pycom06g08390

Subunit of clathrin-associated adaptor protein complex that plays a role in protein sorting in the late-Golgi trans-Golgi network (TGN) and or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
pyrus_communis
Chr6
OG0006717
Physical Location & Seq
Reverse (-)
13499855 .. 13503880
4026 bp
Loading structure...
UTR
Exon/CDS
Intron
pycom06g08390.9

Sequence Viewer

Length: 1569 bp
ATGAGCGGGCACGACTCCAAGTACTTCTCCACCACCAAGAAGGGCGAAATCCCTGAGCTCAAAGAGGAGCTCAATTCTCAATACAAGGATAAGAGAAAAGATGCGGTCAAGAAGGTGATCGCCGCAATGACTGTTGGGAAGGATGTTTCGTCACTTTTCACAGATGTAGTGAATTGCATGCAAACAGAAAACTTGGAGCTGAAGAAGCTTGTCTATTTGTATCTGATAAATTATGCTAAAAGCCAGCCTGATCTAGCAATACTTGCGGTGAATACATTTGTCAAGGATTCACAGGACCCAAATCCTTTGATTCGTGCTTTAGCCGTCCGGACAATGGGTTGCATTCGTGTTGATAAAATTACAGAATATCTATGTGATCCCCTTCAGAGATGTCTCAAGGATGATGATCGTTATGTGCGGAAGACAGCAGCCATATGTGTGGCCAAACTTTATGACATAAATGCAGAGTTAGTTGAGGATAGGGGTTTTCTGGAATCCCTCAAGGATTTGATATCTGATAATAATCCTATGGTTGTAGCAAATGCTGTGGCTGCTTTAGCCGAAATTCAAGAGAATAGTAATAGACCCATCTTTGAGATCACTAGTCACACTCTGTCAAAGCTCCTTACCGCCTTAAATGAATGTACAGAGTGGGGTCAAGTTTTCATATTGGATGCTCTTTCTAAATACAAGGCAGCAGACGCTCGTGAAGCTGAAAATATAGTAGAGCGAGTTACACCACGATTACAACATGCTAACTGTGCGGTTGTACTTTCAGCTGTTAAGATGATCCTCCAACAAATGGAACTTATAACTAGTACTGATGTCGTCAGAAATCTTTGCAAAAAGATGGCTCCTCCACTCGTGACACTACTATCTGCTGAGCCTGAGATACAATATGTTGCATTGAGAAACATCAACCTTATAGTGCAGAGACGACCCACAATCCTCGCTCATGAAATTAAGGTGTTCTTCTGCAAGTACAATGATCCAATTTATGTAAAGATGGAAAAGTTAGAAATCATGATAAAGCTTGCTTCAGACCGAAATATAGACCAGGTTTTGTTGGAGTTTAAAGAGTATGCTACCGAAGTAGATGTGGATTTTGTCCGAAAAGCTGTCCGTGCCATTGGTCGCTGTGCCATCAAATTAGAAAGAGCAGCTGAGCGGTGCATTACTGTTTTACTGGAGCTTATTAAGATCAAAGTAAATTATGTAGTTCAAGAGGCCATTATTGTCATCAAAGATATATTTAGAAGATATCCAAATACCTATGAGTCCATTATTGCAACTCTGTGTGAAAGCCTTGACACTTTAGATGAACCAGAAGCCAAGGCATCCATGATCTGGATAATTGGTGAATATGCGGAACGAATTGACAATGCTGATGAGCTACTTGAAAGTTTTCTGGAAAGTTTCCCTGAAGAGCCTGCTCATGTCCAATTGCAATTGCTGACTGCAACTGTTAAACTCTTTCTTAAGAAGCCAACTGAAGGACCACAGCAGATGATACAGGTTGTTTTAAATAATGCTACTGTGGAAACAGACAATCCTGATCTGCTTAAGTGA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
GO:0005575 GO:0005623 GO:0005886 GO:0005911 GO:0009506 GO:0016020 GO:0030054 GO:0044464 GO:0055044 GO:0071944
KEGG Pathways
Metabolic & Signaling
ko04142 map04142
Pfam Domains
Protein Families
Adaptin_N Alpha_adaptinC2 B2-adapt-app_C

Protein Analysis

523

Amino Acids

59.21

Weight (kDa)

5.38

Isoelectric Point (pI)

32.84

Instability Index
Protein Domains (Pfam)
No Pfam domains detected for this protein.
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
Loading...
Style Settings
Image
Tree File
Tip: Beautify your tree with professional tools

Download the Full Tree (.nwk) file, then upload it to any of the following tools to customize colors, fonts, annotations, clades, and branch support.

Publication-ready
iTOL Interactive Tree Of Life · Most popular EvolView Flexible annotations MEGA Desktop phylogenetics suite FigTree Desktop tree editor

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AanI TTATAA 1 cut(s) 812
AccB7I CCANNNNNTGG 2 cut(s) 802, 1347
AccBSI CCGCTC 2 cut(s) 6, 1168
AccIII TCCGGA 1 cut(s) 327
AciI CCGC 9 cut(s) 6, 104, 123, 266, 418, 630, 764, 1168, 1367
AclWI GGATC 3 cut(s) 371, 784, 983
AcoI YGGCCR 1 cut(s) 441
AcsI RAATTY 1 cut(s) 564
AcuI CTGAAG 5 cut(s) 221, 368, 1023, 1443, 1512
AfaI GTAC 5 cut(s) 23, 646, 771, 820, 983
AfiI CCNNNNNNNGG 4 cut(s) 334, 802, 1347, 1493
AflII CTTAAG 2 cut(s) 1478, 1562
AgsI TTSAA 3 cut(s) 569, 1223, 1400
AhlI ACTAGT 2 cut(s) 602, 815
AjnI CCWGG 1 cut(s) 1056
Alw21I GWGCWC 2 cut(s) 60, 72
Alw26I GTCTC 2 cut(s) 398, 928
AlwI GGATC 3 cut(s) 371, 784, 983
Aor13HI TCCGGA 1 cut(s) 327
AoxI GGCC 2 cut(s) 441, 1227
ApeKI GCWGC 4 cut(s) 428, 551, 695, 1160
ApoI RAATTY 1 cut(s) 564
Asp700I GAANNNNTTC 1 cut(s) 1404
AspS9I GGNCC 2 cut(s) 295, 1496
AsuHPI GGTGA 3 cut(s) 127, 280, 1370
AvaII GGWCC 2 cut(s) 295, 1496
BaeGI GKGCMC 1 cut(s) 12
BalI TGGCCA 1 cut(s) 443
BanII GRGCYC 2 cut(s) 60, 72
BauI CACGAG 2 cut(s) 705, 863
BbsI GAAGAC 1 cut(s) 428
Bbv12I GWGCWC 2 cut(s) 60, 72
BbvI GCAGC 4 cut(s) 440, 538, 707, 1172
BccI CCATC 4 cut(s) 596, 844, 1000, 1151
BceAI ACGGC 1 cut(s) 308
BciT130I CCWGG 1 cut(s) 1058
BcoDI GTCTC 2 cut(s) 398, 928
BcuI ACTAGT 2 cut(s) 602, 815
BfaI CTAG 3 cut(s) 254, 603, 816
BfrI CTTAAG 2 cut(s) 1478, 1562
BisI GCNGC 5 cut(s) 123, 429, 552, 696, 1161
BlpI GCTNAGC 2 cut(s) 882, 1164
BlsI GCNGC 5 cut(s) 124, 430, 553, 697, 1162
BmcAI AGTACT 2 cut(s) 23, 820
Bme1390I CCNGG 1 cut(s) 1058
Bme18I GGWCC 2 cut(s) 295, 1496
BmgT120I GGNCC 2 cut(s) 295, 1496
BmiI GGNNCC 2 cut(s) 297, 855
BmrFI CCNGG 1 cut(s) 1058
BmsI GCATC 3 cut(s) 91, 664, 1346
BpiI GAAGAC 1 cut(s) 428
BpmI CTGGAG 1 cut(s) 1208
Bpu10I CCTNAGC 1 cut(s) 54
Bpu1102I GCTNAGC 2 cut(s) 882, 1164
BpuEI CTTGAG 2 cut(s) 380, 485
BsaBI GATNNNNATC 2 cut(s) 405, 522
BsaJI CCNNGG 1 cut(s) 1332
BsaWI WCCGGW 1 cut(s) 327
Bsc4I CCNNNNNNNGG 4 cut(s) 334, 802, 1347, 1493
Bse1I ACTGG 1 cut(s) 1191
Bse3DI GCAATG 1 cut(s) 132
Bse8I GATNNNNATC 2 cut(s) 405, 522
BseAI TCCGGA 1 cut(s) 327
BseBI CCWGG 1 cut(s) 1058
BseDI CCNNGG 1 cut(s) 1332
BseGI GGATG 4 cut(s) 148, 406, 679, 1337
BseJI GATNNNNATC 2 cut(s) 405, 522
BseLI CCNNNNNNNGG 4 cut(s) 334, 802, 1347, 1493
BseMI GCAATG 1 cut(s) 132
BseMII CTCAG 4 cut(s) 45, 873, 879, 1155
BseNI ACTGG 1 cut(s) 1191
BseRI GAGGAG 2 cut(s) 80, 846
BseSI GKGCMC 1 cut(s) 12
BseXI GCAGC 4 cut(s) 440, 538, 707, 1172
BsgI GTGCAG 1 cut(s) 950
BshFI GGCC 2 cut(s) 443, 1229
BsiHKAI GWGCWC 2 cut(s) 60, 72
BsiSI CCGG 1 cut(s) 328
BslI CCNNNNNNNGG 4 cut(s) 334, 802, 1347, 1493
BsmAI GTCTC 2 cut(s) 398, 928
BsmBI CGTCTC 1 cut(s) 928
BsmI GAATGC 1 cut(s) 342
BsnI GGCC 2 cut(s) 443, 1229
Bsp1286I GDGCHC 3 cut(s) 12, 60, 72
Bsp13I TCCGGA 1 cut(s) 327
Bsp1407I TGTACA 1 cut(s) 644
Bsp1720I GCTNAGC 2 cut(s) 882, 1164
BspACI CCGC 9 cut(s) 6, 104, 123, 266, 418, 630, 764, 1168, 1367
BspANI GGCC 2 cut(s) 443, 1229
BspCNI CTCAG 4 cut(s) 46, 874, 880, 1156
BspEI TCCGGA 1 cut(s) 327
BspHI TCATGA 2 cut(s) 955, 1023
BspLI GGNNCC 2 cut(s) 297, 855
BspPI GGATC 3 cut(s) 371, 784, 983
BspQI GCTCTTC 1 cut(s) 1419
BspTI CTTAAG 2 cut(s) 1478, 1562
BsrBI CCGCTC 2 cut(s) 6, 1168
BsrDI GCAATG 1 cut(s) 132
BsrGI TGTACA 1 cut(s) 644
BsrI ACTGG 1 cut(s) 1191
BssECI CCNNGG 1 cut(s) 1332
BssSI CACGAG 2 cut(s) 705, 863
BssT1I CCWWGG 1 cut(s) 1332
Bst2BI CACGAG 2 cut(s) 705, 863
Bst2UI CCWGG 1 cut(s) 1058
Bst4CI ACNGT 5 cut(s) 133, 761, 1180, 1465, 1537
Bst6I CTCTTC 1 cut(s) 1419
BstAFI CTTAAG 2 cut(s) 1478, 1562
BstAPI GCANNNNNTGC 1 cut(s) 263
BstAUI TGTACA 1 cut(s) 644
BstC8I GCNNGC 5 cut(s) 8, 179, 245, 1035, 1431
BstDEI CTNAG 4 cut(s) 54, 882, 888, 1164
BstF5I GGATG 4 cut(s) 148, 406, 679, 1337
BstMAI GTCTC 2 cut(s) 398, 928
BstMWI GCNNNNNNNGC 8 cut(s) 205, 263, 551, 557, 701, 710, 761, 1124
BstNI CCWGG 1 cut(s) 1058
BstNSI RCATGY 2 cut(s) 181, 755
BstSCI CCNGG 1 cut(s) 1056
BstSLI GKGCMC 1 cut(s) 12
BstV1I GCAGC 4 cut(s) 440, 538, 707, 1172
BstV2I GAAGAC 1 cut(s) 428
BstXI CCANNNNNNTGG 1 cut(s) 439
BsuRI GGCC 2 cut(s) 443, 1229
BtsCI GGATG 4 cut(s) 148, 406, 679, 1337
Cac8I GCNNGC 5 cut(s) 8, 179, 245, 1035, 1431
CciI TCATGA 2 cut(s) 955, 1023
Cfr13I GGNCC 2 cut(s) 295, 1496
CseI GACGC 1 cut(s) 710
CsiI ACCWGGT 1 cut(s) 1056
Csp6I GTAC 5 cut(s) 22, 645, 770, 819, 982
CspCI CAANNNNNGTGG 2 cut(s) 528, 563
CviAII CATG 6 cut(s) 178, 752, 956, 1024, 1342, 1436
CviQI GTAC 5 cut(s) 22, 645, 770, 819, 982
DdeI CTNAG 4 cut(s) 54, 882, 888, 1164
DraI TTTAAA 2 cut(s) 1075, 1524
EaeI YGGCCR 1 cut(s) 441
Eam1104I CTCTTC 1 cut(s) 1419
EarI CTCTTC 1 cut(s) 1419
Ecl136II GAGCTC 2 cut(s) 58, 70
Eco130I CCWWGG 1 cut(s) 1332
Eco24I GRGCYC 2 cut(s) 60, 72
Eco32I GATATC 2 cut(s) 513, 1262
Eco47I GGWCC 2 cut(s) 295, 1496
Eco53kI GAGCTC 2 cut(s) 58, 70
Eco57I CTGAAG 5 cut(s) 221, 368, 1023, 1443, 1512
EcoICRI GAGCTC 2 cut(s) 58, 70
EcoO109I RGGNCCY 1 cut(s) 295
EcoRII CCWGG 1 cut(s) 1056
EcoRV GATATC 2 cut(s) 513, 1262
EcoT14I CCWWGG 1 cut(s) 1332
EcoT38I GRGCYC 2 cut(s) 60, 72
ErhI CCWWGG 1 cut(s) 1332
Esp3I CGTCTC 1 cut(s) 928
FaeI CATG 6 cut(s) 181, 755, 959, 1027, 1345, 1439
FalI AAGNNNNNCTT 2 cut(s) 956, 988
FatI CATG 6 cut(s) 177, 751, 955, 1023, 1341, 1435
FauNDI CATATG 1 cut(s) 434
Fnu4HI GCNGC 5 cut(s) 123, 429, 552, 696, 1161
FokI GGATG 4 cut(s) 155, 413, 686, 1324
FriOI GRGCYC 2 cut(s) 60, 72
Fsp4HI GCNGC 5 cut(s) 123, 429, 552, 696, 1161
FspBI CTAG 3 cut(s) 254, 603, 816
GluI GCNGC 5 cut(s) 123, 429, 552, 696, 1161
GsuI CTGGAG 1 cut(s) 1208
HaeIII GGCC 2 cut(s) 443, 1229
HapII CCGG 1 cut(s) 328
HgaI GACGC 1 cut(s) 710
Hin1II CATG 6 cut(s) 181, 755, 959, 1027, 1345, 1439
HindIII AAGCTT 2 cut(s) 206, 1031
HinfI GANTC 5 cut(s) 14, 287, 310, 494, 1277
HpaII CCGG 1 cut(s) 328
HphI GGTGA 3 cut(s) 127, 280, 1370
Hpy188I TCNGA 6 cut(s) 225, 387, 517, 833, 1042, 1112
HpyAV CCTTC 5 cut(s) 34, 106, 133, 392, 1487
HpyCH4III ACNGT 5 cut(s) 133, 761, 1180, 1465, 1537
HpyF10VI GCNNNNNNNGC 8 cut(s) 205, 263, 551, 557, 701, 710, 761, 1124
HpyF3I CTNAG 4 cut(s) 54, 882, 888, 1164
Hsp92II CATG 6 cut(s) 181, 755, 959, 1027, 1345, 1439
Kpn2I TCCGGA 1 cut(s) 327
LguI GCTCTTC 1 cut(s) 1419
LmnI GCTCC 5 cut(s) 67, 196, 627, 859, 1189
Lsp1109I GCAGC 4 cut(s) 440, 538, 707, 1172
LweI GCATC 3 cut(s) 91, 664, 1346
MabI ACCWGGT 1 cut(s) 1056
MaeI CTAG 3 cut(s) 254, 603, 816
MaeIII GTNAC 4 cut(s) 150, 605, 733, 865
MbiI CCGCTC 2 cut(s) 6, 1168
MboII GAAGA 5 cut(s) 214, 433, 964, 1269, 1436
MfeI CAATTG 2 cut(s) 1442, 1448
MhlI GDGCHC 3 cut(s) 12, 60, 72
MlsI TGGCCA 1 cut(s) 443
MluNI TGGCCA 1 cut(s) 443
MlyI GAGTC 2 cut(s) 8, 1286
MmeI TCCRAC 2 cut(s) 820, 1047
MnlI CCTC 7 cut(s) 58, 469, 509, 803, 867, 959, 1219
Mox20I TGGCCA 1 cut(s) 443
MroI TCCGGA 1 cut(s) 327
MroXI GAANNNNTTC 1 cut(s) 1404
MscI TGGCCA 1 cut(s) 443
MseI TTAA 9 cut(s) 635, 783, 963, 1074, 1197, 1467, 1479, 1523, 1563
MslI CAYNNNNRTG 1 cut(s) 437
Msp20I TGGCCA 1 cut(s) 443
MspA1I CMGCKG 2 cut(s) 779, 1163
MspCI CTTAAG 2 cut(s) 1478, 1562
MspI CCGG 1 cut(s) 328
MspR9I CCNGG 1 cut(s) 1058
MunI CAATTG 2 cut(s) 1442, 1448
Mva1269I GAATGC 1 cut(s) 342
MvaI CCWGG 1 cut(s) 1058
MwoI GCNNNNNNNGC 8 cut(s) 205, 263, 551, 557, 701, 710, 761, 1124
NdeI CATATG 1 cut(s) 434
NlaIII CATG 6 cut(s) 181, 755, 959, 1027, 1345, 1439
NlaIV GGNNCC 2 cut(s) 297, 855
NmuCI GTSAC 3 cut(s) 150, 605, 865
NspI RCATGY 2 cut(s) 181, 755
PaeI GCATGC 1 cut(s) 181
PagI TCATGA 2 cut(s) 955, 1023
PciSI GCTCTTC 1 cut(s) 1419
PctI GAATGC 1 cut(s) 342
PdmI GAANNNNTTC 1 cut(s) 1404
PfeI GAWTC 3 cut(s) 287, 310, 494
PflMI CCANNNNNTGG 2 cut(s) 802, 1347
PkrI GCNGC 5 cut(s) 124, 430, 553, 697, 1162
PleI GAGTC 2 cut(s) 8, 1285
PpsI GAGTC 2 cut(s) 8, 1285
PpuMI RGGWCCY 1 cut(s) 295
PsiI TTATAA 1 cut(s) 812
Psp124BI GAGCTC 2 cut(s) 60, 72
Psp5II RGGWCCY 1 cut(s) 295
Psp6I CCWGG 1 cut(s) 1056
PspGI CCWGG 1 cut(s) 1056
PspN4I GGNNCC 2 cut(s) 297, 855
PspPI GGNCC 2 cut(s) 295, 1496
PspPPI RGGWCCY 1 cut(s) 295
PvuII CAGCTG 2 cut(s) 779, 1163
RsaI GTAC 5 cut(s) 23, 646, 771, 820, 983
RsaNI GTAC 5 cut(s) 22, 645, 770, 819, 982
RseI CAYNNNNRTG 1 cut(s) 437
SacI GAGCTC 2 cut(s) 60, 72
SapI GCTCTTC 1 cut(s) 1419
SaqAI TTAA 9 cut(s) 635, 783, 963, 1074, 1197, 1467, 1479, 1523, 1563
SatI GCNGC 5 cut(s) 123, 429, 552, 696, 1161
Sau96I GGNCC 2 cut(s) 295, 1496
ScaI AGTACT 2 cut(s) 23, 820
SchI GAGTC 2 cut(s) 8, 1286
ScrFI CCNGG 1 cut(s) 1058
SduI GDGCHC 3 cut(s) 12, 60, 72
SexAI ACCWGGT 1 cut(s) 1056
SfaNI GCATC 3 cut(s) 91, 664, 1346
SinI GGWCC 2 cut(s) 295, 1496
SmiMI CAYNNNNRTG 1 cut(s) 437
SmlI CTYRAG 4 cut(s) 395, 500, 1478, 1562
SmoI CTYRAG 4 cut(s) 395, 500, 1478, 1562
SpeI ACTAGT 2 cut(s) 602, 815
SphI GCATGC 1 cut(s) 181
SsiI CCGC 9 cut(s) 6, 104, 123, 266, 418, 630, 764, 1168, 1367
SspMI CTAG 3 cut(s) 254, 603, 816
SstI GAGCTC 2 cut(s) 60, 72
StyD4I CCNGG 1 cut(s) 1056
StyI CCWWGG 1 cut(s) 1332
TaaI ACNGT 5 cut(s) 133, 761, 1180, 1465, 1537
TaqII GACCGA 1 cut(s) 1059
TatI WGTACW 5 cut(s) 21, 644, 769, 818, 981
TauI GCSGC 1 cut(s) 125
TfiI GAWTC 3 cut(s) 287, 310, 494
Tru1I TTAA 9 cut(s) 635, 783, 963, 1074, 1197, 1467, 1479, 1523, 1563
Tru9I TTAA 9 cut(s) 635, 783, 963, 1074, 1197, 1467, 1479, 1523, 1563
TseFI GTSAC 3 cut(s) 150, 605, 865
TseI GCWGC 4 cut(s) 428, 551, 695, 1160
Tsp45I GTSAC 3 cut(s) 150, 605, 865
TspDTI ATGAA 4 cut(s) 654, 655, 972, 1335
TspGWI ACGGA 1 cut(s) 1112
Van91I CCANNNNNTGG 2 cut(s) 802, 1347
Vha464I CTTAAG 2 cut(s) 1478, 1562
VpaK11BI GGWCC 2 cut(s) 295, 1496
XapI RAATTY 1 cut(s) 564
XceI RCATGY 2 cut(s) 181, 755
XmnI GAANNNNTTC 1 cut(s) 1404
XspI CTAG 3 cut(s) 254, 603, 816
ZrmI AGTACT 2 cut(s) 23, 820
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.