MD06G1046500.v1.1

Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr06
OG0003640
Physical Location & Seq
Forward (+)
6299200 .. 6317088
17889 bp
Loading structure...
UTR
Exon/CDS
Intron
MD06G1046500.v1.1.491

Sequence Viewer

Length: 1056 bp
ATGGGTCGGAAGCAAAACGACCCAGAAGCCACCCATTACTTCTCTTTCGTCCTCCTCTTGGTGGTTTTGGTTTCCTGTGCTCTGGTCTACACATTCGTCTCTGCGGTGCTTAAACCCAATGATGCCTCTTCATTCTCGGACGGATCCTCGGAGCTCGAGTCGTTGACGTTGGTTGAGAAGGGCGGCGGCGTTGGGGTGGAGGGGGAGAGTGGCGCCGGGTGTTGCAGAGGGACTGAGAATTTGGAACTGTGGGGGGCTGCTGTGAAGTGGGGTTCTGAGTTTAAGTTCAGTTCTTCTGAGGAATGCTGCAAGGCGTGTAAATCCATGTGTACTGGGACTGATGGGCCTTGCTTGTGTGATTCTTGGGTGTTTTGTGGGAACAAGGAGGCTTGCGGCTCCAAATTTGGTGAGTGCTGGTTGAAGAAACAGAAAGATACATTGGCACCGGAGCGCCAGGAAGTAGGGGAAACAGTTATGTGGACTTCTGGACTCATCTTTGGGAAAGGAGAGGGCATTGTTGGCTTGGAAACAGAATATGGAACTCTTCATATAAAACTTTTCCCTGAATGTGCCCCTCATTCTGTAGCCTACATTCTTGAGTTGTTGGCATTGCGCCATTGTGCAGGCTGCCAGTTTTATCGTGCAGAGAGCCGAGGGCAATCATGGGATTCAGATGGAAACCACATAAAAAATACTCCTTTTGGCCCTCCATTTGCACTGGTTCAAGGAACACTAGAAGCTCAAGGAGGCACATTTAAGAAGATTCCGACTGAAGTTTGCCCGACCATTAGAAAGGGTTCTGTAGCATGGATTGGTTCTGGCCCAGAATTTTTTATAAGCCTAGCAAATCACGAAGAGTGGAAAAAAGACTACACTGTCTTTGCTTCTGTTCTTCCAGAAGACATGAGCATCGCCGAGAAAATTGCTCAACTTCCGACCACTCCAGAGGTTTGGAACAGTATCAACGTGACTGTCTTGGAAAAGCCCGTTCCCTTGCTTCTGCAAAGAATCAAGATGAGTCACGGAGATCTCACTGCAAACATGAAATCAAATTAA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
PAN_4 Pro_isomerase

Protein Analysis

352

Amino Acids

38.16

Weight (kDa)

5.32

Isoelectric Point (pI)

43.96

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
Pro_isomerase PF00160 173 - 326 4.4e-11 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AanI TTATAA 1 cut(s) 836
AasI GACNNNNNNGTC 1 cut(s) 875
AccB1I GGYRCC 2 cut(s) 212, 442
AccI GTMKAC 1 cut(s) 87
AciI CCGC 4 cut(s) 104, 183, 186, 393
AclWI GGATC 2 cut(s) 138, 151
AcsI RAATTY 3 cut(s) 238, 401, 827
AcuI CTGAAG 1 cut(s) 792
AcyI GRCGYC 1 cut(s) 213
AfaI GTAC 1 cut(s) 331
AfiI CCNNNNNNNGG 2 cut(s) 58, 61
AgsI TTSAA 2 cut(s) 421, 725
AjnI CCWGG 1 cut(s) 453
AjuI GAANNNNNNNTTGG 2 cut(s) 422, 454
AluBI AGCT 2 cut(s) 154, 740
AluI AGCT 2 cut(s) 154, 740
Alw21I GWGCWC 2 cut(s) 82, 156
Alw26I GTCTC 1 cut(s) 103
AlwI GGATC 2 cut(s) 138, 151
Ama87I CYCGRG 1 cut(s) 155
AoxI GGCC 3 cut(s) 344, 703, 820
ApeKI GCWGC 3 cut(s) 257, 306, 627
ApoI RAATTY 3 cut(s) 238, 401, 827
ArsI GACNNNNNNTTYG 2 cut(s) 223, 255
Asp700I GAANNNNTTC 1 cut(s) 796
AspLEI GCGC 3 cut(s) 215, 453, 615
AspS9I GGNCC 3 cut(s) 344, 704, 821
AsuC2I CCSGG 1 cut(s) 217
AsuHPI GGTGA 1 cut(s) 419
AvaI CYCGRG 1 cut(s) 155
BaeGI GKGCMC 1 cut(s) 574
BamHI GGATCC 1 cut(s) 143
BanI GGYRCC 2 cut(s) 212, 442
BanII GRGCYC 1 cut(s) 156
BbsI GAAGAC 1 cut(s) 906
Bbv12I GWGCWC 2 cut(s) 82, 156
BbvI GCAGC 3 cut(s) 244, 293, 614
BccI CCATC 2 cut(s) 335, 668
BcgI CGANNNNNNTGC 2 cut(s) 905, 939
BciT130I CCWGG 1 cut(s) 455
BcnI CCSGG 1 cut(s) 217
BcoDI GTCTC 1 cut(s) 103
BfaI CTAG 2 cut(s) 734, 842
BfmI CTRYAG 2 cut(s) 582, 801
BfoI RGCGCY 2 cut(s) 216, 454
BglII AGATCT 1 cut(s) 1027
BisI GCNGC 6 cut(s) 184, 187, 258, 307, 394, 628
BlsI GCNGC 6 cut(s) 185, 188, 259, 308, 395, 629
Bme1390I CCNGG 2 cut(s) 217, 455
BmeT110I CYCGRG 1 cut(s) 155
BmgT120I GGNCC 3 cut(s) 344, 704, 821
BmiI GGNNCC 4 cut(s) 145, 214, 397, 444
BmrFI CCNGG 2 cut(s) 217, 455
BmrI ACTGGG 1 cut(s) 342
BmsI GCATC 2 cut(s) 112, 918
BmuI ACTGGG 1 cut(s) 342
BpiI GAAGAC 1 cut(s) 906
BpmI CTGGAG 1 cut(s) 927
BpuEI CTTGAG 2 cut(s) 617, 726
BpuMI CCSGG 1 cut(s) 217
BsaHI GRCGYC 1 cut(s) 213
BsaJI CCNNGG 2 cut(s) 147, 652
BsaWI WCCGGW 1 cut(s) 445
BsaXI ACNNNNNCTCC 2 cut(s) 143, 173
Bsc4I CCNNNNNNNGG 2 cut(s) 58, 61
Bse1I ACTGG 3 cut(s) 337, 631, 723
Bse3DI GCAATG 1 cut(s) 608
BseBI CCWGG 1 cut(s) 455
BseDI CCNNGG 2 cut(s) 147, 652
BseLI CCNNNNNNNGG 2 cut(s) 58, 61
BseMI GCAATG 1 cut(s) 608
BseMII CTCAG 3 cut(s) 225, 267, 288
BseNI ACTGG 3 cut(s) 337, 631, 723
BseRI GAGGAG 1 cut(s) 44
BseSI GKGCMC 1 cut(s) 574
BseXI GCAGC 3 cut(s) 244, 293, 614
BsgI GTGCAG 2 cut(s) 642, 663
BshFI GGCC 3 cut(s) 346, 705, 822
BshNI GGYRCC 2 cut(s) 212, 442
BsiHKAI GWGCWC 2 cut(s) 82, 156
BsiHKCI CYCGRG 1 cut(s) 155
BsiSI CCGG 2 cut(s) 216, 446
BslFI GGGAC 2 cut(s) 244, 349
BslI CCNNNNNNNGG 2 cut(s) 58, 61
BsmAI GTCTC 1 cut(s) 103
BsmBI CGTCTC 1 cut(s) 103
BsmFI GGGAC 2 cut(s) 244, 349
BsmI GAATGC 1 cut(s) 308
BsnI GGCC 3 cut(s) 346, 705, 822
BsoBI CYCGRG 1 cut(s) 155
Bsp1286I GDGCHC 3 cut(s) 82, 156, 574
Bsp143I GATC 2 cut(s) 143, 1027
BspACI CCGC 4 cut(s) 104, 183, 186, 393
BspANI GGCC 3 cut(s) 346, 705, 822
BspCNI CTCAG 3 cut(s) 226, 268, 289
BspLI GGNNCC 4 cut(s) 145, 214, 397, 444
BspPI GGATC 2 cut(s) 138, 151
BspT107I GGYRCC 2 cut(s) 212, 442
BsrDI GCAATG 1 cut(s) 608
BsrI ACTGG 3 cut(s) 337, 631, 723
BssECI CCNNGG 2 cut(s) 147, 652
BssMI GATC 2 cut(s) 143, 1027
BssNI GRCGYC 1 cut(s) 213
Bst2UI CCWGG 1 cut(s) 455
Bst4CI ACNGT 5 cut(s) 249, 472, 877, 959, 973
Bst6I CTCTTC 3 cut(s) 133, 549, 849
BstACI GRCGYC 1 cut(s) 213
BstC8I GCNNGC 2 cut(s) 391, 625
BstDEI CTNAG 3 cut(s) 234, 276, 297
BstH2I RGCGCY 2 cut(s) 216, 454
BstHHI GCGC 3 cut(s) 215, 453, 615
BstKTI GATC 2 cut(s) 146, 1030
BstMAI GTCTC 1 cut(s) 103
BstMBI GATC 2 cut(s) 143, 1027
BstMWI GCNNNNNNNGC 1 cut(s) 519
BstNI CCWGG 1 cut(s) 455
BstSCI CCNGG 2 cut(s) 215, 453
BstSFI CTRYAG 2 cut(s) 582, 801
BstSLI GKGCMC 1 cut(s) 574
BstV1I GCAGC 3 cut(s) 244, 293, 614
BstV2I GAAGAC 1 cut(s) 906
BstX2I RGATCY 2 cut(s) 143, 1027
BstXI CCANNNNNNTGG 1 cut(s) 951
BstYI RGATCY 2 cut(s) 143, 1027
BsuRI GGCC 3 cut(s) 346, 705, 822
BtgZI GCGATG 1 cut(s) 895
BtsI GCAGTG 1 cut(s) 1032
BtsIMutI CAGTG 3 cut(s) 716, 873, 1032
Cac8I GCNNGC 2 cut(s) 391, 625
CfoI GCGC 3 cut(s) 215, 453, 615
Cfr13I GGNCC 3 cut(s) 344, 704, 821
Csp6I GTAC 1 cut(s) 330
CviAII CATG 5 cut(s) 325, 663, 807, 904, 1042
CviQI GTAC 1 cut(s) 330
DdeI CTNAG 3 cut(s) 234, 276, 297
DinI GGCGCC 1 cut(s) 214
DpnI GATC 2 cut(s) 145, 1029
DpnII GATC 2 cut(s) 143, 1027
DrdI GACNNNNNNGTC 1 cut(s) 875
DseDI GACNNNNNNGTC 1 cut(s) 875
Eam1104I CTCTTC 3 cut(s) 133, 549, 849
EarI CTCTTC 3 cut(s) 133, 549, 849
Ecl136II GAGCTC 1 cut(s) 154
Eco24I GRGCYC 1 cut(s) 156
Eco53kI GAGCTC 1 cut(s) 154
Eco57I CTGAAG 1 cut(s) 792
Eco88I CYCGRG 1 cut(s) 155
EcoICRI GAGCTC 1 cut(s) 154
EcoRII CCWGG 1 cut(s) 453
EcoT38I GRGCYC 1 cut(s) 156
EgeI GGCGCC 1 cut(s) 214
EheI GGCGCC 1 cut(s) 214
Esp3I CGTCTC 1 cut(s) 103
FaeI CATG 5 cut(s) 328, 666, 810, 907, 1045
FaqI GGGAC 2 cut(s) 244, 349
FatI CATG 5 cut(s) 324, 662, 806, 903, 1041
FblI GTMKAC 1 cut(s) 87
Fnu4HI GCNGC 6 cut(s) 184, 187, 258, 307, 394, 628
FriOI GRGCYC 1 cut(s) 156
Fsp4HI GCNGC 6 cut(s) 184, 187, 258, 307, 394, 628
FspBI CTAG 2 cut(s) 734, 842
GlaI GCGC 3 cut(s) 214, 452, 614
GluI GCNGC 6 cut(s) 184, 187, 258, 307, 394, 628
GsuI CTGGAG 1 cut(s) 927
HaeII RGCGCY 2 cut(s) 216, 454
HaeIII GGCC 3 cut(s) 346, 705, 822
HapII CCGG 2 cut(s) 216, 446
HhaI GCGC 3 cut(s) 215, 453, 615
Hin1I GRCGYC 1 cut(s) 213
Hin1II CATG 5 cut(s) 328, 666, 810, 907, 1045
Hin6I GCGC 3 cut(s) 213, 451, 613
HinP1I GCGC 3 cut(s) 213, 451, 613
HincII GTYRAC 1 cut(s) 165
HindII GTYRAC 1 cut(s) 165
HinfI GANTC 7 cut(s) 158, 359, 489, 668, 763, 1008, 1018
HpaII CCGG 2 cut(s) 216, 446
HphI GGTGA 1 cut(s) 419
Hpy166II GTNNAC 4 cut(s) 88, 165, 330, 480
Hpy188I TCNGA 8 cut(s) 9, 139, 151, 277, 298, 673, 768, 936
Hpy188III TCNNGA 6 cut(s) 486, 596, 851, 896, 944, 1012
Hpy8I GTNNAC 4 cut(s) 88, 165, 330, 480
HpyAV CCTTC 1 cut(s) 172
HpyCH4III ACNGT 5 cut(s) 249, 472, 877, 959, 973
HpyCH4IV ACGT 2 cut(s) 167, 966
HpyCH4V TGCA 7 cut(s) 225, 309, 623, 644, 716, 1003, 1037
HpyF10VI GCNNNNNNNGC 1 cut(s) 519
HpyF3I CTNAG 3 cut(s) 234, 276, 297
HpySE526I ACGT 2 cut(s) 167, 966
Hsp92I GRCGYC 1 cut(s) 213
Hsp92II CATG 5 cut(s) 328, 666, 810, 907, 1045
HspAI GCGC 3 cut(s) 213, 451, 613
KasI GGCGCC 1 cut(s) 212
Kzo9I GATC 2 cut(s) 143, 1027
LmnI GCTCC 3 cut(s) 151, 401, 448
Lsp1109I GCAGC 3 cut(s) 244, 293, 614
LweI GCATC 2 cut(s) 112, 918
MaeI CTAG 2 cut(s) 734, 842
MaeII ACGT 2 cut(s) 167, 966
MaeIII GTNAC 2 cut(s) 967, 1019
MalI GATC 2 cut(s) 145, 1029
MboI GATC 2 cut(s) 143, 1027
MboII GAAGA 8 cut(s) 120, 285, 433, 536, 772, 866, 884, 911
MflI RGATCY 2 cut(s) 143, 1027
MhlI GDGCHC 3 cut(s) 82, 156, 574
MluCI AATT 5 cut(s) 238, 401, 827, 921, 1051
Mly113I GGCGCC 1 cut(s) 213
MlyI GAGTC 3 cut(s) 167, 483, 1027
MmeI TCCRAC 2 cut(s) 791, 959
MroXI GAANNNNTTC 1 cut(s) 796
MseI TTAA 4 cut(s) 111, 282, 756, 1054
MspI CCGG 2 cut(s) 216, 446
MspR9I CCNGG 2 cut(s) 217, 455
Mva1269I GAATGC 1 cut(s) 308
MvaI CCWGG 1 cut(s) 455
MwoI GCNNNNNNNGC 1 cut(s) 519
NarI GGCGCC 1 cut(s) 213
NciI CCSGG 1 cut(s) 217
NdeII GATC 2 cut(s) 143, 1027
NlaIII CATG 5 cut(s) 328, 666, 810, 907, 1045
NlaIV GGNNCC 4 cut(s) 145, 214, 397, 444
NmeAIII GCCGAG 2 cut(s) 677, 940
NmuCI GTSAC 2 cut(s) 967, 1019
PaeR7I CTCGAG 1 cut(s) 155
PctI GAATGC 1 cut(s) 308
PdmI GAANNNNTTC 1 cut(s) 796
PfeI GAWTC 4 cut(s) 359, 668, 763, 1008
PkrI GCNGC 6 cut(s) 185, 188, 259, 308, 395, 629
PleI GAGTC 3 cut(s) 166, 483, 1026
PluTI GGCGCC 1 cut(s) 216
PpsI GAGTC 3 cut(s) 166, 483, 1026
PsiI TTATAA 1 cut(s) 836
Psp124BI GAGCTC 1 cut(s) 156
Psp6I CCWGG 1 cut(s) 453
PspGI CCWGG 1 cut(s) 453
PspN4I GGNNCC 4 cut(s) 145, 214, 397, 444
PspPI GGNCC 3 cut(s) 344, 704, 821
PspXI VCTCGAGB 1 cut(s) 155
PsuI RGATCY 2 cut(s) 143, 1027
RsaI GTAC 1 cut(s) 331
RsaNI GTAC 1 cut(s) 330
SacI GAGCTC 1 cut(s) 156
SaqAI TTAA 4 cut(s) 111, 282, 756, 1054
SatI GCNGC 6 cut(s) 184, 187, 258, 307, 394, 628
Sau3AI GATC 2 cut(s) 143, 1027
Sau96I GGNCC 3 cut(s) 344, 704, 821
SchI GAGTC 3 cut(s) 167, 483, 1027
ScrFI CCNGG 2 cut(s) 217, 455
SduI GDGCHC 3 cut(s) 82, 156, 574
SetI ASST 5 cut(s) 156, 170, 742, 951, 969
SfaNI GCATC 2 cut(s) 112, 918
SfcI CTRYAG 2 cut(s) 582, 801
SfoI GGCGCC 1 cut(s) 214
Sfr274I CTCGAG 1 cut(s) 155
SlaI CTCGAG 1 cut(s) 155
SmlI CTYRAG 3 cut(s) 155, 596, 741
SmoI CTYRAG 3 cut(s) 155, 596, 741
Sse9I AATT 5 cut(s) 238, 401, 827, 921, 1051
SsiI CCGC 4 cut(s) 104, 183, 186, 393
SspDI GGCGCC 1 cut(s) 212
SspMI CTAG 2 cut(s) 734, 842
SstI GAGCTC 1 cut(s) 156
StyD4I CCNGG 2 cut(s) 215, 453
TaaI ACNGT 5 cut(s) 249, 472, 877, 959, 973
TaiI ACGT 2 cut(s) 170, 969
TaqI TCGA 1 cut(s) 156
TasI AATT 5 cut(s) 238, 401, 827, 921, 1051
TatI WGTACW 1 cut(s) 329
TauI GCSGC 3 cut(s) 186, 189, 396
TfiI GAWTC 4 cut(s) 359, 668, 763, 1008
Tru1I TTAA 4 cut(s) 111, 282, 756, 1054
Tru9I TTAA 4 cut(s) 111, 282, 756, 1054
TscAI CASTG 3 cut(s) 723, 880, 1039
TseFI GTSAC 2 cut(s) 967, 1019
TseI GCWGC 3 cut(s) 257, 306, 627
Tsp45I GTSAC 2 cut(s) 967, 1019
TspDTI ATGAA 2 cut(s) 120, 536
TspGWI ACGGA 2 cut(s) 156, 1038
TspRI CASTG 3 cut(s) 723, 880, 1039
XapI RAATTY 3 cut(s) 238, 401, 827
XhoI CTCGAG 1 cut(s) 155
XmiI GTMKAC 1 cut(s) 87
XmnI GAANNNNTTC 1 cut(s) 796
XspI CTAG 2 cut(s) 734, 842
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.