The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.
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| Species | Orthologous Gene IDs |
|---|---|
| arabidopsis_thaliana | AT1G11020 |
| fragaria_vesca | FvH4_1g03950 FvH4_1g03950 FvH4_1g03950 FvH4_6g51470 |
| malus_domestica | MD02G1038000.v1.1 MD15G1178300.v1.1 |
| prunus_persica | Prupe.7G237300_v2.0.a1 Prupe.7G237300_v2.0.a1 Prupe.7G237300_v2.0.a1 Prupe.7G237300_v2.0.a1 |
| pyrus_communis | pycom02g03110 pycom15g16000 |
| rosa_chinensis | RchiOBHm_Chr2g0089431 |
| rosa_laevigata | RLG00000016027 |
| rosa_multiflora | Rmu_sc0000197.1_g000010 Rmu_sc0000197.1_g000012 |
| rosa_roxburghii | Rroxscaffold_2G00151940 Rroxscaffold_5G00344790 |
| rosa_rugosa | Rorug02G0000800 Rorug02G0000800 |
| rosa_samantha | Rh2AG045900 Rh2BG044400 Rh2CG046300 Rh2DG045800 |
| rosa_wichuraiana | Rw2G003670 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AccB1I | GGYRCC | 1 cut(s) | 224 |
| AccII | CGCG | 1 cut(s) | 754 |
| AciI | CCGC | 1 cut(s) | 618 |
| AclWI | GGATC | 5 cut(s) | 363, 467, 647, 711, 731 |
| AcsI | RAATTY | 1 cut(s) | 334 |
| AcuI | CTGAAG | 1 cut(s) | 313 |
| AfaI | GTAC | 1 cut(s) | 405 |
| AhdI | GACNNNNNGTC | 2 cut(s) | 94, 136 |
| AjnI | CCWGG | 2 cut(s) | 84, 558 |
| AluBI | AGCT | 4 cut(s) | 19, 108, 284, 602 |
| AluI | AGCT | 4 cut(s) | 19, 108, 284, 602 |
| Alw26I | GTCTC | 5 cut(s) | 39, 45, 173, 257, 643 |
| AlwI | GGATC | 5 cut(s) | 363, 467, 647, 711, 731 |
| Ama87I | CYCGRG | 1 cut(s) | 109 |
| AoxI | GGCC | 2 cut(s) | 324, 408 |
| ApeKI | GCWGC | 4 cut(s) | 16, 284, 421, 489 |
| ApoI | RAATTY | 1 cut(s) | 334 |
| AspLEI | GCGC | 3 cut(s) | 267, 754, 756 |
| AspS9I | GGNCC | 2 cut(s) | 246, 324 |
| AsuHPI | GGTGA | 2 cut(s) | 44, 198 |
| AvaI | CYCGRG | 1 cut(s) | 109 |
| AvaII | GGWCC | 1 cut(s) | 246 |
| BanI | GGYRCC | 1 cut(s) | 224 |
| BanII | GRGCYC | 1 cut(s) | 441 |
| BbsI | GAAGAC | 1 cut(s) | 135 |
| BbvI | GCAGC | 4 cut(s) | 28, 271, 408, 476 |
| BccI | CCATC | 2 cut(s) | 314, 341 |
| BcgI | CGANNNNNNTGC | 4 cut(s) | 151, 161, 185, 195 |
| BciT130I | CCWGG | 2 cut(s) | 86, 560 |
| BcoDI | GTCTC | 5 cut(s) | 39, 45, 173, 257, 643 |
| BfaI | CTAG | 1 cut(s) | 734 |
| BfoI | RGCGCY | 1 cut(s) | 268 |
| BisI | GCNGC | 5 cut(s) | 17, 285, 422, 490, 618 |
| BlsI | GCNGC | 5 cut(s) | 18, 286, 423, 491, 619 |
| Bme1390I | CCNGG | 2 cut(s) | 86, 560 |
| Bme18I | GGWCC | 1 cut(s) | 246 |
| BmeRI | GACNNNNNGTC | 2 cut(s) | 94, 136 |
| BmeT110I | CYCGRG | 1 cut(s) | 109 |
| BmgT120I | GGNCC | 2 cut(s) | 246, 324 |
| BmiI | GGNNCC | 3 cut(s) | 24, 226, 325 |
| BmrFI | CCNGG | 2 cut(s) | 86, 560 |
| BmsI | GCATC | 2 cut(s) | 169, 704 |
| BpiI | GAAGAC | 1 cut(s) | 135 |
| BplI | GAGNNNNNCTC | 2 cut(s) | 128, 160 |
| BpmI | CTGGAG | 1 cut(s) | 41 |
| BpuEI | CTTGAG | 1 cut(s) | 155 |
| BsaI | GGTCTC | 1 cut(s) | 45 |
| BsaJI | CCNNGG | 2 cut(s) | 476, 558 |
| BsaXI | ACNNNNNCTCC | 2 cut(s) | 251, 281 |
| Bse118I | RCCGGY | 1 cut(s) | 100 |
| Bse1I | ACTGG | 2 cut(s) | 266, 411 |
| Bse3DI | GCAATG | 1 cut(s) | 475 |
| BseBI | CCWGG | 2 cut(s) | 86, 560 |
| BseDI | CCNNGG | 2 cut(s) | 476, 558 |
| BseGI | GGATG | 5 cut(s) | 199, 373, 486, 660, 719 |
| BseMI | GCAATG | 1 cut(s) | 475 |
| BseNI | ACTGG | 2 cut(s) | 266, 411 |
| BsePI | GCGCGC | 1 cut(s) | 752 |
| BseXI | GCAGC | 4 cut(s) | 28, 271, 408, 476 |
| BseYI | CCCAGC | 2 cut(s) | 228, 532 |
| BsgI | GTGCAG | 1 cut(s) | 35 |
| Bsh1236I | CGCG | 1 cut(s) | 754 |
| BshFI | GGCC | 2 cut(s) | 326, 410 |
| BshNI | GGYRCC | 1 cut(s) | 224 |
| BsiHKCI | CYCGRG | 1 cut(s) | 109 |
| BsiSI | CCGG | 2 cut(s) | 101, 486 |
| BsmAI | GTCTC | 5 cut(s) | 39, 45, 173, 257, 643 |
| BsnI | GGCC | 2 cut(s) | 326, 410 |
| Bso31I | GGTCTC | 1 cut(s) | 45 |
| BsoBI | CYCGRG | 1 cut(s) | 109 |
| Bsp1286I | GDGCHC | 1 cut(s) | 441 |
| Bsp143I | GATC | 7 cut(s) | 117, 256, 355, 472, 639, 703, 736 |
| BspACI | CCGC | 1 cut(s) | 618 |
| BspANI | GGCC | 2 cut(s) | 326, 410 |
| BspFNI | CGCG | 1 cut(s) | 754 |
| BspLI | GGNNCC | 3 cut(s) | 24, 226, 325 |
| BspPI | GGATC | 5 cut(s) | 363, 467, 647, 711, 731 |
| BspT107I | GGYRCC | 1 cut(s) | 224 |
| BspTNI | GGTCTC | 1 cut(s) | 45 |
| BsrDI | GCAATG | 1 cut(s) | 475 |
| BsrFI | RCCGGY | 1 cut(s) | 100 |
| BsrI | ACTGG | 2 cut(s) | 266, 411 |
| BssAI | RCCGGY | 1 cut(s) | 100 |
| BssECI | CCNNGG | 2 cut(s) | 476, 558 |
| BssHII | GCGCGC | 1 cut(s) | 752 |
| BssMI | GATC | 7 cut(s) | 117, 256, 355, 472, 639, 703, 736 |
| Bst2UI | CCWGG | 2 cut(s) | 86, 560 |
| Bst4CI | ACNGT | 3 cut(s) | 452, 500, 509 |
| BstC8I | GCNNGC | 4 cut(s) | 102, 106, 550, 754 |
| BstDSI | CCRYGG | 1 cut(s) | 476 |
| BstF5I | GGATG | 5 cut(s) | 199, 373, 486, 660, 719 |
| BstFNI | CGCG | 1 cut(s) | 754 |
| BstH2I | RGCGCY | 1 cut(s) | 268 |
| BstHHI | GCGC | 3 cut(s) | 267, 754, 756 |
| BstKTI | GATC | 7 cut(s) | 120, 259, 358, 475, 642, 706, 739 |
| BstMAI | GTCTC | 5 cut(s) | 39, 45, 173, 257, 643 |
| BstMBI | GATC | 7 cut(s) | 117, 256, 355, 472, 639, 703, 736 |
| BstMWI | GCNNNNNNNGC | 3 cut(s) | 22, 554, 626 |
| BstNI | CCWGG | 2 cut(s) | 86, 560 |
| BstNSI | RCATGY | 1 cut(s) | 217 |
| BstSCI | CCNGG | 2 cut(s) | 84, 558 |
| BstUI | CGCG | 1 cut(s) | 754 |
| BstV1I | GCAGC | 4 cut(s) | 28, 271, 408, 476 |
| BstV2I | GAAGAC | 1 cut(s) | 135 |
| BstX2I | RGATCY | 3 cut(s) | 639, 703, 736 |
| BstYI | RGATCY | 3 cut(s) | 639, 703, 736 |
| BsuRI | GGCC | 2 cut(s) | 326, 410 |
| BtgI | CCRYGG | 1 cut(s) | 476 |
| BtgZI | GCGATG | 1 cut(s) | 192 |
| BtsCI | GGATG | 5 cut(s) | 199, 373, 486, 660, 719 |
| BtsIMutI | CAGTG | 2 cut(s) | 259, 448 |
| Cac8I | GCNNGC | 4 cut(s) | 102, 106, 550, 754 |
| CfoI | GCGC | 3 cut(s) | 267, 754, 756 |
| Cfr10I | RCCGGY | 1 cut(s) | 100 |
| Cfr13I | GGNCC | 2 cut(s) | 246, 324 |
| CseI | GACGC | 1 cut(s) | 525 |
| Csp6I | GTAC | 1 cut(s) | 404 |
| CviAII | CATG | 3 cut(s) | 214, 310, 746 |
| CviQI | GTAC | 1 cut(s) | 404 |
| DpnI | GATC | 7 cut(s) | 119, 258, 357, 474, 641, 705, 738 |
| DpnII | GATC | 7 cut(s) | 117, 256, 355, 472, 639, 703, 736 |
| DriI | GACNNNNNGTC | 2 cut(s) | 94, 136 |
| Eam1105I | GACNNNNNGTC | 2 cut(s) | 94, 136 |
| Eco24I | GRGCYC | 1 cut(s) | 441 |
| Eco31I | GGTCTC | 1 cut(s) | 45 |
| Eco47I | GGWCC | 1 cut(s) | 246 |
| Eco57I | CTGAAG | 1 cut(s) | 313 |
| Eco88I | CYCGRG | 1 cut(s) | 109 |
| EcoO109I | RGGNCCY | 2 cut(s) | 246, 324 |
| EcoRI | GAATTC | 1 cut(s) | 334 |
| EcoRII | CCWGG | 2 cut(s) | 84, 558 |
| EcoT38I | GRGCYC | 1 cut(s) | 441 |
| FaeI | CATG | 3 cut(s) | 217, 313, 749 |
| FatI | CATG | 3 cut(s) | 213, 309, 745 |
| FauNDI | CATATG | 1 cut(s) | 304 |
| Fnu4HI | GCNGC | 5 cut(s) | 17, 285, 422, 490, 618 |
| FokI | GGATG | 5 cut(s) | 206, 360, 493, 647, 726 |
| FriOI | GRGCYC | 1 cut(s) | 441 |
| Fsp4HI | GCNGC | 5 cut(s) | 17, 285, 422, 490, 618 |
| FspBI | CTAG | 1 cut(s) | 734 |
| GlaI | GCGC | 3 cut(s) | 266, 753, 755 |
| GluI | GCNGC | 5 cut(s) | 17, 285, 422, 490, 618 |
| GsaI | CCCAGC | 2 cut(s) | 232, 536 |
| GsuI | CTGGAG | 1 cut(s) | 41 |
| HaeII | RGCGCY | 1 cut(s) | 268 |
| HaeIII | GGCC | 2 cut(s) | 326, 410 |
| HapII | CCGG | 2 cut(s) | 101, 486 |
| HgaI | GACGC | 1 cut(s) | 525 |
| HhaI | GCGC | 3 cut(s) | 267, 754, 756 |
| Hin1II | CATG | 3 cut(s) | 217, 313, 749 |
| Hin6I | GCGC | 3 cut(s) | 265, 752, 754 |
| HinP1I | GCGC | 3 cut(s) | 265, 752, 754 |
| HinfI | GANTC | 3 cut(s) | 92, 137, 516 |
| HpaII | CCGG | 2 cut(s) | 101, 486 |
| HphI | GGTGA | 2 cut(s) | 44, 198 |
| Hpy188I | TCNGA | 1 cut(s) | 636 |
| Hpy188III | TCNNGA | 5 cut(s) | 170, 254, 331, 664, 740 |
| Hpy99I | CGWCG | 1 cut(s) | 100 |
| HpyAV | CCTTC | 3 cut(s) | 29, 337, 421 |
| HpyCH4III | ACNGT | 3 cut(s) | 452, 500, 509 |
| HpyCH4V | TGCA | 5 cut(s) | 16, 213, 219, 287, 302 |
| HpyF10VI | GCNNNNNNNGC | 3 cut(s) | 22, 554, 626 |
| Hsp92II | CATG | 3 cut(s) | 217, 313, 749 |
| HspAI | GCGC | 3 cut(s) | 265, 752, 754 |
| KroI | GCCGGC | 1 cut(s) | 100 |
| KroNI | GCCGGC | 1 cut(s) | 102 |
| Kzo9I | GATC | 7 cut(s) | 117, 256, 355, 472, 639, 703, 736 |
| LmnI | GCTCC | 3 cut(s) | 22, 40, 272 |
| Lsp1109I | GCAGC | 4 cut(s) | 28, 271, 408, 476 |
| LweI | GCATC | 2 cut(s) | 169, 704 |
| MaeI | CTAG | 1 cut(s) | 734 |
| MalI | GATC | 7 cut(s) | 119, 258, 357, 474, 641, 705, 738 |
| MboI | GATC | 7 cut(s) | 117, 256, 355, 472, 639, 703, 736 |
| MboII | GAAGA | 2 cut(s) | 140, 698 |
| MflI | RGATCY | 3 cut(s) | 639, 703, 736 |
| MhlI | GDGCHC | 1 cut(s) | 441 |
| MluCI | AATT | 2 cut(s) | 197, 334 |
| MlyI | GAGTC | 1 cut(s) | 146 |
| MnlI | CCTC | 6 cut(s) | 81, 184, 538, 630, 666, 694 |
| MroNI | GCCGGC | 1 cut(s) | 100 |
| MseI | TTAA | 1 cut(s) | 273 |
| MspA1I | CMGCKG | 1 cut(s) | 19 |
| MspI | CCGG | 2 cut(s) | 101, 486 |
| MspR9I | CCNGG | 2 cut(s) | 86, 560 |
| MvaI | CCWGG | 2 cut(s) | 86, 560 |
| MvnI | CGCG | 1 cut(s) | 754 |
| MwoI | GCNNNNNNNGC | 3 cut(s) | 22, 554, 626 |
| NaeI | GCCGGC | 1 cut(s) | 102 |
| NdeI | CATATG | 1 cut(s) | 304 |
| NdeII | GATC | 7 cut(s) | 117, 256, 355, 472, 639, 703, 736 |
| NgoMIV | GCCGGC | 1 cut(s) | 100 |
| NlaIII | CATG | 3 cut(s) | 217, 313, 749 |
| NlaIV | GGNNCC | 3 cut(s) | 24, 226, 325 |
| NspI | RCATGY | 1 cut(s) | 217 |
| PaeR7I | CTCGAG | 1 cut(s) | 109 |
| PauI | GCGCGC | 1 cut(s) | 752 |
| PdiI | GCCGGC | 1 cut(s) | 102 |
| PfeI | GAWTC | 2 cut(s) | 92, 516 |
| PkrI | GCNGC | 5 cut(s) | 18, 286, 423, 491, 619 |
| PleI | GAGTC | 1 cut(s) | 145 |
| PpsI | GAGTC | 1 cut(s) | 145 |
| PpuMI | RGGWCCY | 1 cut(s) | 246 |
| Psp5II | RGGWCCY | 1 cut(s) | 246 |
| Psp6I | CCWGG | 2 cut(s) | 84, 558 |
| PspFI | CCCAGC | 2 cut(s) | 228, 532 |
| PspGI | CCWGG | 2 cut(s) | 84, 558 |
| PspN4I | GGNNCC | 3 cut(s) | 24, 226, 325 |
| PspPI | GGNCC | 2 cut(s) | 246, 324 |
| PspPPI | RGGWCCY | 1 cut(s) | 246 |
| PspXI | VCTCGAGB | 1 cut(s) | 109 |
| PsrI | GAACNNNNNNTAC | 2 cut(s) | 488, 520 |
| PsuI | RGATCY | 3 cut(s) | 639, 703, 736 |
| PteI | GCGCGC | 1 cut(s) | 752 |
| PvuII | CAGCTG | 1 cut(s) | 19 |
| RsaI | GTAC | 1 cut(s) | 405 |
| RsaNI | GTAC | 1 cut(s) | 404 |
| SaqAI | TTAA | 1 cut(s) | 273 |
| SatI | GCNGC | 5 cut(s) | 17, 285, 422, 490, 618 |
| Sau3AI | GATC | 7 cut(s) | 117, 256, 355, 472, 639, 703, 736 |
| Sau96I | GGNCC | 2 cut(s) | 246, 324 |
| SchI | GAGTC | 1 cut(s) | 146 |
| ScrFI | CCNGG | 2 cut(s) | 86, 560 |
| SduI | GDGCHC | 1 cut(s) | 441 |
| SetI | ASST | 9 cut(s) | 21, 34, 110, 135, 211, 248, 286, 295, 604 |
| SfaNI | GCATC | 2 cut(s) | 169, 704 |
| Sfr274I | CTCGAG | 1 cut(s) | 109 |
| SinI | GGWCC | 1 cut(s) | 246 |
| SlaI | CTCGAG | 1 cut(s) | 109 |
| SmlI | CTYRAG | 2 cut(s) | 109, 134 |
| SmoI | CTYRAG | 2 cut(s) | 109, 134 |
| Sse9I | AATT | 2 cut(s) | 197, 334 |
| SsiI | CCGC | 1 cut(s) | 618 |
| SspMI | CTAG | 1 cut(s) | 734 |
| StyD4I | CCNGG | 2 cut(s) | 84, 558 |
| TaaI | ACNGT | 3 cut(s) | 452, 500, 509 |
| TaqI | TCGA | 4 cut(s) | 66, 110, 171, 255 |
| TasI | AATT | 2 cut(s) | 197, 334 |
| TauI | GCSGC | 1 cut(s) | 620 |
| TfiI | GAWTC | 2 cut(s) | 92, 516 |
| Tru1I | TTAA | 1 cut(s) | 273 |
| Tru9I | TTAA | 1 cut(s) | 273 |
| TscAI | CASTG | 2 cut(s) | 266, 455 |
| TseI | GCWGC | 4 cut(s) | 16, 284, 421, 489 |
| TspDTI | ATGAA | 6 cut(s) | 17, 210, 230, 327, 444, 762 |
| TspGWI | ACGGA | 3 cut(s) | 259, 493, 726 |
| TspRI | CASTG | 2 cut(s) | 266, 455 |
| VpaK11BI | GGWCC | 1 cut(s) | 246 |
| XapI | RAATTY | 1 cut(s) | 334 |
| XceI | RCATGY | 1 cut(s) | 217 |
| XhoI | CTCGAG | 1 cut(s) | 109 |
| XspI | CTAG | 1 cut(s) | 734 |