pycom15g10540

transcriptional co-repressor

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
pyrus_communis
Chr15
OG0008825
Physical Location & Seq
Reverse (-)
7001232 .. 7004219
2988 bp
Loading structure...
UTR
Exon/CDS
Intron
N/A

Sequence Viewer

Length: 1167 bp
ATGGGTGTGATTATCATGTCCCGTTTCATTTTTGTGCACCCGAGTCTCCTTGAGATGGTTCTTTTGTCATCAAGATTTAGAAAGTGGAAAGATGATCAAGGAAAAGAGTTGAGGAATAGAGAAAGAAAGCTTCTGCTCCAAAGAGAACATCCACAACTCCTTAAGCCTCTGATGATGTCTGGTGCTGATGCTGCTCTTTCATCACTCTCAGTTCAGTTGACGGATATGGATCAATTTACAGACGATGCAGAAGATGATGAACTTCTTGATGATGCACAATCTACAGGGTTCACATTTACGGAAAAAAACTCTGCCAGAGCAAGTGCAAGCAAGGTTGTGAGTTGCCACATCTCATCAGATGGAAAAGTTCTTGCTAGTGGTGGCCTTGATAAGAAGGCCGTACTGTGGTACACAGACAGTTTAACGCCAAAAGCTGTTCTCGGAGAACATTCATTGTTGATAGCTGATGTTCATTTCAGCCCGAGCATGCCACGTCTTGCAACATCTTCATTCGACAAAACTGTCAAGATCTGGGATGCTGACAATCCTGTTTCATTTTGCACCTTTATGGGACATTCTGCTCCTGTCCTGTCAGTAGATTTTCACCCAAACAATGATGACCTTATCTGTTCGTGTGATGCGAGTGGTGAGATACGGTACTGGAGAATTAACAATGGCTTCTGTGAAAGCGTGTTTAAGGGTGGTAAGAGGCAGGTGAGATTTCAACCCCGTCTTGGAAGATTTCTTGCTACAGCTGCAGAGAATGTTGTACATATACTGGATGTGGAGACACAAGCTTGTCGTCATTCATTACAGGGGCATACTAAGCCTATCCATTCTGTGTGCTGGGATCCTTCTGGTGAGTTTCTCGCATCTGTCAGTGATGACTCTGTTAGAGTTTGGGCACTTGGAGTAGGAGGGGAAGGCGAATGCGTTCATGAGTTGAGCTGCAACGGAAGTAAATTTCAATCGTGTGTTTTCCATCATACATATACTTCACTGCTTGTCATTGGCTGTTATCAGACACTGGAGTTATGGAACATGACAGAGAACAAGGTAATGACTCTACCAGCACATGAAGGACTCATTGCTTCTTTGGCAGTGTCAAATGTTACAGGTTTGATTGCTTCGGCTGGTCACGATAAGTTTGTCAAGATCTGGAAGTGA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
GO:0000003 GO:0001101 GO:0001558 GO:0001666 GO:0003002 GO:0003006 GO:0005975 GO:0005976 GO:0006355 GO:0006950 GO:0006974 GO:0006979 GO:0007275 GO:0007389 GO:0008150 GO:0008152 GO:0009414 GO:0009415 GO:0009605 GO:0009607 GO:0009611 GO:0009617 GO:0009620 GO:0009624 GO:0009628 GO:0009636 GO:0009719 GO:0009725 GO:0009733 GO:0009791 GO:0009798 GO:0009845 GO:0009888 GO:0009889 GO:0009890 GO:0009892 GO:0009909 GO:0009943 GO:0009944 GO:0009955 GO:0009987 GO:0010033 GO:0010035 GO:0010038 GO:0010073 GO:0010154 GO:0010191 GO:0010214 GO:0010243 GO:0010272 GO:0010393 GO:0010468 GO:0010556 GO:0010558 GO:0010605 GO:0010629 GO:0014070 GO:0019219 GO:0019222 GO:0022414 GO:0022603 GO:0022604 GO:0030307 GO:0031323 GO:0031324 GO:0031326 GO:0031327 GO:0032501 GO:0032502 GO:0032504 GO:0033554 GO:0036293 GO:0040008 GO:0042221 GO:0042493 GO:0043170 GO:0043207 GO:0044237 GO:0044238 GO:0045892 GO:0045927 GO:0045934 GO:0045995 GO:0046677 GO:0046898 GO:0048316 GO:0048359 GO:0048507 GO:0048509 GO:0048518 GO:0048519 GO:0048522 GO:0048523 GO:0048580 GO:0048608 GO:0048609 GO:0048638 GO:0048639 GO:0048731 GO:0048831 GO:0048856 GO:0050789 GO:0050793 GO:0050794 GO:0050896 GO:0051094 GO:0051128 GO:0051130 GO:0051171 GO:0051172 GO:0051239 GO:0051252 GO:0051253 GO:0051510 GO:0051512 GO:0051704 GO:0051707 GO:0051716 GO:0060255 GO:0060992 GO:0061458 GO:0065001 GO:0065007 GO:0070482 GO:0071216 GO:0071217 GO:0071496 GO:0071704 GO:0080001 GO:0080090 GO:0090351 GO:0097305 GO:1901654 GO:1901698 GO:1901700 GO:1902074 GO:1902183 GO:1902679 GO:1903506 GO:1903507 GO:2000024 GO:2000026 GO:2000112 GO:2000113 GO:2000241 GO:2001141
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
LisH WD40

Protein Analysis

389

Amino Acids

42.92

Weight (kDa)

6.05

Isoelectric Point (pI)

35.57

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
Beta-prop_CAF1B_HIR1 PF24105 88 - 182 2e-06 CAF1B/HIR1 beta-propeller domain
Beta-prop_TEP1_2nd PF25047 98 - 199 8.7e-07 TEP-1 second beta-propeller
Beta-prop_WDR5 PF25175 108 - 237 1.7e-22 WDR5 beta-propeller domain
Beta-prop_EML_2 PF23414 108 - 226 6.2e-12 Echinoderm microtubule-associated protein second beta-propeller
WD40_Gbeta PF25391 108 - 237 1.2e-08 G protein beta WD-40 repeat protein
WD40_Prp19 PF24814 108 - 334 9.2e-29 Prp19 WD40 domain
Beta-prop_WDR3_1st PF25173 109 - 223 3.9e-18 WDR3 first beta-propeller domain
Beta-prop_THOC3 PF25174 110 - 182 5.5e-12 THOC3 beta-propeller domain
WD40_WDHD1_1st PF24817 110 - 182 2.8e-07 WDHD1 first WD40 domain
Beta-prop_WDR3_2nd PF25172 111 - 181 2.1e-07 WDR3 second beta-propeller domain
Beta-prop_EML PF23409 114 - 226 2.2e-06 Echinoderm microtubule-associated protein first beta-propeller
WD40 PF00400 143 - 179 3.7e-06 WD domain, G-beta repeat
WD40_CDC20-Fz PF24807 147 - 228 1.4e-08 CDC20/Fizzy WD40 domain
Beta-prop_THOC3 PF25174 150 - 388 2.3e-33 THOC3 beta-propeller domain
WD40_WDHD1_1st PF24817 151 - 235 4.3e-11 WDHD1 first WD40 domain
Beta-prop_WDR3_2nd PF25172 157 - 302 4.5e-16 WDR3 second beta-propeller domain
Beta-prop_WDR90_POC16_2nd PF23393 162 - 225 5e-06 WDR90/POC16, second beta-propeller
WDR55 PF24796 194 - 354 1e-08 WDR55
Beta-prop_WDR3_1st PF25173 210 - 347 4.3e-15 WDR3 first beta-propeller domain
Beta-prop_WDR36-Utp21_2nd PF25168 211 - 305 6.7e-07 WDR36/Utp21 second beta-propeller domain
Beta-prop_WDR5 PF25175 238 - 387 4.4e-25 WDR5 beta-propeller domain
WD40_WDHD1_1st PF24817 240 - 317 3.2e-10 WDHD1 first WD40 domain
WD40_Gbeta PF25391 243 - 387 4.3e-09 G protein beta WD-40 repeat protein
Beta-prop_WDR36-Utp21_1st PF25171 248 - 376 5.6e-07 WDR36/Utp21 first beta-propeller
WD40_CDC20-Fz PF24807 249 - 387 1.1e-09 CDC20/Fizzy WD40 domain
WD40 PF00400 267 - 301 1.3e-09 WD domain, G-beta repeat
Beta-prop_WDR3_1st PF25173 298 - 387 7.2e-06 WDR3 first beta-propeller domain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AarI CACCTGC 1 cut(s) 703
AasI GACNNNNNNGTC 1 cut(s) 521
Acc36I ACCTGC 1 cut(s) 703
AclWI GGATC 3 cut(s) 237, 845, 858
AcsI RAATTY 1 cut(s) 962
AfaI GTAC 4 cut(s) 402, 410, 659, 771
AfiI CCNNNNNNNGG 3 cut(s) 55, 405, 734
AflII CTTAAG 1 cut(s) 161
AgsI TTSAA 2 cut(s) 725, 968
AjiI CACGTC 1 cut(s) 494
AluBI AGCT 6 cut(s) 130, 434, 464, 755, 797, 948
AluI AGCT 6 cut(s) 130, 434, 464, 755, 797, 948
Alw21I GWGCWC 1 cut(s) 39
Alw26I GTCTC 2 cut(s) 50, 782
Alw44I GTGCAC 1 cut(s) 35
AlwI GGATC 3 cut(s) 237, 845, 858
AlwNI CAGNNNCTG 1 cut(s) 1027
Ama87I CYCGRG 2 cut(s) 40, 481
AoxI GGCC 2 cut(s) 382, 396
ApaLI GTGCAC 1 cut(s) 35
ApeKI GCWGC 3 cut(s) 191, 755, 948
ApoI RAATTY 1 cut(s) 962
Asp700I GAANNNNTTC 1 cut(s) 933
AsuHPI GGTGA 4 cut(s) 596, 659, 727, 872
AvaI CYCGRG 2 cut(s) 40, 481
BaeGI GKGCMC 2 cut(s) 39, 907
BamHI GGATCC 1 cut(s) 850
Bbv12I GWGCWC 1 cut(s) 39
BbvI GCAGC 3 cut(s) 178, 742, 935
BccI CCATC 3 cut(s) 49, 353, 990
BceAI ACGGC 1 cut(s) 383
BclI TGATCA 1 cut(s) 94
BcoDI GTCTC 2 cut(s) 50, 782
BfaI CTAG 1 cut(s) 375
BfmI CTRYAG 3 cut(s) 282, 750, 756
BfrI CTTAAG 1 cut(s) 161
BfuAI ACCTGC 1 cut(s) 703
BglII AGATCT 2 cut(s) 528, 1155
BisI GCNGC 3 cut(s) 192, 756, 949
BlsI GCNGC 3 cut(s) 193, 757, 950
BmeT110I CYCGRG 2 cut(s) 40, 481
BmgBI CACGTC 1 cut(s) 494
BmiI GGNNCC 1 cut(s) 852
BmsI GCATC 6 cut(s) 178, 235, 262, 526, 628, 881
BpmI CTGGAG 2 cut(s) 682, 1049
BpuEI CTTGAG 1 cut(s) 71
BsaBI GATNNNNATC 1 cut(s) 228
Bsc4I CCNNNNNNNGG 3 cut(s) 55, 405, 734
Bse1I ACTGG 3 cut(s) 665, 783, 1032
Bse3DI GCAATG 1 cut(s) 1086
Bse8I GATNNNNATC 1 cut(s) 228
BseGI GGATG 3 cut(s) 148, 541, 787
BseJI GATNNNNATC 1 cut(s) 228
BseLI CCNNNNNNNGG 3 cut(s) 55, 405, 734
BseMI GCAATG 1 cut(s) 1086
BseMII CTCAG 1 cut(s) 222
BseNI ACTGG 3 cut(s) 665, 783, 1032
BseSI GKGCMC 2 cut(s) 39, 907
BseXI GCAGC 3 cut(s) 178, 742, 935
BseYI CCCAGC 1 cut(s) 846
BshFI GGCC 2 cut(s) 384, 398
BsiHKAI GWGCWC 1 cut(s) 39
BsiHKCI CYCGRG 2 cut(s) 40, 481
BslFI GGGAC 2 cut(s) 4, 585
BslI CCNNNNNNNGG 3 cut(s) 55, 405, 734
BsmAI GTCTC 2 cut(s) 50, 782
BsmFI GGGAC 2 cut(s) 4, 585
BsmI GAATGC 1 cut(s) 935
BsnI GGCC 2 cut(s) 384, 398
BsoBI CYCGRG 2 cut(s) 40, 481
Bsp1286I GDGCHC 2 cut(s) 39, 907
Bsp1407I TGTACA 1 cut(s) 769
Bsp143I GATC 5 cut(s) 94, 229, 528, 850, 1155
BspANI GGCC 2 cut(s) 384, 398
BspCNI CTCAG 1 cut(s) 221
BspHI TCATGA 1 cut(s) 937
BspLI GGNNCC 1 cut(s) 852
BspMAI CTGCAG 1 cut(s) 760
BspMI ACCTGC 1 cut(s) 703
BspPI GGATC 3 cut(s) 237, 845, 858
BspTI CTTAAG 1 cut(s) 161
BsrDI GCAATG 1 cut(s) 1086
BsrGI TGTACA 1 cut(s) 769
BsrI ACTGG 3 cut(s) 665, 783, 1032
BssMI GATC 5 cut(s) 94, 229, 528, 850, 1155
Bst4CI ACNGT 4 cut(s) 405, 419, 523, 657
BstAFI CTTAAG 1 cut(s) 161
BstAUI TGTACA 1 cut(s) 769
BstC8I GCNNGC 2 cut(s) 328, 488
BstDEI CTNAG 2 cut(s) 208, 825
BstF5I GGATG 3 cut(s) 148, 541, 787
BstKTI GATC 5 cut(s) 97, 232, 531, 853, 1158
BstMAI GTCTC 2 cut(s) 50, 782
BstMBI GATC 5 cut(s) 94, 229, 528, 850, 1155
BstMWI GCNNNNNNNGC 4 cut(s) 191, 755, 826, 1097
BstNSI RCATGY 1 cut(s) 490
BstSFI CTRYAG 3 cut(s) 282, 750, 756
BstSLI GKGCMC 2 cut(s) 39, 907
BstV1I GCAGC 3 cut(s) 178, 742, 935
BstX2I RGATCY 3 cut(s) 528, 850, 1155
BstYI RGATCY 3 cut(s) 528, 850, 1155
BsuRI GGCC 2 cut(s) 384, 398
BtrI CACGTC 1 cut(s) 494
BtsCI GGATG 3 cut(s) 148, 541, 787
BtsI GCAGTG 2 cut(s) 998, 1107
BtsIMutI CAGTG 4 cut(s) 886, 998, 1025, 1107
BveI ACCTGC 1 cut(s) 703
Cac8I GCNNGC 2 cut(s) 328, 488
CaiI CAGNNNCTG 1 cut(s) 1027
CciI TCATGA 1 cut(s) 937
Csp6I GTAC 4 cut(s) 401, 409, 658, 770
CviAII CATG 5 cut(s) 16, 487, 938, 1042, 1076
CviQI GTAC 4 cut(s) 401, 409, 658, 770
DdeI CTNAG 2 cut(s) 208, 825
DpnI GATC 5 cut(s) 96, 231, 530, 852, 1157
DpnII GATC 5 cut(s) 94, 229, 528, 850, 1155
DrdI GACNNNNNNGTC 1 cut(s) 521
DseDI GACNNNNNNGTC 1 cut(s) 521
Eco88I CYCGRG 2 cut(s) 40, 481
FaeI CATG 5 cut(s) 19, 490, 941, 1045, 1079
FaqI GGGAC 2 cut(s) 4, 585
FatI CATG 5 cut(s) 15, 486, 937, 1041, 1075
FbaI TGATCA 1 cut(s) 94
Fnu4HI GCNGC 3 cut(s) 192, 756, 949
FokI GGATG 3 cut(s) 135, 548, 794
Fsp4HI GCNGC 3 cut(s) 192, 756, 949
FspBI CTAG 1 cut(s) 375
GluI GCNGC 3 cut(s) 192, 756, 949
GsaI CCCAGC 1 cut(s) 850
GsuI CTGGAG 2 cut(s) 682, 1049
HaeIII GGCC 2 cut(s) 384, 398
Hin1II CATG 5 cut(s) 19, 490, 941, 1045, 1079
HincII GTYRAC 1 cut(s) 219
HindII GTYRAC 1 cut(s) 219
HindIII AAGCTT 2 cut(s) 128, 795
HinfI GANTC 4 cut(s) 43, 887, 1063, 1083
HphI GGTGA 4 cut(s) 596, 659, 727, 872
Hpy166II GTNNAC 4 cut(s) 37, 219, 291, 411
Hpy188I TCNGA 4 cut(s) 171, 358, 443, 1023
Hpy188III TCNNGA 7 cut(s) 72, 266, 526, 938, 1139, 1153, 1159
Hpy8I GTNNAC 4 cut(s) 37, 219, 291, 411
HpyAV CCTTC 4 cut(s) 388, 864, 917, 1073
HpyCH4III ACNGT 4 cut(s) 405, 419, 523, 657
HpyCH4IV ACGT 1 cut(s) 493
HpyCH4V TGCA 8 cut(s) 37, 248, 275, 326, 500, 561, 758, 951
HpyF10VI GCNNNNNNNGC 4 cut(s) 191, 755, 826, 1097
HpyF3I CTNAG 2 cut(s) 208, 825
HpySE526I ACGT 1 cut(s) 493
Hsp92II CATG 5 cut(s) 19, 490, 941, 1045, 1079
Ksp22I TGATCA 1 cut(s) 94
Kzo9I GATC 5 cut(s) 94, 229, 528, 850, 1155
LmnI GCTCC 2 cut(s) 141, 586
Lsp1109I GCAGC 3 cut(s) 178, 742, 935
LweI GCATC 6 cut(s) 178, 235, 262, 526, 628, 881
MaeI CTAG 1 cut(s) 375
MaeII ACGT 1 cut(s) 493
MaeIII GTNAC 2 cut(s) 1111, 1136
MalI GATC 5 cut(s) 96, 231, 530, 852, 1157
MboI GATC 5 cut(s) 94, 229, 528, 850, 1155
MboII GAAGA 3 cut(s) 263, 498, 750
MflI RGATCY 3 cut(s) 528, 850, 1155
MhlI GDGCHC 2 cut(s) 39, 907
MluCI AATT 3 cut(s) 233, 666, 962
MlyI GAGTC 4 cut(s) 52, 881, 1057, 1077
MnlI CCTC 4 cut(s) 105, 177, 702, 911
MroXI GAANNNNTTC 1 cut(s) 933
MseI TTAA 4 cut(s) 162, 422, 669, 696
MslI CAYNNNNRTG 2 cut(s) 32, 566
MspA1I CMGCKG 1 cut(s) 755
MspCI CTTAAG 1 cut(s) 161
Mva1269I GAATGC 1 cut(s) 935
MwoI GCNNNNNNNGC 4 cut(s) 191, 755, 826, 1097
NdeII GATC 5 cut(s) 94, 229, 528, 850, 1155
NlaIII CATG 5 cut(s) 19, 490, 941, 1045, 1079
NlaIV GGNNCC 1 cut(s) 852
NmuCI GTSAC 1 cut(s) 1136
NspI RCATGY 1 cut(s) 490
PaeI GCATGC 1 cut(s) 490
PagI TCATGA 1 cut(s) 937
PaqCI CACCTGC 1 cut(s) 703
PcsI WCGNNNNNNNCGW 1 cut(s) 638
PctI GAATGC 1 cut(s) 935
PdmI GAANNNNTTC 1 cut(s) 933
PkrI GCNGC 3 cut(s) 193, 757, 950
PleI GAGTC 4 cut(s) 51, 881, 1057, 1077
PpsI GAGTC 4 cut(s) 51, 881, 1057, 1077
PspFI CCCAGC 1 cut(s) 846
PspN4I GGNNCC 1 cut(s) 852
PstI CTGCAG 1 cut(s) 760
PstNI CAGNNNCTG 1 cut(s) 1027
PsuI RGATCY 3 cut(s) 528, 850, 1155
PvuII CAGCTG 1 cut(s) 755
RsaI GTAC 4 cut(s) 402, 410, 659, 771
RsaNI GTAC 4 cut(s) 401, 409, 658, 770
RseI CAYNNNNRTG 2 cut(s) 32, 566
SaqAI TTAA 4 cut(s) 162, 422, 669, 696
SatI GCNGC 3 cut(s) 192, 756, 949
Sau3AI GATC 5 cut(s) 94, 229, 528, 850, 1155
SchI GAGTC 4 cut(s) 52, 881, 1057, 1077
SduI GDGCHC 2 cut(s) 39, 907
SfaNI GCATC 6 cut(s) 178, 235, 262, 526, 628, 881
SfcI CTRYAG 3 cut(s) 282, 750, 756
SmiMI CAYNNNNRTG 2 cut(s) 32, 566
SmlI CTYRAG 2 cut(s) 50, 161
SmoI CTYRAG 2 cut(s) 50, 161
SphI GCATGC 1 cut(s) 490
Sse9I AATT 3 cut(s) 233, 666, 962
SspMI CTAG 1 cut(s) 375
TaaI ACNGT 4 cut(s) 405, 419, 523, 657
TaiI ACGT 1 cut(s) 496
TaqI TCGA 1 cut(s) 513
TasI AATT 3 cut(s) 233, 666, 962
TatI WGTACW 1 cut(s) 769
Tru1I TTAA 4 cut(s) 162, 422, 669, 696
Tru9I TTAA 4 cut(s) 162, 422, 669, 696
TscAI CASTG 4 cut(s) 886, 1005, 1032, 1107
TseFI GTSAC 1 cut(s) 1136
TseI GCWGC 3 cut(s) 191, 755, 948
Tsp45I GTSAC 1 cut(s) 1136
TspGWI ACGGA 3 cut(s) 236, 314, 969
TspRI CASTG 4 cut(s) 886, 1005, 1032, 1107
Vha464I CTTAAG 1 cut(s) 161
VneI GTGCAC 1 cut(s) 35
XapI RAATTY 1 cut(s) 962
XceI RCATGY 1 cut(s) 490
XmnI GAANNNNTTC 1 cut(s) 933
XspI CTAG 1 cut(s) 375
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.