MD11G1117800.v1.1

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr11
OG0003498
Physical Location & Seq
Reverse (-)
10674960 .. 10675523
564 bp
Loading structure...
UTR
Exon/CDS
Intron
MD11G1117800.v1.1.491

Sequence Viewer

Length: 312 bp
ATGTCTGGACGCGGAAAGGGAGGCAAGGTGTTCGGCAAGGGAGGAGCAAAACGTCACCGGAAGATCCTCCGTGACAACATCCAGGGCATCACCAAGCCAGCGATTCGCCGCCTGGCCCGCAGAGGTGGCGTGAAGCGAATCAGCGGCCTGATATACGAGGAGACTCGCGGCGTCCTCAAGATCTTTCTCGAGAATGTGATTCGTGATGCCGTTACCTACACGGAGCATGCAAGGAGGAAGACGGTGACGGCCATGGACGTTGTCTATGCGCTCAAGAGGCAGGGCAGGACTCTGTACGGGTTCGGGGGTTAA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
ko05034 ko05203 ko05322 map05034 map05203 map05322
Pfam Domains
Protein Families
CENP-T_C

Protein Analysis

104

Amino Acids

11.5

Weight (kDa)

11.48

Isoelectric Point (pI)

47.22

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
CENP-T_C PF15511 44 - 96 3.6e-08 Centromere kinetochore component CENP-T histone fold
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccII CGCG 2 cut(s) 12, 168
AciI CCGC 5 cut(s) 12, 109, 118, 144, 168
AclWI GGATC 1 cut(s) 58
AcoI YGGCCR 1 cut(s) 249
AcyI GRCGYC 1 cut(s) 171
AfaI GTAC 1 cut(s) 296
AjnI CCWGG 2 cut(s) 81, 111
Alw26I GTCTC 1 cut(s) 155
AlwI GGATC 1 cut(s) 58
Ama87I CYCGRG 1 cut(s) 188
AoxI GGCC 3 cut(s) 114, 145, 249
AspLEI GCGC 1 cut(s) 271
AspS9I GGNCC 1 cut(s) 115
AsuHPI GGTGA 3 cut(s) 47, 82, 256
AvaI CYCGRG 1 cut(s) 188
BbsI GAAGAC 1 cut(s) 245
BceAI ACGGC 2 cut(s) 194, 264
BcgI CGANNNNNNTGC 2 cut(s) 13, 47
BciT130I CCWGG 2 cut(s) 83, 113
BcoDI GTCTC 1 cut(s) 155
BglII AGATCT 1 cut(s) 180
BisI GCNGC 3 cut(s) 109, 145, 169
BlsI GCNGC 3 cut(s) 110, 146, 170
Bme1390I CCNGG 2 cut(s) 83, 113
BmeT110I CYCGRG 1 cut(s) 188
BmgT120I GGNCC 1 cut(s) 115
BmrFI CCNGG 2 cut(s) 83, 113
BmsI GCATC 2 cut(s) 96, 196
BpiI GAAGAC 1 cut(s) 245
BpuEI CTTGAG 2 cut(s) 161, 257
BsaHI GRCGYC 1 cut(s) 171
BsaJI CCNNGG 2 cut(s) 82, 252
BsaWI WCCGGW 1 cut(s) 57
BsaXI ACNNNNNCTCC 2 cut(s) 12, 42
BseBI CCWGG 2 cut(s) 83, 113
BseDI CCNNGG 2 cut(s) 82, 252
BseGI GGATG 1 cut(s) 78
BseRI GAGGAG 2 cut(s) 57, 173
Bsh1236I CGCG 2 cut(s) 12, 168
BshFI GGCC 3 cut(s) 116, 147, 251
BsiHKCI CYCGRG 1 cut(s) 188
BsiSI CCGG 1 cut(s) 58
BsmAI GTCTC 1 cut(s) 155
BsnI GGCC 3 cut(s) 116, 147, 251
BsoBI CYCGRG 1 cut(s) 188
Bsp143I GATC 2 cut(s) 63, 180
Bsp19I CCATGG 1 cut(s) 252
BspACI CCGC 5 cut(s) 12, 109, 118, 144, 168
BspANI GGCC 3 cut(s) 116, 147, 251
BspFNI CGCG 2 cut(s) 12, 168
BspPI GGATC 1 cut(s) 58
BssECI CCNNGG 2 cut(s) 82, 252
BssMI GATC 2 cut(s) 63, 180
BssNI GRCGYC 1 cut(s) 171
BssT1I CCWWGG 1 cut(s) 252
Bst2UI CCWGG 2 cut(s) 83, 113
Bst4CI ACNGT 1 cut(s) 244
BstACI GRCGYC 1 cut(s) 171
BstC8I GCNNGC 3 cut(s) 99, 118, 228
BstDSI CCRYGG 1 cut(s) 252
BstF5I GGATG 1 cut(s) 78
BstFNI CGCG 2 cut(s) 12, 168
BstHHI GCGC 1 cut(s) 271
BstKTI GATC 2 cut(s) 66, 183
BstMAI GTCTC 1 cut(s) 155
BstMBI GATC 2 cut(s) 63, 180
BstMWI GCNNNNNNNGC 3 cut(s) 117, 126, 277
BstNI CCWGG 2 cut(s) 83, 113
BstNSI RCATGY 1 cut(s) 230
BstSCI CCNGG 2 cut(s) 81, 111
BstUI CGCG 2 cut(s) 12, 168
BstV2I GAAGAC 1 cut(s) 245
BstX2I RGATCY 2 cut(s) 63, 180
BstYI RGATCY 2 cut(s) 63, 180
BsuRI GGCC 3 cut(s) 116, 147, 251
BtgI CCRYGG 1 cut(s) 252
BtsCI GGATG 1 cut(s) 78
Cac8I GCNNGC 3 cut(s) 99, 118, 228
CfoI GCGC 1 cut(s) 271
Cfr13I GGNCC 1 cut(s) 115
CseI GACGC 2 cut(s) 18, 160
Csp6I GTAC 1 cut(s) 295
CviAII CATG 2 cut(s) 227, 253
CviJI RGCY 4 cut(s) 97, 116, 147, 251
CviKI_1 RGCY 4 cut(s) 97, 116, 147, 251
CviQI GTAC 1 cut(s) 295
DpnI GATC 2 cut(s) 65, 182
DpnII GATC 2 cut(s) 63, 180
EaeI YGGCCR 1 cut(s) 249
Eco130I CCWWGG 1 cut(s) 252
Eco88I CYCGRG 1 cut(s) 188
EcoRII CCWGG 2 cut(s) 81, 111
EcoT14I CCWWGG 1 cut(s) 252
ErhI CCWWGG 1 cut(s) 252
FaeI CATG 2 cut(s) 230, 256
FaiI YATR 4 cut(s) 154, 228, 254, 267
FatI CATG 2 cut(s) 226, 252
FauI CCCGC 1 cut(s) 125
Fnu4HI GCNGC 3 cut(s) 109, 145, 169
FokI GGATG 1 cut(s) 65
Fsp4HI GCNGC 3 cut(s) 109, 145, 169
GlaI GCGC 1 cut(s) 270
GluI GCNGC 3 cut(s) 109, 145, 169
HaeIII GGCC 3 cut(s) 116, 147, 251
HapII CCGG 1 cut(s) 58
HgaI GACGC 2 cut(s) 18, 160
HhaI GCGC 1 cut(s) 271
Hin1I GRCGYC 1 cut(s) 171
Hin1II CATG 2 cut(s) 230, 256
Hin6I GCGC 1 cut(s) 269
HinP1I GCGC 1 cut(s) 269
HinfI GANTC 5 cut(s) 103, 138, 163, 199, 289
HpaII CCGG 1 cut(s) 58
HphI GGTGA 3 cut(s) 47, 82, 256
Hpy188III TCNNGA 6 cut(s) 6, 178, 188, 190, 203, 274
HpyCH4III ACNGT 1 cut(s) 244
HpyCH4IV ACGT 2 cut(s) 52, 258
HpyCH4V TGCA 1 cut(s) 230
HpyF10VI GCNNNNNNNGC 3 cut(s) 117, 126, 277
HpySE526I ACGT 2 cut(s) 52, 258
Hsp92I GRCGYC 1 cut(s) 171
Hsp92II CATG 2 cut(s) 230, 256
HspAI GCGC 1 cut(s) 269
Kzo9I GATC 2 cut(s) 63, 180
LmnI GCTCC 2 cut(s) 44, 223
LpnPI CCDG 9 cut(s) 68, 71, 95, 98, 111, 125, 161, 266, 271
LweI GCATC 2 cut(s) 96, 196
MaeII ACGT 2 cut(s) 52, 258
MaeIII GTNAC 4 cut(s) 53, 71, 211, 244
MalI GATC 2 cut(s) 65, 182
MboI GATC 2 cut(s) 63, 180
MboII GAAGA 2 cut(s) 73, 250
MflI RGATCY 2 cut(s) 63, 180
MlyI GAGTC 2 cut(s) 157, 283
MnlI CCTC 8 cut(s) 14, 35, 77, 116, 151, 185, 228, 270
MseI TTAA 1 cut(s) 310
MspA1I CMGCKG 1 cut(s) 144
MspI CCGG 1 cut(s) 58
MspR9I CCNGG 2 cut(s) 83, 113
MvaI CCWGG 2 cut(s) 83, 113
MvnI CGCG 2 cut(s) 12, 168
MwoI GCNNNNNNNGC 3 cut(s) 117, 126, 277
NcoI CCATGG 1 cut(s) 252
NdeII GATC 2 cut(s) 63, 180
NlaIII CATG 2 cut(s) 230, 256
NmuCI GTSAC 3 cut(s) 53, 71, 244
NspI RCATGY 1 cut(s) 230
PaeI GCATGC 1 cut(s) 230
PaeR7I CTCGAG 1 cut(s) 188
PfeI GAWTC 3 cut(s) 103, 138, 199
PflFI GACNNNGTC 1 cut(s) 260
PkrI GCNGC 3 cut(s) 110, 146, 170
PleI GAGTC 2 cut(s) 157, 283
PpsI GAGTC 2 cut(s) 157, 283
Psp6I CCWGG 2 cut(s) 81, 111
PspGI CCWGG 2 cut(s) 81, 111
PspPI GGNCC 1 cut(s) 115
PsuI RGATCY 2 cut(s) 63, 180
PsyI GACNNNGTC 1 cut(s) 260
RsaI GTAC 1 cut(s) 296
RsaNI GTAC 1 cut(s) 295
SaqAI TTAA 1 cut(s) 310
SatI GCNGC 3 cut(s) 109, 145, 169
Sau3AI GATC 2 cut(s) 63, 180
Sau96I GGNCC 1 cut(s) 115
SchI GAGTC 2 cut(s) 157, 283
ScrFI CCNGG 2 cut(s) 83, 113
SetI ASST 5 cut(s) 30, 55, 127, 218, 261
SfaNI GCATC 2 cut(s) 96, 196
Sfr274I CTCGAG 1 cut(s) 188
SlaI CTCGAG 1 cut(s) 188
SmlI CTYRAG 3 cut(s) 176, 188, 272
SmoI CTYRAG 3 cut(s) 176, 188, 272
SphI GCATGC 1 cut(s) 230
SsiI CCGC 5 cut(s) 12, 109, 118, 144, 168
StyD4I CCNGG 2 cut(s) 81, 111
StyI CCWWGG 1 cut(s) 252
TaaI ACNGT 1 cut(s) 244
TaiI ACGT 2 cut(s) 55, 261
TaqI TCGA 1 cut(s) 189
TauI GCSGC 3 cut(s) 111, 147, 171
TfiI GAWTC 3 cut(s) 103, 138, 199
Tru1I TTAA 1 cut(s) 310
Tru9I TTAA 1 cut(s) 310
TseFI GTSAC 3 cut(s) 53, 71, 244
Tsp45I GTSAC 3 cut(s) 53, 71, 244
TspGWI ACGGA 2 cut(s) 59, 236
Tth111I GACNNNGTC 1 cut(s) 260
XceI RCATGY 1 cut(s) 230
XhoI CTCGAG 1 cut(s) 188
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.