Basic Information

Type: gene

Biological Identity

Species

pyrus_communis

Chromosome

Chr2

Orthogroup ID

OG0009711

Physical Location & Seq

Genomic Coordinates Reverse (-)

22464508 .. 22468993

Gene Structure 4486 bp

Loading structure...

UTR

Exon/CDS

Intron

Transcript / Protein ID

pycom02g24330.2

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1293 bp

ATGACTTGGTTGGGTGCTTCCTCTTCTTCTTCCCCATGGATTCTCAGGAACTCGCTTCTCACAACATCCACAACCTCTTCATCTTCTTCTTCCTCTTCAAAACTCTCGAAATACCGATCATGCCCTCGCCCTCTTCGCCTCTCGAGCCGCGCCCAAGCCGACGTTGGCAGTGACTTCAATTTCGTGCTCCACGATGCTCTCGATTCTTCCGGAACCCTCACCTCCCTCGCCAGAGAGGCCAGGGAGGGGTTCTGCTCACAAATTCGCCATCTGTCTGATATAGAGAGGGAAACCAGCATTACCATCAATAGATGTGTTGATTTGGGGAAAACAGCTCTTTACATTGCAGCAGAAGATGACTCCCTTGTGTCACATTCTTCAGTTCCGCTTCCGGTGGATGCTTTTATTAGTAGGTTTGGTGATCTCTCCATGGACTATTGTTCTCACCACAACTCTTCATTTAGATCCTCGCCTGAGAAATTGTTGGAGAGTTTGGAAAACTATTTGTACGTAAATAAGGGTTTTCGAAGGACGATTGCAAGGTATCACTCTGAATCACGGGCTCTATATCTCCACTCAGTTTTGACGCATCGTTCAGGATCACCTGCAATGCTTTCACTCATATACTCAGAAATTTTGAAAATGCTTCGCCTATGGGGTTTTTTGGATTTCGATGTAGAGATATTCTTTCCTCATGATCTTCATAGTCTTCCCCGAGGTTATCATAAACAGAAAAGCAAGGAATCTGATAATGTCCACATAATGACTTCGCAAGCCCTTTTAGTGGAGATTTTAAGAAATTTGAAGGACGCATTCTGGCCGTTTCAGCATGATCAACCAGGGAATTTGTTCTTGAGGGCAGCACGTGCTGCTAACTTTATCGATAGATCAAACATAAATGAAGACAGTGGCTTTCAGCTTGCATCTGCGAAGGCTGCTCAACATAGACTAGATCGTGGTGTTTGGACTAGTGTACATTTTGGGGATATGAGGCGTGCCCTATCTGCTTGTGAACGTCTTATTCTCCTGGAAGCTGATCCGAAGGAATTAAGAGATTACAGCATTCTTCTCTACCATTGTGGATTTTACGAGGAATCACTTGAATATCTAAAGTTATATCAGGACAAAAAGGGTCGTCCACTACGGAGGCGACCTTCTGATTCGTTAACCGTTTTGGAGGAAGATGCCGCAGAGAAATTGATGATACGCCTTAACCTAATTCTGATGGAGGATGGTTGGAGCAGGCCGTCATATATTAGAAACTTTCTTGGTAACAACTCTGAACCATGGTAG

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

No ontology terms assigned.

KEGG Pathways

Metabolic & Signaling

No pathways identified.

Pfam Domains

Protein Families

Transglut_core2

Protein Analysis

431

Amino Acids

49.03

Weight (kDa)

7.28

Isoelectric Point (pI)

58.39

Instability Index

Protein Domains (Pfam)

No Pfam domains detected for this protein.

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

Style Settings

Font Size (px)

Line Width

Align Labels (Cladogram)

Image

Tree File

Tip: Beautify your tree with professional tools

Download the Full Tree (.nwk) file, then upload it to any of the following tools to customize colors, fonts, annotations, clades, and branch support.

Publication-ready

iTOL Interactive Tree Of Life · Most popular EvolView Flexible annotations MEGA Desktop phylogenetics suite FigTree Desktop tree editor

Orthologous Genes (Group: OG0009711)

Species	Orthologous Gene IDs
fragaria_vesca	FvH4_7g03070
malus_domestica	MD02G1286000.v1.1 MD02G1286500.v1.1 MD02G1286600.v1.1 MD02G1287000.v1.1 MD11G1310600.v1.1 MD14G1215400.v1.1
prunus_persica	Prupe.2G036300_v2.0.a1 Prupe.2G036300_v2.0.a1
pyrus_communis	pycom02g24330
rosa_chinensis	RchiOBHm_Chr1g0324301
rosa_laevigata	RLG00000030205
rosa_multiflora	Rmu_sc0001850.1_g000055 Rmu_sc0004082.1_g000025
rosa_roxburghii	Rroxscaffold_159G00432680 Rroxscaffold_4G00325710
rosa_rugosa	Rorug01G0044900
rosa_samantha	Rh1AG060800 Rh1BG052000 Rh1CG063100 Rh1DG067500
rosa_wichuraiana	Rw1G005180

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AarI	CACCTGC	1 cut(s)	613
Acc36I	ACCTGC	1 cut(s)	613
AccII	CGCG	1 cut(s)	150
AccIII	TCCGGA	1 cut(s)	209
AciI	CCGC	3 cut(s)	148, 386, 1188
AclWI	GGATC	3 cut(s)	459, 607, 1031
AcoI	YGGCCR	1 cut(s)	818
AcsI	RAATTY	4 cut(s)	261, 633, 799, 844
AcuI	CTGAAG	1 cut(s)	363
AcvI	CACGTG	1 cut(s)	866
AfaI	GTAC	2 cut(s)	509, 975
AfiI	CCNNNNNNNGG	2 cut(s)	246, 784
AgsI	TTSAA	5 cut(s)	99, 178, 640, 805, 1103
AhlI	ACTAGT	1 cut(s)	968
AjnI	CCWGG	3 cut(s)	239, 838, 1026
AluBI	AGCT	3 cut(s)	335, 919, 1034
AluI	AGCT	3 cut(s)	335, 919, 1034
Alw21I	GWGCWC	1 cut(s)	189
AlwI	GGATC	3 cut(s)	459, 607, 1031
Ama87I	CYCGRG	2 cut(s)	142, 714
Aor13HI	TCCGGA	1 cut(s)	209
AoxI	GGCC	3 cut(s)	237, 818, 1244
ApeKI	GCWGC	4 cut(s)	347, 860, 869, 935
ApoI	RAATTY	4 cut(s)	261, 633, 799, 844
ArsI	GACNNNNNNTTYG	2 cut(s)	164, 196
Asp700I	GAANNNNTTC	1 cut(s)	848
AspLEI	GCGC	1 cut(s)	152
AsuHPI	GGTGA	4 cut(s)	211, 431, 437, 594
AsuII	TTCGAA	1 cut(s)	526
AvaI	CYCGRG	2 cut(s)	142, 714
BaeGI	GKGCMC	1 cut(s)	1000
BanII	GRGCYC	1 cut(s)	565
BbrPI	CACGTG	1 cut(s)	866
BbsI	GAAGAC	2 cut(s)	701, 909
Bbv12I	GWGCWC	1 cut(s)	189
BbvI	GCAGC	4 cut(s)	359, 856, 872, 922
BccI	CCATC	4 cut(s)	276, 311, 1219, 1226
BceAI	ACGGC	2 cut(s)	805, 1231
BciT130I	CCWGG	3 cut(s)	241, 840, 1028
BclI	TGATCA	1 cut(s)	832
BcuI	ACTAGT	1 cut(s)	968
BfaI	CTAG	2 cut(s)	950, 969
BfuAI	ACCTGC	1 cut(s)	613
BglI	GCCNNNNNGGC	1 cut(s)	236
BisI	GCNGC	6 cut(s)	148, 348, 861, 870, 936, 1188
BlsI	GCNGC	6 cut(s)	149, 349, 862, 871, 937, 1189
Bme1390I	CCNGG	3 cut(s)	241, 840, 1028
BmeT110I	CYCGRG	2 cut(s)	142, 714
BmiI	GGNNCC	1 cut(s)	214
BmrFI	CCNGG	3 cut(s)	241, 840, 1028
BmsI	GCATC	5 cut(s)	184, 388, 598, 932, 1174
BpiI	GAAGAC	2 cut(s)	701, 909
Bpu14I	TTCGAA	1 cut(s)	526
BpuEI	CTTGAG	1 cut(s)	874
Bsa29I	ATCGAT	1 cut(s)	882
BsaAI	YACGTR	2 cut(s)	511, 866
BsaJI	CCNNGG	6 cut(s)	35, 240, 429, 715, 839, 1286
BsaWI	WCCGGW	2 cut(s)	209, 391
Bsc4I	CCNNNNNNNGG	2 cut(s)	246, 784
Bse3DI	GCAATG	2 cut(s)	342, 615
BseAI	TCCGGA	1 cut(s)	209
BseBI	CCWGG	3 cut(s)	241, 840, 1028
BseCI	ATCGAT	1 cut(s)	882
BseDI	CCNNGG	6 cut(s)	35, 240, 429, 715, 839, 1286
BseGI	GGATG	3 cut(s)	65, 403, 1237
BseLI	CCNNNNNNNGG	2 cut(s)	246, 784
BseMI	GCAATG	2 cut(s)	342, 615
BseMII	CTCAG	4 cut(s)	58, 465, 591, 642
BseSI	GKGCMC	1 cut(s)	1000
BseXI	GCAGC	4 cut(s)	359, 856, 872, 922
Bsh1236I	CGCG	1 cut(s)	150
BshFI	GGCC	3 cut(s)	239, 820, 1246
BshVI	ATCGAT	1 cut(s)	882
BsiHKAI	GWGCWC	1 cut(s)	189
BsiHKCI	CYCGRG	2 cut(s)	142, 714
BsiSI	CCGG	2 cut(s)	210, 392
BslI	CCNNNNNNNGG	2 cut(s)	246, 784
BsmI	GAATGC	2 cut(s)	812, 1062
BsnI	GGCC	3 cut(s)	239, 820, 1246
BsoBI	CYCGRG	2 cut(s)	142, 714
Bsp119I	TTCGAA	1 cut(s)	526
Bsp1286I	GDGCHC	3 cut(s)	189, 565, 1000
Bsp13I	TCCGGA	1 cut(s)	209
Bsp1407I	TGTACA	1 cut(s)	973
Bsp143I	GATC	9 cut(s)	116, 421, 464, 599, 697, 832, 887, 952, 1036
Bsp19I	CCATGG	3 cut(s)	35, 429, 1286
BspACI	CCGC	3 cut(s)	148, 386, 1188
BspANI	GGCC	3 cut(s)	239, 820, 1246
BspCNI	CTCAG	4 cut(s)	57, 466, 590, 641
BspDI	ATCGAT	1 cut(s)	882
BspEI	TCCGGA	1 cut(s)	209
BspFNI	CGCG	1 cut(s)	150
BspHI	TCATGA	1 cut(s)	694
BspLI	GGNNCC	1 cut(s)	214
BspMI	ACCTGC	1 cut(s)	613
BspPI	GGATC	3 cut(s)	459, 607, 1031
BspT104I	TTCGAA	1 cut(s)	526
BsrDI	GCAATG	2 cut(s)	342, 615
BsrGI	TGTACA	1 cut(s)	973
BssECI	CCNNGG	6 cut(s)	35, 240, 429, 715, 839, 1286
BssMI	GATC	9 cut(s)	116, 421, 464, 599, 697, 832, 887, 952, 1036
BssT1I	CCWWGG	3 cut(s)	35, 429, 1286
Bst2UI	CCWGG	3 cut(s)	241, 840, 1028
Bst4CI	ACNGT	2 cut(s)	908, 1171
Bst6I	CTCTTC	5 cut(s)	28, 82, 100, 138, 460
BstAPI	GCANNNNNTGC	2 cut(s)	866, 869
BstAUI	TGTACA	1 cut(s)	973
BstBAI	YACGTR	2 cut(s)	511, 866
BstBI	TTCGAA	1 cut(s)	526
BstC8I	GCNNGC	4 cut(s)	774, 921, 996, 1244
BstDEI	CTNAG	4 cut(s)	44, 474, 577, 628
BstDSI	CCRYGG	3 cut(s)	35, 429, 1286
BstF5I	GGATG	3 cut(s)	65, 403, 1237
BstFNI	CGCG	1 cut(s)	150
BstHHI	GCGC	1 cut(s)	152
BstKTI	GATC	9 cut(s)	119, 424, 467, 602, 700, 835, 890, 955, 1039
BstMBI	GATC	9 cut(s)	116, 421, 464, 599, 697, 832, 887, 952, 1036
BstMWI	GCNNNNNNNGC	8 cut(s)	135, 144, 236, 826, 866, 869, 935, 1004
BstNI	CCWGG	3 cut(s)	241, 840, 1028
BstSCI	CCNGG	3 cut(s)	239, 838, 1026
BstSLI	GKGCMC	1 cut(s)	1000
BstSNI	TACGTA	1 cut(s)	511
BstUI	CGCG	1 cut(s)	150
BstV1I	GCAGC	4 cut(s)	359, 856, 872, 922
BstV2I	GAAGAC	2 cut(s)	701, 909
BstX2I	RGATCY	1 cut(s)	464
BstYI	RGATCY	1 cut(s)	464
Bsu15I	ATCGAT	1 cut(s)	882
BsuRI	GGCC	3 cut(s)	239, 820, 1246
BsuTUI	ATCGAT	1 cut(s)	882
BtgI	CCRYGG	3 cut(s)	35, 429, 1286
BtsCI	GGATG	3 cut(s)	65, 403, 1237
BtsI	GCAGTG	1 cut(s)	175
BtsIMutI	CAGTG	2 cut(s)	175, 913
BveI	ACCTGC	1 cut(s)	613
Cac8I	GCNNGC	4 cut(s)	774, 921, 996, 1244
CciI	TCATGA	1 cut(s)	694
CfoI	GCGC	1 cut(s)	152
ClaI	ATCGAT	1 cut(s)	882
CseI	GACGC	2 cut(s)	595, 818
Csp6I	GTAC	2 cut(s)	508, 974
CviAII	CATG	6 cut(s)	36, 120, 430, 695, 830, 1287
CviQI	GTAC	2 cut(s)	508, 974
DdeI	CTNAG	4 cut(s)	44, 474, 577, 628
DpnI	GATC	9 cut(s)	118, 423, 466, 601, 699, 834, 889, 954, 1038
DpnII	GATC	9 cut(s)	116, 421, 464, 599, 697, 832, 887, 952, 1036
EaeI	YGGCCR	1 cut(s)	818
Eam1104I	CTCTTC	5 cut(s)	28, 82, 100, 138, 460
EarI	CTCTTC	5 cut(s)	28, 82, 100, 138, 460
Eco105I	TACGTA	1 cut(s)	511
Eco130I	CCWWGG	3 cut(s)	35, 429, 1286
Eco24I	GRGCYC	1 cut(s)	565
Eco57I	CTGAAG	1 cut(s)	363
Eco72I	CACGTG	1 cut(s)	866
Eco88I	CYCGRG	2 cut(s)	142, 714
EcoRII	CCWGG	3 cut(s)	239, 838, 1026
EcoT14I	CCWWGG	3 cut(s)	35, 429, 1286
EcoT38I	GRGCYC	1 cut(s)	565
ErhI	CCWWGG	3 cut(s)	35, 429, 1286
FaeI	CATG	6 cut(s)	39, 123, 433, 698, 833, 1290
FatI	CATG	6 cut(s)	35, 119, 429, 694, 829, 1286
FbaI	TGATCA	1 cut(s)	832
Fnu4HI	GCNGC	6 cut(s)	148, 348, 861, 870, 936, 1188
FokI	GGATG	3 cut(s)	52, 410, 1244
FriOI	GRGCYC	1 cut(s)	565
Fsp4HI	GCNGC	6 cut(s)	148, 348, 861, 870, 936, 1188
FspBI	CTAG	2 cut(s)	950, 969
GlaI	GCGC	1 cut(s)	151
GluI	GCNGC	6 cut(s)	148, 348, 861, 870, 936, 1188
HaeIII	GGCC	3 cut(s)	239, 820, 1246
HapII	CCGG	2 cut(s)	210, 392
HgaI	GACGC	2 cut(s)	595, 818
HhaI	GCGC	1 cut(s)	152
Hin1II	CATG	6 cut(s)	39, 123, 433, 698, 833, 1290
Hin6I	GCGC	1 cut(s)	150
HinP1I	GCGC	1 cut(s)	150
HincII	GTYRAC	1 cut(s)	1167
HindII	GTYRAC	1 cut(s)	1167
HinfI	GANTC	7 cut(s)	40, 203, 359, 554, 743, 1094, 1160
HpaI	GTTAAC	1 cut(s)	1167
HpaII	CCGG	2 cut(s)	210, 392
HphI	GGTGA	4 cut(s)	211, 431, 437, 594
Hpy166II	GTNNAC	5 cut(s)	757, 974, 1013, 1139, 1167
Hpy188I	TCNGA	8 cut(s)	277, 553, 631, 748, 1041, 1159, 1224, 1282
Hpy188III	TCNNGA	9 cut(s)	46, 106, 142, 200, 210, 597, 695, 853, 1121
Hpy8I	GTNNAC	5 cut(s)	757, 974, 1013, 1139, 1167
Hpy99I	CGWCG	1 cut(s)	164
HpyAV	CCTTC	5 cut(s)	522, 799, 925, 1036, 1164
HpyCH4III	ACNGT	2 cut(s)	908, 1171
HpyCH4IV	ACGT	4 cut(s)	162, 510, 865, 1015
HpyCH4V	TGCA	4 cut(s)	347, 539, 608, 923
HpyF10VI	GCNNNNNNNGC	8 cut(s)	135, 144, 236, 826, 866, 869, 935, 1004
HpyF3I	CTNAG	4 cut(s)	44, 474, 577, 628
HpySE526I	ACGT	4 cut(s)	162, 510, 865, 1015
Hsp92II	CATG	6 cut(s)	39, 123, 433, 698, 833, 1290
HspAI	GCGC	1 cut(s)	150
Kpn2I	TCCGGA	1 cut(s)	209
Ksp22I	TGATCA	1 cut(s)	832
KspAI	GTTAAC	1 cut(s)	1167
Kzo9I	GATC	9 cut(s)	116, 421, 464, 599, 697, 832, 887, 952, 1036
LmnI	GCTCC	2 cut(s)	192, 1239
Lsp1109I	GCAGC	4 cut(s)	359, 856, 872, 922
LweI	GCATC	5 cut(s)	184, 388, 598, 932, 1174
MaeI	CTAG	2 cut(s)	950, 969
MaeII	ACGT	4 cut(s)	162, 510, 865, 1015
MaeIII	GTNAC	3 cut(s)	170, 369, 1271
MalI	GATC	9 cut(s)	118, 423, 466, 601, 699, 834, 889, 954, 1038
MboI	GATC	9 cut(s)	116, 421, 464, 599, 697, 832, 887, 952, 1036
MflI	RGATCY	1 cut(s)	464
MhlI	GDGCHC	3 cut(s)	189, 565, 1000
MluCI	AATT	9 cut(s)	178, 261, 479, 633, 799, 844, 1046, 1196, 1218
MlyI	GAGTC	1 cut(s)	353
MmeI	TCCRAC	2 cut(s)	465, 1217
MroI	TCCGGA	1 cut(s)	209
MroXI	GAANNNNTTC	1 cut(s)	848
MseI	TTAA	4 cut(s)	794, 1049, 1166, 1212
MspI	CCGG	2 cut(s)	210, 392
MspR9I	CCNGG	3 cut(s)	241, 840, 1028
Mva1269I	GAATGC	2 cut(s)	812, 1062
MvaI	CCWGG	3 cut(s)	241, 840, 1028
MvnI	CGCG	1 cut(s)	150
MwoI	GCNNNNNNNGC	8 cut(s)	135, 144, 236, 826, 866, 869, 935, 1004
NcoI	CCATGG	3 cut(s)	35, 429, 1286
NdeII	GATC	9 cut(s)	116, 421, 464, 599, 697, 832, 887, 952, 1036
NlaIII	CATG	6 cut(s)	39, 123, 433, 698, 833, 1290
NlaIV	GGNNCC	1 cut(s)	214
NmuCI	GTSAC	2 cut(s)	170, 369
NspV	TTCGAA	1 cut(s)	526
PaeR7I	CTCGAG	1 cut(s)	142
PagI	TCATGA	1 cut(s)	694
PaqCI	CACCTGC	1 cut(s)	613
PcsI	WCGNNNNNNNCGW	2 cut(s)	189, 198
PctI	GAATGC	2 cut(s)	812, 1062
PdmI	GAANNNNTTC	1 cut(s)	848
PfeI	GAWTC	6 cut(s)	40, 203, 554, 743, 1094, 1160
PfoI	TCCNGGA	1 cut(s)	1026
PkrI	GCNGC	6 cut(s)	149, 349, 862, 871, 937, 1189
PleI	GAGTC	1 cut(s)	353
PmaCI	CACGTG	1 cut(s)	866
PmlI	CACGTG	1 cut(s)	866
PpsI	GAGTC	1 cut(s)	353
Ppu21I	YACGTR	2 cut(s)	511, 866
Psp6I	CCWGG	3 cut(s)	239, 838, 1026
PspCI	CACGTG	1 cut(s)	866
PspGI	CCWGG	3 cut(s)	239, 838, 1026
PspN4I	GGNNCC	1 cut(s)	214
PsuI	RGATCY	1 cut(s)	464
RsaI	GTAC	2 cut(s)	509, 975
RsaNI	GTAC	2 cut(s)	508, 974
SaqAI	TTAA	4 cut(s)	794, 1049, 1166, 1212
SatI	GCNGC	6 cut(s)	148, 348, 861, 870, 936, 1188
Sau3AI	GATC	9 cut(s)	116, 421, 464, 599, 697, 832, 887, 952, 1036
SchI	GAGTC	1 cut(s)	353
ScrFI	CCNGG	3 cut(s)	241, 840, 1028
SduI	GDGCHC	3 cut(s)	189, 565, 1000
SfaNI	GCATC	5 cut(s)	184, 388, 598, 932, 1174
Sfr274I	CTCGAG	1 cut(s)	142
SfuI	TTCGAA	1 cut(s)	526
SlaI	CTCGAG	1 cut(s)	142
SmlI	CTYRAG	2 cut(s)	142, 853
SmoI	CTYRAG	2 cut(s)	142, 853
SnaBI	TACGTA	1 cut(s)	511
SpeI	ACTAGT	1 cut(s)	968
Sse9I	AATT	9 cut(s)	178, 261, 479, 633, 799, 844, 1046, 1196, 1218
SsiI	CCGC	3 cut(s)	148, 386, 1188
SspMI	CTAG	2 cut(s)	950, 969
StyD4I	CCNGG	3 cut(s)	239, 838, 1026
StyI	CCWWGG	3 cut(s)	35, 429, 1286
TaaI	ACNGT	2 cut(s)	908, 1171
TaiI	ACGT	4 cut(s)	165, 513, 868, 1018
TaqI	TCGA	6 cut(s)	107, 143, 201, 526, 672, 882
TasI	AATT	9 cut(s)	178, 261, 479, 633, 799, 844, 1046, 1196, 1218
TatI	WGTACW	1 cut(s)	973
TauI	GCSGC	2 cut(s)	150, 1190
TfiI	GAWTC	6 cut(s)	40, 203, 554, 743, 1094, 1160
Tru1I	TTAA	4 cut(s)	794, 1049, 1166, 1212
Tru9I	TTAA	4 cut(s)	794, 1049, 1166, 1212
TscAI	CASTG	2 cut(s)	175, 913
TseFI	GTSAC	2 cut(s)	170, 369
TseI	GCWGC	4 cut(s)	347, 860, 869, 935
Tsp45I	GTSAC	2 cut(s)	170, 369
TspDTI	ATGAA	4 cut(s)	69, 447, 692, 915
TspGWI	ACGGA	1 cut(s)	1159
TspRI	CASTG	2 cut(s)	175, 913
XapI	RAATTY	4 cut(s)	261, 633, 799, 844
XcmI	CCANNNNNNNNNTGG	1 cut(s)	161
XhoI	CTCGAG	1 cut(s)	142
XmnI	GAANNNNTTC	1 cut(s)	848
XspI	CTAG	2 cut(s)	950, 969

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.