RLG00000014420

ER-associated misfolded protein catabolic process

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
rosa_laevigata
Chr3
OG0004525
Physical Location & Seq
Forward (+)
52980863 .. 52983274
2412 bp
Loading structure...
UTR
Exon/CDS
Intron
RLM00000014420

Sequence Viewer

Length: 1068 bp
ATGACTTGTAAGGGCAAATCCAGTATCTTGTGTGGACGTCCTTTTGACTTTGCCCTCTCTGTCGGTGGGGAGTCCACAAAGCAAGTTCTTCTCTCTCTCGCATTCTCGCTCCAAATTCGCGGCATCTCATCGACCAAGGAGCAAGCGCTCGTGGGTTCCAAATACTCGGAAAGAAGGTTAATTGTTGAAAAATCAACTATCTGGACTTTGAAGCTCATGGATGGGGGTGATGGTGGTACTGGATTCACCTGCAACATTTGCTTTGAATCTGCTGATAAAGATCCAATTGTAACACCTTGTGGCCACCTTTACTGCAAGTCTTGTATATATACATGGCTTCATAACCCAAGACATGATTCCAAGAGGTGCCCTTGCCCTGTATGCAATGCTATTATAGAGGAGAGCAAACTGATTCCTCTGTATGGAATAGGAAAATCACAAGATTTAAATCAAAAGTCTCGGCCTATACCTGTAGCCAGTGTTAAGAGCCCAGAAAGGCAAGCTGGTCAAAAGTCTGCCACTACTTCAGCTCCATATAGGCCAACTCCTTCAGCTCCAGAGTGGCCGACTGTTCCAAGACATGCCACTCCTTCAGCTCCAGAGTGGCCGACTGTTCCAAGACATGCCACTCCTTCAGCTCCAGAGTGGCCAACTGATCCAACATACATTCCTTCGGCTCCTGAATGGCCGACTGGTCCAAGACCTGCCACTCCTTCAGCTCCCATATGGACTGATCCAAGACCTGCCACTCCTTCAGCTTCAAACTGTTCATCTGATCAAACACTTGCCACTCCTTCAACTGCCAATGTCATTCTGAACCAAGTTTGTAGGCTGTTAATACGTGTGGGACAGTACATGCTAGTGAGGATAATAGAAGTTGCCACAGATAAGCTCATTGAAGCTGTAGAAAGAAAAATCAATGAGTCGAGTGAGGCAGCAGAAGAGAGGAACGATGTTAATGAAGAAGGAAGTGGAAATAATACTGTATCAAGTGAGGAGGTGGAAGTGACGGATAGCGATGGAGAAGGAAGCCATCTGGGGCGCTGGGTTGTGCTCAACCCAACTTAG
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
ko04141 map04141
Pfam Domains
Protein Families
zf-C3HC4 zf-C3HC4_3 zf-RING_UBOX

Protein Analysis

356

Amino Acids

38.52

Weight (kDa)

6.13

Isoelectric Point (pI)

46.38

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
zf-C3HC4_3 PF13920 83 - 134 1.1e-06 Zinc finger, C3HC4 type (RING finger)
zf-RING_2 PF13639 83 - 129 1.4e-06 Ring finger domain
zf-RING_UBOX PF13445 84 - 124 5.1e-09 RING-type zinc-finger
zf-C3HC4 PF00097 84 - 128 4.3e-08 Zinc finger, C3HC4 type (RING finger)
zf-C3HC4_2 PF13923 84 - 124 4.7e-06 Zinc finger, C3HC4 type (RING finger)
zf-RING_5 PF14634 84 - 129 2.4e-06 zinc-RING finger domain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AarI CACCTGC 1 cut(s) 257
AatII GACGTC 1 cut(s) 40
Acc36I ACCTGC 3 cut(s) 257, 712, 751
AccB1I GGYRCC 1 cut(s) 366
AccII CGCG 1 cut(s) 120
AciI CCGC 1 cut(s) 120
AclWI GGATC 3 cut(s) 275, 650, 728
AcoI YGGCCR 5 cut(s) 301, 563, 605, 647, 686
AcsI RAATTY 1 cut(s) 114
AcuI CTGAAG 6 cut(s) 510, 534, 576, 618, 699, 738
AcyI GRCGYC 1 cut(s) 37
AdeI CACNNNGTG 1 cut(s) 299
AfaI GTAC 2 cut(s) 238, 854
AfeI AGCGCT 1 cut(s) 147
AfiI CCNNNNNNNGG 1 cut(s) 422
AflIII ACRYGT 1 cut(s) 841
AgsI TTSAA 6 cut(s) 188, 211, 266, 762, 798, 899
AjuI GAANNNNNNNTTGG 2 cut(s) 340, 372
Alw21I GWGCWC 1 cut(s) 1056
Alw26I GTCTC 1 cut(s) 462
AlwI GGATC 3 cut(s) 275, 650, 728
Aor51HI AGCGCT 1 cut(s) 147
AoxI GGCC 7 cut(s) 301, 461, 539, 563, 605, 647, 686
ApeKI GCWGC 1 cut(s) 935
ApoI RAATTY 1 cut(s) 114
AspLEI GCGC 2 cut(s) 148, 1044
AspS9I GGNCC 1 cut(s) 695
AsuHPI GGTGA 2 cut(s) 238, 239
AvaII GGWCC 1 cut(s) 695
BaeGI GKGCMC 1 cut(s) 371
BalI TGGCCA 2 cut(s) 303, 649
BanI GGYRCC 1 cut(s) 366
BanII GRGCYC 1 cut(s) 491
BauI CACGAG 1 cut(s) 149
Bbv12I GWGCWC 1 cut(s) 1056
BbvI GCAGC 1 cut(s) 947
BccI CCATC 4 cut(s) 215, 224, 1013, 1041
BclI TGATCA 1 cut(s) 775
BcoDI GTCTC 1 cut(s) 462
BfaI CTAG 1 cut(s) 860
BfmI CTRYAG 2 cut(s) 471, 903
BfoI RGCGCY 2 cut(s) 149, 1045
BfuAI ACCTGC 3 cut(s) 257, 712, 751
BisI GCNGC 2 cut(s) 121, 936
BlsI GCNGC 2 cut(s) 122, 937
Bme18I GGWCC 1 cut(s) 695
BmgT120I GGNCC 1 cut(s) 695
BmiI GGNNCC 3 cut(s) 157, 368, 678
BmsI GCATC 1 cut(s) 132
BpmI CTGGAG 3 cut(s) 540, 582, 624
BsaAI YACGTR 1 cut(s) 842
BsaBI GATNNNNATC 2 cut(s) 279, 447
BsaHI GRCGYC 1 cut(s) 37
BsaJI CCNNGG 1 cut(s) 135
BsaXI ACNNNNNCTCC 2 cut(s) 514, 544
Bsc4I CCNNNNNNNGG 1 cut(s) 422
Bse1I ACTGG 4 cut(s) 21, 244, 477, 697
Bse3DI GCAATG 1 cut(s) 391
Bse8I GATNNNNATC 2 cut(s) 279, 447
BseDI CCNNGG 1 cut(s) 135
BseGI GGATG 1 cut(s) 226
BseJI GATNNNNATC 2 cut(s) 279, 447
BseLI CCNNNNNNNGG 1 cut(s) 422
BseMI GCAATG 1 cut(s) 391
BseNI ACTGG 4 cut(s) 21, 244, 477, 697
BseRI GAGGAG 2 cut(s) 413, 1010
BseSI GKGCMC 1 cut(s) 371
BseXI GCAGC 1 cut(s) 947
BseYI CCCAGC 1 cut(s) 1044
Bsh1236I CGCG 1 cut(s) 120
BshFI GGCC 7 cut(s) 303, 463, 541, 565, 607, 649, 688
BshNI GGYRCC 1 cut(s) 366
BsiHKAI GWGCWC 1 cut(s) 1056
BslFI GGGAC 1 cut(s) 861
BslI CCNNNNNNNGG 1 cut(s) 422
BsmAI GTCTC 1 cut(s) 462
BsmFI GGGAC 1 cut(s) 861
BsmI GAATGC 1 cut(s) 101
BsnI GGCC 7 cut(s) 303, 463, 541, 565, 607, 649, 688
Bsp1286I GDGCHC 3 cut(s) 371, 491, 1056
Bsp143I GATC 4 cut(s) 280, 655, 733, 775
BspACI CCGC 1 cut(s) 120
BspANI GGCC 7 cut(s) 303, 463, 541, 565, 607, 649, 688
BspFNI CGCG 1 cut(s) 120
BspLI GGNNCC 3 cut(s) 157, 368, 678
BspMI ACCTGC 3 cut(s) 257, 712, 751
BspPI GGATC 3 cut(s) 275, 650, 728
BspT107I GGYRCC 1 cut(s) 366
BsrDI GCAATG 1 cut(s) 391
BsrI ACTGG 4 cut(s) 21, 244, 477, 697
BssECI CCNNGG 1 cut(s) 135
BssMI GATC 4 cut(s) 280, 655, 733, 775
BssNI GRCGYC 1 cut(s) 37
BssSI CACGAG 1 cut(s) 149
BssT1I CCWWGG 1 cut(s) 135
Bst2BI CACGAG 1 cut(s) 149
Bst4CI ACNGT 5 cut(s) 571, 613, 767, 852, 985
Bst6I CTCTTC 1 cut(s) 936
BstACI GRCGYC 1 cut(s) 37
BstAPI GCANNNNNTGC 1 cut(s) 258
BstBAI YACGTR 1 cut(s) 842
BstC8I GCNNGC 2 cut(s) 144, 501
BstDEI CTNAG 1 cut(s) 1065
BstF5I GGATG 1 cut(s) 226
BstFNI CGCG 1 cut(s) 120
BstH2I RGCGCY 2 cut(s) 149, 1045
BstHHI GCGC 2 cut(s) 148, 1044
BstKTI GATC 4 cut(s) 283, 658, 736, 778
BstMAI GTCTC 1 cut(s) 462
BstMBI GATC 4 cut(s) 280, 655, 733, 775
BstMWI GCNNNNNNNGC 2 cut(s) 258, 381
BstNSI RCATGY 3 cut(s) 584, 626, 859
BstSFI CTRYAG 2 cut(s) 471, 903
BstSLI GKGCMC 1 cut(s) 371
BstUI CGCG 1 cut(s) 120
BstV1I GCAGC 1 cut(s) 947
BstX2I RGATCY 1 cut(s) 280
BstYI RGATCY 1 cut(s) 280
BsuRI GGCC 7 cut(s) 303, 463, 541, 565, 607, 649, 688
BtgZI GCGATG 1 cut(s) 1032
BtsCI GGATG 1 cut(s) 226
BtsIMutI CAGTG 1 cut(s) 484
BveI ACCTGC 3 cut(s) 257, 712, 751
Cac8I GCNNGC 2 cut(s) 144, 501
CfoI GCGC 2 cut(s) 148, 1044
Cfr13I GGNCC 1 cut(s) 695
Csp6I GTAC 2 cut(s) 237, 853
CviAII CATG 6 cut(s) 217, 333, 353, 581, 623, 856
CviQI GTAC 2 cut(s) 237, 853
DdeI CTNAG 1 cut(s) 1065
DpnI GATC 4 cut(s) 282, 657, 735, 777
DpnII GATC 4 cut(s) 280, 655, 733, 775
DraI TTTAAA 1 cut(s) 447
DraIII CACNNNGTG 1 cut(s) 299
EaeI YGGCCR 5 cut(s) 301, 563, 605, 647, 686
Eam1104I CTCTTC 1 cut(s) 936
EarI CTCTTC 1 cut(s) 936
Eco130I CCWWGG 1 cut(s) 135
Eco24I GRGCYC 1 cut(s) 491
Eco47I GGWCC 1 cut(s) 695
Eco47III AGCGCT 1 cut(s) 147
Eco57I CTGAAG 6 cut(s) 510, 534, 576, 618, 699, 738
EcoT14I CCWWGG 1 cut(s) 135
EcoT38I GRGCYC 1 cut(s) 491
ErhI CCWWGG 1 cut(s) 135
FaeI CATG 6 cut(s) 220, 336, 356, 584, 626, 859
FaqI GGGAC 1 cut(s) 861
FatI CATG 6 cut(s) 216, 332, 352, 580, 622, 855
FauNDI CATATG 1 cut(s) 725
FbaI TGATCA 1 cut(s) 775
Fnu4HI GCNGC 2 cut(s) 121, 936
FokI GGATG 1 cut(s) 233
FriOI GRGCYC 1 cut(s) 491
Fsp4HI GCNGC 2 cut(s) 121, 936
FspBI CTAG 1 cut(s) 860
GlaI GCGC 2 cut(s) 147, 1043
GluI GCNGC 2 cut(s) 121, 936
GsaI CCCAGC 1 cut(s) 1048
GsuI CTGGAG 3 cut(s) 540, 582, 624
HaeII RGCGCY 2 cut(s) 149, 1045
HaeIII GGCC 7 cut(s) 303, 463, 541, 565, 607, 649, 688
HhaI GCGC 2 cut(s) 148, 1044
Hin1I GRCGYC 1 cut(s) 37
Hin1II CATG 6 cut(s) 220, 336, 356, 584, 626, 859
Hin6I GCGC 2 cut(s) 146, 1042
HinP1I GCGC 2 cut(s) 146, 1042
HinfI GANTC 6 cut(s) 71, 243, 266, 356, 412, 923
HphI GGTGA 2 cut(s) 238, 239
Hpy166II GTNNAC 2 cut(s) 35, 75
Hpy188I TCNGA 3 cut(s) 169, 775, 816
Hpy188III TCNNGA 5 cut(s) 202, 557, 599, 641, 680
Hpy8I GTNNAC 2 cut(s) 35, 75
HpyCH4III ACNGT 5 cut(s) 571, 613, 767, 852, 985
HpyCH4IV ACGT 2 cut(s) 37, 841
HpyCH4V TGCA 3 cut(s) 252, 315, 384
HpyF10VI GCNNNNNNNGC 2 cut(s) 258, 381
HpyF3I CTNAG 1 cut(s) 1065
HpySE526I ACGT 2 cut(s) 37, 841
Hsp92I GRCGYC 1 cut(s) 37
Hsp92II CATG 6 cut(s) 220, 336, 356, 584, 626, 859
HspAI GCGC 2 cut(s) 146, 1042
Ksp22I TGATCA 1 cut(s) 775
Kzo9I GATC 4 cut(s) 280, 655, 733, 775
LmnI GCTCC 8 cut(s) 114, 139, 535, 559, 601, 643, 682, 724
Lsp1109I GCAGC 1 cut(s) 947
LweI GCATC 1 cut(s) 132
MaeI CTAG 1 cut(s) 860
MaeII ACGT 2 cut(s) 37, 841
MaeIII GTNAC 2 cut(s) 289, 1006
MalI GATC 4 cut(s) 282, 657, 735, 777
MboI GATC 4 cut(s) 280, 655, 733, 775
MboII GAAGA 3 cut(s) 80, 953, 974
MfeI CAATTG 1 cut(s) 285
MflI RGATCY 1 cut(s) 280
MhlI GDGCHC 3 cut(s) 371, 491, 1056
MlsI TGGCCA 2 cut(s) 303, 649
MluCI AATT 3 cut(s) 114, 180, 285
MluNI TGGCCA 2 cut(s) 303, 649
MlyI GAGTC 2 cut(s) 80, 932
MmeI TCCRAC 1 cut(s) 683
MnlI CCTC 9 cut(s) 65, 357, 391, 426, 858, 925, 939, 988, 991
Mox20I TGGCCA 2 cut(s) 303, 649
MscI TGGCCA 2 cut(s) 303, 649
MseI TTAA 5 cut(s) 179, 446, 483, 836, 957
MslI CAYNNNNRTG 1 cut(s) 860
Msp20I TGGCCA 2 cut(s) 303, 649
MunI CAATTG 1 cut(s) 285
Mva1269I GAATGC 1 cut(s) 101
MvnI CGCG 1 cut(s) 120
MwoI GCNNNNNNNGC 2 cut(s) 258, 381
NdeI CATATG 1 cut(s) 725
NdeII GATC 4 cut(s) 280, 655, 733, 775
NlaIII CATG 6 cut(s) 220, 336, 356, 584, 626, 859
NlaIV GGNNCC 3 cut(s) 157, 368, 678
NmeAIII GCCGAG 1 cut(s) 439
NmuCI GTSAC 1 cut(s) 1006
NspI RCATGY 3 cut(s) 584, 626, 859
PaqCI CACCTGC 1 cut(s) 257
PctI GAATGC 1 cut(s) 101
PfeI GAWTC 4 cut(s) 243, 266, 356, 412
PkrI GCNGC 2 cut(s) 122, 937
PleI GAGTC 2 cut(s) 79, 931
PpsI GAGTC 2 cut(s) 79, 931
Ppu21I YACGTR 1 cut(s) 842
PspFI CCCAGC 1 cut(s) 1044
PspN4I GGNNCC 3 cut(s) 157, 368, 678
PspPI GGNCC 1 cut(s) 695
PsuI RGATCY 1 cut(s) 280
RsaI GTAC 2 cut(s) 238, 854
RsaNI GTAC 2 cut(s) 237, 853
RseI CAYNNNNRTG 1 cut(s) 860
SaqAI TTAA 5 cut(s) 179, 446, 483, 836, 957
SatI GCNGC 2 cut(s) 121, 936
Sau3AI GATC 4 cut(s) 280, 655, 733, 775
Sau96I GGNCC 1 cut(s) 695
SchI GAGTC 2 cut(s) 80, 932
SduI GDGCHC 3 cut(s) 371, 491, 1056
SfaNI GCATC 1 cut(s) 132
SfcI CTRYAG 2 cut(s) 471, 903
SinI GGWCC 1 cut(s) 695
SmiI ATTTAAAT 1 cut(s) 447
SmiMI CAYNNNNRTG 1 cut(s) 860
Sse9I AATT 3 cut(s) 114, 180, 285
SsiI CCGC 1 cut(s) 120
SspMI CTAG 1 cut(s) 860
StyI CCWWGG 1 cut(s) 135
SwaI ATTTAAAT 1 cut(s) 447
TaaI ACNGT 5 cut(s) 571, 613, 767, 852, 985
TaiI ACGT 2 cut(s) 40, 844
TaqI TCGA 2 cut(s) 131, 926
TasI AATT 3 cut(s) 114, 180, 285
TatI WGTACW 1 cut(s) 852
TauI GCSGC 1 cut(s) 123
TfiI GAWTC 4 cut(s) 243, 266, 356, 412
Tru1I TTAA 5 cut(s) 179, 446, 483, 836, 957
Tru9I TTAA 5 cut(s) 179, 446, 483, 836, 957
TscAI CASTG 1 cut(s) 484
TseFI GTSAC 1 cut(s) 1006
TseI GCWGC 1 cut(s) 935
Tsp45I GTSAC 1 cut(s) 1006
TspDTI ATGAA 3 cut(s) 329, 759, 975
TspGWI ACGGA 1 cut(s) 1025
TspRI CASTG 1 cut(s) 484
VpaK11BI GGWCC 1 cut(s) 695
XapI RAATTY 1 cut(s) 114
XceI RCATGY 3 cut(s) 584, 626, 859
XspI CTAG 1 cut(s) 860
ZraI GACGTC 1 cut(s) 38
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.