Basic Information

Type: gene

Biological Identity

Species

pyrus_communis

Chromosome

Chr5

Orthogroup ID

OG0001574

Physical Location & Seq

Genomic Coordinates Forward (+)

3734441 .. 3740824

Gene Structure 6384 bp

Loading structure...

UTR

Exon/CDS

Intron

Transcript / Protein ID

pycom05g03240.4

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1056 bp

ATGGCCGCCACCGCCTCTTCCGCCGCAGCCAAACCCCTCCCTTCCTTGAACGTCTCGGCGGATTCTCCTCCTCCGAAACTCGCCCTCACGCTCGATCAGTACAAGTACTGCTCTCAGGCTCTCAAGCTCTTTAAGGGAAAGCTCCAGATGCGTGACCATATCAACCAGGAGTTCGCTCAGCTGCAGGCCAAGAGGATGACATCTTCTGAGAGGAAGAGAAATTGCACTGTGGCTCTTGACAATGTCAATTCGAGCAAAAACCGATACACCGATGTCGTGCCATTTGACAAAAATAGGGTTGTTCTCAACTCCTCGAAGGATTACAGACCTTCCGCAAGAGGTTACATCAACGCCAGCTTAATCACGACTAGTTCTTCCGAAAGCATTTCTCAGTTTATAGCAACACAAGGTCCACTTCCCCACACCTATGAGGATTTCTGGGAGATGGTACTTGAGCAACGCTGCCCGGTGGTCATCATGCTTACTCGTTTAATCGACTGTTACACGATGGTTAAATGTGGAGATTATTATCAGGCTGAAGATGGCCCTAGAGAATTCGGTAACATATGTATAAGCACTAAGTGGCTAAGAACTACTGACACTTCATTAGTATTACGCCTTTTGGAGGTCAATAATAAAGAGTCCGAGGAACCACCCATGTCTGTTTTGCACATTCAGTATCCTGAATGGCCTGACCATGGAGTTCCAAACAACACGATTGCTGTCCGTGAAATCTTGAAAAGATTATATAACGTGCCACCGAACCTTGGCCCAATTGTGGTGCATTGCAGTGCAGGTATTGGGAGAACTGGAACATACTGCACAATTCATAATACTGTGCAAAGAATTCTTGCTGGGGACATGTCTGCTTTAGATCTCGTTGATACAATAACCACATTTCGGTCTCAGCGAATTGGAATGGTCCAGACACTGGAGCAATTTTTTTTCTGTTATTCTGCCATCGTTGATGAATTGGAAGACCTCATCTCGGATTTGAATAGTGAAACGAGCTCAAATTCTTGTGTCCTAAAAGAAGATTGTCCGCAGCATTGTTAA

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0000188 GO:0001932 GO:0001933 GO:0003674 GO:0003824 GO:0004721 GO:0004725 GO:0005575 GO:0005622 GO:0005623 GO:0005634 GO:0005737 GO:0005886 GO:0006464 GO:0006469 GO:0006470 GO:0006793 GO:0006796 GO:0006807 GO:0007154 GO:0007165 GO:0008150 GO:0008152 GO:0009892 GO:0009966 GO:0009968 GO:0009987 GO:0010563 GO:0010605 GO:0010646 GO:0010648 GO:0016020 GO:0016311 GO:0016787 GO:0016788 GO:0016791 GO:0019220 GO:0019222 GO:0019538 GO:0023051 GO:0023052 GO:0023057 GO:0031323 GO:0031324 GO:0031347 GO:0031348 GO:0031399 GO:0031400 GO:0032268 GO:0032269 GO:0033549 GO:0033550 GO:0033673 GO:0035335 GO:0035556 GO:0036211 GO:0042325 GO:0042326 GO:0042578 GO:0043086 GO:0043170 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0043405 GO:0043407 GO:0043408 GO:0043409 GO:0043412 GO:0043549 GO:0044092 GO:0044237 GO:0044238 GO:0044260 GO:0044267 GO:0044424 GO:0044464 GO:0045859 GO:0045936 GO:0048519 GO:0048523 GO:0048583 GO:0048585 GO:0050789 GO:0050790 GO:0050794 GO:0050896 GO:0051171 GO:0051172 GO:0051174 GO:0051246 GO:0051248 GO:0051338 GO:0051348 GO:0051716 GO:0060255 GO:0065007 GO:0065009 GO:0071704 GO:0071900 GO:0071901 GO:0071944 GO:0080090 GO:0080134 GO:0140096 GO:1901564 GO:1902531 GO:1902532 GO:1990264

KEGG Pathways

Metabolic & Signaling

ko04520 ko04910 ko04931 map04520 map04910 map04931

Pfam Domains

Protein Families

Y_phosphatase

Protein Analysis

352

Amino Acids

39.41

Weight (kDa)

6.01

Isoelectric Point (pI)

45.19

Instability Index

Protein Domains (Pfam)

No Pfam domains detected for this protein.

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

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Orthologous Genes (Group: OG0001574)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT1G71860 AT1G71860 AT1G71860
fragaria_vesca	FvH4_2g12360 FvH4_2g12360 FvH4_2g12360 FvH4_2g12360 FvH4_5g14850 FvH4_5g14850 FvH4_5g14850
malus_domestica	MD05G1039700.v1.1 MD09G1287400.v1.1 MD10G1045300.v1.1
prunus_persica	Prupe.1G402600_v2.0.a1 Prupe.8G052200_v2.0.a1 Prupe.8G052200_v2.0.a1
pyrus_communis	pycom05g03240 pycom10g03170
rosa_chinensis	RchiOBHm_Chr3g0456471 RchiOBHm_Chr6g0272381 RchiOBHm_Chr7g0181531
rosa_laevigata	RLG00000005185 RLG00000013677 RLG00000025303
rosa_multiflora	Rmu_co8205282.1_g000001 Rmu_sc0004621.1_g000033 Rmu_sc0010043.1_g000002 Rmu_sc0023867.1_g000001 Rmu_sc0029422.1_g000002
rosa_roxburghii	Rroxscaffold_3G00271920 Rroxscaffold_6G00422730 Rroxscaffold_7G00196330
rosa_rugosa	Rorug03G0013200 Rorug03G0013300 Rorug06G0068700 Rorug06G0442100
rosa_samantha	Rh3AG073600 Rh3BG075500 Rh3CG075000 Rh3DG076800 Rh6AG184800 Rh6BG188100 Rh6DG177800 Rh7AG044200 Rh7BG043300 Rh7CG045100 Rh7DG043800
rosa_wichuraiana	Rw3G006310 Rw6G015980 Rw7G003660

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
Acc36I	ACCTGC	1 cut(s)	785
AccB7I	CCANNNNNTGG	1 cut(s)	931
AciI	CCGC	7 cut(s)	6, 12, 21, 24, 59, 333, 1043
AcoI	YGGCCR	1 cut(s)	3
AcsI	RAATTY	3 cut(s)	554, 846, 1015
AcuI	CTGAAG	1 cut(s)	558
AdeI	CACNNNGTG	1 cut(s)	582
AfaI	GTAC	3 cut(s)	101, 107, 450
AfiI	CCNNNNNNNGG	7 cut(s)	625, 698, 767, 778, 900, 931, 988
AflIII	ACRYGT	1 cut(s)	861
AgsI	TTSAA	3 cut(s)	49, 739, 997
AhlI	ACTAGT	1 cut(s)	368
AjnI	CCWGG	1 cut(s)	165
AluBI	AGCT	5 cut(s)	127, 142, 181, 357, 1011
AluI	AGCT	5 cut(s)	127, 142, 181, 357, 1011
Alw21I	GWGCWC	1 cut(s)	1013
Alw26I	GTCTC	2 cut(s)	58, 909
AlwNI	CAGNNNCTG	1 cut(s)	931
AoxI	GGCC	5 cut(s)	3, 186, 544, 689, 769
ApeKI	GCWGC	4 cut(s)	26, 181, 462, 1045
ApoI	RAATTY	3 cut(s)	554, 846, 1015
AspS9I	GGNCC	4 cut(s)	410, 545, 770, 922
AsuC2I	CCSGG	1 cut(s)	467
AvaII	GGWCC	2 cut(s)	410, 922
BanII	GRGCYC	1 cut(s)	1013
BbsI	GAAGAC	1 cut(s)	984
Bbv12I	GWGCWC	1 cut(s)	1013
BbvI	GCAGC	3 cut(s)	38, 168, 449
BccI	CCATC	4 cut(s)	439, 502, 536, 968
BciT130I	CCWGG	1 cut(s)	167
BciVI	GTATCC	1 cut(s)	690
BcnI	CCSGG	1 cut(s)	467
BcoDI	GTCTC	2 cut(s)	58, 909
BcuI	ACTAGT	1 cut(s)	368
BfaI	CTAG	2 cut(s)	369, 549
BfmI	CTRYAG	1 cut(s)	182
BfuAI	ACCTGC	1 cut(s)	785
BfuI	GTATCC	1 cut(s)	690
BglII	AGATCT	1 cut(s)	874
BisI	GCNGC	6 cut(s)	6, 24, 27, 182, 463, 1046
BlpI	GCTNAGC	1 cut(s)	177
BlsI	GCNGC	6 cut(s)	7, 25, 28, 183, 464, 1047
BmcAI	AGTACT	1 cut(s)	107
Bme1390I	CCNGG	2 cut(s)	167, 467
Bme18I	GGWCC	2 cut(s)	410, 922
BmgT120I	GGNCC	4 cut(s)	410, 545, 770, 922
BmiI	GGNNCC	1 cut(s)	651
BmrFI	CCNGG	2 cut(s)	167, 467
BmsI	GCATC	1 cut(s)	138
BpiI	GAAGAC	1 cut(s)	984
BpmI	CTGGAG	2 cut(s)	128, 953
Bpu1102I	GCTNAGC	1 cut(s)	177
BpuEI	CTTGAG	2 cut(s)	107, 473
BpuMI	CCSGG	1 cut(s)	467
BsaBI	GATNNNNATC	1 cut(s)	528
BsaI	GGTCTC	1 cut(s)	909
BsaJI	CCNNGG	3 cut(s)	645, 697, 766
Bsc4I	CCNNNNNNNGG	7 cut(s)	625, 698, 767, 778, 900, 931, 988
Bse1I	ACTGG	2 cut(s)	814, 936
Bse3DI	GCAATG	1 cut(s)	784
Bse8I	GATNNNNATC	1 cut(s)	528
BseBI	CCWGG	1 cut(s)	167
BseDI	CCNNGG	3 cut(s)	645, 697, 766
BseGI	GGATG	1 cut(s)	201
BseJI	GATNNNNATC	1 cut(s)	528
BseLI	CCNNNNNNNGG	7 cut(s)	625, 698, 767, 778, 900, 931, 988
BseMI	GCAATG	1 cut(s)	784
BseMII	CTCAG	5 cut(s)	128, 191, 198, 404, 920
BseNI	ACTGG	2 cut(s)	814, 936
BseRI	GAGGAG	3 cut(s)	57, 60, 301
BseXI	GCAGC	3 cut(s)	38, 168, 449
BseYI	CCCAGC	1 cut(s)	854
BsgI	GTGCAG	2 cut(s)	805, 813
BshFI	GGCC	5 cut(s)	5, 188, 546, 691, 771
BsiHKAI	GWGCWC	1 cut(s)	1013
BsiSI	CCGG	1 cut(s)	467
BslFI	GGGAC	1 cut(s)	872
BslI	CCNNNNNNNGG	7 cut(s)	625, 698, 767, 778, 900, 931, 988
BsmAI	GTCTC	2 cut(s)	58, 909
BsmBI	CGTCTC	1 cut(s)	58
BsmFI	GGGAC	1 cut(s)	872
BsnI	GGCC	5 cut(s)	5, 188, 546, 691, 771
Bso31I	GGTCTC	1 cut(s)	909
Bsp1286I	GDGCHC	1 cut(s)	1013
Bsp143I	GATC	2 cut(s)	94, 874
Bsp1720I	GCTNAGC	1 cut(s)	177
Bsp19I	CCATGG	1 cut(s)	697
BspACI	CCGC	7 cut(s)	6, 12, 21, 24, 59, 333, 1043
BspANI	GGCC	5 cut(s)	5, 188, 546, 691, 771
BspCNI	CTCAG	5 cut(s)	127, 190, 199, 403, 919
BspLI	GGNNCC	1 cut(s)	651
BspMAI	CTGCAG	1 cut(s)	186
BspMI	ACCTGC	1 cut(s)	785
BspTNI	GGTCTC	1 cut(s)	909
BsrDI	GCAATG	1 cut(s)	784
BsrI	ACTGG	2 cut(s)	814, 936
BssECI	CCNNGG	3 cut(s)	645, 697, 766
BssMI	GATC	2 cut(s)	94, 874
BssT1I	CCWWGG	2 cut(s)	697, 766
Bst2UI	CCWGG	1 cut(s)	167
Bst4CI	ACNGT	3 cut(s)	229, 500, 838
Bst6I	CTCTTC	2 cut(s)	22, 209
BstC8I	GCNNGC	2 cut(s)	186, 355
BstDEI	CTNAG	7 cut(s)	114, 177, 207, 390, 579, 587, 906
BstDSI	CCRYGG	1 cut(s)	697
BstENI	CCTNNNNNAGG	1 cut(s)	623
BstF5I	GGATG	1 cut(s)	201
BstKTI	GATC	2 cut(s)	97, 877
BstMAI	GTCTC	2 cut(s)	58, 909
BstMBI	GATC	2 cut(s)	94, 874
BstMWI	GCNNNNNNNGC	3 cut(s)	11, 20, 148
BstNI	CCWGG	1 cut(s)	167
BstNSI	RCATGY	1 cut(s)	865
BstSCI	CCNGG	2 cut(s)	165, 465
BstSFI	CTRYAG	1 cut(s)	182
BstV1I	GCAGC	3 cut(s)	38, 168, 449
BstV2I	GAAGAC	1 cut(s)	984
BstX2I	RGATCY	1 cut(s)	874
BstYI	RGATCY	1 cut(s)	874
BsuI	GTATCC	1 cut(s)	690
BsuRI	GGCC	5 cut(s)	5, 188, 546, 691, 771
BtgI	CCRYGG	1 cut(s)	697
BtsCI	GGATG	1 cut(s)	201
BtsI	GCAGTG	1 cut(s)	796
BtsIMutI	CAGTG	3 cut(s)	225, 796, 929
BveI	ACCTGC	1 cut(s)	785
Cac8I	GCNNGC	2 cut(s)	186, 355
CaiI	CAGNNNCTG	1 cut(s)	931
Cfr13I	GGNCC	4 cut(s)	410, 545, 770, 922
Csp6I	GTAC	3 cut(s)	100, 106, 449
CviAII	CATG	4 cut(s)	478, 658, 698, 862
CviQI	GTAC	3 cut(s)	100, 106, 449
DdeI	CTNAG	7 cut(s)	114, 177, 207, 390, 579, 587, 906
DpnI	GATC	2 cut(s)	96, 876
DpnII	GATC	2 cut(s)	94, 874
DraIII	CACNNNGTG	1 cut(s)	582
EaeI	YGGCCR	1 cut(s)	3
Eam1104I	CTCTTC	2 cut(s)	22, 209
EarI	CTCTTC	2 cut(s)	22, 209
EciI	GGCGGA	2 cut(s)	10, 74
Ecl136II	GAGCTC	1 cut(s)	1011
Eco130I	CCWWGG	2 cut(s)	697, 766
Eco24I	GRGCYC	1 cut(s)	1013
Eco31I	GGTCTC	1 cut(s)	909
Eco47I	GGWCC	2 cut(s)	410, 922
Eco53kI	GAGCTC	1 cut(s)	1011
Eco57I	CTGAAG	1 cut(s)	558
EcoICRI	GAGCTC	1 cut(s)	1011
EcoNI	CCTNNNNNAGG	1 cut(s)	623
EcoRI	GAATTC	2 cut(s)	554, 846
EcoRII	CCWGG	1 cut(s)	165
EcoT14I	CCWWGG	2 cut(s)	697, 766
EcoT38I	GRGCYC	1 cut(s)	1013
ErhI	CCWWGG	2 cut(s)	697, 766
Esp3I	CGTCTC	1 cut(s)	58
FaeI	CATG	4 cut(s)	481, 661, 701, 865
FalI	AAGNNNNNCTT	2 cut(s)	399, 431
FaqI	GGGAC	1 cut(s)	872
FatI	CATG	4 cut(s)	477, 657, 697, 861
FauNDI	CATATG	1 cut(s)	566
Fnu4HI	GCNGC	6 cut(s)	6, 24, 27, 182, 463, 1046
FokI	GGATG	1 cut(s)	208
FriOI	GRGCYC	1 cut(s)	1013
Fsp4HI	GCNGC	6 cut(s)	6, 24, 27, 182, 463, 1046
FspBI	CTAG	2 cut(s)	369, 549
GluI	GCNGC	6 cut(s)	6, 24, 27, 182, 463, 1046
GsaI	CCCAGC	1 cut(s)	858
GsuI	CTGGAG	2 cut(s)	128, 953
HaeIII	GGCC	5 cut(s)	5, 188, 546, 691, 771
HapII	CCGG	1 cut(s)	467
Hin1II	CATG	4 cut(s)	481, 661, 701, 865
HinfI	GANTC	2 cut(s)	62, 641
HpaII	CCGG	1 cut(s)	467
Hpy166II	GTNNAC	1 cut(s)	413
Hpy188I	TCNGA	5 cut(s)	75, 208, 379, 646, 991
Hpy188III	TCNNGA	6 cut(s)	145, 236, 364, 683, 736, 925
Hpy8I	GTNNAC	1 cut(s)	413
HpyAV	CCTTC	3 cut(s)	51, 310, 339
HpyCH4III	ACNGT	3 cut(s)	229, 500, 838
HpyCH4IV	ACGT	2 cut(s)	51, 753
HpyCH4V	TGCA	8 cut(s)	184, 225, 670, 784, 789, 794, 822, 841
HpyF10VI	GCNNNNNNNGC	3 cut(s)	11, 20, 148
HpyF3I	CTNAG	7 cut(s)	114, 177, 207, 390, 579, 587, 906
HpySE526I	ACGT	2 cut(s)	51, 753
Hsp92II	CATG	4 cut(s)	481, 661, 701, 865
Kzo9I	GATC	2 cut(s)	94, 874
LmnI	GCTCC	2 cut(s)	147, 934
Lsp1109I	GCAGC	3 cut(s)	38, 168, 449
LweI	GCATC	1 cut(s)	138
MaeI	CTAG	2 cut(s)	369, 549
MaeII	ACGT	2 cut(s)	51, 753
MaeIII	GTNAC	4 cut(s)	152, 341, 500, 560
MalI	GATC	2 cut(s)	96, 876
MboI	GATC	2 cut(s)	94, 874
MboII	GAAGA	7 cut(s)	9, 195, 226, 366, 551, 989, 1046
MfeI	CAATTG	1 cut(s)	774
MflI	RGATCY	1 cut(s)	874
MhlI	GDGCHC	1 cut(s)	1013
MlyI	GAGTC	1 cut(s)	650
MseI	TTAA	5 cut(s)	132, 359, 491, 513, 1054
MslI	CAYNNNNRTG	2 cut(s)	426, 789
MspA1I	CMGCKG	1 cut(s)	181
MspI	CCGG	1 cut(s)	467
MspR9I	CCNGG	2 cut(s)	167, 467
MunI	CAATTG	1 cut(s)	774
MvaI	CCWGG	1 cut(s)	167
MwoI	GCNNNNNNNGC	3 cut(s)	11, 20, 148
NciI	CCSGG	1 cut(s)	467
NcoI	CCATGG	1 cut(s)	697
NdeI	CATATG	1 cut(s)	566
NdeII	GATC	2 cut(s)	94, 874
NlaIII	CATG	4 cut(s)	481, 661, 701, 865
NlaIV	GGNNCC	1 cut(s)	651
NmeAIII	GCCGAG	1 cut(s)	35
NmuCI	GTSAC	1 cut(s)	152
NspI	RCATGY	1 cut(s)	865
PciI	ACATGT	1 cut(s)	861
PcsI	WCGNNNNNNNCGW	1 cut(s)	907
PfeI	GAWTC	1 cut(s)	62
PflFI	GACNNNGTC	1 cut(s)	242
PflMI	CCANNNNNTGG	1 cut(s)	931
PkrI	GCNGC	6 cut(s)	7, 25, 28, 183, 464, 1047
PleI	GAGTC	1 cut(s)	649
PpsI	GAGTC	1 cut(s)	649
PscI	ACATGT	1 cut(s)	861
Psp124BI	GAGCTC	1 cut(s)	1013
Psp6I	CCWGG	1 cut(s)	165
PspFI	CCCAGC	1 cut(s)	854
PspGI	CCWGG	1 cut(s)	165
PspN4I	GGNNCC	1 cut(s)	651
PspPI	GGNCC	4 cut(s)	410, 545, 770, 922
PstI	CTGCAG	1 cut(s)	186
PstNI	CAGNNNCTG	1 cut(s)	931
PsuI	RGATCY	1 cut(s)	874
PsyI	GACNNNGTC	1 cut(s)	242
PvuII	CAGCTG	1 cut(s)	181
RsaI	GTAC	3 cut(s)	101, 107, 450
RsaNI	GTAC	3 cut(s)	100, 106, 449
RseI	CAYNNNNRTG	2 cut(s)	426, 789
SacI	GAGCTC	1 cut(s)	1013
SaqAI	TTAA	5 cut(s)	132, 359, 491, 513, 1054
SatI	GCNGC	6 cut(s)	6, 24, 27, 182, 463, 1046
Sau3AI	GATC	2 cut(s)	94, 874
Sau96I	GGNCC	4 cut(s)	410, 545, 770, 922
ScaI	AGTACT	1 cut(s)	107
SchI	GAGTC	1 cut(s)	650
ScrFI	CCNGG	2 cut(s)	167, 467
SduI	GDGCHC	1 cut(s)	1013
SfaNI	GCATC	1 cut(s)	138
SfcI	CTRYAG	1 cut(s)	182
SinI	GGWCC	2 cut(s)	410, 922
SmiMI	CAYNNNNRTG	2 cut(s)	426, 789
SmlI	CTYRAG	2 cut(s)	122, 452
SmoI	CTYRAG	2 cut(s)	122, 452
SpeI	ACTAGT	1 cut(s)	368
SsiI	CCGC	7 cut(s)	6, 12, 21, 24, 59, 333, 1043
SspMI	CTAG	2 cut(s)	369, 549
SstI	GAGCTC	1 cut(s)	1013
StyD4I	CCNGG	2 cut(s)	165, 465
StyI	CCWWGG	2 cut(s)	697, 766
TaaI	ACNGT	3 cut(s)	229, 500, 838
TaiI	ACGT	2 cut(s)	54, 756
TaqI	TCGA	4 cut(s)	93, 251, 314, 495
TaqII	GACCGA	1 cut(s)	891
TatI	WGTACW	2 cut(s)	99, 105
TauI	GCSGC	2 cut(s)	8, 26
TfiI	GAWTC	1 cut(s)	62
Tru1I	TTAA	5 cut(s)	132, 359, 491, 513, 1054
Tru9I	TTAA	5 cut(s)	132, 359, 491, 513, 1054
TscAI	CASTG	3 cut(s)	232, 796, 936
TseFI	GTSAC	1 cut(s)	152
TseI	GCWGC	4 cut(s)	26, 181, 462, 1045
Tsp45I	GTSAC	1 cut(s)	152
TspDTI	ATGAA	3 cut(s)	594, 818, 984
TspGWI	ACGGA	1 cut(s)	716
TspRI	CASTG	3 cut(s)	232, 796, 936
Tth111I	GACNNNGTC	1 cut(s)	242
Van91I	CCANNNNNTGG	1 cut(s)	931
VpaK11BI	GGWCC	2 cut(s)	410, 922
XagI	CCTNNNNNAGG	1 cut(s)	623
XapI	RAATTY	3 cut(s)	554, 846, 1015
XceI	RCATGY	1 cut(s)	865
XspI	CTAG	2 cut(s)	369, 549
ZrmI	AGTACT	1 cut(s)	107

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.