Basic Information

Type: gene

Biological Identity

Species

malus_domestica

Chromosome

Chr12

Orthogroup ID

OG0006291

Physical Location & Seq

Genomic Coordinates Forward (+)

17892653 .. 17895805

Gene Structure 3153 bp

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UTR

Exon/CDS

Intron

Transcript / Protein ID

MD12G1113000.v1.1.491

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1086 bp

ATGGGTGAGAAAAAGGAATCCCCGAAGAATGACGGTGAGAAGAAGCCCACCGACGCCGCCCCCAAGAAGGACGACGGTCTGAACATCTTCATTTTCAAGACCGACATCCATTGCGAGGGATGTGCTAAGAAAATCAAACGGGCTGTCAAGAATTTTGAAGGCGTTGAACAAGTGAAGACGGATAGTGCAGCCAACAAATTGACTGTAACTGGGAAAGTTGATCCCGCCGGACTCAAGGAGAAGCTCGAGCAGAAGATCAAGAAGAAGGTCGACCTGGTTTCTCCTCAGCCCAAAAAAGATGGTGGCGGTGGCGGTGGTGGAGACAAGAAGCCTGCCGCAGATGGAAAGGCTGAGAAAAAGGGTGAAGAGAAAAAGCCAGCTGATAACAAAAAGCCAGCGGATGACAAGAAGGCAGCTGAAGACAAAAAGGCCAAAGAGGCACCCAAAGAGAGTGCTGTGGTGTTGAAGATCAGATTGCATTGTGATGGTTGCATGCAGAAGATGAAGAGTAAAATCTCCAAGTTTAAAGGTGTTAACAATGTGAGCTTTGACGCATCCAAGGACCTAGTAACGGTGAAGGGCTTCATGGACGTAAAGGAACTAGTACCTTACCTCAAGGAGAAGTTCCGGAGGGCCGTGGAAGTGGTCCCACCCAAGAAAGATGACAGCGGAGCCGCCGACAAGAAACCAAAAGACGGCGGCGGGGACAAGAAGGAAAAAGAAGGTGCAGGAGGTGATAAGAAGGAGAAAGAAGGAGGTGGTGAGAAGAAAGATAAAGCAGTCGCAGCAGGCGACGGAGAAAAGAAAGAAGTTGTCGCGGCCGCAGGCGGCGGAGGAGGAGGAGGCGCCCCGAAGATGGAGATGAGCAAGATGGAATATAATGGGTACCCTTACCCACCTCCTTCTTACTATTGGTACGACGAAGGGCACGTTTACAACCACAACAAGTTTGTAATGGAGGCTCAAGCGCACCAAGCGCACATTAGCCAAGGGTCGTCTAGCCACGGCTACGCCGTGCCGATGGAACACTACCCTGCGCCGCAGATGTTCAGCGACGAAAATCCAAACGGTTGTTCGGTGATGTAG

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0003674 GO:0005488 GO:0005507 GO:0005575 GO:0005622 GO:0005623 GO:0005737 GO:0006810 GO:0006811 GO:0006812 GO:0006873 GO:0006875 GO:0008150 GO:0009987 GO:0019725 GO:0030001 GO:0030003 GO:0042592 GO:0043167 GO:0043169 GO:0044424 GO:0044464 GO:0046872 GO:0046914 GO:0046916 GO:0048878 GO:0050801 GO:0051179 GO:0051234 GO:0055065 GO:0055076 GO:0055080 GO:0055082 GO:0065007 GO:0065008 GO:0098771

KEGG Pathways

Metabolic & Signaling

No pathways identified.

Pfam Domains

Protein Families

HMA

Protein Analysis

362

Amino Acids

38.87

Weight (kDa)

9.12

Isoelectric Point (pI)

35.89

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
HMA	PF00403	33 - 88	1.8e-14	Heavy-metal-associated domain
HMA	PF00403	156 - 212	7.2e-09	Heavy-metal-associated domain

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

Style Settings

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

iTOL Interactive Tree Of Life · Most popular EvolView Flexible annotations MEGA Desktop phylogenetics suite FigTree Desktop tree editor

Orthologous Genes (Group: OG0006291)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT2G36950 AT5G03380 AT5G03380
fragaria_vesca	FvH4_6g16410 FvH4_6g16410
malus_domestica	MD04G1093300.v1.1 MD12G1113000.v1.1
prunus_persica	Prupe.6G232100_v2.0.a1 Prupe.6G232100_v2.0.a1
pyrus_communis	pycom04g08830 pycom12g11200
rosa_chinensis	RchiOBHm_Chr3g0470271
rosa_laevigata	RLG00000024284 RLG00000024290
rosa_multiflora	Rmu_co8443661.1_g000001 Rmu_sc0005600.1_g000019 Rmu_sc0011073.1_g000002
rosa_roxburghii	Rroxscaffold_6G00411000 Rroxscaffold_6G00411110
rosa_rugosa	Rorug03G0107700
rosa_samantha	Rh1AG099300 Rh3AG157500 Rh3BG181600 Rh3CG172400 Rh3DG193300
rosa_wichuraiana	Rw3G014860 Rw3G014980

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
Acc65I	GGTACC	1 cut(s)	885
AccB1I	GGYRCC	3 cut(s)	439, 845, 885
AccI	GTMKAC	1 cut(s)	270
AccII	CGCG	1 cut(s)	818
AccIII	TCCGGA	1 cut(s)	627
AclWI	GGATC	1 cut(s)	215
AcoI	YGGCCR	1 cut(s)	819
AcsI	RAATTY	1 cut(s)	151
AcuI	CTGAAG	1 cut(s)	438
AcyI	GRCGYC	2 cut(s)	54, 846
AfaI	GTAC	3 cut(s)	606, 887, 917
AfiI	CCNNNNNNNGG	5 cut(s)	67, 115, 571, 695, 856
AgsI	TTSAA	4 cut(s)	97, 158, 167, 466
AhlI	ACTAGT	1 cut(s)	601
AjnI	CCWGG	1 cut(s)	273
AjuI	GAANNNNNNNTTGG	1 cut(s)	1057
AluBI	AGCT	4 cut(s)	244, 380, 416, 546
AluI	AGCT	4 cut(s)	244, 380, 416, 546
Alw26I	GTCTC	1 cut(s)	315
AlwI	GGATC	1 cut(s)	215
Ama87I	CYCGRG	1 cut(s)	245
Aor13HI	TCCGGA	1 cut(s)	627
AoxI	GGCC	3 cut(s)	429, 633, 819
ApeKI	GCWGC	3 cut(s)	188, 413, 785
ApoI	RAATTY	1 cut(s)	151
ArsI	GACNNNNNNTTYG	2 cut(s)	129, 161
Asp700I	GAANNNNTTC	2 cut(s)	86, 581
Asp718I	GGTACC	1 cut(s)	885
AspLEI	GCGC	4 cut(s)	848, 970, 979, 1039
AspS9I	GGNCC	3 cut(s)	562, 633, 646
AsuHPI	GGTGA	6 cut(s)	17, 47, 374, 586, 746, 773
AvaI	CYCGRG	1 cut(s)	245
AvaII	GGWCC	2 cut(s)	562, 646
BaeGI	GKGCMC	1 cut(s)	930
BanI	GGYRCC	3 cut(s)	439, 845, 885
BbsI	GAAGAC	2 cut(s)	182, 426
BbvCI	CCTCAGC	1 cut(s)	285
BbvI	GCAGC	3 cut(s)	200, 425, 797
BccI	CCATC	6 cut(s)	293, 335, 479, 850, 865, 1015
BceAI	ACGGC	4 cut(s)	620, 712, 998, 1021
BcgI	CGANNNNNNTGC	2 cut(s)	104, 138
BciT130I	CCWGG	1 cut(s)	275
BcoDI	GTCTC	1 cut(s)	315
BcuI	ACTAGT	1 cut(s)	601
BfaI	CTAG	3 cut(s)	566, 602, 999
BfoI	RGCGCY	1 cut(s)	849
BglI	GCCNNNNNGGC	1 cut(s)	437
Bme1390I	CCNGG	1 cut(s)	275
Bme18I	GGWCC	2 cut(s)	562, 646
BmeT110I	CYCGRG	1 cut(s)	245
BmgT120I	GGNCC	3 cut(s)	562, 633, 646
BmiI	GGNNCC	5 cut(s)	441, 648, 673, 847, 887
BmrFI	CCNGG	1 cut(s)	275
BmrI	ACTGGG	1 cut(s)	219
BmsI	GCATC	1 cut(s)	563
BmuI	ACTGGG	1 cut(s)	219
BoxI	GACNNNNGTC	1 cut(s)	75
BpiI	GAAGAC	2 cut(s)	182, 426
Bpu10I	CCTNAGC	1 cut(s)	285
BpuEI	CTTGAG	3 cut(s)	218, 599, 948
BsaHI	GRCGYC	2 cut(s)	54, 846
BsaJI	CCNNGG	4 cut(s)	558, 636, 988, 1003
BsaWI	WCCGGW	1 cut(s)	627
Bsc4I	CCNNNNNNNGG	5 cut(s)	67, 115, 571, 695, 856
Bse1I	ACTGG	1 cut(s)	214
Bse3DI	GCAATG	1 cut(s)	109
BseAI	TCCGGA	1 cut(s)	627
BseBI	CCWGG	1 cut(s)	275
BseDI	CCNNGG	4 cut(s)	558, 636, 988, 1003
BseGI	GGATG	4 cut(s)	105, 125, 406, 554
BseLI	CCNNNNNNNGG	5 cut(s)	67, 115, 571, 695, 856
BseMI	GCAATG	1 cut(s)	109
BseMII	CTCAG	2 cut(s)	299, 342
BseNI	ACTGG	1 cut(s)	214
BseRI	GAGGAG	4 cut(s)	273, 849, 852, 855
BseSI	GKGCMC	1 cut(s)	930
BseX3I	CGGCCG	1 cut(s)	819
BseXI	GCAGC	3 cut(s)	200, 425, 797
BsgI	GTGCAG	2 cut(s)	207, 747
Bsh1236I	CGCG	1 cut(s)	818
Bsh1285I	CGRYCG	1 cut(s)	822
BshFI	GGCC	3 cut(s)	431, 635, 821
BshNI	GGYRCC	3 cut(s)	439, 845, 885
BsiEI	CGRYCG	1 cut(s)	822
BsiHKCI	CYCGRG	1 cut(s)	245
BsiSI	CCGG	2 cut(s)	228, 628
BslFI	GGGAC	2 cut(s)	632, 719
BslI	CCNNNNNNNGG	5 cut(s)	67, 115, 571, 695, 856
BsmAI	GTCTC	1 cut(s)	315
BsmFI	GGGAC	2 cut(s)	632, 719
BsnI	GGCC	3 cut(s)	431, 635, 821
BsoBI	CYCGRG	1 cut(s)	245
Bsp1286I	GDGCHC	1 cut(s)	930
Bsp13I	TCCGGA	1 cut(s)	627
Bsp143I	GATC	3 cut(s)	220, 255, 468
BspANI	GGCC	3 cut(s)	431, 635, 821
BspCNI	CTCAG	2 cut(s)	298, 343
BspEI	TCCGGA	1 cut(s)	627
BspFNI	CGCG	1 cut(s)	818
BspLI	GGNNCC	5 cut(s)	441, 648, 673, 847, 887
BspPI	GGATC	1 cut(s)	215
BspT107I	GGYRCC	3 cut(s)	439, 845, 885
BsrDI	GCAATG	1 cut(s)	109
BsrI	ACTGG	1 cut(s)	214
BssECI	CCNNGG	4 cut(s)	558, 636, 988, 1003
BssMI	GATC	3 cut(s)	220, 255, 468
BssNI	GRCGYC	2 cut(s)	54, 846
BssT1I	CCWWGG	2 cut(s)	558, 988
Bst2UI	CCWGG	1 cut(s)	275
Bst4CI	ACNGT	5 cut(s)	35, 77, 205, 574, 1070
Bst6I	CTCTTC	2 cut(s)	360, 500
BstACI	GRCGYC	2 cut(s)	54, 846
BstC8I	GCNNGC	6 cut(s)	333, 378, 396, 494, 790, 826
BstDEI	CTNAG	3 cut(s)	126, 285, 351
BstDSI	CCRYGG	2 cut(s)	636, 1003
BstF5I	GGATG	4 cut(s)	105, 125, 406, 554
BstFNI	CGCG	1 cut(s)	818
BstH2I	RGCGCY	1 cut(s)	849
BstHHI	GCGC	4 cut(s)	848, 970, 979, 1039
BstKTI	GATC	3 cut(s)	223, 258, 471
BstMAI	GTCTC	1 cut(s)	315
BstMBI	GATC	3 cut(s)	220, 255, 468
BstMCI	CGRYCG	1 cut(s)	822
BstMWI	GCNNNNNNNGC	4 cut(s)	437, 785, 974, 976
BstNI	CCWGG	1 cut(s)	275
BstNSI	RCATGY	1 cut(s)	496
BstPAI	GACNNNNGTC	1 cut(s)	75
BstSCI	CCNGG	1 cut(s)	273
BstSLI	GKGCMC	1 cut(s)	930
BstUI	CGCG	1 cut(s)	818
BstV1I	GCAGC	3 cut(s)	200, 425, 797
BstV2I	GAAGAC	2 cut(s)	182, 426
BstZI	CGGCCG	1 cut(s)	819
BsuRI	GGCC	3 cut(s)	431, 635, 821
BtgI	CCRYGG	2 cut(s)	636, 1003
BtsCI	GGATG	4 cut(s)	105, 125, 406, 554
Cac8I	GCNNGC	6 cut(s)	333, 378, 396, 494, 790, 826
CciNI	GCGGCCGC	1 cut(s)	819
CfoI	GCGC	4 cut(s)	848, 970, 979, 1039
Cfr13I	GGNCC	3 cut(s)	562, 633, 646
CseI	GACGC	2 cut(s)	62, 560
CsiI	ACCWGGT	1 cut(s)	273
Csp6I	GTAC	3 cut(s)	605, 886, 916
CviAII	CATG	2 cut(s)	493, 586
CviQI	GTAC	3 cut(s)	605, 886, 916
DdeI	CTNAG	3 cut(s)	126, 285, 351
DinI	GGCGCC	1 cut(s)	847
DpnI	GATC	3 cut(s)	222, 257, 470
DpnII	GATC	3 cut(s)	220, 255, 468
DraI	TTTAAA	1 cut(s)	526
EaeI	YGGCCR	1 cut(s)	819
EagI	CGGCCG	1 cut(s)	819
Eam1104I	CTCTTC	2 cut(s)	360, 500
EarI	CTCTTC	2 cut(s)	360, 500
EciI	GGCGGA	1 cut(s)	846
EclXI	CGGCCG	1 cut(s)	819
Eco130I	CCWWGG	2 cut(s)	558, 988
Eco47I	GGWCC	2 cut(s)	562, 646
Eco52I	CGGCCG	1 cut(s)	819
Eco57I	CTGAAG	1 cut(s)	438
Eco88I	CYCGRG	1 cut(s)	245
EcoO109I	RGGNCCY	1 cut(s)	562
EcoRII	CCWGG	1 cut(s)	273
EcoT14I	CCWWGG	2 cut(s)	558, 988
EgeI	GGCGCC	1 cut(s)	847
EheI	GGCGCC	1 cut(s)	847
ErhI	CCWWGG	2 cut(s)	558, 988
FaeI	CATG	2 cut(s)	496, 589
FaiI	YATR	3 cut(s)	494, 587, 879
FaqI	GGGAC	2 cut(s)	632, 719
FatI	CATG	2 cut(s)	492, 585
FauI	CCCGC	2 cut(s)	232, 695
FblI	GTMKAC	1 cut(s)	270
FokI	GGATG	4 cut(s)	92, 132, 413, 541
FspBI	CTAG	3 cut(s)	566, 602, 999
GlaI	GCGC	4 cut(s)	847, 969, 978, 1038
HaeII	RGCGCY	1 cut(s)	849
HaeIII	GGCC	3 cut(s)	431, 635, 821
HapII	CCGG	2 cut(s)	228, 628
HgaI	GACGC	2 cut(s)	62, 560
HhaI	GCGC	4 cut(s)	848, 970, 979, 1039
Hin1I	GRCGYC	2 cut(s)	54, 846
Hin1II	CATG	2 cut(s)	496, 589
Hin6I	GCGC	4 cut(s)	846, 968, 977, 1037
HinP1I	GCGC	4 cut(s)	846, 968, 977, 1037
HincII	GTYRAC	2 cut(s)	271, 535
HindII	GTYRAC	2 cut(s)	271, 535
HinfI	GANTC	2 cut(s)	17, 231
HpaI	GTTAAC	1 cut(s)	535
HpaII	CCGG	2 cut(s)	228, 628
HphI	GGTGA	6 cut(s)	17, 47, 374, 586, 746, 773
Hpy166II	GTNNAC	3 cut(s)	271, 535, 934
Hpy188I	TCNGA	2 cut(s)	81, 473
Hpy188III	TCNNGA	4 cut(s)	97, 148, 259, 628
Hpy8I	GTNNAC	3 cut(s)	271, 535, 934
Hpy99I	CGWCG	5 cut(s)	56, 77, 797, 923, 1058
HpyCH4III	ACNGT	5 cut(s)	35, 77, 205, 574, 1070
HpyCH4IV	ACGT	2 cut(s)	591, 930
HpyCH4V	TGCA	5 cut(s)	188, 478, 492, 496, 728
HpyF10VI	GCNNNNNNNGC	4 cut(s)	437, 785, 974, 976
HpyF3I	CTNAG	3 cut(s)	126, 285, 351
HpySE526I	ACGT	2 cut(s)	591, 930
Hsp92I	GRCGYC	2 cut(s)	54, 846
Hsp92II	CATG	2 cut(s)	496, 589
HspAI	GCGC	4 cut(s)	846, 968, 977, 1037
KasI	GGCGCC	1 cut(s)	845
Kpn2I	TCCGGA	1 cut(s)	627
KpnI	GGTACC	1 cut(s)	889
KspAI	GTTAAC	1 cut(s)	535
Kzo9I	GATC	3 cut(s)	220, 255, 468
LmnI	GCTCC	1 cut(s)	671
Lsp1109I	GCAGC	3 cut(s)	200, 425, 797
LweI	GCATC	1 cut(s)	563
MabI	ACCWGGT	1 cut(s)	273
MaeI	CTAG	3 cut(s)	566, 602, 999
MaeII	ACGT	2 cut(s)	591, 930
MaeIII	GTNAC	2 cut(s)	205, 568
MalI	GATC	3 cut(s)	222, 257, 470
MboI	GATC	3 cut(s)	220, 255, 468
MhlI	GDGCHC	1 cut(s)	930
MluCI	AATT	2 cut(s)	151, 197
Mly113I	GGCGCC	1 cut(s)	846
MlyI	GAGTC	1 cut(s)	225
MroI	TCCGGA	1 cut(s)	627
MroXI	GAANNNNTTC	2 cut(s)	86, 581
MseI	TTAA	2 cut(s)	525, 534
MslI	CAYNNNNRTG	1 cut(s)	483
MspA1I	CMGCKG	4 cut(s)	380, 398, 416, 669
MspI	CCGG	2 cut(s)	228, 628
MspR9I	CCNGG	1 cut(s)	275
MvaI	CCWGG	1 cut(s)	275
MvnI	CGCG	1 cut(s)	818
MwoI	GCNNNNNNNGC	4 cut(s)	437, 785, 974, 976
NarI	GGCGCC	1 cut(s)	846
NdeII	GATC	3 cut(s)	220, 255, 468
NlaIII	CATG	2 cut(s)	496, 589
NlaIV	GGNNCC	5 cut(s)	441, 648, 673, 847, 887
NotI	GCGGCCGC	1 cut(s)	819
NspI	RCATGY	1 cut(s)	496
PaeI	GCATGC	1 cut(s)	496
PaeR7I	CTCGAG	1 cut(s)	245
PcsI	WCGNNNNNNNCGW	3 cut(s)	789, 927, 1011
PdmI	GAANNNNTTC	2 cut(s)	86, 581
PfeI	GAWTC	1 cut(s)	17
PleI	GAGTC	1 cut(s)	225
PluTI	GGCGCC	1 cut(s)	849
PpsI	GAGTC	1 cut(s)	225
PpuMI	RGGWCCY	1 cut(s)	562
PshAI	GACNNNNGTC	1 cut(s)	75
Psp5II	RGGWCCY	1 cut(s)	562
Psp6I	CCWGG	1 cut(s)	273
PspGI	CCWGG	1 cut(s)	273
PspN4I	GGNNCC	5 cut(s)	441, 648, 673, 847, 887
PspPI	GGNCC	3 cut(s)	562, 633, 646
PspPPI	RGGWCCY	1 cut(s)	562
PspXI	VCTCGAGB	1 cut(s)	245
PvuII	CAGCTG	2 cut(s)	380, 416
RsaI	GTAC	3 cut(s)	606, 887, 917
RsaNI	GTAC	3 cut(s)	605, 886, 916
RseI	CAYNNNNRTG	1 cut(s)	483
SalI	GTCGAC	1 cut(s)	269
SaqAI	TTAA	2 cut(s)	525, 534
Sau3AI	GATC	3 cut(s)	220, 255, 468
Sau96I	GGNCC	3 cut(s)	562, 633, 646
SchI	GAGTC	1 cut(s)	225
ScrFI	CCNGG	1 cut(s)	275
SduI	GDGCHC	1 cut(s)	930
SexAI	ACCWGGT	1 cut(s)	273
SfaNI	GCATC	1 cut(s)	563
SfoI	GGCGCC	1 cut(s)	847
Sfr274I	CTCGAG	1 cut(s)	245
SinI	GGWCC	2 cut(s)	562, 646
SlaI	CTCGAG	1 cut(s)	245
SmiMI	CAYNNNNRTG	1 cut(s)	483
SmlI	CTYRAG	4 cut(s)	233, 245, 614, 963
SmoI	CTYRAG	4 cut(s)	233, 245, 614, 963
SpeI	ACTAGT	1 cut(s)	601
SphI	GCATGC	1 cut(s)	496
Sse9I	AATT	2 cut(s)	151, 197
SspDI	GGCGCC	1 cut(s)	845
SspMI	CTAG	3 cut(s)	566, 602, 999
StyD4I	CCNGG	1 cut(s)	273
StyI	CCWWGG	2 cut(s)	558, 988
TaaI	ACNGT	5 cut(s)	35, 77, 205, 574, 1070
TaiI	ACGT	2 cut(s)	594, 933
TaqI	TCGA	2 cut(s)	246, 270
TaqII	GACCGA	1 cut(s)	116
TasI	AATT	2 cut(s)	151, 197
TauI	GCSGC	8 cut(s)	59, 338, 677, 702, 821, 824, 831, 1042
TfiI	GAWTC	1 cut(s)	17
Tru1I	TTAA	2 cut(s)	525, 534
Tru9I	TTAA	2 cut(s)	525, 534
TseI	GCWGC	3 cut(s)	188, 413, 785
TspDTI	ATGAA	3 cut(s)	79, 518, 574
TspGWI	ACGGA	2 cut(s)	194, 810
VpaK11BI	GGWCC	2 cut(s)	562, 646
XapI	RAATTY	1 cut(s)	151
XceI	RCATGY	1 cut(s)	496
XhoI	CTCGAG	1 cut(s)	245
XmiI	GTMKAC	1 cut(s)	270
XmnI	GAANNNNTTC	2 cut(s)	86, 581
XspI	CTAG	3 cut(s)	566, 602, 999

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.