MD03G1097000.v1.1

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr03
OG0000524
Physical Location & Seq
Forward (+)
8345517 .. 8345828
312 bp
Loading structure...
UTR
Exon/CDS
Intron
MD03G1097000.v1.1.491

Sequence Viewer

Length: 312 bp
ATGACAGGCCGTGGAAAGGGAGGCAAGGGCTTGGGCAAGGGAGGAGCGAAACGACATCGTAAGGTGCTGAGGGACAACATCCAGGGCATCACCAAGCCTGCGATTCGCCGTCTTGCTCGCAGAGGTGGCGTGAAGCGTATCAGCGGTCTGATCTACGAGGAGACCAGAGGGGTTCTCAAGATCTTTTTGGAGAACGTGATTCGTGATGCCGTGACCTACACCGAGCACGCCAGGAGGAAGACCGTGACCGCCATGGACGTGGTGTATGCTCTGAAGAGGCAGGGAAGGACCCTCTACGGTTTCGGGGGTTAA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
ko05034 ko05203 ko05322 map05034 map05203 map05322
Pfam Domains
Protein Families
CENP-T_C

Protein Analysis

104

Amino Acids

11.42

Weight (kDa)

11.48

Isoelectric Point (pI)

39.98

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
CENP-T_C PF15511 44 - 96 3.4e-08 Centromere kinetochore component CENP-T histone fold
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Orthologous Genes (Group: OG0000524)

Species Orthologous Gene IDs
arabidopsis_thaliana AT1G07660 AT1G07820 AT1G07820 AT2G28740 AT3G45930 AT3G46320 AT3G53730 AT5G59690 AT5G59970 AT5G59970
malus_domestica MD03G1097000.v1.1 MD03G1105400.v1.1 MD04G1124800.v1.1 MD06G1122500.v1.1 MD07G1184400.v1.1 MD07G1194500.v1.1 MD11G1143500.v1.1 MD12G1139800.v1.1 MD14G1139400.v1.1 MD15G1139200.v1.1
rosa_chinensis RchiOBHm_Chr1g0364991 RchiOBHm_Chr3g0467051 RchiOBHm_Chr5g0062221 RchiOBHm_Chr5g0063251 RchiOBHm_Chr5g0063281 RchiOBHm_Chr5g0063731 RchiOBHm_Chr7g0187711
rosa_laevigata RLG00000024533
rosa_multiflora Rmu_sc0004483.1_g000025 Rmu_sc0005045.1_g000017 Rmu_sc0005045.1_g000024 Rmu_sc0005638.1_g000003 Rmu_sc0042820.1_g000002 Rmu_sc0042820.1_g000003 Rmu_ssc0000112.1_g000021 Rmu_ssc0000309.1_g000047 Rmu_ssc0000409.1_g000022
rosa_roxburghii Rroxscaffold_1G00017140 Rroxscaffold_1G00017150 Rroxscaffold_1G00017430 Rroxscaffold_1G00017460 Rroxscaffold_4G00292020 Rroxscaffold_6G00413990
rosa_rugosa Rorug01G0318800 Rorug01G0329200 Rorug03G0085000 Rorug05G0347300 Rorug05G0355600 Rorug05G0355800 Rorug05G0358800 Rorug05G0358800 Rorug05G0358900 Rorug06G0483800
rosa_samantha Rh1AG327700 Rh1BG289000 Rh1CG305700 Rh1DG320500 Rh3AG133000 Rh3BG154000 Rh3CG154000 Rh3DG155100 Rh5AG407800 Rh5AG417800 Rh5BG421500 Rh5BG430300 Rh5BG433000 Rh5BG433200 Rh5CG445700 Rh5CG456200 Rh5CG456400 Rh5DG436500 Rh5DG443700 Rh5DG443900 Rh5DG446400 Rh5DG446600 Rh7BG090600 Rh7CG089600 Rh7DG091100
rosa_wichuraiana Rw1G029050 Rw3G012590 Rw5G038430 Rw5G039030 Rw5G039230 Rw5G039250 Rw7G007670

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AciI CCGC 2 cut(s) 144, 249
AcuI CTGAAG 1 cut(s) 293
AfiI CCNNNNNNNGG 1 cut(s) 16
AjiI CACGTC 1 cut(s) 259
AjnI CCWGG 2 cut(s) 81, 230
Alw21I GWGCWC 1 cut(s) 228
Alw26I GTCTC 1 cut(s) 155
AoxI GGCC 1 cut(s) 7
AspS9I GGNCC 1 cut(s) 288
AsuHPI GGTGA 1 cut(s) 82
AvaII GGWCC 1 cut(s) 288
BbsI GAAGAC 1 cut(s) 245
Bbv12I GWGCWC 1 cut(s) 228
BbvCI CCTCAGC 1 cut(s) 68
BceAI ACGGC 2 cut(s) 93, 194
BciT130I CCWGG 2 cut(s) 83, 232
BcoDI GTCTC 1 cut(s) 155
BglII AGATCT 1 cut(s) 180
Bme1390I CCNGG 2 cut(s) 83, 232
Bme18I GGWCC 1 cut(s) 288
BmgBI CACGTC 1 cut(s) 259
BmgT120I GGNCC 1 cut(s) 288
BmiI GGNNCC 1 cut(s) 290
BmrFI CCNGG 2 cut(s) 83, 232
BmsI GCATC 2 cut(s) 96, 196
BpiI GAAGAC 1 cut(s) 245
BplI GAGNNNNNCTC 2 cut(s) 159, 191
Bpu10I CCTNAGC 1 cut(s) 68
BpuEI CTTGAG 1 cut(s) 161
BsaI GGTCTC 1 cut(s) 155
BsaJI CCNNGG 3 cut(s) 10, 82, 252
Bsc4I CCNNNNNNNGG 1 cut(s) 16
BseBI CCWGG 2 cut(s) 83, 232
BseDI CCNNGG 3 cut(s) 10, 82, 252
BseGI GGATG 1 cut(s) 78
BseLI CCNNNNNNNGG 1 cut(s) 16
BseMII CTCAG 1 cut(s) 59
BseRI GAGGAG 2 cut(s) 57, 173
BshFI GGCC 1 cut(s) 9
BsiHKAI GWGCWC 1 cut(s) 228
BslFI GGGAC 1 cut(s) 86
BslI CCNNNNNNNGG 1 cut(s) 16
BsmAI GTCTC 1 cut(s) 155
BsmFI GGGAC 1 cut(s) 86
BsnI GGCC 1 cut(s) 9
Bso31I GGTCTC 1 cut(s) 155
Bsp1286I GDGCHC 1 cut(s) 228
Bsp143I GATC 2 cut(s) 150, 180
Bsp19I CCATGG 1 cut(s) 252
BspACI CCGC 2 cut(s) 144, 249
BspANI GGCC 1 cut(s) 9
BspCNI CTCAG 1 cut(s) 60
BspLI GGNNCC 1 cut(s) 290
BspTNI GGTCTC 1 cut(s) 155
BssECI CCNNGG 3 cut(s) 10, 82, 252
BssMI GATC 2 cut(s) 150, 180
BssT1I CCWWGG 1 cut(s) 252
Bst2UI CCWGG 2 cut(s) 83, 232
Bst4CI ACNGT 2 cut(s) 244, 299
Bst6I CTCTTC 1 cut(s) 269
BstC8I GCNNGC 3 cut(s) 99, 118, 228
BstDEI CTNAG 1 cut(s) 68
BstDSI CCRYGG 2 cut(s) 10, 252
BstF5I GGATG 1 cut(s) 78
BstKTI GATC 2 cut(s) 153, 183
BstMAI GTCTC 1 cut(s) 155
BstMBI GATC 2 cut(s) 150, 180
BstMWI GCNNNNNNNGC 1 cut(s) 126
BstNI CCWGG 2 cut(s) 83, 232
BstSCI CCNGG 2 cut(s) 81, 230
BstV2I GAAGAC 1 cut(s) 245
BstX2I RGATCY 1 cut(s) 180
BstXI CCANNNNNNTGG 1 cut(s) 259
BstYI RGATCY 1 cut(s) 180
BsuRI GGCC 1 cut(s) 9
BtgI CCRYGG 2 cut(s) 10, 252
BtrI CACGTC 1 cut(s) 259
BtsCI GGATG 1 cut(s) 78
Cac8I GCNNGC 3 cut(s) 99, 118, 228
Cfr13I GGNCC 1 cut(s) 288
CviAII CATG 1 cut(s) 253
CviJI RGCY 3 cut(s) 9, 30, 97
CviKI_1 RGCY 3 cut(s) 9, 30, 97
DdeI CTNAG 1 cut(s) 68
DpnI GATC 2 cut(s) 152, 182
DpnII GATC 2 cut(s) 150, 180
Eam1104I CTCTTC 1 cut(s) 269
EarI CTCTTC 1 cut(s) 269
Eco130I CCWWGG 1 cut(s) 252
Eco31I GGTCTC 1 cut(s) 155
Eco47I GGWCC 1 cut(s) 288
Eco57I CTGAAG 1 cut(s) 293
EcoO109I RGGNCCY 1 cut(s) 288
EcoRII CCWGG 2 cut(s) 81, 230
EcoT14I CCWWGG 1 cut(s) 252
ErhI CCWWGG 1 cut(s) 252
FaeI CATG 1 cut(s) 256
FaiI YATR 2 cut(s) 254, 267
FaqI GGGAC 1 cut(s) 86
FatI CATG 1 cut(s) 252
FokI GGATG 1 cut(s) 65
HaeIII GGCC 1 cut(s) 9
Hin1II CATG 1 cut(s) 256
HinfI GANTC 2 cut(s) 103, 199
HphI GGTGA 1 cut(s) 82
Hpy188I TCNGA 2 cut(s) 150, 273
Hpy188III TCNNGA 2 cut(s) 178, 203
HpyAV CCTTC 1 cut(s) 279
HpyCH4III ACNGT 2 cut(s) 244, 299
HpyCH4IV ACGT 2 cut(s) 195, 258
HpyF10VI GCNNNNNNNGC 1 cut(s) 126
HpyF3I CTNAG 1 cut(s) 68
HpySE526I ACGT 2 cut(s) 195, 258
Hsp92II CATG 1 cut(s) 256
Kzo9I GATC 2 cut(s) 150, 180
LmnI GCTCC 1 cut(s) 44
LpnPI CCDG 7 cut(s) 68, 95, 111, 178, 217, 244, 266
LweI GCATC 2 cut(s) 96, 196
MaeII ACGT 2 cut(s) 195, 258
MaeIII GTNAC 2 cut(s) 211, 244
MalI GATC 2 cut(s) 152, 182
MboI GATC 2 cut(s) 150, 180
MboII GAAGA 2 cut(s) 250, 286
MflI RGATCY 1 cut(s) 180
MhlI GDGCHC 1 cut(s) 228
MnlI CCTC 9 cut(s) 14, 35, 63, 116, 151, 161, 228, 270, 302
MseI TTAA 1 cut(s) 310
MslI CAYNNNNRTG 1 cut(s) 257
MspA1I CMGCKG 1 cut(s) 144
MspR9I CCNGG 2 cut(s) 83, 232
MvaI CCWGG 2 cut(s) 83, 232
MwoI GCNNNNNNNGC 1 cut(s) 126
NcoI CCATGG 1 cut(s) 252
NdeII GATC 2 cut(s) 150, 180
NlaIII CATG 1 cut(s) 256
NlaIV GGNNCC 1 cut(s) 290
NmuCI GTSAC 2 cut(s) 211, 244
PfeI GAWTC 2 cut(s) 103, 199
PpuMI RGGWCCY 1 cut(s) 288
Psp5II RGGWCCY 1 cut(s) 288
Psp6I CCWGG 2 cut(s) 81, 230
PspGI CCWGG 2 cut(s) 81, 230
PspN4I GGNNCC 1 cut(s) 290
PspPI GGNCC 1 cut(s) 288
PspPPI RGGWCCY 1 cut(s) 288
PsuI RGATCY 1 cut(s) 180
RseI CAYNNNNRTG 1 cut(s) 257
SaqAI TTAA 1 cut(s) 310
Sau3AI GATC 2 cut(s) 150, 180
Sau96I GGNCC 1 cut(s) 288
ScrFI CCNGG 2 cut(s) 83, 232
SduI GDGCHC 1 cut(s) 228
SetI ASST 5 cut(s) 66, 127, 198, 218, 261
SfaNI GCATC 2 cut(s) 96, 196
SinI GGWCC 1 cut(s) 288
SmiMI CAYNNNNRTG 1 cut(s) 257
SmlI CTYRAG 1 cut(s) 176
SmoI CTYRAG 1 cut(s) 176
SsiI CCGC 2 cut(s) 144, 249
StyD4I CCNGG 2 cut(s) 81, 230
StyI CCWWGG 1 cut(s) 252
TaaI ACNGT 2 cut(s) 244, 299
TaiI ACGT 2 cut(s) 198, 261
TfiI GAWTC 2 cut(s) 103, 199
Tru1I TTAA 1 cut(s) 310
Tru9I TTAA 1 cut(s) 310
TseFI GTSAC 2 cut(s) 211, 244
Tsp45I GTSAC 2 cut(s) 211, 244
VpaK11BI GGWCC 1 cut(s) 288
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.