 5 cut(s) 331, 370, 496, 526, 1152
AhdI GACNNNNNGTC 2 cut(s) 223, 290
AjiI CACGTC 2 cut(s) 850, 887
AjnI CCWGG 2 cut(s) 234, 1093
AluBI AGCT 9 cut(s) 52, 256, 280, 366, 858, 867, 1012, 1018, 1160
AluI AGCT 9 cut(s) 52, 256, 280, 366, 858, 867, 1012, 1018, 1160
Alw21I GWGCWC 3 cut(s) 54, 282, 860
Alw26I GTCTC 2 cut(s) 204, 1057
AlwI GGATC 5 cut(s) 366, 432, 513, 611, 657
Ama87I CYCGRG 2 cut(s) 593, 754
AoxI GGCC 4 cut(s) 121, 384, 596, 963
ApeKI GCWGC 6 cut(s) 256, 363, 835, 948, 951, 1009
AspLEI GCGC 3 cut(s) 242, 414, 557
AspS9I GGNCC 5 cut(s) 121, 292, 596, 639, 1136
AsuC2I CCSGG 3 cut(s) 229, 594, 595
AsuHPI GGTGA 2 cut(s) 346, 983
AvaI CYCGRG 2 cut(s) 593, 754
AvaII GGWCC 3 cut(s) 292, 639, 1136
BaeI ACNNNNGTAYC 2 cut(s) 1100, 1133
BanI GGYRCC 1 cut(s) 83
BanII GRGCYC 4 cut(s) 54, 282, 594, 860
BbsI GAAGAC 2 cut(s) 483, 702
Bbv12I GWGCWC 3 cut(s) 54, 282, 860
BbvCI CCTCAGC 1 cut(s) 266
BbvI GCAGC 6 cut(s) 243, 375, 847, 960, 963, 1021
BccI CCATC 2 cut(s) 238, 428
BceAI ACGGC 6 cut(s) 53, 97, 282, 685, 733, 1018
BciT130I CCWGG 2 cut(s) 236, 1095
BcnI CCSGG 3 cut(s) 229, 594, 595
BcoDI GTCTC 2 cut(s) 204, 1057
BfaI CTAG 1 cut(s) 452
BfmI CTRYAG 1 cut(s) 166
BglI GCCNNNNNGGC 1 cut(s) 552
BglII AGATCT 1 cut(s) 403
Bme1390I CCNGG 5 cut(s) 229, 236, 594, 595, 1095
Bme18I GGWCC 3 cut(s) 292, 639, 1136
BmeRI GACNNNNNGTC 2 cut(s) 223, 290
BmeT110I CYCGRG 2 cut(s) 593, 754
BmgBI CACGTC 2 cut(s) 850, 887
BmgT120I GGNCC 5 cut(s) 121, 292, 596, 639, 1136
BmiI GGNNCC 6 cut(s) 85, 122, 233, 591, 1067, 1092
BmrFI CCNGG 5 cut(s) 229, 236, 594, 595, 1095
BmsI GCATC 2 cut(s) 116, 612
BpiI GAAGAC 2 cut(s) 483, 702
Bpu10I CCTNAGC 1 cut(s) 266
BpuEI CTTGAG 2 cut(s) 392, 998
BpuMI CCSGG 3 cut(s) 229, 594, 595
Bsa29I ATCGAT 2 cut(s) 517, 1041
BsaAI YACGTR 1 cut(s) 1143
BsaHI GRCGYC 2 cut(s) 378, 827
BsaI GGTCTC 1 cut(s) 1057
BsaJI CCNNGG 7 cut(s) 32, 79, 108, 235, 381, 593, 966
BsaWI WCCGGW 4 cut(s) 636, 646, 773, 1048
BsaXI ACNNNNNCTCC 6 cut(s) 913, 919, 925, 943, 949, 955
Bsc4I CCNNNNNNNGG 5 cut(s) 93, 94, 289, 890, 999
Bse1I ACTGG 1 cut(s) 390
BseBI CCWGG 2 cut(s) 236, 1095
BseCI ATCGAT 2 cut(s) 517, 1041
BseDI CCNNGG 7 cut(s) 32, 79, 108, 235, 381, 593, 966
BseGI GGATG 2 cut(s) 439, 1045
BseLI CCNNNNNNNGG 5 cut(s) 93, 94, 289, 890, 999
BseMII CTCAG 2 cut(s) 257, 1020
BseNI ACTGG 1 cut(s) 390
BseXI GCAGC 6 cut(s) 243, 375, 847, 960, 963, 1021
BseYI CCCAGC 2 cut(s) 5, 486
BsgI GTGCAG 1 cut(s) 872
Bsh1236I CGCG 6 cut(s) 242, 288, 303, 414, 557, 654
Bsh1285I CGRYCG 1 cut(s) 315
BshFI GGCC 4 cut(s) 123, 386, 598, 965
BshNI GGYRCC 1 cut(s) 83
BshVI ATCGAT 2 cut(s) 517, 1041
BsiEI CGRYCG 1 cut(s) 315
BsiHKAI GWGCWC 3 cut(s) 54, 282, 860
BsiHKCI CYCGRG 2 cut(s) 593, 754
BslFI GGGAC 4 cut(s) 52, 110, 185, 503
BslI CCNNNNNNNGG 5 cut(s) 93, 94, 289, 890, 999
BsmAI GTCTC 2 cut(s) 204, 1057
BsmBI CGTCTC 1 cut(s) 204
BsmFI GGGAC 4 cut(s) 52, 110, 185, 503
BsnI GGCC 4 cut(s) 123, 386, 598, 965
Bso31I GGTCTC 1 cut(s) 1057
BsoBI CYCGRG 2 cut(s) 593, 754
Bsp1286I GDGCHC 4 cut(s) 54, 282, 594, 860
Bsp143I GATC 9 cut(s) 312, 358, 403, 424, 518, 616, 649, 1038, 1042
Bsp19I CCATGG 1 cut(s) 32
Bsp68I TCGCGA 2 cut(s) 303, 654
BspANI GGCC 4 cut(s) 123, 386, 598, 965
BspCNI CTCAG 2 cut(s) 258, 1021
BspDI ATCGAT 2 cut(s) 517, 1041
BspFNI CGCG 6 cut(s) 242, 288, 303, 414, 557, 654
BspLI GGNNCC 6 cut(s) 85, 122, 233, 591, 1067, 1092
BspPI GGATC 5 cut(s) 366, 432, 513, 611, 657
BspT107I GGYRCC 1 cut(s) 83
BspTNI GGTCTC 1 cut(s) 1057
BsrBI CCGCTC 1 cut(s) 1079
BsrI ACTGG 1 cut(s) 390
BssECI CCNNGG 7 cut(s) 32, 79, 108, 235, 381, 593, 966
BssMI GATC 9 cut(s) 312, 358, 403, 424, 518, 616, 649, 1038, 1042
BssNI GRCGYC 2 cut(s) 378, 827
BssT1I CCWWGG 2 cut(s) 32, 108
Bst2UI CCWGG 2 cut(s) 236, 1095
Bst4CI ACNGT 2 cut(s) 167, 198
Bst6I CTCTTC 3 cut(s) 332, 869, 954
BstACI GRCGYC 2 cut(s) 378, 827
BstBAI YACGTR 1 cut(s) 1143
BstC8I GCNNGC 2 cut(s) 627, 865
BstDEI CTNAG 2 cut(s) 266, 1029
BstDSI CCRYGG 2 cut(s) 32, 79
BstF5I GGATG 2 cut(s) 439, 1045
BstFNI CGCG 6 cut(s) 242, 288, 303, 414, 557, 654
BstHHI GCGC 3 cut(s) 242, 414, 557
BstKTI GATC 9 cut(s) 315, 361, 406, 427, 521, 619, 652, 1041, 1045
BstMAI GTCTC 2 cut(s) 204, 1057
BstMBI GATC 9 cut(s) 312, 358, 403, 424, 518, 616, 649, 1038, 1042
BstMCI CGRYCG 1 cut(s) 315
BstMWI GCNNNNNNNGC 6 cut(s) 262, 294, 552, 864, 954, 1015
BstNI CCWGG 2 cut(s) 236, 1095
BstSCI CCNGG 5 cut(s) 227, 234, 592, 593, 1093
BstSFI CTRYAG 1 cut(s) 166
BstSNI TACGTA 1 cut(s) 1143
BstUI CGCG 6 cut(s) 242, 288, 303, 414, 557, 654
BstV1I GCAGC 6 cut(s) 243, 375, 847, 960, 963, 1021
BstV2I GAAGAC 2 cut(s) 483, 702
BstX2I RGATCY 2 cut(s) 403, 616
BstYI RGATCY 2 cut(s) 403, 616
Bsu15I ATCGAT 2 cut(s) 517, 1041
BsuRI GGCC 4 cut(s) 123, 386, 598, 965
BsuTUI ATCGAT 2 cut(s) 517, 1041
BtgI CCRYGG 2 cut(s) 32, 79
BtgZI GCGATG 2 cut(s) 257, 735
BtrI CACGTC 2 cut(s) 850, 887
BtsCI GGATG 2 cut(s) 439, 1045
BtsI GCAGTG 1 cut(s) 153
BtsIMutI CAGTG 1 cut(s) 153
BtuMI TCGCGA 2 cut(s) 303, 654
Cac8I GCNNGC 2 cut(s) 627, 865
CfoI GCGC 3 cut(s) 242, 414, 557
Cfr13I GGNCC 5 cut(s) 121, 292, 596, 639, 1136
Cfr9I CCCGGG 1 cut(s) 593
ClaI ATCGAT 2 cut(s) 517, 1041
CpoI CGGWCCG 1 cut(s) 639
CseI GACGC 4 cut(s) 154, 294, 386, 816
Csp6I GTAC 1 cut(s) 1109
CspI CGGWCCG 1 cut(s) 639
CviAII CATG 2 cut(s) 33, 1133
CviQI GTAC 1 cut(s) 1109
DdeI CTNAG 2 cut(s) 266, 1029
DpnI GATC 9 cut(s) 314, 360, 405, 426, 520, 618, 651, 1040, 1044
DpnII GATC 9 cut(s) 312, 358, 403, 424, 518, 616, 649, 1038, 1042
DraIII CACNNNGTG 1 cut(s) 890
DriI GACNNNNNGTC 2 cut(s) 223, 290
Eam1104I CTCTTC 3 cut(s) 332, 869, 954
Eam1105I GACNNNNNGTC 2 cut(s) 223, 290
EarI CTCTTC 3 cut(s) 332, 869, 954
EciI GGCGGA 6 cut(s) 55, 121, 284, 575, 587, 912
Ecl136II GAGCTC 3 cut(s) 52, 280, 858
Eco105I TACGTA 1 cut(s) 1143
Eco130I CCWWGG 2 cut(s) 32, 108
Eco24I GRGCYC 4 cut(s) 54, 282, 594, 860
Eco31I GGTCTC 1 cut(s) 1057
Eco47I GGWCC 3 cut(s) 292, 639, 1136
Eco53kI GAGCTC 3 cut(s) 52, 280, 858
Eco88I CYCGRG 2 cut(s) 593, 754
EcoICRI GAGCTC 3 cut(s) 52, 280, 858
EcoRII CCWGG 2 cut(s) 234, 1093
EcoT14I CCWWGG 2 cut(s) 32, 108
EcoT38I GRGCYC 4 cut(s) 54, 282, 594, 860
ErhI CCWWGG 2 cut(s) 32, 108
Esp3I CGTCTC 1 cut(s) 204
FaeI CATG 2 cut(s) 36, 1136
FaiI YATR 3 cut(s) 34, 1134, 1146
FaqI GGGAC 4 cut(s) 52, 110, 185, 503
FatI CATG 2 cut(s) 32, 1132
FauI CCCGC 4 cut(s) 407, 618, 783, 994
FokI GGATG 2 cut(s) 446, 1032
FriOI GRGCYC 4 cut(s) 54, 282, 594, 860
FspBI CTAG 1 cut(s) 452
GlaI GCGC 3 cut(s) 241, 413, 556
GsaI CCCAGC 2 cut(s) 9, 490
HaeIII GGCC 4 cut(s) 123, 386, 598, 965
HgaI GACGC 4 cut(s) 154, 294, 386, 816
HhaI GCGC 3 cut(s) 242, 414, 557
Hin1I GRCGYC 2 cut(s) 378, 827
Hin1II CATG 2 cut(s) 36, 1136
Hin6I GCGC 3 cut(s) 240, 412, 555
HinP1I GCGC 3 cut(s) 240, 412, 555
HincII GTYRAC 3 cut(s) 250, 667, 743
HindII GTYRAC 3 cut(s) 250, 667, 743
HindIII AAGCTT 1 cut(s) 1158
HpaI GTTAAC 1 cut(s) 667
HphI GGTGA 2 cut(s) 346, 983
Hpy166II GTNNAC 4 cut(s) 73, 250, 667, 743
Hpy188I TCNGA 9 cut(s) 162, 284, 396, 502, 621, 643, 1030, 1090, 1103
Hpy188III TCNNGA 2 cut(s) 302, 653
Hpy8I GTNNAC 4 cut(s) 73, 250, 667, 743
HpyAV CCTTC 6 cut(s) 255, 325, 364, 532, 596, 727
HpyCH4III ACNGT 2 cut(s) 167, 198
HpyCH4IV ACGT 5 cut(s) 41, 306, 849, 886, 1142
HpyCH4V TGCA 1 cut(s) 853
HpyF10VI GCNNNNNNNGC 6 cut(s) 262, 294, 552, 864, 954, 1015
HpyF3I CTNAG 2 cut(s) 266, 1029
HpySE526I ACGT 5 cut(s) 41, 306, 849, 886, 1142
Hsp92I GRCGYC 2 cut(s) 378, 827
Hsp92II CATG 2 cut(s) 36, 1136
HspAI GCGC 3 cut(s) 240, 412, 555
KspAI GTTAAC 1 cut(s) 667
Kzo9I GATC 9 cut(s) 312, 358, 403, 424, 518, 616, 649, 1038, 1042
LmnI GCTCC 9 cut(s) 49, 134, 231, 277, 285, 589, 945, 1071, 1090
Lsp1109I GCAGC 6 cut(s) 243, 375, 847, 960, 963, 1021
LweI GCATC 2 cut(s) 116, 612
MaeI CTAG 1 cut(s) 452
MaeII ACGT 5 cut(s) 41, 306, 849, 886, 1142
MaeIII GTNAC 1 cut(s) 971
MalI GATC 9 cut(s) 314, 360, 405, 426, 520, 618, 651, 1040, 1044
MbiI CCGCTC 1 cut(s) 1079
MboI GATC 9 cut(s) 312, 358, 403, 424, 518, 616, 649, 1038, 1042
MboII GAAGA 5 cut(s) 349, 488, 707, 886, 971
MflI RGATCY 2 cut(s) 403, 616
MhlI GDGCHC 4 cut(s) 54, 282, 594, 860
MluCI AATT 2 cut(s) 496, 535
MlyI GAGTC 5 cut(s) 92, 539, 746, 748, 791
MmeI TCCRAC 4 cut(s) 303, 307, 324, 525
MseI TTAA 4 cut(s) 666, 1005, 1023, 1162
MspA1I CMGCKG 1 cut(s) 954
MspR9I CCNGG 5 cut(s) 229, 236, 594, 595, 1095
MvaI CCWGG 2 cut(s) 236, 1095
MvnI CGCG 6 cut(s) 242, 288, 303, 414, 557, 654
MwoI GCNNNNNNNGC 6 cut(s) 262, 294, 552, 864, 954, 1015
NciI CCSGG 3 cut(s) 229, 594, 595
NcoI CCATGG 1 cut(s) 32
NdeII GATC 9 cut(s) 312, 358, 403, 424, 518, 616, 649, 1038, 1042
NlaIII CATG 2 cut(s) 36, 1136
NlaIV GGNNCC 6 cut(s) 85, 122, 233, 591, 1067, 1092
NmeAIII GCCGAG 4 cut(s) 406, 839, 991, 1042
NmuCI GTSAC 1 cut(s) 971
NruI TCGCGA 2 cut(s) 303, 654
PaeR7I CTCGAG 1 cut(s) 754
PcsI WCGNNNNNNNCGW 5 cut(s) 66, 312, 317, 690, 756
PfeI GAWTC 6 cut(s) 221, 514, 770, 1098, 1121, 1148
PflFI GACNNNGTC 1 cut(s) 101
PflMI CCANNNNNTGG 1 cut(s) 890
PfoI TCCNGGA 1 cut(s) 227
Ple19I CGATCG 1 cut(s) 315
PleI GAGTC 5 cut(s) 92, 538, 746, 747, 790
PpsI GAGTC 5 cut(s) 92, 538, 746, 747, 790
Ppu21I YACGTR 1 cut(s) 1143
Psp124BI GAGCTC 3 cut(s) 54, 282, 860
Psp6I CCWGG 2 cut(s) 234, 1093
PspFI CCCAGC 2 cut(s) 5, 486
PspGI CCWGG 2 cut(s) 234, 1093
PspN4I GGNNCC 6 cut(s) 85, 122, 233, 591, 1067, 1092
PspPI GGNCC 5 cut(s) 121, 292, 596, 639, 1136
PspXI VCTCGAGB 1 cut(s) 754
PsuI RGATCY 2 cut(s) 403, 616
PsyI GACNNNGTC 1 cut(s) 101
PvuI CGATCG 1 cut(s) 315
RruI TCGCGA 2 cut(s) 303, 654
RsaI GTAC 1 cut(s) 1110
RsaNI GTAC 1 cut(s) 1109
Rsr2I CGGWCCG 1 cut(s) 639
RsrII CGGWCCG 1 cut(s) 639
SacI GAGCTC 3 cut(s) 54, 282, 860
SaqAI TTAA 4 cut(s) 666, 1005, 1023, 1162
Sau3AI GATC 9 cut(s) 312, 358, 403, 424, 518, 616, 649, 1038, 1042
Sau96I GGNCC 5 cut(s) 121, 292, 596, 639, 1136
SchI GAGTC 5 cut(s) 92, 539, 746, 748, 791
ScrFI CCNGG 5 cut(s) 229, 236, 594, 595, 1095
SduI GDGCHC 4 cut(s) 54, 282, 594, 860
SfaNI GCATC 2 cut(s) 116, 612
SfcI CTRYAG 1 cut(s) 166
Sfr274I CTCGAG 1 cut(s) 754
SinI GGWCC 3 cut(s) 292, 639, 1136
SlaI CTCGAG 1 cut(s) 754
SmaI CCCGGG 1 cut(s) 595
SmlI CTYRAG 3 cut(s) 407, 754, 1013
SmoI CTYRAG 3 cut(s) 407, 754, 1013
SnaBI TACGTA 1 cut(s) 1143
SrfI GCCCGGGC 1 cut(s) 595
Sse9I AATT 2 cut(s) 496, 535
SspMI CTAG 1 cut(s) 452
SstI GAGCTC 3 cut(s) 54, 282, 860
StyD4I CCNGG 5 cut(s) 227, 234, 592, 593, 1093
StyI CCWWGG 2 cut(s) 32, 108
TaaI ACNGT 2 cut(s) 167, 198
TaiI ACGT 5 cut(s) 44, 309, 852, 889, 1145
TasI AATT 2 cut(s) 496, 535
TauI GCSGC 7 cut(s) 560, 824, 827, 897, 957, 1082, 1085
TfiI GAWTC 6 cut(s) 221, 514, 770, 1098, 1121, 1148
Tru1I TTAA 4 cut(s) 666, 1005, 1023, 1162
Tru9I TTAA 4 cut(s) 666, 1005, 1023, 1162
TscAI CASTG 1 cut(s) 160
TseFI GTSAC 1 cut(s) 971
TseI GCWGC 6 cut(s) 256, 363, 835, 948, 951, 1009
Tsp45I GTSAC 1 cut(s) 971
TspDTI ATGAA 1 cut(s) 479
TspGWI ACGGA 3 cut(s) 30, 91, 1058
TspMI CCCGGG 1 cut(s) 593
TspRI CASTG 1 cut(s) 160
Tth111I GACNNNGTC 1 cut(s) 101
Van91I CCANNNNNTGG 1 cut(s) 890
VpaK11BI GGWCC 3 cut(s) 292, 639, 1136
XhoI CTCGAG 1 cut(s) 754
XmaI CCCGGG 1 cut(s) 593
XspI CTAG 1 cut(s) 452
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.