Basic Information

Type: gene

Biological Identity

Species

malus_domestica

Chromosome

Chr17

Orthogroup ID

OG0006646

Physical Location & Seq

Genomic Coordinates Forward (+)

26593656 .. 26598458

Gene Structure 4803 bp

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UTR

Exon/CDS

Intron

Transcript / Protein ID

MD17G1218700.v1.1.491

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1224 bp

ATGGCTGCCGCTCCTGCTTGTCTCCAACTCAACGCTAAACCCTTCAGCTCCTTTCTCTCTCCCAACCCCATTTCCAAACACACCCCGAAAGTGGGTAGGATCAGTTGCTCCGCAGCCTCACCCTCTAAACGCTACTCCATCACTTTGCTTCCCGGCGATGGCATTGGCCCCGAAGTCATCTCCGTCGCCAAGAACGTCCTCAACCTCGCCGCCTCCATCGATGGGATTGAGTTTAAGTATGAAGAAGTACCTATTGGTGGAGCTGCCTTGGATTTGACTGGAGTTCCACTACCTGATGAGACCCTTTTGTCAGCTAAGCAATCCGATGCAGTTCTTCTCGGAGCAATTGGGGGGTACAAATGGGATAAGAACGAAAAGCACTTGAAACCAGAAACTGGCTTGCTTAAACTTCGCCAAGGTCTTAAAGTGTTTGCGAATCTGAGGCCTGCAACTGTTTTGCCGCAGTTAGTGGACGCTTCAACTTTGAAGAGAGAAGTAGCTGAGGGGGTTGACCTTATGGTTGTAAGAGAGCTCACTGGAGGTATATATTTTGGAAAGCCTAGGGGTTTTGGCACCAATGAAAATGGCGAGGAGATTGGCTTCAATACAGAGGTGTATGCTGCCTATGAGATTGATCGAATTGCTCGTGTTGCATTTGAGACTGCTCGGAAGCGAAAGGGGAGGCTCTGCAGTGTTGACAAGGCAAATGTGTTGGAGGCATCAATGTTTTGGAGGAAAAGAATCATGGAAATAGCCTTGGAGTATCCTGATGTTGAACTCTCACACATGTATGTTGATAATGCTGCAATGCAGCTTATTCGTGATCCGAAACAGTTTGATACGATTGTAACGAACAACATATTTGGCGATATATTATCTGATGAGGCTTCAATGATAACTGGAAGTATTGGGATGCTGCCATCTGCTAGTCTTGGGGAATCGGGTCCTGGACTTTATGAACCCATACATGGTTCTGCTCCCGATATTGCTGGACAGGATAAAGCAAACCCATTAGCGACAGTTCTCAGTGCTGCTATGCTTTTGAAGTACGGTTTAGGTGAAGAAAAGGCTGCCAAGAGAATTGAGGATGCAGTTCTAGATACTTTGAATAGGGGGTTTCGGACTGGTGACATATATTCCACTGGAACTAAATTGGTAGGATGCAAAGAAATGGGTGAAGAGGTATTGAAGTCTGTTGATTCCCAAGTTCCTTCTCCAGTATGA

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0005575 GO:0005622 GO:0005623 GO:0005737 GO:0006082 GO:0006790 GO:0006807 GO:0006950 GO:0006970 GO:0008150 GO:0008152 GO:0009058 GO:0009507 GO:0009526 GO:0009532 GO:0009536 GO:0009570 GO:0009579 GO:0009628 GO:0009651 GO:0009941 GO:0009987 GO:0016143 GO:0016144 GO:0019748 GO:0019757 GO:0019758 GO:0019760 GO:0019761 GO:0031967 GO:0031975 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0043436 GO:0044237 GO:0044249 GO:0044272 GO:0044281 GO:0044422 GO:0044424 GO:0044434 GO:0044435 GO:0044444 GO:0044446 GO:0044464 GO:0044550 GO:0050896 GO:0071704 GO:1901135 GO:1901137 GO:1901564 GO:1901566 GO:1901576 GO:1901657 GO:1901659

KEGG Pathways

Metabolic & Signaling

ko00290 ko00660 ko00966 ko01100 ko01110 ko01210 ko01230 map00290 map00660 map00966 map01100 map01110 map01210 map01230

Pfam Domains

Protein Families

Iso_dh

Protein Analysis

408

Amino Acids

43.71

Weight (kDa)

5.51

Isoelectric Point (pI)

32.75

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
Iso_dh	PF00180	47 - 395	1.2e-140	Isocitrate/isopropylmalate dehydrogenase

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

Style Settings

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

iTOL Interactive Tree Of Life · Most popular EvolView Flexible annotations MEGA Desktop phylogenetics suite FigTree Desktop tree editor

Orthologous Genes (Group: OG0006646)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT1G31180 AT1G31180 AT1G80560 AT5G14200 AT5G14200
fragaria_vesca	FvH4_2g04971
malus_domestica	MD17G1218700.v1.1
prunus_persica	Prupe.3G094300_v2.0.a1 Prupe.3G094300_v2.0.a1
pyrus_communis	pycom17g22270 pycom17g22330
rosa_chinensis	RchiOBHm_Chr2g0133781 RchiOBHm_Chr2g0133821
rosa_laevigata	RLG00000019364
rosa_multiflora	Rmu_sc0001782.1_g000049 Rmu_sc0001782.1_g000053 Rmu_sc0003682.1_g000003 Rmu_sc0004983.1_g000001
rosa_roxburghii	Rroxscaffold_2G00110790 Rroxscaffold_2G00110820
rosa_rugosa	Rorug02G0313900
rosa_samantha	Rh2AG367200 Rh2CG350300 Rh2CG350600 Rh2DG389700
rosa_wichuraiana	Rw2G029860

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AasI	GACNNNNNNGTC	1 cut(s)	307
AccB1I	GGYRCC	1 cut(s)	572
AccB7I	CCANNNNNTGG	1 cut(s)	395
AccBSI	CCGCTC	1 cut(s)	11
AciI	CCGC	4 cut(s)	9, 111, 210, 461
AclWI	GGATC	2 cut(s)	107, 818
AcuI	CTGAAG	1 cut(s)	28
AfaI	GTAC	3 cut(s)	249, 356, 1049
AfiI	CCNNNNNNNGG	7 cut(s)	91, 92, 158, 222, 257, 395, 968
AflIII	ACRYGT	1 cut(s)	786
AgsI	TTSAA	9 cut(s)	385, 480, 487, 604, 776, 891, 1045, 1108, 1189
AjnI	CCWGG	1 cut(s)	946
AjuI	GAANNNNNNNTTGG	2 cut(s)	237, 269
AluBI	AGCT	6 cut(s)	48, 263, 314, 500, 532, 814
AluI	AGCT	6 cut(s)	48, 263, 314, 500, 532, 814
Alw21I	GWGCWC	1 cut(s)	534
Alw26I	GTCTC	3 cut(s)	26, 293, 653
AlwI	GGATC	2 cut(s)	107, 818
AlwNI	CAGNNNCTG	1 cut(s)	395
AoxI	GGCC	2 cut(s)	166, 443
ApeKI	GCWGC	9 cut(s)	5, 113, 263, 620, 803, 811, 916, 1031, 1070
AspA2I	CCTAGG	1 cut(s)	560
AspS9I	GGNCC	2 cut(s)	167, 944
AsuC2I	CCSGG	1 cut(s)	153
AsuHPI	GGTGA	4 cut(s)	111, 1070, 1139, 1187
AvaII	GGWCC	1 cut(s)	944
AvrII	CCTAGG	1 cut(s)	560
BaeI	ACNNNNGTAYC	2 cut(s)	831, 864
BanI	GGYRCC	1 cut(s)	572
BanII	GRGCYC	1 cut(s)	534
BauI	CACGAG	1 cut(s)	645
Bbv12I	GWGCWC	1 cut(s)	534
BbvCI	CCTCAGC	1 cut(s)	501
BbvI	GCAGC	8 cut(s)	125, 250, 607, 790, 823, 903, 1018, 1057
BccI	CCATC	5 cut(s)	146, 152, 215, 224, 928
BcgI	CGANNNNNNTGC	2 cut(s)	800, 834
BciT130I	CCWGG	1 cut(s)	948
BciVI	GTATCC	1 cut(s)	774
BcnI	CCSGG	1 cut(s)	153
BcoDI	GTCTC	3 cut(s)	26, 293, 653
BfaI	CTAG	3 cut(s)	561, 927, 1097
BfmI	CTRYAG	1 cut(s)	688
BfuI	GTATCC	1 cut(s)	774
BlnI	CCTAGG	1 cut(s)	560
BlpI	GCTNAGC	1 cut(s)	315
Bme1390I	CCNGG	2 cut(s)	153, 948
Bme18I	GGWCC	1 cut(s)	944
BmgT120I	GGNCC	2 cut(s)	167, 944
BmiI	GGNNCC	3 cut(s)	169, 574, 945
BmrFI	CCNGG	2 cut(s)	153, 948
BmsI	GCATC	5 cut(s)	316, 728, 903, 1078, 1151
BpmI	CTGGAG	3 cut(s)	300, 558, 1200
Bpu10I	CCTNAGC	1 cut(s)	501
Bpu1102I	GCTNAGC	1 cut(s)	315
BpuMI	CCSGG	1 cut(s)	153
Bsa29I	ATCGAT	1 cut(s)	219
BsaI	GGTCTC	1 cut(s)	293
BsaJI	CCNNGG	4 cut(s)	267, 415, 560, 756
Bsc4I	CCNNNNNNNGG	7 cut(s)	91, 92, 158, 222, 257, 395, 968
Bse1I	ACTGG	7 cut(s)	283, 400, 541, 904, 1129, 1147, 1217
Bse3DI	GCAATG	1 cut(s)	813
BseBI	CCWGG	1 cut(s)	948
BseCI	ATCGAT	1 cut(s)	219
BseDI	CCNNGG	4 cut(s)	267, 415, 560, 756
BseGI	GGATG	3 cut(s)	918, 1093, 1166
BseLI	CCNNNNNNNGG	7 cut(s)	91, 92, 158, 222, 257, 395, 968
BseMI	GCAATG	1 cut(s)	813
BseMII	CTCAG	3 cut(s)	431, 492, 1039
BseNI	ACTGG	7 cut(s)	283, 400, 541, 904, 1129, 1147, 1217
BseRI	GAGGAG	1 cut(s)	605
BseXI	GCAGC	8 cut(s)	125, 250, 607, 790, 823, 903, 1018, 1057
BshFI	GGCC	2 cut(s)	168, 445
BshNI	GGYRCC	1 cut(s)	572
BshVI	ATCGAT	1 cut(s)	219
BsiHKAI	GWGCWC	1 cut(s)	534
BsiSI	CCGG	1 cut(s)	153
BslI	CCNNNNNNNGG	7 cut(s)	91, 92, 158, 222, 257, 395, 968
BsmAI	GTCTC	3 cut(s)	26, 293, 653
BsnI	GGCC	2 cut(s)	168, 445
Bso31I	GGTCTC	1 cut(s)	293
Bsp1286I	GDGCHC	1 cut(s)	534
Bsp143I	GATC	3 cut(s)	99, 634, 823
Bsp1720I	GCTNAGC	1 cut(s)	315
BspACI	CCGC	4 cut(s)	9, 111, 210, 461
BspANI	GGCC	2 cut(s)	168, 445
BspCNI	CTCAG	3 cut(s)	432, 493, 1038
BspDI	ATCGAT	1 cut(s)	219
BspLI	GGNNCC	3 cut(s)	169, 574, 945
BspMAI	CTGCAG	1 cut(s)	692
BspPI	GGATC	2 cut(s)	107, 818
BspT107I	GGYRCC	1 cut(s)	572
BspTNI	GGTCTC	1 cut(s)	293
BsrBI	CCGCTC	1 cut(s)	11
BsrDI	GCAATG	1 cut(s)	813
BsrI	ACTGG	7 cut(s)	283, 400, 541, 904, 1129, 1147, 1217
BssECI	CCNNGG	4 cut(s)	267, 415, 560, 756
BssMI	GATC	3 cut(s)	99, 634, 823
BssSI	CACGAG	1 cut(s)	645
BssT1I	CCWWGG	4 cut(s)	267, 415, 560, 756
Bst2BI	CACGAG	1 cut(s)	645
Bst2UI	CCWGG	1 cut(s)	948
Bst4CI	ACNGT	4 cut(s)	454, 834, 1021, 1052
Bst6I	CTCTTC	2 cut(s)	482, 1173
BstC8I	GCNNGC	2 cut(s)	401, 447
BstDEI	CTNAG	4 cut(s)	315, 440, 501, 1025
BstF5I	GGATG	3 cut(s)	918, 1093, 1166
BstKTI	GATC	3 cut(s)	102, 637, 826
BstMAI	GTCTC	3 cut(s)	26, 293, 653
BstMBI	GATC	3 cut(s)	99, 634, 823
BstMWI	GCNNNNNNNGC	2 cut(s)	14, 650
BstNI	CCWGG	1 cut(s)	948
BstNSI	RCATGY	1 cut(s)	790
BstSCI	CCNGG	2 cut(s)	151, 946
BstSFI	CTRYAG	1 cut(s)	688
BstV1I	GCAGC	8 cut(s)	125, 250, 607, 790, 823, 903, 1018, 1057
Bsu15I	ATCGAT	1 cut(s)	219
BsuI	GTATCC	1 cut(s)	774
BsuRI	GGCC	2 cut(s)	168, 445
BsuTUI	ATCGAT	1 cut(s)	219
BtgZI	GCGATG	1 cut(s)	171
BtsCI	GGATG	3 cut(s)	918, 1093, 1166
BtsI	GCAGTG	1 cut(s)	697
BtsIMutI	CAGTG	4 cut(s)	534, 697, 1033, 1140
Cac8I	GCNNGC	2 cut(s)	401, 447
CaiI	CAGNNNCTG	1 cut(s)	395
Cfr13I	GGNCC	2 cut(s)	167, 944
ClaI	ATCGAT	1 cut(s)	219
CseI	GACGC	1 cut(s)	482
Csp6I	GTAC	3 cut(s)	248, 355, 1048
CviAII	CATG	3 cut(s)	745, 787, 968
CviQI	GTAC	3 cut(s)	248, 355, 1048
DdeI	CTNAG	4 cut(s)	315, 440, 501, 1025
DpnI	GATC	3 cut(s)	101, 636, 825
DpnII	GATC	3 cut(s)	99, 634, 823
DrdI	GACNNNNNNGTC	1 cut(s)	307
DseDI	GACNNNNNNGTC	1 cut(s)	307
Eam1104I	CTCTTC	2 cut(s)	482, 1173
EarI	CTCTTC	2 cut(s)	482, 1173
Ecl136II	GAGCTC	1 cut(s)	532
Eco130I	CCWWGG	4 cut(s)	267, 415, 560, 756
Eco147I	AGGCCT	1 cut(s)	445
Eco24I	GRGCYC	1 cut(s)	534
Eco31I	GGTCTC	1 cut(s)	293
Eco47I	GGWCC	1 cut(s)	944
Eco53kI	GAGCTC	1 cut(s)	532
Eco57I	CTGAAG	1 cut(s)	28
EcoICRI	GAGCTC	1 cut(s)	532
EcoO109I	RGGNCCY	1 cut(s)	944
EcoRII	CCWGG	1 cut(s)	946
EcoT14I	CCWWGG	4 cut(s)	267, 415, 560, 756
EcoT38I	GRGCYC	1 cut(s)	534
ErhI	CCWWGG	4 cut(s)	267, 415, 560, 756
FaeI	CATG	3 cut(s)	748, 790, 971
FatI	CATG	3 cut(s)	744, 786, 967
FokI	GGATG	3 cut(s)	925, 1100, 1173
FriOI	GRGCYC	1 cut(s)	534
FspBI	CTAG	3 cut(s)	561, 927, 1097
GsuI	CTGGAG	3 cut(s)	300, 558, 1200
HaeIII	GGCC	2 cut(s)	168, 445
HapII	CCGG	1 cut(s)	153
HgaI	GACGC	1 cut(s)	482
Hin1II	CATG	3 cut(s)	748, 790, 971
HincII	GTYRAC	2 cut(s)	511, 697
HindII	GTYRAC	2 cut(s)	511, 697
HinfI	GANTC	4 cut(s)	436, 741, 938, 1199
HpaII	CCGG	1 cut(s)	153
HphI	GGTGA	4 cut(s)	111, 1070, 1139, 1187
Hpy166II	GTNNAC	3 cut(s)	472, 511, 697
Hpy188I	TCNGA	7 cut(s)	325, 341, 441, 669, 828, 880, 1122
Hpy188III	TCNNGA	4 cut(s)	767, 821, 980, 1097
Hpy8I	GTNNAC	3 cut(s)	472, 511, 697
Hpy99I	CGWCG	1 cut(s)	188
HpyAV	CCTTC	2 cut(s)	52, 1221
HpyCH4III	ACNGT	4 cut(s)	454, 834, 1021, 1052
HpyCH4IV	ACGT	1 cut(s)	195
HpyCH4V	TGCA	8 cut(s)	329, 449, 653, 690, 806, 811, 1091, 1164
HpyF10VI	GCNNNNNNNGC	2 cut(s)	14, 650
HpyF3I	CTNAG	4 cut(s)	315, 440, 501, 1025
HpySE526I	ACGT	1 cut(s)	195
Hsp92II	CATG	3 cut(s)	748, 790, 971
Kzo9I	GATC	3 cut(s)	99, 634, 823
LmnI	GCTCC	6 cut(s)	16, 53, 113, 260, 341, 982
Lsp1109I	GCAGC	8 cut(s)	125, 250, 607, 790, 823, 903, 1018, 1057
LweI	GCATC	5 cut(s)	316, 728, 903, 1078, 1151
MaeI	CTAG	3 cut(s)	561, 927, 1097
MaeII	ACGT	1 cut(s)	195
MaeIII	GTNAC	2 cut(s)	847, 1127
MalI	GATC	3 cut(s)	101, 636, 825
MbiI	CCGCTC	1 cut(s)	11
MboI	GATC	3 cut(s)	99, 634, 823
MboII	GAAGA	5 cut(s)	254, 326, 499, 1073, 1190
MfeI	CAATTG	1 cut(s)	345
MhlI	GDGCHC	1 cut(s)	534
MluCI	AATT	4 cut(s)	345, 639, 1080, 1151
MmeI	TCCRAC	2 cut(s)	49, 693
MseI	TTAA	3 cut(s)	234, 405, 423
MslI	CAYNNNNRTG	1 cut(s)	789
MspI	CCGG	1 cut(s)	153
MspR9I	CCNGG	2 cut(s)	153, 948
MunI	CAATTG	1 cut(s)	345
MvaI	CCWGG	1 cut(s)	948
MwoI	GCNNNNNNNGC	2 cut(s)	14, 650
NciI	CCSGG	1 cut(s)	153
NdeII	GATC	3 cut(s)	99, 634, 823
NlaIII	CATG	3 cut(s)	748, 790, 971
NlaIV	GGNNCC	3 cut(s)	169, 574, 945
NmuCI	GTSAC	1 cut(s)	1127
NspI	RCATGY	1 cut(s)	790
PceI	AGGCCT	1 cut(s)	445
PciI	ACATGT	1 cut(s)	786
PcsI	WCGNNNNNNNCGW	3 cut(s)	192, 643, 848
PfeI	GAWTC	4 cut(s)	436, 741, 938, 1199
PflMI	CCANNNNNTGG	1 cut(s)	395
PfoI	TCCNGGA	1 cut(s)	946
PpuMI	RGGWCCY	1 cut(s)	944
PscI	ACATGT	1 cut(s)	786
Psp124BI	GAGCTC	1 cut(s)	534
Psp5II	RGGWCCY	1 cut(s)	944
Psp6I	CCWGG	1 cut(s)	946
PspGI	CCWGG	1 cut(s)	946
PspN4I	GGNNCC	3 cut(s)	169, 574, 945
PspPI	GGNCC	2 cut(s)	167, 944
PspPPI	RGGWCCY	1 cut(s)	944
PstI	CTGCAG	1 cut(s)	692
PstNI	CAGNNNCTG	1 cut(s)	395
RsaI	GTAC	3 cut(s)	249, 356, 1049
RsaNI	GTAC	3 cut(s)	248, 355, 1048
RseI	CAYNNNNRTG	1 cut(s)	789
SacI	GAGCTC	1 cut(s)	534
SaqAI	TTAA	3 cut(s)	234, 405, 423
Sau3AI	GATC	3 cut(s)	99, 634, 823
Sau96I	GGNCC	2 cut(s)	167, 944
ScrFI	CCNGG	2 cut(s)	153, 948
SduI	GDGCHC	1 cut(s)	534
SfaNI	GCATC	5 cut(s)	316, 728, 903, 1078, 1151
SfcI	CTRYAG	1 cut(s)	688
SinI	GGWCC	1 cut(s)	944
SmiMI	CAYNNNNRTG	1 cut(s)	789
Sse9I	AATT	4 cut(s)	345, 639, 1080, 1151
SseBI	AGGCCT	1 cut(s)	445
SsiI	CCGC	4 cut(s)	9, 111, 210, 461
SspMI	CTAG	3 cut(s)	561, 927, 1097
SstI	GAGCTC	1 cut(s)	534
StuI	AGGCCT	1 cut(s)	445
StyD4I	CCNGG	2 cut(s)	151, 946
StyI	CCWWGG	4 cut(s)	267, 415, 560, 756
TaaI	ACNGT	4 cut(s)	454, 834, 1021, 1052
TaiI	ACGT	1 cut(s)	198
TaqI	TCGA	2 cut(s)	219, 637
TasI	AATT	4 cut(s)	345, 639, 1080, 1151
TauI	GCSGC	3 cut(s)	11, 212, 463
TfiI	GAWTC	4 cut(s)	436, 741, 938, 1199
Tru1I	TTAA	3 cut(s)	234, 405, 423
Tru9I	TTAA	3 cut(s)	234, 405, 423
TscAI	CASTG	4 cut(s)	541, 697, 1033, 1147
TseFI	GTSAC	1 cut(s)	1127
TseI	GCWGC	9 cut(s)	5, 113, 263, 620, 803, 811, 916, 1031, 1070
Tsp45I	GTSAC	1 cut(s)	1127
TspDTI	ATGAA	3 cut(s)	255, 594, 972
TspGWI	ACGGA	1 cut(s)	172
TspRI	CASTG	4 cut(s)	541, 697, 1033, 1147
Van91I	CCANNNNNTGG	1 cut(s)	395
VpaK11BI	GGWCC	1 cut(s)	944
XbaI	TCTAGA	1 cut(s)	1096
XceI	RCATGY	1 cut(s)	790
XmaJI	CCTAGG	1 cut(s)	560
XspI	CTAG	3 cut(s)	561, 927, 1097

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.