AT5G39400

C2 domain of PTEN tumour-suppressor protein

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
arabidopsis_thaliana
5
OG0001990
Physical Location & Seq
Forward (+)
15766037 .. 15768354
2318 bp
Loading structure...
UTR
Exon/CDS
Intron
AT5G39400.1

Sequence Viewer

Length: 1239 bp
ATGGGTCTCAAGCTCTCACGAGGGCCTGTAAAAGAAAAATCACCTTTGGAATTCACAAGGGTTCACATTCTGACTTACTTCACCACAAATTCTTACCTACGTAACTTGGTGTCCAAGAAACGAAGACGGTTAATCATCGGTGGATATGATCTCGACATGTCTTACATCTCCGACAAATTATTGGCAATGTCTTTTCCAGCTGAACGAATGAGAGCAGTCTATAGAAACCCTCTTTGGCAAGTCAAGTCCGTGCTCGATATGCGACATCCTGATCATTACAAGGTCTATAATCTATGTATAGAGGAATCTTATGATCCAGACAACTTTTATGGCCGCGTGGAGCGATTTCCGTTTGATGACAATCATGTTCCATCCCTCAAAATGATCCAACTTTTCTGTGAAAGTGTTCATTCTTGGCTCTCATTAGATCCCAAGAACATCGCGGTTGTTCATTGCATGGCAGGAAAAGGTAGAACAGGGCTAATGGTATCGGCGTACCTTGTTTACGGTGGCATGTCAGCTGAAGAAGCTCTTGAGATGTATGCAAGCAGAAGAACAACAAACAATAATGGAGTCTCAATACCAAGCCAACGTCGTTATGTGAAGTACTGGTCAGATTTACTTTCGTTCAGTAAAAAAGGACCTCCCGAGGTTAAATTACCGCAAGAACATAGCAGAGAGTTGTTGCGAATTAGACTTTATGATACAGCTAACGTTGATTCCGTCTTCTTTGTGGTTTCAGAACTTCAGGAGGTTCCAAATGAGATGTATCGACCGTCTGTAGAACTTGCAAGAGGTTGTTGTAGACAATTCAAGAAAGGGTATTGTAGAAGTTCGAGTCCACGGTATTATATATCTCATGTGAACTGTGATTCAGAAGAAGATGAGGAAGTAACAGACGGAGAAGAGCCACATCTTGTTGTTCAGATGGATACAGAGAGTTCCATTATCGACGAAAAAACTTGTCTTGATTTCTACTTTGACAAACCTGTGAGAGTTAGTGGTGACATACGCATCACATTCTACCAGAAAATGATTGGAAGCCGCCTTTTTTATACTTGCTTCAACACAGCTTTTATAACCAATGGCTTACTTCAGTTTTCCATAGGAGAGCTAGATAAAGTTGGTGGTAACGGAAGATCGATATCTGGTCCTGATTTTAGCTTGGAGTTACTCTTTGGCCCAGCTTGTTCGAAATTCGGAAAGTTTCTTTCCCGCGATGACCTTTCTCTCTCTTGA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
GO:0000278 GO:0000281 GO:0000910 GO:0001931 GO:0001932 GO:0001933 GO:0003674 GO:0003824 GO:0004721 GO:0004725 GO:0005575 GO:0005622 GO:0005623 GO:0005737 GO:0005829 GO:0005886 GO:0005938 GO:0006464 GO:0006469 GO:0006470 GO:0006629 GO:0006644 GO:0006650 GO:0006793 GO:0006796 GO:0006807 GO:0006928 GO:0006935 GO:0006950 GO:0006996 GO:0007010 GO:0007015 GO:0007049 GO:0007154 GO:0007163 GO:0007165 GO:0007186 GO:0007187 GO:0007188 GO:0007275 GO:0008104 GO:0008150 GO:0008152 GO:0008154 GO:0009267 GO:0009555 GO:0009605 GO:0009892 GO:0009987 GO:0009991 GO:0010563 GO:0010605 GO:0014065 GO:0016020 GO:0016043 GO:0016311 GO:0016787 GO:0016788 GO:0016791 GO:0019220 GO:0019222 GO:0019538 GO:0019637 GO:0022402 GO:0022603 GO:0022604 GO:0022607 GO:0023052 GO:0030010 GO:0030029 GO:0030030 GO:0030031 GO:0030036 GO:0030041 GO:0030258 GO:0030587 GO:0031152 GO:0031254 GO:0031257 GO:0031268 GO:0031269 GO:0031272 GO:0031279 GO:0031323 GO:0031324 GO:0031344 GO:0031399 GO:0031400 GO:0031667 GO:0031668 GO:0031669 GO:0032153 GO:0032155 GO:0032268 GO:0032269 GO:0032501 GO:0032502 GO:0032796 GO:0032879 GO:0033036 GO:0033554 GO:0033673 GO:0034461 GO:0034485 GO:0034593 GO:0034594 GO:0034595 GO:0034613 GO:0034622 GO:0035335 GO:0035556 GO:0036051 GO:0036052 GO:0036211 GO:0040011 GO:0042221 GO:0042325 GO:0042326 GO:0042330 GO:0042578 GO:0042594 GO:0042995 GO:0043086 GO:0043170 GO:0043327 GO:0043412 GO:0043549 GO:0043933 GO:0044085 GO:0044087 GO:0044092 GO:0044237 GO:0044238 GO:0044255 GO:0044260 GO:0044267 GO:0044424 GO:0044425 GO:0044444 GO:0044448 GO:0044459 GO:0044464 GO:0044764 GO:0045761 GO:0045859 GO:0045936 GO:0046486 GO:0046488 GO:0046839 GO:0046856 GO:0048015 GO:0048017 GO:0048229 GO:0048518 GO:0048519 GO:0048522 GO:0048523 GO:0048856 GO:0048870 GO:0050789 GO:0050790 GO:0050793 GO:0050794 GO:0050896 GO:0050919 GO:0051128 GO:0051171 GO:0051172 GO:0051174 GO:0051179 GO:0051246 GO:0051248 GO:0051258 GO:0051270 GO:0051272 GO:0051285 GO:0051286 GO:0051301 GO:0051338 GO:0051339 GO:0051348 GO:0051641 GO:0051674 GO:0051703 GO:0051704 GO:0051716 GO:0051800 GO:0052866 GO:0060255 GO:0060491 GO:0061640 GO:0065003 GO:0065007 GO:0065009 GO:0070727 GO:0071496 GO:0071704 GO:0071840 GO:0071900 GO:0071901 GO:0071944 GO:0080090 GO:0090702 GO:0097435 GO:0098630 GO:0098743 GO:0099120 GO:0099568 GO:0099738 GO:0106017 GO:0120025 GO:0120031 GO:0120032 GO:0120035 GO:0120036 GO:0140096 GO:1901564 GO:1903047 GO:1990753
KEGG Pathways
Metabolic & Signaling
ko00562 ko01521 ko04068 ko04070 ko04071 ko04115 ko04140 ko04150 ko04151 ko04212 ko04218 ko04510 ko04931 ko05161 ko05165 ko05200 ko05206 ko05213 ko05214 ko05215 ko05218 ko05222 ko05224 ko05225 ko05230 map00562 map01521 map04068 map04070 map04071 map04115 map04140 map04150 map04151 map04212 map04218 map04510 map04931 map05161 map05165 map05200 map05206 map05213 map05214 map05215 map05218 map05222 map05224 map05225 map05230
Pfam Domains
Protein Families
DSPc PTEN_C2 Y_phosphatase3

Protein Analysis

412

Amino Acids

47.35

Weight (kDa)

7.54

Isoelectric Point (pI)

53.64

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
PTP-NADK PF22741 81 - 186 3.4e-09 DSP-PTPase phosphatase fused to NAD+ Kinase
Tc-R-P PF22785 113 - 171 8.3e-10 Polymorphic toxin system, DSP-PTPase phosphatase
PTP-SAK PF22784 115 - 180 5e-09 Swiss Army Knife protein, DSP-PTPase phosphatase domain
DSPc PF00782 148 - 187 6.1e-06 Dual specificity phosphatase, catalytic domain
PTEN_C2 PF10409 318 - 394 6.9e-11 C2 domain of PTEN tumour-suppressor protein
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AanI TTATAA 1 cut(s) 1079
AccI GTMKAC 1 cut(s) 805
AccII CGCG 3 cut(s) 336, 443, 1218
AciI CCGC 5 cut(s) 334, 443, 662, 1045, 1216
AclI AACGTT 1 cut(s) 714
AclWI GGATC 3 cut(s) 308, 379, 422
AcoI YGGCCR 1 cut(s) 331
AcsI RAATTY 3 cut(s) 50, 88, 1196
AcuI CTGAAG 3 cut(s) 543, 731, 1079
AfaI GTAC 2 cut(s) 497, 608
AflIII ACRYGT 1 cut(s) 156
AgsI TTSAA 2 cut(s) 814, 1066
AjuI GAANNNNNNNTTGG 2 cut(s) 217, 249
AluBI AGCT 9 cut(s) 13, 200, 521, 530, 710, 1073, 1114, 1164, 1187
AluI AGCT 9 cut(s) 13, 200, 521, 530, 710, 1073, 1114, 1164, 1187
Alw21I GWGCWC 1 cut(s) 255
Alw26I GTCTC 2 cut(s) 11, 580
AlwI GGATC 3 cut(s) 308, 379, 422
Ama87I CYCGRG 1 cut(s) 647
AoxI GGCC 3 cut(s) 23, 331, 1180
ApoI RAATTY 3 cut(s) 50, 88, 1196
Asp700I GAANNNNTTC 1 cut(s) 405
AspS9I GGNCC 4 cut(s) 23, 641, 1151, 1181
AsuHPI GGTGA 3 cut(s) 33, 73, 1016
AsuII TTCGAA 1 cut(s) 1193
AvaI CYCGRG 1 cut(s) 647
AvaII GGWCC 2 cut(s) 641, 1151
BauI CACGAG 1 cut(s) 18
BbsI GAAGAC 2 cut(s) 130, 718
Bbv12I GWGCWC 1 cut(s) 255
BccI CCATC 2 cut(s) 379, 922
BciVI GTATCC 1 cut(s) 925
BclI TGATCA 1 cut(s) 271
BcoDI GTCTC 2 cut(s) 11, 580
BfaI CTAG 1 cut(s) 1115
BfmI CTRYAG 2 cut(s) 220, 780
BfuI GTATCC 1 cut(s) 925
BisI GCNGC 2 cut(s) 334, 1045
BlsI GCNGC 2 cut(s) 335, 1046
BmcAI AGTACT 1 cut(s) 608
Bme18I GGWCC 2 cut(s) 641, 1151
BmeT110I CYCGRG 1 cut(s) 647
BmgT120I GGNCC 4 cut(s) 23, 641, 1151, 1181
BmiI GGNNCC 1 cut(s) 756
BmsI GCATC 1 cut(s) 1023
BpiI GAAGAC 2 cut(s) 130, 718
Bpu14I TTCGAA 1 cut(s) 1193
BpuEI CTTGAG 1 cut(s) 554
Bsa29I ATCGAT 1 cut(s) 1142
BsaAI YACGTR 1 cut(s) 101
BsaBI GATNNNNATC 2 cut(s) 360, 1144
BsaI GGTCTC 1 cut(s) 11
BsaJI CCNNGG 2 cut(s) 648, 842
Bse1I ACTGG 1 cut(s) 614
Bse3DI GCAATG 2 cut(s) 192, 451
Bse8I GATNNNNATC 2 cut(s) 360, 1144
BseCI ATCGAT 1 cut(s) 1142
BseDI CCNNGG 2 cut(s) 648, 842
BseGI GGATG 2 cut(s) 265, 371
BseJI GATNNNNATC 2 cut(s) 360, 1144
BseMI GCAATG 2 cut(s) 192, 451
BseNI ACTGG 1 cut(s) 614
BseYI CCCAGC 1 cut(s) 1183
Bsh1236I CGCG 3 cut(s) 336, 443, 1218
Bsh1285I CGRYCG 1 cut(s) 776
BshFI GGCC 3 cut(s) 25, 333, 1182
BshVI ATCGAT 1 cut(s) 1142
BsiEI CGRYCG 1 cut(s) 776
BsiHKAI GWGCWC 1 cut(s) 255
BsiHKCI CYCGRG 1 cut(s) 647
BsmAI GTCTC 2 cut(s) 11, 580
BsnI GGCC 3 cut(s) 25, 333, 1182
Bso31I GGTCTC 1 cut(s) 11
BsoBI CYCGRG 1 cut(s) 647
Bsp119I TTCGAA 1 cut(s) 1193
Bsp1286I GDGCHC 1 cut(s) 255
Bsp143I GATC 6 cut(s) 148, 271, 313, 384, 427, 1139
BspACI CCGC 5 cut(s) 334, 443, 662, 1045, 1216
BspANI GGCC 3 cut(s) 25, 333, 1182
BspDI ATCGAT 1 cut(s) 1142
BspFNI CGCG 3 cut(s) 336, 443, 1218
BspLI GGNNCC 1 cut(s) 756
BspPI GGATC 3 cut(s) 308, 379, 422
BspQI GCTCTTC 1 cut(s) 900
BspT104I TTCGAA 1 cut(s) 1193
BspTNI GGTCTC 1 cut(s) 11
BsrDI GCAATG 2 cut(s) 192, 451
BsrI ACTGG 1 cut(s) 614
BssECI CCNNGG 2 cut(s) 648, 842
BssMI GATC 6 cut(s) 148, 271, 313, 384, 427, 1139
BssSI CACGAG 1 cut(s) 18
Bst2BI CACGAG 1 cut(s) 18
Bst4CI ACNGT 5 cut(s) 129, 509, 777, 846, 869
Bst6I CTCTTC 1 cut(s) 900
BstBAI YACGTR 1 cut(s) 101
BstBI TTCGAA 1 cut(s) 1193
BstC8I GCNNGC 1 cut(s) 547
BstDSI CCRYGG 1 cut(s) 842
BstF5I GGATG 2 cut(s) 265, 371
BstFNI CGCG 3 cut(s) 336, 443, 1218
BstKTI GATC 6 cut(s) 151, 274, 316, 387, 430, 1142
BstMAI GTCTC 2 cut(s) 11, 580
BstMBI GATC 6 cut(s) 148, 271, 313, 384, 427, 1139
BstMCI CGRYCG 1 cut(s) 776
BstMWI GCNNNNNNNGC 2 cut(s) 259, 527
BstNSI RCATGY 2 cut(s) 160, 517
BstSFI CTRYAG 2 cut(s) 220, 780
BstSNI TACGTA 1 cut(s) 101
BstUI CGCG 3 cut(s) 336, 443, 1218
BstV2I GAAGAC 2 cut(s) 130, 718
BstX2I RGATCY 1 cut(s) 427
BstYI RGATCY 1 cut(s) 427
Bsu15I ATCGAT 1 cut(s) 1142
BsuI GTATCC 1 cut(s) 925
BsuRI GGCC 3 cut(s) 25, 333, 1182
BsuTUI ATCGAT 1 cut(s) 1142
BtgI CCRYGG 1 cut(s) 842
BtgZI GCGATG 2 cut(s) 424, 1233
BtsCI GGATG 2 cut(s) 265, 371
Cac8I GCNNGC 1 cut(s) 547
Cfr13I GGNCC 4 cut(s) 23, 641, 1151, 1181
ClaI ATCGAT 1 cut(s) 1142
Csp6I GTAC 2 cut(s) 496, 607
CviAII CATG 5 cut(s) 157, 365, 457, 514, 860
CviQI GTAC 2 cut(s) 496, 607
DpnI GATC 6 cut(s) 150, 273, 315, 386, 429, 1141
DpnII GATC 6 cut(s) 148, 271, 313, 384, 427, 1139
EaeI YGGCCR 1 cut(s) 331
Eam1104I CTCTTC 1 cut(s) 900
EarI CTCTTC 1 cut(s) 900
Eco105I TACGTA 1 cut(s) 101
Eco31I GGTCTC 1 cut(s) 11
Eco32I GATATC 1 cut(s) 1146
Eco47I GGWCC 2 cut(s) 641, 1151
Eco57I CTGAAG 3 cut(s) 543, 731, 1079
Eco88I CYCGRG 1 cut(s) 647
EcoO109I RGGNCCY 2 cut(s) 23, 641
EcoRI GAATTC 1 cut(s) 50
EcoRV GATATC 1 cut(s) 1146
FaeI CATG 5 cut(s) 160, 368, 460, 517, 863
FalI AAGNNNNNCTT 2 cut(s) 516, 548
FatI CATG 5 cut(s) 156, 364, 456, 513, 859
FauI CCCGC 1 cut(s) 1223
FbaI TGATCA 1 cut(s) 271
FblI GTMKAC 1 cut(s) 805
Fnu4HI GCNGC 2 cut(s) 334, 1045
FokI GGATG 2 cut(s) 252, 358
Fsp4HI GCNGC 2 cut(s) 334, 1045
FspBI CTAG 1 cut(s) 1115
GluI GCNGC 2 cut(s) 334, 1045
GsaI CCCAGC 1 cut(s) 1187
HaeIII GGCC 3 cut(s) 25, 333, 1182
Hin1II CATG 5 cut(s) 160, 368, 460, 517, 863
HinfI GANTC 5 cut(s) 305, 573, 719, 838, 872
HphI GGTGA 3 cut(s) 33, 73, 1016
Hpy166II GTNNAC 5 cut(s) 64, 505, 806, 842, 865
Hpy188I TCNGA 7 cut(s) 72, 172, 616, 742, 877, 927, 1202
Hpy8I GTNNAC 5 cut(s) 64, 505, 806, 842, 865
Hpy99I CGWCG 2 cut(s) 597, 956
HpyCH4III ACNGT 5 cut(s) 129, 509, 777, 846, 869
HpyCH4IV ACGT 3 cut(s) 100, 592, 714
HpyCH4V TGCA 3 cut(s) 456, 545, 791
HpyF10VI GCNNNNNNNGC 2 cut(s) 259, 527
HpySE526I ACGT 3 cut(s) 100, 592, 714
Hsp92II CATG 5 cut(s) 160, 368, 460, 517, 863
Ksp22I TGATCA 1 cut(s) 271
Kzo9I GATC 6 cut(s) 148, 271, 313, 384, 427, 1139
LguI GCTCTTC 1 cut(s) 900
LmnI GCTCC 1 cut(s) 340
LweI GCATC 1 cut(s) 1023
MaeI CTAG 1 cut(s) 1115
MaeII ACGT 3 cut(s) 100, 592, 714
MaeIII GTNAC 5 cut(s) 101, 892, 1004, 1130, 1170
MalI GATC 6 cut(s) 150, 273, 315, 386, 429, 1141
MboI GATC 6 cut(s) 148, 271, 313, 384, 427, 1139
MboII GAAGA 8 cut(s) 135, 536, 564, 718, 890, 893, 917, 1149
MflI RGATCY 1 cut(s) 427
MhlI GDGCHC 1 cut(s) 255
MluCI AATT 7 cut(s) 50, 88, 176, 656, 690, 809, 1196
MlyI GAGTC 2 cut(s) 582, 847
MmeI TCCRAC 2 cut(s) 195, 412
MnlI CCTC 9 cut(s) 14, 240, 295, 386, 643, 654, 745, 788, 880
MroXI GAANNNNTTC 1 cut(s) 405
MseI TTAA 2 cut(s) 131, 654
MspA1I CMGCKG 2 cut(s) 200, 521
MvnI CGCG 3 cut(s) 336, 443, 1218
MwoI GCNNNNNNNGC 2 cut(s) 259, 527
NdeII GATC 6 cut(s) 148, 271, 313, 384, 427, 1139
NlaIII CATG 5 cut(s) 160, 368, 460, 517, 863
NlaIV GGNNCC 1 cut(s) 756
NmuCI GTSAC 1 cut(s) 1004
NspI RCATGY 2 cut(s) 160, 517
NspV TTCGAA 1 cut(s) 1193
PciI ACATGT 1 cut(s) 156
PciSI GCTCTTC 1 cut(s) 900
PcsI WCGNNNNNNNCGW 1 cut(s) 720
PdmI GAANNNNTTC 1 cut(s) 405
PfeI GAWTC 3 cut(s) 305, 719, 872
PkrI GCNGC 2 cut(s) 335, 1046
PleI GAGTC 2 cut(s) 581, 846
PpsI GAGTC 2 cut(s) 581, 846
Ppu21I YACGTR 1 cut(s) 101
PpuMI RGGWCCY 1 cut(s) 641
PscI ACATGT 1 cut(s) 156
PsiI TTATAA 1 cut(s) 1079
Psp1406I AACGTT 1 cut(s) 714
Psp5II RGGWCCY 1 cut(s) 641
PspFI CCCAGC 1 cut(s) 1183
PspN4I GGNNCC 1 cut(s) 756
PspPI GGNCC 4 cut(s) 23, 641, 1151, 1181
PspPPI RGGWCCY 1 cut(s) 641
PsuI RGATCY 1 cut(s) 427
PvuII CAGCTG 2 cut(s) 200, 521
RsaI GTAC 2 cut(s) 497, 608
RsaNI GTAC 2 cut(s) 496, 607
SapI GCTCTTC 1 cut(s) 900
SaqAI TTAA 2 cut(s) 131, 654
SatI GCNGC 2 cut(s) 334, 1045
Sau3AI GATC 6 cut(s) 148, 271, 313, 384, 427, 1139
Sau96I GGNCC 4 cut(s) 23, 641, 1151, 1181
ScaI AGTACT 1 cut(s) 608
SchI GAGTC 2 cut(s) 582, 847
SduI GDGCHC 1 cut(s) 255
SfaNI GCATC 1 cut(s) 1023
SfcI CTRYAG 2 cut(s) 220, 780
SfuI TTCGAA 1 cut(s) 1193
SinI GGWCC 2 cut(s) 641, 1151
SmlI CTYRAG 2 cut(s) 8, 533
SmoI CTYRAG 2 cut(s) 8, 533
SnaBI TACGTA 1 cut(s) 101
Sse9I AATT 7 cut(s) 50, 88, 176, 656, 690, 809, 1196
SsiI CCGC 5 cut(s) 334, 443, 662, 1045, 1216
SspMI CTAG 1 cut(s) 1115
TaaI ACNGT 5 cut(s) 129, 509, 777, 846, 869
TaiI ACGT 3 cut(s) 103, 595, 717
TaqI TCGA 7 cut(s) 153, 255, 772, 836, 951, 1142, 1193
TasI AATT 7 cut(s) 50, 88, 176, 656, 690, 809, 1196
TatI WGTACW 1 cut(s) 606
TauI GCSGC 2 cut(s) 336, 1047
TfiI GAWTC 3 cut(s) 305, 719, 872
Tru1I TTAA 2 cut(s) 131, 654
Tru9I TTAA 2 cut(s) 131, 654
TseFI GTSAC 1 cut(s) 1004
Tsp45I GTSAC 1 cut(s) 1004
TspDTI ATGAA 2 cut(s) 398, 440
TspGWI ACGGA 5 cut(s) 238, 339, 712, 915, 1149
VpaK11BI GGWCC 2 cut(s) 641, 1151
XapI RAATTY 3 cut(s) 50, 88, 1196
XceI RCATGY 2 cut(s) 160, 517
XcmI CCANNNNNNNNNTGG 1 cut(s) 1034
XmiI GTMKAC 1 cut(s) 805
XmnI GAANNNNTTC 1 cut(s) 405
XspI CTAG 1 cut(s) 1115
ZrmI AGTACT 1 cut(s) 608
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.