MD15G1199700.v1.1

May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr15
OG0004629
Physical Location & Seq
Reverse (-)
15878396 .. 15881761
3366 bp
Loading structure...
UTR
Exon/CDS
Intron
MD15G1199700.v1.1.491

Sequence Viewer

Length: 732 bp
ATGTCTTCTCCTGCCGAATGGTATCAGTCACTCCCACCCATAAGCAAGGCTTATGGTACCCTCTGTGTAATTGCAACTACAGCCTTTCAATTGGGGTTTTATGATTGGAAAAGTATTGCATTAGTACATAAACTAGTATTCTTGCATTTCCAGGTTTGGAGGTTGTTTACAAACTTCTTTTTCCTTGGAAACTTCTCCGTCAACTTTGGAATCCGCCTTCTGATGATAGCAAGATATGGGGTTCAACTTGAAAAGGGACCATTTGATCGACGAACAGCAGATTTCTTGTGGATGATGGTATTTGGAGCCACGACATTGTTGGTTTTATCTGCTATCCCTATTTTCTATTCTCCTTTCTTGGGGGTATCTCTCGTGTTCATGCTTGTTTATGTTTGGAGTAGAGAATTTCCGAATGCCAACGTCAACATATATGGTCTCGTGCAACTTAAGGCGTTTTATCTACCTTGGGCAATGCTTGCTTTGGACGTCATCTTTGGTTCCCCAATTATGCCAGATCTGCTGGGAATCATTGCCGGACATCTGTTTTACTTCTTGACTGTGTTGCATCCATTGGCAGGTGGAAAGAACATATTACAGACTCCAAGATGGGTACGTAAAATAGTCGCAAGATGGAGGATAGGAGCTCCTCCACCAACTAGCCGAACCCAAGAACCTGCCCCAGCTGCTGCTGGTGTGGCTTTCAGAGGGAGGTCTTATCGACTTAGCGAATGA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
ko04141 map04141
Pfam Domains
Protein Families
DER1

Protein Analysis

244

Amino Acids

27.55

Weight (kDa)

10.04

Isoelectric Point (pI)

46.39

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
DER1 PF04511 11 - 201 6.1e-44 Der1-like family
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
Loading...
Style Settings
Image
Tree File
Tip: Beautify your tree with professional tools

Download the Full Tree (.nwk) file, then upload it to any of the following tools to customize colors, fonts, annotations, clades, and branch support.

Publication-ready
iTOL Interactive Tree Of Life · Most popular EvolView Flexible annotations MEGA Desktop phylogenetics suite FigTree Desktop tree editor

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AarI CACCTGC 1 cut(s) 566
AatII GACGTC 1 cut(s) 489
Acc36I ACCTGC 2 cut(s) 566, 682
Acc65I GGTACC 1 cut(s) 56
AccB1I GGYRCC 1 cut(s) 56
AciI CCGC 1 cut(s) 214
AcsI RAATTY 1 cut(s) 404
AcyI GRCGYC 1 cut(s) 486
AfaI GTAC 3 cut(s) 58, 126, 612
AfiI CCNNNNNNNGG 2 cut(s) 359, 575
AflII CTTAAG 1 cut(s) 446
AgsI TTSAA 3 cut(s) 89, 245, 251
AhlI ACTAGT 1 cut(s) 133
AjnI CCWGG 1 cut(s) 150
AluBI AGCT 2 cut(s) 644, 683
AluI AGCT 2 cut(s) 644, 683
Alw21I GWGCWC 1 cut(s) 646
Alw26I GTCTC 1 cut(s) 440
AlwNI CAGNNNCTG 1 cut(s) 686
ApeKI GCWGC 2 cut(s) 683, 686
ApoI RAATTY 1 cut(s) 404
ArsI GACNNNNNNTTYG 2 cut(s) 476, 508
Asp718I GGTACC 1 cut(s) 56
AspS9I GGNCC 1 cut(s) 257
AvaII GGWCC 1 cut(s) 257
BanI GGYRCC 1 cut(s) 56
BanII GRGCYC 1 cut(s) 646
BauI CACGAG 2 cut(s) 371, 437
Bbv12I GWGCWC 1 cut(s) 646
BbvI GCAGC 2 cut(s) 670, 673
BccI CCATC 3 cut(s) 289, 600, 624
BciT130I CCWGG 1 cut(s) 152
BcoDI GTCTC 1 cut(s) 440
BcuI ACTAGT 1 cut(s) 133
BfaI CTAG 2 cut(s) 134, 657
BfmI CTRYAG 1 cut(s) 78
BfrI CTTAAG 1 cut(s) 446
BfuAI ACCTGC 2 cut(s) 566, 682
BglII AGATCT 1 cut(s) 514
BisI GCNGC 2 cut(s) 684, 687
BlsI GCNGC 2 cut(s) 685, 688
Bme1390I CCNGG 1 cut(s) 152
Bme18I GGWCC 1 cut(s) 257
BmgT120I GGNCC 1 cut(s) 257
BmiI GGNNCC 4 cut(s) 58, 258, 307, 499
BmrFI CCNGG 1 cut(s) 152
BmsI GCATC 1 cut(s) 574
BsaAI YACGTR 1 cut(s) 614
BsaHI GRCGYC 1 cut(s) 486
BsaI GGTCTC 1 cut(s) 440
BsaJI CCNNGG 2 cut(s) 184, 464
Bsc4I CCNNNNNNNGG 2 cut(s) 359, 575
Bse3DI GCAATG 2 cut(s) 477, 528
BseBI CCWGG 1 cut(s) 152
BseDI CCNNGG 2 cut(s) 184, 464
BseGI GGATG 2 cut(s) 297, 565
BseLI CCNNNNNNNGG 2 cut(s) 359, 575
BseMI GCAATG 2 cut(s) 477, 528
BseRI GAGGAG 1 cut(s) 636
BseXI GCAGC 2 cut(s) 670, 673
BseYI CCCAGC 2 cut(s) 520, 679
BshNI GGYRCC 1 cut(s) 56
BsiHKAI GWGCWC 1 cut(s) 646
BsiSI CCGG 1 cut(s) 534
BslFI GGGAC 1 cut(s) 270
BslI CCNNNNNNNGG 2 cut(s) 359, 575
BsmAI GTCTC 1 cut(s) 440
BsmFI GGGAC 1 cut(s) 270
BsmI GAATGC 1 cut(s) 418
Bso31I GGTCTC 1 cut(s) 440
Bsp1286I GDGCHC 1 cut(s) 646
Bsp143I GATC 2 cut(s) 265, 514
BspACI CCGC 1 cut(s) 214
BspLI GGNNCC 4 cut(s) 58, 258, 307, 499
BspMI ACCTGC 2 cut(s) 566, 682
BspT107I GGYRCC 1 cut(s) 56
BspTI CTTAAG 1 cut(s) 446
BspTNI GGTCTC 1 cut(s) 440
BsrDI GCAATG 2 cut(s) 477, 528
BssECI CCNNGG 2 cut(s) 184, 464
BssMI GATC 2 cut(s) 265, 514
BssNI GRCGYC 1 cut(s) 486
BssSI CACGAG 2 cut(s) 371, 437
BssT1I CCWWGG 2 cut(s) 184, 464
Bst2BI CACGAG 2 cut(s) 371, 437
Bst2UI CCWGG 1 cut(s) 152
Bst4CI ACNGT 1 cut(s) 559
BstACI GRCGYC 1 cut(s) 486
BstAFI CTTAAG 1 cut(s) 446
BstAPI GCANNNNNTGC 1 cut(s) 476
BstBAI YACGTR 1 cut(s) 614
BstC8I GCNNGC 1 cut(s) 477
BstDEI CTNAG 1 cut(s) 722
BstF5I GGATG 2 cut(s) 297, 565
BstKTI GATC 2 cut(s) 268, 517
BstMAI GTCTC 1 cut(s) 440
BstMBI GATC 2 cut(s) 265, 514
BstMWI GCNNNNNNNGC 5 cut(s) 80, 476, 517, 683, 695
BstNI CCWGG 1 cut(s) 152
BstSCI CCNGG 1 cut(s) 150
BstSFI CTRYAG 1 cut(s) 78
BstSNI TACGTA 1 cut(s) 614
BstV1I GCAGC 2 cut(s) 670, 673
BstX2I RGATCY 1 cut(s) 514
BstYI RGATCY 1 cut(s) 514
BtsCI GGATG 2 cut(s) 297, 565
BveI ACCTGC 2 cut(s) 566, 682
Cac8I GCNNGC 1 cut(s) 477
CaiI CAGNNNCTG 1 cut(s) 686
Cfr13I GGNCC 1 cut(s) 257
Csp6I GTAC 3 cut(s) 57, 125, 611
CviAII CATG 1 cut(s) 379
CviJI RGCY 7 cut(s) 50, 83, 308, 644, 660, 683, 698
CviKI_1 RGCY 7 cut(s) 50, 83, 308, 644, 660, 683, 698
CviQI GTAC 3 cut(s) 57, 125, 611
DdeI CTNAG 1 cut(s) 722
DpnI GATC 2 cut(s) 267, 516
DpnII GATC 2 cut(s) 265, 514
EciI GGCGGA 1 cut(s) 203
Ecl136II GAGCTC 1 cut(s) 644
Eco105I TACGTA 1 cut(s) 614
Eco130I CCWWGG 2 cut(s) 184, 464
Eco24I GRGCYC 1 cut(s) 646
Eco31I GGTCTC 1 cut(s) 440
Eco47I GGWCC 1 cut(s) 257
Eco53kI GAGCTC 1 cut(s) 644
EcoICRI GAGCTC 1 cut(s) 644
EcoRII CCWGG 1 cut(s) 150
EcoT14I CCWWGG 2 cut(s) 184, 464
EcoT38I GRGCYC 1 cut(s) 646
ErhI CCWWGG 2 cut(s) 184, 464
FaeI CATG 1 cut(s) 382
FalI AAGNNNNNCTT 2 cut(s) 34, 66
FaqI GGGAC 1 cut(s) 270
FatI CATG 1 cut(s) 378
Fnu4HI GCNGC 2 cut(s) 684, 687
FokI GGATG 2 cut(s) 304, 552
FriOI GRGCYC 1 cut(s) 646
Fsp4HI GCNGC 2 cut(s) 684, 687
FspBI CTAG 2 cut(s) 134, 657
GluI GCNGC 2 cut(s) 684, 687
GsaI CCCAGC 2 cut(s) 524, 683
HapII CCGG 1 cut(s) 534
Hin1I GRCGYC 1 cut(s) 486
Hin1II CATG 1 cut(s) 382
HincII GTYRAC 2 cut(s) 202, 424
HindII GTYRAC 2 cut(s) 202, 424
HinfI GANTC 3 cut(s) 210, 525, 598
HpaII CCGG 1 cut(s) 534
Hpy166II GTNNAC 3 cut(s) 168, 202, 424
Hpy188I TCNGA 3 cut(s) 222, 411, 704
Hpy188III TCNNGA 1 cut(s) 553
Hpy8I GTNNAC 3 cut(s) 168, 202, 424
Hpy99I CGWCG 1 cut(s) 273
HpyAV CCTTC 1 cut(s) 227
HpyCH4III ACNGT 1 cut(s) 559
HpyCH4IV ACGT 3 cut(s) 420, 486, 613
HpyCH4V TGCA 5 cut(s) 74, 119, 145, 442, 565
HpyF10VI GCNNNNNNNGC 5 cut(s) 80, 476, 517, 683, 695
HpyF3I CTNAG 1 cut(s) 722
HpySE526I ACGT 3 cut(s) 420, 486, 613
Hsp92I GRCGYC 1 cut(s) 486
Hsp92II CATG 1 cut(s) 382
KpnI GGTACC 1 cut(s) 60
Kzo9I GATC 2 cut(s) 265, 514
LmnI GCTCC 3 cut(s) 305, 641, 649
Lsp1109I GCAGC 2 cut(s) 670, 673
LweI GCATC 1 cut(s) 574
MaeI CTAG 2 cut(s) 134, 657
MaeII ACGT 3 cut(s) 420, 486, 613
MaeIII GTNAC 1 cut(s) 27
MalI GATC 2 cut(s) 267, 516
MboI GATC 2 cut(s) 265, 514
MfeI CAATTG 1 cut(s) 89
MflI RGATCY 1 cut(s) 514
MhlI GDGCHC 1 cut(s) 646
MluCI AATT 4 cut(s) 69, 89, 404, 504
MlyI GAGTC 1 cut(s) 592
MnlI CCTC 6 cut(s) 71, 153, 627, 657, 698, 702
MseI TTAA 1 cut(s) 447
MspA1I CMGCKG 1 cut(s) 683
MspCI CTTAAG 1 cut(s) 446
MspI CCGG 1 cut(s) 534
MspR9I CCNGG 1 cut(s) 152
MunI CAATTG 1 cut(s) 89
Mva1269I GAATGC 1 cut(s) 418
MvaI CCWGG 1 cut(s) 152
MwoI GCNNNNNNNGC 5 cut(s) 80, 476, 517, 683, 695
NdeII GATC 2 cut(s) 265, 514
NlaIII CATG 1 cut(s) 382
NlaIV GGNNCC 4 cut(s) 58, 258, 307, 499
NmuCI GTSAC 1 cut(s) 27
PaqCI CACCTGC 1 cut(s) 566
PctI GAATGC 1 cut(s) 418
PfeI GAWTC 2 cut(s) 210, 525
PkrI GCNGC 2 cut(s) 685, 688
PleI GAGTC 1 cut(s) 592
PpsI GAGTC 1 cut(s) 592
Ppu21I YACGTR 1 cut(s) 614
Psp124BI GAGCTC 1 cut(s) 646
Psp6I CCWGG 1 cut(s) 150
PspFI CCCAGC 2 cut(s) 520, 679
PspGI CCWGG 1 cut(s) 150
PspN4I GGNNCC 4 cut(s) 58, 258, 307, 499
PspPI GGNCC 1 cut(s) 257
PstNI CAGNNNCTG 1 cut(s) 686
PsuI RGATCY 1 cut(s) 514
PvuII CAGCTG 1 cut(s) 683
RsaI GTAC 3 cut(s) 58, 126, 612
RsaNI GTAC 3 cut(s) 57, 125, 611
SacI GAGCTC 1 cut(s) 646
SaqAI TTAA 1 cut(s) 447
SatI GCNGC 2 cut(s) 684, 687
Sau3AI GATC 2 cut(s) 265, 514
Sau96I GGNCC 1 cut(s) 257
SchI GAGTC 1 cut(s) 592
ScrFI CCNGG 1 cut(s) 152
SduI GDGCHC 1 cut(s) 646
SfaNI GCATC 1 cut(s) 574
SfcI CTRYAG 1 cut(s) 78
SinI GGWCC 1 cut(s) 257
SmlI CTYRAG 1 cut(s) 446
SmoI CTYRAG 1 cut(s) 446
SnaBI TACGTA 1 cut(s) 614
SpeI ACTAGT 1 cut(s) 133
Sse9I AATT 4 cut(s) 69, 89, 404, 504
SsiI CCGC 1 cut(s) 214
SspMI CTAG 2 cut(s) 134, 657
SstI GAGCTC 1 cut(s) 646
StyD4I CCNGG 1 cut(s) 150
StyI CCWWGG 2 cut(s) 184, 464
TaaI ACNGT 1 cut(s) 559
TaiI ACGT 3 cut(s) 423, 489, 616
TaqI TCGA 2 cut(s) 268, 718
TasI AATT 4 cut(s) 69, 89, 404, 504
TatI WGTACW 1 cut(s) 124
TfiI GAWTC 2 cut(s) 210, 525
Tru1I TTAA 1 cut(s) 447
Tru9I TTAA 1 cut(s) 447
TseFI GTSAC 1 cut(s) 27
TseI GCWGC 2 cut(s) 683, 686
Tsp45I GTSAC 1 cut(s) 27
TspDTI ATGAA 1 cut(s) 367
TspGWI ACGGA 1 cut(s) 187
Vha464I CTTAAG 1 cut(s) 446
VpaK11BI GGWCC 1 cut(s) 257
XapI RAATTY 1 cut(s) 404
XcmI CCANNNNNNNNNTGG 1 cut(s) 316
XspI CTAG 2 cut(s) 134, 657
ZraI GACGTC 1 cut(s) 487
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.