Basic Information

Type: gene

Biological Identity

Species

arabidopsis_thaliana

Chromosome

Orthogroup ID

OG0003116

Physical Location & Seq

Genomic Coordinates Reverse (-)

7682584 .. 7685662

Gene Structure 3079 bp

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UTR

Exon/CDS

Intron

Transcript / Protein ID

AT1G21890.1

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1170 bp

ATGGGGAGAGGGTTAATGAATAGTTTGAAACCATACTTAGCAATGATATCTATGCAGTTTGGTTATGCCGGTATGTACATAATCACCATGGTCTCTCTTAAGCATGGCATGAACCATTACGTCCTAGCCGTTTATCGCCATGCAATTGCCACTGCCGTCATCGCTCCATTTGCTCTTTTCCATGAAAGGAAAATAAGGCCCAAGATGACGTTCCGAATATTCCTCCAAATTGCGCTGCTCGGTTTTATTGAGCCGGTGCTTGATCAGAACCTCTACTACGTCGGGATGACTTACACGTCAGCAACTTTCGCTTCTGCTACTGCTAATGTCCTTCCGGCCATCACCTTCGTCTTGGCCATTATTTTCAGGTTAGAAAGCGTGAACTTTAAGAAGGTACGAAGCATAGCCAAAGTTGTAGGAACGGTGATCACAGTCTCCGGAGCACTTCTCATGACTCTCTACAAGGGTCCAATAGTTGACTTTATCCGATTCGGCGGTGGAGGAGGAGGAGGTAGTGATGGTGCAGGAGGATCCCACGGTGGTGCAGGAGCGGCAGCGATGGACAAACACTGGATTCCGGGAACACTTATGCTGTTGGGAAGAACTTTTGGTTGGGCCGGTTTCTTCATCCTACAATCGTTTACACTGAAGCAGTACCCAGCTGAGCTGTCATTAACGACGTTAATATGTTTAATGGGAACGTTAGAAGGAACCGCTGTTTCATTGGTAACGGTACGTGACTTGAGTGCTTGGAAAATCGGCTTCGACTCTAATCTCTTCGCCGCTGCTTACTCCGGGGTGATTTGTTCGGGAGTGGCGTATTACGTGCAAGGAGTAGTAATGAGAGAAAGAGGACCAGTTTTTGTTGCGACATTTAATCCACTTTGTGTCGTTATAACTGCTGCTCTTGGTGTTGTTGTCTTGTCTGAAAGCATTCATCTCGGAAGTGTGATTGGAACGCTATTTATAATCGTGGGCCTATACACTGTTGTATGGGGTAAAGGCAAAGACAAAAGAATGACGGATGATGACGAAGATTGCAAAGGACTTCCGATTAAAAGTCCGGTTAAACCGGTAGATACCGGTAAAGGCTTAGCCGCAGAACTGGAGATGAAATCAAAGGAAGGTCAAGAGGCAAAGGCTACTACTACTACTCAAGTTGAGATTTGA

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0003333 GO:0003674 GO:0005215 GO:0005342 GO:0005575 GO:0005623 GO:0005886 GO:0006810 GO:0006811 GO:0006820 GO:0006865 GO:0008150 GO:0008509 GO:0008514 GO:0015075 GO:0015171 GO:0015179 GO:0015318 GO:0015562 GO:0015711 GO:0015807 GO:0015849 GO:0016020 GO:0022857 GO:0032973 GO:0034220 GO:0034639 GO:0042592 GO:0043090 GO:0044464 GO:0046942 GO:0046943 GO:0048878 GO:0050801 GO:0051179 GO:0051234 GO:0055081 GO:0055085 GO:0065007 GO:0065008 GO:0071702 GO:0071705 GO:0071944 GO:0080144 GO:0098656 GO:0140115 GO:1902475 GO:1903825 GO:1905039

KEGG Pathways

Metabolic & Signaling

No pathways identified.

Pfam Domains

Protein Families

EamA

Protein Analysis

389

Amino Acids

41.71

Weight (kDa)

9.26

Isoelectric Point (pI)

23.15

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
EamA	PF00892	12 - 151	6.5e-13	EamA-like transporter family
EamA	PF00892	194 - 331	1.3e-09	EamA-like transporter family

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

Style Settings

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

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Orthologous Genes (Group: OG0003116)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT1G21890 AT1G21890 AT1G44800 AT4G08300
fragaria_vesca	FvH4_2g26691 FvH4_2g26691 FvH4_2g26691 FvH4_2g26700
malus_domestica	MD00G1157200.v1.1 MD15G1351700.v1.1 MD15G1351800.v1.1
prunus_persica	Prupe.1G500400_v2.0.a1 Prupe.1G500400_v2.0.a1 Prupe.1G500500_v2.0.a1
pyrus_communis	pycom08g14190 pycom15g31510
rosa_chinensis	RchiOBHm_Chr6g0295541 RchiOBHm_Chr6g0295571
rosa_laevigata	RLG00000011789 RLG00000011792
rosa_multiflora	Rmu_sc0005000.1_g000009 Rmu_sc0005000.1_g000012
rosa_roxburghii	Rroxscaffold_7G00172360 Rroxscaffold_7G00172380
rosa_rugosa	Rorug06G0251800 Rorug06G0251900 Rorug06G0252000 Rorug06G0252100
rosa_samantha	Rh6AG365000 Rh6AG365200 Rh6BG373400 Rh6CG379600 Rh6CG379800 Rh6DG366100 Rh6DG366400
rosa_wichuraiana	Rw6G031880 Rw6G031890

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AanI	TTATAA	2 cut(s)	896, 968
AasI	GACNNNNNNGTC	1 cut(s)	295
AccBSI	CCGCTC	1 cut(s)	551
AccIII	TCCGGA	1 cut(s)	437
AciI	CCGC	5 cut(s)	495, 551, 714, 783, 1098
AclI	AACGTT	1 cut(s)	701
AclWI	GGATC	2 cut(s)	525, 538
AcoI	YGGCCR	2 cut(s)	336, 354
AcuI	CTGAAG	1 cut(s)	668
AdeI	CACNNNGTG	1 cut(s)	887
AfaI	GTAC	4 cut(s)	77, 396, 656, 735
AflII	CTTAAG	1 cut(s)	98
AflIII	ACRYGT	1 cut(s)	294
AgeI	ACCGGT	2 cut(s)	1072, 1082
AgsI	TTSAA	1 cut(s)	28
AjiI	CACGTC	1 cut(s)	297
AjuI	GAANNNNNNNTTGG	4 cut(s)	194, 226, 595, 627
AleI	CACNNNNGTG	1 cut(s)	540
AluBI	AGCT	2 cut(s)	662, 667
AluI	AGCT	2 cut(s)	662, 667
Alw21I	GWGCWC	1 cut(s)	445
Alw26I	GTCTC	2 cut(s)	97, 439
AlwI	GGATC	2 cut(s)	525, 538
Aor13HI	TCCGGA	1 cut(s)	437
AoxI	GGCC	5 cut(s)	197, 336, 354, 615, 976
ApeKI	GCWGC	4 cut(s)	235, 554, 785, 902
AsiGI	ACCGGT	2 cut(s)	1072, 1082
Asp700I	GAANNNNTTC	1 cut(s)	933
AspLEI	GCGC	1 cut(s)	235
AspS9I	GGNCC	5 cut(s)	198, 467, 615, 854, 976
AsuC2I	CCSGG	2 cut(s)	579, 796
AsuHPI	GGTGA	4 cut(s)	76, 334, 436, 811
AvaII	GGWCC	2 cut(s)	467, 854
BalI	TGGCCA	1 cut(s)	356
BamHI	GGATCC	1 cut(s)	530
Bbv12I	GWGCWC	1 cut(s)	445
BbvI	GCAGC	4 cut(s)	222, 566, 772, 889
BccI	CCATC	3 cut(s)	347, 512, 553
BceAI	ACGGC	2 cut(s)	113, 140
BcgI	CGANNNNNNTGC	2 cut(s)	922, 956
BclI	TGATCA	2 cut(s)	262, 426
BcnI	CCSGG	2 cut(s)	579, 796
BcoDI	GTCTC	2 cut(s)	97, 439
BfaI	CTAG	1 cut(s)	125
BfrI	CTTAAG	1 cut(s)	98
BisI	GCNGC	7 cut(s)	236, 552, 555, 783, 786, 903, 1098
BlpI	GCTNAGC	2 cut(s)	663, 1093
BlsI	GCNGC	7 cut(s)	237, 553, 556, 784, 787, 904, 1099
Bme1390I	CCNGG	2 cut(s)	579, 796
Bme18I	GGWCC	2 cut(s)	467, 854
BmgBI	CACGTC	1 cut(s)	297
BmgT120I	GGNCC	5 cut(s)	198, 467, 615, 854, 976
BmiI	GGNNCC	3 cut(s)	468, 532, 712
BmrFI	CCNGG	2 cut(s)	579, 796
BplI	GAGNNNNNCTC	2 cut(s)	432, 464
BpmI	CTGGAG	1 cut(s)	1127
Bpu1102I	GCTNAGC	2 cut(s)	663, 1093
BpuEI	CTTGAG	2 cut(s)	763, 1140
BpuMI	CCSGG	2 cut(s)	579, 796
BsaAI	YACGTR	2 cut(s)	737, 826
BsaI	GGTCTC	1 cut(s)	97
BsaJI	CCNNGG	3 cut(s)	87, 535, 795
BsaWI	WCCGGW	4 cut(s)	437, 1063, 1072, 1082
Bse118I	RCCGGY	5 cut(s)	68, 253, 617, 1072, 1082
Bse1I	ACTGG	3 cut(s)	575, 857, 1110
Bse3DI	GCAATG	1 cut(s)	48
BseAI	TCCGGA	1 cut(s)	437
BseDI	CCNNGG	3 cut(s)	87, 535, 795
BseGI	GGATG	3 cut(s)	291, 627, 1030
BseMI	GCAATG	1 cut(s)	48
BseMII	CTCAG	1 cut(s)	654
BseNI	ACTGG	3 cut(s)	575, 857, 1110
BseRI	GAGGAG	3 cut(s)	516, 519, 522
BseXI	GCAGC	4 cut(s)	222, 566, 772, 889
BseYI	CCCAGC	1 cut(s)	658
BsgI	GTGCAG	2 cut(s)	543, 564
BshFI	GGCC	5 cut(s)	199, 338, 356, 617, 978
BshTI	ACCGGT	2 cut(s)	1072, 1082
BsiHKAI	GWGCWC	1 cut(s)	445
BsmAI	GTCTC	2 cut(s)	97, 439
BsmI	GAATGC	1 cut(s)	933
BsnI	GGCC	5 cut(s)	199, 338, 356, 617, 978
Bso31I	GGTCTC	1 cut(s)	97
Bsp1286I	GDGCHC	1 cut(s)	445
Bsp13I	TCCGGA	1 cut(s)	437
Bsp1407I	TGTACA	1 cut(s)	75
Bsp143I	GATC	3 cut(s)	262, 426, 530
Bsp1720I	GCTNAGC	2 cut(s)	663, 1093
Bsp19I	CCATGG	1 cut(s)	87
BspACI	CCGC	5 cut(s)	495, 551, 714, 783, 1098
BspANI	GGCC	5 cut(s)	199, 338, 356, 617, 978
BspCNI	CTCAG	1 cut(s)	655
BspEI	TCCGGA	1 cut(s)	437
BspHI	TCATGA	1 cut(s)	450
BspLI	GGNNCC	3 cut(s)	468, 532, 712
BspPI	GGATC	2 cut(s)	525, 538
BspTI	CTTAAG	1 cut(s)	98
BspTNI	GGTCTC	1 cut(s)	97
BsrBI	CCGCTC	1 cut(s)	551
BsrDI	GCAATG	1 cut(s)	48
BsrFI	RCCGGY	5 cut(s)	68, 253, 617, 1072, 1082
BsrGI	TGTACA	1 cut(s)	75
BsrI	ACTGG	3 cut(s)	575, 857, 1110
BssAI	RCCGGY	5 cut(s)	68, 253, 617, 1072, 1082
BssECI	CCNNGG	3 cut(s)	87, 535, 795
BssMI	GATC	3 cut(s)	262, 426, 530
BssT1I	CCWWGG	1 cut(s)	87
Bst4CI	ACNGT	5 cut(s)	424, 433, 539, 733, 988
Bst6I	CTCTTC	1 cut(s)	782
BstAFI	CTTAAG	1 cut(s)	98
BstAUI	TGTACA	1 cut(s)	75
BstBAI	YACGTR	2 cut(s)	737, 826
BstDEI	CTNAG	3 cut(s)	37, 663, 1093
BstDSI	CCRYGG	2 cut(s)	87, 535
BstF5I	GGATG	3 cut(s)	291, 627, 1030
BstHHI	GCGC	1 cut(s)	235
BstKTI	GATC	3 cut(s)	265, 429, 533
BstMAI	GTCTC	2 cut(s)	97, 439
BstMBI	GATC	3 cut(s)	262, 426, 530
BstMWI	GCNNNNNNNGC	4 cut(s)	161, 170, 308, 551
BstSCI	CCNGG	2 cut(s)	577, 794
BstV1I	GCAGC	4 cut(s)	222, 566, 772, 889
BstX2I	RGATCY	1 cut(s)	530
BstYI	RGATCY	1 cut(s)	530
BsuRI	GGCC	5 cut(s)	199, 338, 356, 617, 978
BtgI	CCRYGG	2 cut(s)	87, 535
BtgZI	GCGATG	2 cut(s)	145, 572
BtrI	CACGTC	1 cut(s)	297
BtsCI	GGATG	3 cut(s)	291, 627, 1030
BtsI	GCAGTG	1 cut(s)	150
BtsIMutI	CAGTG	4 cut(s)	150, 568, 644, 984
CciI	TCATGA	1 cut(s)	450
CfoI	GCGC	1 cut(s)	235
Cfr10I	RCCGGY	5 cut(s)	68, 253, 617, 1072, 1082
Cfr13I	GGNCC	5 cut(s)	198, 467, 615, 854, 976
Csp6I	GTAC	4 cut(s)	76, 395, 655, 734
CspAI	ACCGGT	2 cut(s)	1072, 1082
CviAII	CATG	6 cut(s)	88, 104, 109, 140, 182, 451
CviQI	GTAC	4 cut(s)	76, 395, 655, 734
DdeI	CTNAG	3 cut(s)	37, 663, 1093
DpnI	GATC	3 cut(s)	264, 428, 532
DpnII	GATC	3 cut(s)	262, 426, 530
DraIII	CACNNNGTG	1 cut(s)	887
DrdI	GACNNNNNNGTC	1 cut(s)	295
DseDI	GACNNNNNNGTC	1 cut(s)	295
EaeI	YGGCCR	2 cut(s)	336, 354
Eam1104I	CTCTTC	1 cut(s)	782
EarI	CTCTTC	1 cut(s)	782
Eco130I	CCWWGG	1 cut(s)	87
Eco31I	GGTCTC	1 cut(s)	97
Eco32I	GATATC	1 cut(s)	48
Eco47I	GGWCC	2 cut(s)	467, 854
Eco57I	CTGAAG	1 cut(s)	668
EcoRV	GATATC	1 cut(s)	48
EcoT14I	CCWWGG	1 cut(s)	87
ErhI	CCWWGG	1 cut(s)	87
FaeI	CATG	6 cut(s)	91, 107, 112, 143, 185, 454
FatI	CATG	6 cut(s)	87, 103, 108, 139, 181, 450
FbaI	TGATCA	2 cut(s)	262, 426
Fnu4HI	GCNGC	7 cut(s)	236, 552, 555, 783, 786, 903, 1098
FokI	GGATG	3 cut(s)	298, 614, 1037
Fsp4HI	GCNGC	7 cut(s)	236, 552, 555, 783, 786, 903, 1098
FspBI	CTAG	1 cut(s)	125
GlaI	GCGC	1 cut(s)	234
GluI	GCNGC	7 cut(s)	236, 552, 555, 783, 786, 903, 1098
GsaI	CCCAGC	1 cut(s)	662
GsuI	CTGGAG	1 cut(s)	1127
HaeIII	GGCC	5 cut(s)	199, 338, 356, 617, 978
HhaI	GCGC	1 cut(s)	235
Hin1II	CATG	6 cut(s)	91, 107, 112, 143, 185, 454
Hin6I	GCGC	1 cut(s)	233
HinP1I	GCGC	1 cut(s)	233
HincII	GTYRAC	1 cut(s)	478
HindII	GTYRAC	1 cut(s)	478
HinfI	GANTC	4 cut(s)	454, 489, 574, 767
HphI	GGTGA	4 cut(s)	76, 334, 436, 811
Hpy166II	GTNNAC	3 cut(s)	382, 478, 642
Hpy188I	TCNGA	6 cut(s)	215, 267, 488, 928, 944, 1053
Hpy188III	TCNNGA	5 cut(s)	283, 438, 451, 810, 1130
Hpy8I	GTNNAC	3 cut(s)	382, 478, 642
Hpy99I	CGWCG	2 cut(s)	284, 682
HpyAV	CCTTC	5 cut(s)	341, 355, 385, 701, 1118
HpyCH4III	ACNGT	5 cut(s)	424, 433, 539, 733, 988
HpyCH4IV	ACGT	8 cut(s)	120, 209, 279, 296, 680, 701, 736, 825
HpyCH4V	TGCA	6 cut(s)	55, 143, 524, 545, 829, 1041
HpyF10VI	GCNNNNNNNGC	4 cut(s)	161, 170, 308, 551
HpyF3I	CTNAG	3 cut(s)	37, 663, 1093
HpySE526I	ACGT	8 cut(s)	120, 209, 279, 296, 680, 701, 736, 825
Hsp92II	CATG	6 cut(s)	91, 107, 112, 143, 185, 454
HspAI	GCGC	1 cut(s)	233
Kpn2I	TCCGGA	1 cut(s)	437
Ksp22I	TGATCA	2 cut(s)	262, 426
Kzo9I	GATC	3 cut(s)	262, 426, 530
LmnI	GCTCC	3 cut(s)	169, 440, 548
Lsp1109I	GCAGC	4 cut(s)	222, 566, 772, 889
MaeI	CTAG	1 cut(s)	125
MaeII	ACGT	8 cut(s)	120, 209, 279, 296, 680, 701, 736, 825
MaeIII	GTNAC	2 cut(s)	727, 737
MalI	GATC	3 cut(s)	264, 428, 532
MbiI	CCGCTC	1 cut(s)	551
MboI	GATC	3 cut(s)	262, 426, 530
MboII	GAAGA	4 cut(s)	612, 616, 769, 1046
MfeI	CAATTG	1 cut(s)	144
MflI	RGATCY	1 cut(s)	530
MhlI	GDGCHC	1 cut(s)	445
MlsI	TGGCCA	1 cut(s)	356
MluCI	AATT	2 cut(s)	144, 228
MluNI	TGGCCA	1 cut(s)	356
MlyI	GAGTC	2 cut(s)	448, 761
MnlI	CCTC	9 cut(s)	233, 281, 494, 497, 500, 503, 521, 845, 1126
Mox20I	TGGCCA	1 cut(s)	356
MroI	TCCGGA	1 cut(s)	437
MroXI	GAANNNNTTC	1 cut(s)	933
MscI	TGGCCA	1 cut(s)	356
MseI	TTAA	9 cut(s)	14, 99, 387, 674, 683, 692, 876, 1056, 1068
MslI	CAYNNNNRTG	1 cut(s)	540
Msp20I	TGGCCA	1 cut(s)	356
MspA1I	CMGCKG	3 cut(s)	662, 716, 785
MspCI	CTTAAG	1 cut(s)	98
MspR9I	CCNGG	2 cut(s)	579, 796
MunI	CAATTG	1 cut(s)	144
Mva1269I	GAATGC	1 cut(s)	933
MwoI	GCNNNNNNNGC	4 cut(s)	161, 170, 308, 551
NciI	CCSGG	2 cut(s)	579, 796
NcoI	CCATGG	1 cut(s)	87
NdeII	GATC	3 cut(s)	262, 426, 530
NlaIII	CATG	6 cut(s)	91, 107, 112, 143, 185, 454
NlaIV	GGNNCC	3 cut(s)	468, 532, 712
NmuCI	GTSAC	1 cut(s)	737
OliI	CACNNNNGTG	1 cut(s)	540
PagI	TCATGA	1 cut(s)	450
PcsI	WCGNNNNNNNCGW	2 cut(s)	126, 815
PctI	GAATGC	1 cut(s)	933
PdmI	GAANNNNTTC	1 cut(s)	933
PfeI	GAWTC	2 cut(s)	489, 574
PfoI	TCCNGGA	1 cut(s)	577
PinAI	ACCGGT	2 cut(s)	1072, 1082
PkrI	GCNGC	7 cut(s)	237, 553, 556, 784, 787, 904, 1099
PleI	GAGTC	2 cut(s)	448, 761
PpsI	GAGTC	2 cut(s)	448, 761
Ppu21I	YACGTR	2 cut(s)	737, 826
PsiI	TTATAA	2 cut(s)	896, 968
Psp1406I	AACGTT	1 cut(s)	701
PspFI	CCCAGC	1 cut(s)	658
PspN4I	GGNNCC	3 cut(s)	468, 532, 712
PspPI	GGNCC	5 cut(s)	198, 467, 615, 854, 976
PsrI	GAACNNNNNNTAC	2 cut(s)	260, 292
PsuI	RGATCY	1 cut(s)	530
PvuII	CAGCTG	1 cut(s)	662
RsaI	GTAC	4 cut(s)	77, 396, 656, 735
RsaNI	GTAC	4 cut(s)	76, 395, 655, 734
RseI	CAYNNNNRTG	1 cut(s)	540
SaqAI	TTAA	9 cut(s)	14, 99, 387, 674, 683, 692, 876, 1056, 1068
SatI	GCNGC	7 cut(s)	236, 552, 555, 783, 786, 903, 1098
Sau3AI	GATC	3 cut(s)	262, 426, 530
Sau96I	GGNCC	5 cut(s)	198, 467, 615, 854, 976
SchI	GAGTC	2 cut(s)	448, 761
ScrFI	CCNGG	2 cut(s)	579, 796
SduI	GDGCHC	1 cut(s)	445
SinI	GGWCC	2 cut(s)	467, 854
SmiMI	CAYNNNNRTG	1 cut(s)	540
SmlI	CTYRAG	3 cut(s)	98, 742, 1155
SmoI	CTYRAG	3 cut(s)	98, 742, 1155
Sse9I	AATT	2 cut(s)	144, 228
SsiI	CCGC	5 cut(s)	495, 551, 714, 783, 1098
SspI	AATATT	1 cut(s)	219
SspMI	CTAG	1 cut(s)	125
StyD4I	CCNGG	2 cut(s)	577, 794
StyI	CCWWGG	1 cut(s)	87
TaaI	ACNGT	5 cut(s)	424, 433, 539, 733, 988
TaiI	ACGT	8 cut(s)	123, 212, 282, 299, 683, 704, 739, 828
TaqI	TCGA	1 cut(s)	765
TasI	AATT	2 cut(s)	144, 228
TatI	WGTACW	1 cut(s)	75
TauI	GCSGC	3 cut(s)	554, 785, 1100
TfiI	GAWTC	2 cut(s)	489, 574
Tru1I	TTAA	9 cut(s)	14, 99, 387, 674, 683, 692, 876, 1056, 1068
Tru9I	TTAA	9 cut(s)	14, 99, 387, 674, 683, 692, 876, 1056, 1068
TscAI	CASTG	4 cut(s)	157, 575, 651, 991
TseFI	GTSAC	1 cut(s)	737
TseI	GCWGC	4 cut(s)	235, 554, 785, 902
Tsp45I	GTSAC	1 cut(s)	737
TspDTI	ATGAA	7 cut(s)	32, 125, 198, 616, 711, 926, 1127
TspGWI	ACGGA	1 cut(s)	1037
TspRI	CASTG	4 cut(s)	157, 575, 651, 991
Vha464I	CTTAAG	1 cut(s)	98
VpaK11BI	GGWCC	2 cut(s)	467, 854
XmnI	GAANNNNTTC	1 cut(s)	933
XspI	CTAG	1 cut(s)	125

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.