Basic Information

Type: gene

Biological Identity

Species

rosa_roxburghii

Chromosome

GWHEROQ00000004

Orthogroup ID

OG0004452

Physical Location & Seq

Genomic Coordinates Forward (+)

2776555 .. 2780478

Gene Structure 3924 bp

Loading structure...

UTR

Exon/CDS

Intron

Transcript / Protein ID

Rroxscaffold_4G00280130.1

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1179 bp

ATGTCAAAACAATTGGAGAGATACCAAAAACTTGCGCTGAAAGAATCTTTAGGATCAATTCACAGATACCCTTTAGTCTGCAAAGAGCTCAGCTTAATTCTCAGAGGCGCTTACAGAAAAGTGCCCAAGAATCTCCAGTCTCTTATCTTCCAAGATACCCTCACCGCCTTTCGTCTCCTTCCTGAAATGAAGACGCGCAGTGCTGTCTCAGCAGCTCACCTCCTCCTCCAGAGCGTTGAGGCCACTTTGCCGAAGCAAAAGAAGAACTTGGCTGTTACAGAATATAAGAATGCAATGATTGCTCACAAGAGGCGCGCTAAAGCTCGCCAAGAAGAGAATGTTGCCCATCTGCCACAAGATGTTCTTGTACATGTATTCAGTTTCCTGGATTTTCAATCTTTAGTCTCTGTTGGGCAAGTCTGCTGGCCATGGAATTTTGCAGCAAGTGATAACCGGCTGTGGCAGAGGCAATACGCTACGTTCTTTAGGGACTCTTACAATGACTTGAATATCAAGGAACAGCATACCAGTAGACAGGTTGAAGATGATAGTTATACGCTGTTTTGGAGAAAAGCCTTCAAAAGAGCATATAAAGGGAATAATTCATCAAAGAAATTAAAATCCAGTAGGGGATACTGTAGATACTGCAAGACAATTGTTTGGCTCGATAACATGAAATGTTTCAATAACCATATTGGACTAAATCCTGAAATTCAGAAAATTGACCCTGTATCACCTAGTCAGGTGGTTGACTATCTGTTGGAAGATTCTATATCAGTCAAATCTTCTTCAGAGAGTGATAGCGACAGTGATTCAGAAGCAGGGTCCTTTTCTAGGTATCCCAGTATCAATGCAGATGATGCTATCCTTAATTGGCCAAGGATTCATCAAAATGAAGAGGAACTTGGGGCACAAAGAGGAATCAAGAATGTACCAATCAAGATCATCATTCCAGAGATGGTGTACTGTAATGGGAACAAAGCTACTTCACCTACGGGCTGCAAACATCTCACCGATATGAATCCAATGTCTTTTAAACCATCTCCCTGCATCTGGTTTTACTTTGATCCACCACCTCAAAGCAAATCAAATCATACACCAGCACAAATGGCTCCCAGAGACGAACCTCCTGTCCAAGAGGAGCAGCAAAACTTGGCGTCATTAAGATGTTTAACATGA

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0000151 GO:0005575 GO:0005622 GO:0005623 GO:0006508 GO:0006511 GO:0006807 GO:0008150 GO:0008152 GO:0009056 GO:0009057 GO:0009987 GO:0010498 GO:0019538 GO:0019941 GO:0030163 GO:0032991 GO:0043161 GO:0043170 GO:0043632 GO:0044237 GO:0044238 GO:0044248 GO:0044257 GO:0044260 GO:0044265 GO:0044267 GO:0044424 GO:0044464 GO:0051603 GO:0071704 GO:1901564 GO:1901565 GO:1901575 GO:1902494 GO:1990234

KEGG Pathways

Metabolic & Signaling

No pathways identified.

Pfam Domains

Protein Families

F-box-like

Protein Analysis

392

Amino Acids

44.95

Weight (kDa)

9.1

Isoelectric Point (pI)

54.87

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
At5g52880_ARM	PF24104	6 - 104	1.4e-42	F-box protein At5g52880 ARM repeat
F-box-like	PF12937	115 - 158	2.3e-15	F-box-like
F-box	PF00646	116 - 155	3.6e-08	F-box domain

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

Style Settings

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

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Orthologous Genes (Group: OG0004452)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT5G52880
fragaria_vesca	FvH4_7g30600 FvH4_7g30600
malus_domestica	MD01G1211200.v1.1
prunus_persica	Prupe.2G291600_v2.0.a1 Prupe.2G303600_v2.0.a1 Prupe.2G303600_v2.0.a1 Prupe.2G303600_v2.0.a1 Prupe.2G303600_v2.0.a1 Prupe.2G303600_v2.0.a1 Prupe.2G303600_v2.0.a1 Prupe.2G304000_v2.0.a1
pyrus_communis	pycom01g22170
rosa_chinensis	RchiOBHm_Chr1g0378761 RchiOBHm_Chr1g0379101 RchiOBHm_Chr1g0379281 RchiOBHm_Chr1g0379501 RchiOBHm_Chr1g0379511
rosa_laevigata	RLG00000026397
rosa_multiflora	Rmu_sc0031430.1_g000003 Rmu_sc0031430.1_g000004
rosa_roxburghii	Rroxscaffold_4G00280130 Rroxscaffold_4G00280150
rosa_rugosa	Rorug01G0412300 Rorug01G0412400
rosa_samantha	Rh1AG434800 Rh1AG435100 Rh1BG392600 Rh1CG405300 Rh1DG423400
rosa_wichuraiana	Rw1G038010 Rw1G038020

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AccI	GTMKAC	1 cut(s)	532
AccII	CGCG	2 cut(s)	196, 315
AciI	CCGC	1 cut(s)	165
AclWI	GGATC	2 cut(s)	61, 1061
AcoI	YGGCCR	2 cut(s)	425, 875
AcsI	RAATTY	2 cut(s)	433, 711
AcuI	CTGAAG	1 cut(s)	774
AcyI	GRCGYC	1 cut(s)	1157
AfaI	GTAC	3 cut(s)	369, 933, 965
AfiI	CCNNNNNNNGG	2 cut(s)	834, 1053
AflIII	ACRYGT	1 cut(s)	370
AgsI	TTSAA	5 cut(s)	395, 508, 542, 580, 685
AjnI	CCWGG	1 cut(s)	384
AjuI	GAANNNNNNNTTGG	2 cut(s)	888, 920
AloI	GAACNNNNNNTCC	2 cut(s)	1116, 1148
AluBI	AGCT	5 cut(s)	88, 93, 215, 323, 983
AluI	AGCT	5 cut(s)	88, 93, 215, 323, 983
Alw21I	GWGCWC	1 cut(s)	90
Alw26I	GTCTC	5 cut(s)	144, 179, 211, 409, 1113
AlwI	GGATC	2 cut(s)	61, 1061
AoxI	GGCC	3 cut(s)	240, 425, 875
ApeKI	GCWGC	4 cut(s)	212, 440, 999, 1144
ApoI	RAATTY	2 cut(s)	433, 711
ArsI	GACNNNNNNTTYG	2 cut(s)	1116, 1148
Asp700I	GAANNNNTTC	1 cut(s)	680
AspLEI	GCGC	5 cut(s)	37, 110, 198, 315, 317
AspS9I	GGNCC	1 cut(s)	825
AsuHPI	GGTGA	5 cut(s)	154, 209, 726, 981, 1003
AvaII	GGWCC	1 cut(s)	825
BaeGI	GKGCMC	2 cut(s)	126, 913
BalI	TGGCCA	2 cut(s)	427, 877
BanII	GRGCYC	1 cut(s)	90
BbsI	GAAGAC	1 cut(s)	197
Bbv12I	GWGCWC	1 cut(s)	90
BbvI	GCAGC	4 cut(s)	224, 452, 986, 1156
BccI	CCATC	3 cut(s)	354, 952, 1048
BciT130I	CCWGG	1 cut(s)	386
BciVI	GTATCC	2 cut(s)	626, 849
BcoDI	GTCTC	5 cut(s)	144, 179, 211, 409, 1113
BfaI	CTAG	2 cut(s)	738, 834
BfmI	CTRYAG	1 cut(s)	637
BfoI	RGCGCY	1 cut(s)	111
BfuI	GTATCC	2 cut(s)	626, 849
BisI	GCNGC	4 cut(s)	213, 441, 1000, 1145
BlpI	GCTNAGC	1 cut(s)	89
BlsI	GCNGC	4 cut(s)	214, 442, 1001, 1146
Bme1390I	CCNGG	1 cut(s)	386
Bme18I	GGWCC	1 cut(s)	825
BmgT120I	GGNCC	1 cut(s)	825
BmiI	GGNNCC	2 cut(s)	826, 1113
BmrFI	CCNGG	1 cut(s)	386
BmrI	ACTGGG	1 cut(s)	837
BmsI	GCATC	2 cut(s)	850, 1059
BmuI	ACTGGG	1 cut(s)	837
BpiI	GAAGAC	1 cut(s)	197
BpmI	CTGGAG	2 cut(s)	119, 212
Bpu1102I	GCTNAGC	1 cut(s)	89
BsaBI	GATNNNNATC	1 cut(s)	1020
BsaHI	GRCGYC	1 cut(s)	1157
BsaJI	CCNNGG	2 cut(s)	428, 878
Bsc4I	CCNNNNNNNGG	2 cut(s)	834, 1053
Bse118I	RCCGGY	1 cut(s)	453
Bse1I	ACTGG	4 cut(s)	136, 528, 624, 843
Bse3DI	GCAATG	1 cut(s)	300
Bse8I	GATNNNNATC	1 cut(s)	1020
BseBI	CCWGG	1 cut(s)	386
BseDI	CCNNGG	2 cut(s)	428, 878
BseJI	GATNNNNATC	1 cut(s)	1020
BseLI	CCNNNNNNNGG	2 cut(s)	834, 1053
BseMI	GCAATG	1 cut(s)	300
BseMII	CTCAG	3 cut(s)	103, 115, 222
BseNI	ACTGG	4 cut(s)	136, 528, 624, 843
BsePI	GCGCGC	1 cut(s)	313
BseRI	GAGGAG	3 cut(s)	212, 215, 1154
BseSI	GKGCMC	2 cut(s)	126, 913
BseXI	GCAGC	4 cut(s)	224, 452, 986, 1156
Bsh1236I	CGCG	2 cut(s)	196, 315
BshFI	GGCC	3 cut(s)	242, 427, 877
BsiHKAI	GWGCWC	1 cut(s)	90
BsiSI	CCGG	1 cut(s)	454
BslFI	GGGAC	1 cut(s)	503
BslI	CCNNNNNNNGG	2 cut(s)	834, 1053
BsmAI	GTCTC	5 cut(s)	144, 179, 211, 409, 1113
BsmBI	CGTCTC	2 cut(s)	179, 1113
BsmFI	GGGAC	1 cut(s)	503
BsmI	GAATGC	1 cut(s)	295
BsnI	GGCC	3 cut(s)	242, 427, 877
Bsp1286I	GDGCHC	3 cut(s)	90, 126, 913
Bsp1407I	TGTACA	1 cut(s)	367
Bsp143I	GATC	3 cut(s)	53, 942, 1066
Bsp1720I	GCTNAGC	1 cut(s)	89
Bsp19I	CCATGG	1 cut(s)	428
BspACI	CCGC	1 cut(s)	165
BspANI	GGCC	3 cut(s)	242, 427, 877
BspCNI	CTCAG	3 cut(s)	102, 114, 221
BspFNI	CGCG	2 cut(s)	196, 315
BspLI	GGNNCC	2 cut(s)	826, 1113
BspPI	GGATC	2 cut(s)	61, 1061
BsrDI	GCAATG	1 cut(s)	300
BsrFI	RCCGGY	1 cut(s)	453
BsrGI	TGTACA	1 cut(s)	367
BsrI	ACTGG	4 cut(s)	136, 528, 624, 843
BssAI	RCCGGY	1 cut(s)	453
BssECI	CCNNGG	2 cut(s)	428, 878
BssHII	GCGCGC	1 cut(s)	313
BssMI	GATC	3 cut(s)	53, 942, 1066
BssNI	GRCGYC	1 cut(s)	1157
BssT1I	CCWWGG	2 cut(s)	428, 878
Bst2UI	CCWGG	1 cut(s)	386
Bst4CI	ACNGT	3 cut(s)	638, 809, 968
Bst6I	CTCTTC	2 cut(s)	327, 891
BstACI	GRCGYC	1 cut(s)	1157
BstAPI	GCANNNNNTGC	2 cut(s)	299, 860
BstAUI	TGTACA	1 cut(s)	367
BstC8I	GCNNGC	3 cut(s)	315, 325, 425
BstDEI	CTNAG	3 cut(s)	89, 101, 208
BstDSI	CCRYGG	1 cut(s)	428
BstENI	CCTNNNNNAGG	1 cut(s)	832
BstFNI	CGCG	2 cut(s)	196, 315
BstH2I	RGCGCY	1 cut(s)	111
BstHHI	GCGC	5 cut(s)	37, 110, 198, 315, 317
BstKTI	GATC	3 cut(s)	56, 945, 1069
BstMAI	GTCTC	5 cut(s)	144, 179, 211, 409, 1113
BstMBI	GATC	3 cut(s)	53, 942, 1066
BstMWI	GCNNNNNNNGC	4 cut(s)	209, 299, 860, 1109
BstNI	CCWGG	1 cut(s)	386
BstNSI	RCATGY	1 cut(s)	374
BstSCI	CCNGG	1 cut(s)	384
BstSFI	CTRYAG	1 cut(s)	637
BstSLI	GKGCMC	2 cut(s)	126, 913
BstUI	CGCG	2 cut(s)	196, 315
BstV1I	GCAGC	4 cut(s)	224, 452, 986, 1156
BstV2I	GAAGAC	1 cut(s)	197
BsuI	GTATCC	2 cut(s)	626, 849
BsuRI	GGCC	3 cut(s)	242, 427, 877
BtgI	CCRYGG	1 cut(s)	428
BtsI	GCAGTG	1 cut(s)	205
BtsIMutI	CAGTG	2 cut(s)	205, 814
Cac8I	GCNNGC	3 cut(s)	315, 325, 425
CfoI	GCGC	5 cut(s)	37, 110, 198, 315, 317
Cfr10I	RCCGGY	1 cut(s)	453
Cfr13I	GGNCC	1 cut(s)	825
CseI	GACGC	2 cut(s)	202, 1146
Csp6I	GTAC	3 cut(s)	368, 932, 964
CviAII	CATG	4 cut(s)	371, 429, 673, 1176
CviQI	GTAC	3 cut(s)	368, 932, 964
DdeI	CTNAG	3 cut(s)	89, 101, 208
DpnI	GATC	3 cut(s)	55, 944, 1068
DpnII	GATC	3 cut(s)	53, 942, 1066
DraI	TTTAAA	1 cut(s)	1036
EaeI	YGGCCR	2 cut(s)	425, 875
Eam1104I	CTCTTC	2 cut(s)	327, 891
EarI	CTCTTC	2 cut(s)	327, 891
Ecl136II	GAGCTC	1 cut(s)	88
Eco130I	CCWWGG	2 cut(s)	428, 878
Eco24I	GRGCYC	1 cut(s)	90
Eco47I	GGWCC	1 cut(s)	825
Eco53kI	GAGCTC	1 cut(s)	88
Eco57I	CTGAAG	1 cut(s)	774
EcoICRI	GAGCTC	1 cut(s)	88
EcoNI	CCTNNNNNAGG	1 cut(s)	832
EcoO109I	RGGNCCY	1 cut(s)	825
EcoRII	CCWGG	1 cut(s)	384
EcoT14I	CCWWGG	2 cut(s)	428, 878
EcoT38I	GRGCYC	1 cut(s)	90
ErhI	CCWWGG	2 cut(s)	428, 878
Esp3I	CGTCTC	2 cut(s)	179, 1113
FaeI	CATG	4 cut(s)	374, 432, 676, 1179
FalI	AAGNNNNNCTT	6 cut(s)	251, 283, 348, 380, 888, 920
FaqI	GGGAC	1 cut(s)	503
FatI	CATG	4 cut(s)	370, 428, 672, 1175
FblI	GTMKAC	1 cut(s)	532
Fnu4HI	GCNGC	4 cut(s)	213, 441, 1000, 1145
FriOI	GRGCYC	1 cut(s)	90
Fsp4HI	GCNGC	4 cut(s)	213, 441, 1000, 1145
FspBI	CTAG	2 cut(s)	738, 834
GlaI	GCGC	5 cut(s)	36, 109, 197, 314, 316
GluI	GCNGC	4 cut(s)	213, 441, 1000, 1145
GsuI	CTGGAG	2 cut(s)	119, 212
HaeII	RGCGCY	1 cut(s)	111
HaeIII	GGCC	3 cut(s)	242, 427, 877
HapII	CCGG	1 cut(s)	454
HgaI	GACGC	2 cut(s)	202, 1146
HhaI	GCGC	5 cut(s)	37, 110, 198, 315, 317
Hin1I	GRCGYC	1 cut(s)	1157
Hin1II	CATG	4 cut(s)	374, 432, 676, 1179
Hin6I	GCGC	5 cut(s)	35, 108, 196, 313, 315
HinP1I	GCGC	5 cut(s)	35, 108, 196, 313, 315
HincII	GTYRAC	1 cut(s)	751
HindII	GTYRAC	1 cut(s)	751
HinfI	GANTC	8 cut(s)	44, 130, 491, 767, 812, 883, 921, 1021
HpaII	CCGG	1 cut(s)	454
HphI	GGTGA	5 cut(s)	154, 209, 726, 981, 1003
Hpy166II	GTNNAC	3 cut(s)	533, 751, 964
Hpy188I	TCNGA	4 cut(s)	104, 717, 793, 817
Hpy188III	TCNNGA	6 cut(s)	182, 229, 707, 925, 940, 953
Hpy8I	GTNNAC	3 cut(s)	533, 751, 964
HpyAV	CCTTC	2 cut(s)	188, 586
HpyCH4III	ACNGT	3 cut(s)	638, 809, 968
HpyCH4IV	ACGT	1 cut(s)	479
HpyCH4V	TGCA	7 cut(s)	81, 293, 440, 648, 854, 1002, 1050
HpyF10VI	GCNNNNNNNGC	4 cut(s)	209, 299, 860, 1109
HpyF3I	CTNAG	3 cut(s)	89, 101, 208
HpySE526I	ACGT	1 cut(s)	479
Hsp92I	GRCGYC	1 cut(s)	1157
Hsp92II	CATG	4 cut(s)	374, 432, 676, 1179
HspAI	GCGC	5 cut(s)	35, 108, 196, 313, 315
Kzo9I	GATC	3 cut(s)	53, 942, 1066
LmnI	GCTCC	2 cut(s)	1117, 1141
Lsp1109I	GCAGC	4 cut(s)	224, 452, 986, 1156
LweI	GCATC	2 cut(s)	850, 1059
MaeI	CTAG	2 cut(s)	738, 834
MaeII	ACGT	1 cut(s)	479
MaeIII	GTNAC	1 cut(s)	274
MalI	GATC	3 cut(s)	55, 944, 1068
MboI	GATC	3 cut(s)	53, 942, 1066
MboII	GAAGA	9 cut(s)	139, 202, 274, 344, 554, 776, 777, 780, 908
MfeI	CAATTG	2 cut(s)	11, 654
MhlI	GDGCHC	3 cut(s)	90, 126, 913
MlsI	TGGCCA	2 cut(s)	427, 877
MluNI	TGGCCA	2 cut(s)	427, 877
MlyI	GAGTC	1 cut(s)	485
MmeI	TCCRAC	1 cut(s)	741
Mox20I	TGGCCA	2 cut(s)	427, 877
MroXI	GAANNNNTTC	1 cut(s)	680
MscI	TGGCCA	2 cut(s)	427, 877
MseI	TTAA	6 cut(s)	95, 617, 870, 1035, 1163, 1172
MslI	CAYNNNNRTG	3 cut(s)	891, 1016, 1165
Msp20I	TGGCCA	2 cut(s)	427, 877
MspI	CCGG	1 cut(s)	454
MspR9I	CCNGG	1 cut(s)	386
MunI	CAATTG	2 cut(s)	11, 654
Mva1269I	GAATGC	1 cut(s)	295
MvaI	CCWGG	1 cut(s)	386
MvnI	CGCG	2 cut(s)	196, 315
MwoI	GCNNNNNNNGC	4 cut(s)	209, 299, 860, 1109
NcoI	CCATGG	1 cut(s)	428
NdeII	GATC	3 cut(s)	53, 942, 1066
NlaIII	CATG	4 cut(s)	374, 432, 676, 1179
NlaIV	GGNNCC	2 cut(s)	826, 1113
NspI	RCATGY	1 cut(s)	374
PauI	GCGCGC	1 cut(s)	313
PciI	ACATGT	1 cut(s)	370
PctI	GAATGC	1 cut(s)	295
PdmI	GAANNNNTTC	1 cut(s)	680
PfeI	GAWTC	7 cut(s)	44, 130, 767, 812, 883, 921, 1021
PfoI	TCCNGGA	1 cut(s)	384
PkrI	GCNGC	4 cut(s)	214, 442, 1001, 1146
PleI	GAGTC	1 cut(s)	485
PpsI	GAGTC	1 cut(s)	485
PpuMI	RGGWCCY	1 cut(s)	825
PscI	ACATGT	1 cut(s)	370
Psp124BI	GAGCTC	1 cut(s)	90
Psp5II	RGGWCCY	1 cut(s)	825
Psp6I	CCWGG	1 cut(s)	384
PspGI	CCWGG	1 cut(s)	384
PspN4I	GGNNCC	2 cut(s)	826, 1113
PspPI	GGNCC	1 cut(s)	825
PspPPI	RGGWCCY	1 cut(s)	825
PteI	GCGCGC	1 cut(s)	313
RsaI	GTAC	3 cut(s)	369, 933, 965
RsaNI	GTAC	3 cut(s)	368, 932, 964
RseI	CAYNNNNRTG	3 cut(s)	891, 1016, 1165
SacI	GAGCTC	1 cut(s)	90
SaqAI	TTAA	6 cut(s)	95, 617, 870, 1035, 1163, 1172
SatI	GCNGC	4 cut(s)	213, 441, 1000, 1145
Sau3AI	GATC	3 cut(s)	53, 942, 1066
Sau96I	GGNCC	1 cut(s)	825
SchI	GAGTC	1 cut(s)	485
ScrFI	CCNGG	1 cut(s)	386
SduI	GDGCHC	3 cut(s)	90, 126, 913
SfaNI	GCATC	2 cut(s)	850, 1059
SfcI	CTRYAG	1 cut(s)	637
SinI	GGWCC	1 cut(s)	825
SmiMI	CAYNNNNRTG	3 cut(s)	891, 1016, 1165
SsiI	CCGC	1 cut(s)	165
SspMI	CTAG	2 cut(s)	738, 834
SstI	GAGCTC	1 cut(s)	90
StyD4I	CCNGG	1 cut(s)	384
StyI	CCWWGG	2 cut(s)	428, 878
TaaI	ACNGT	3 cut(s)	638, 809, 968
TaiI	ACGT	1 cut(s)	482
TaqI	TCGA	1 cut(s)	666
TatI	WGTACW	2 cut(s)	367, 963
TfiI	GAWTC	7 cut(s)	44, 130, 767, 812, 883, 921, 1021
Tru1I	TTAA	6 cut(s)	95, 617, 870, 1035, 1163, 1172
Tru9I	TTAA	6 cut(s)	95, 617, 870, 1035, 1163, 1172
TscAI	CASTG	2 cut(s)	205, 814
TseI	GCWGC	4 cut(s)	212, 440, 999, 1144
TspDTI	ATGAA	6 cut(s)	203, 594, 689, 875, 909, 1034
TspRI	CASTG	2 cut(s)	205, 814
VpaK11BI	GGWCC	1 cut(s)	825
XagI	CCTNNNNNAGG	1 cut(s)	832
XapI	RAATTY	2 cut(s)	433, 711
XceI	RCATGY	1 cut(s)	374
XmiI	GTMKAC	1 cut(s)	532
XmnI	GAANNNNTTC	1 cut(s)	680
XspI	CTAG	2 cut(s)	738, 834

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.