MD07G1194500.v1.1

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr07
OG0000524
Physical Location & Seq
Reverse (-)
27389855 .. 27390166
312 bp
Loading structure...
UTR
Exon/CDS
Intron
MD07G1194500.v1.1.491

Sequence Viewer

Length: 312 bp
ATGACAGGCCGCGGGAAGGGAGGCAAGGGGCTGGGCAAGGGCGGAGCGAAACGGCACCGTAAGGTCCTCCGCGACAACATTCAGGGAATCACCAAGCCGGCAATTCGGAGACTGGCCAGAAGAGGTGGGGTGAAGAGAATCAGCGGCCTTATCTACGAGGAGACCAGAGGCGTCCTCAAGATCTTCTTGGAGAACGTGATTCGCGACGCTGTTACCTACACCGAGCACGCGCGGCGGAAGACGGTGACCGCAATGGACGTCGTCTACGCTCTCAAGAGGCAGGGCAGGACCCTGTACGGATTCGGGGGTTAA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
ko05034 ko05203 ko05322 map05034 map05203 map05322
Pfam Domains
Protein Families
CENP-T_C

Protein Analysis

104

Amino Acids

11.42

Weight (kDa)

11.48

Isoelectric Point (pI)

39.98

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
CENP-T_C PF15511 44 - 96 3.4e-08 Centromere kinetochore component CENP-T histone fold
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
iTOL Interactive Tree Of Life · Most popular EvolView Flexible annotations MEGA Desktop phylogenetics suite FigTree Desktop tree editor

Orthologous Genes (Group: OG0000524)

Species Orthologous Gene IDs
arabidopsis_thaliana AT1G07660 AT1G07820 AT1G07820 AT2G28740 AT3G45930 AT3G46320 AT3G53730 AT5G59690 AT5G59970 AT5G59970
malus_domestica MD03G1097000.v1.1 MD03G1105400.v1.1 MD04G1124800.v1.1 MD06G1122500.v1.1 MD07G1184400.v1.1 MD07G1194500.v1.1 MD11G1143500.v1.1 MD12G1139800.v1.1 MD14G1139400.v1.1 MD15G1139200.v1.1
rosa_chinensis RchiOBHm_Chr1g0364991 RchiOBHm_Chr3g0467051 RchiOBHm_Chr5g0062221 RchiOBHm_Chr5g0063251 RchiOBHm_Chr5g0063281 RchiOBHm_Chr5g0063731 RchiOBHm_Chr7g0187711
rosa_laevigata RLG00000024533
rosa_multiflora Rmu_sc0004483.1_g000025 Rmu_sc0005045.1_g000017 Rmu_sc0005045.1_g000024 Rmu_sc0005638.1_g000003 Rmu_sc0042820.1_g000002 Rmu_sc0042820.1_g000003 Rmu_ssc0000112.1_g000021 Rmu_ssc0000309.1_g000047 Rmu_ssc0000409.1_g000022
rosa_roxburghii Rroxscaffold_1G00017140 Rroxscaffold_1G00017150 Rroxscaffold_1G00017430 Rroxscaffold_1G00017460 Rroxscaffold_4G00292020 Rroxscaffold_6G00413990
rosa_rugosa Rorug01G0318800 Rorug01G0329200 Rorug03G0085000 Rorug05G0347300 Rorug05G0355600 Rorug05G0355800 Rorug05G0358800 Rorug05G0358800 Rorug05G0358900 Rorug06G0483800
rosa_samantha Rh1AG327700 Rh1BG289000 Rh1CG305700 Rh1DG320500 Rh3AG133000 Rh3BG154000 Rh3CG154000 Rh3DG155100 Rh5AG407800 Rh5AG417800 Rh5BG421500 Rh5BG430300 Rh5BG433000 Rh5BG433200 Rh5CG445700 Rh5CG456200 Rh5CG456400 Rh5DG436500 Rh5DG443700 Rh5DG443900 Rh5DG446400 Rh5DG446600 Rh7BG090600 Rh7CG089600 Rh7DG091100
rosa_wichuraiana Rw1G029050 Rw3G012590 Rw5G038430 Rw5G039030 Rw5G039230 Rw5G039250 Rw7G007670

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AatII GACGTC 1 cut(s) 261
AccB1I GGYRCC 1 cut(s) 54
AccI GTMKAC 1 cut(s) 264
AccII CGCG 5 cut(s) 12, 72, 204, 230, 232
AciI CCGC 8 cut(s) 10, 12, 42, 70, 144, 232, 235, 249
AcoI YGGCCR 1 cut(s) 114
AcyI GRCGYC 2 cut(s) 171, 258
AfaI GTAC 1 cut(s) 296
AfiI CCNNNNNNNGG 1 cut(s) 16
Alw21I GWGCWC 1 cut(s) 228
Alw26I GTCTC 2 cut(s) 103, 155
AoxI GGCC 3 cut(s) 7, 114, 145
AspLEI GCGC 1 cut(s) 232
AspS9I GGNCC 2 cut(s) 64, 288
AsuHPI GGTGA 3 cut(s) 82, 142, 256
AvaII GGWCC 2 cut(s) 64, 288
BalI TGGCCA 1 cut(s) 116
BanI GGYRCC 1 cut(s) 54
BbsI GAAGAC 1 cut(s) 245
Bbv12I GWGCWC 1 cut(s) 228
BceAI ACGGC 1 cut(s) 68
BcoDI GTCTC 2 cut(s) 103, 155
BglII AGATCT 1 cut(s) 180
BisI GCNGC 3 cut(s) 10, 145, 233
BlsI GCNGC 3 cut(s) 11, 146, 234
Bme18I GGWCC 2 cut(s) 64, 288
BmgT120I GGNCC 2 cut(s) 64, 288
BmiI GGNNCC 2 cut(s) 56, 290
BpiI GAAGAC 1 cut(s) 245
BplI GAGNNNNNCTC 2 cut(s) 159, 191
BpuEI CTTGAG 2 cut(s) 161, 257
BsaHI GRCGYC 2 cut(s) 171, 258
BsaI GGTCTC 1 cut(s) 155
BsaJI CCNNGG 1 cut(s) 10
Bsc4I CCNNNNNNNGG 1 cut(s) 16
Bse118I RCCGGY 1 cut(s) 97
Bse1I ACTGG 1 cut(s) 117
Bse3DI GCAATG 1 cut(s) 258
BseDI CCNNGG 1 cut(s) 10
BseLI CCNNNNNNNGG 1 cut(s) 16
BseMI GCAATG 1 cut(s) 258
BseNI ACTGG 1 cut(s) 117
BseRI GAGGAG 1 cut(s) 173
BseYI CCCAGC 1 cut(s) 31
Bsh1236I CGCG 5 cut(s) 12, 72, 204, 230, 232
BshFI GGCC 3 cut(s) 9, 116, 147
BshNI GGYRCC 1 cut(s) 54
BsiHKAI GWGCWC 1 cut(s) 228
BsiSI CCGG 1 cut(s) 98
BslI CCNNNNNNNGG 1 cut(s) 16
BsmAI GTCTC 2 cut(s) 103, 155
BsnI GGCC 3 cut(s) 9, 116, 147
Bso31I GGTCTC 1 cut(s) 155
Bsp1286I GDGCHC 1 cut(s) 228
Bsp143I GATC 1 cut(s) 180
Bsp68I TCGCGA 1 cut(s) 204
BspACI CCGC 8 cut(s) 10, 12, 42, 70, 144, 232, 235, 249
BspANI GGCC 3 cut(s) 9, 116, 147
BspFNI CGCG 5 cut(s) 12, 72, 204, 230, 232
BspLI GGNNCC 2 cut(s) 56, 290
BspT107I GGYRCC 1 cut(s) 54
BspTNI GGTCTC 1 cut(s) 155
BsrDI GCAATG 1 cut(s) 258
BsrFI RCCGGY 1 cut(s) 97
BsrI ACTGG 1 cut(s) 117
BssAI RCCGGY 1 cut(s) 97
BssECI CCNNGG 1 cut(s) 10
BssMI GATC 1 cut(s) 180
BssNI GRCGYC 2 cut(s) 171, 258
Bst4CI ACNGT 2 cut(s) 59, 244
Bst6I CTCTTC 2 cut(s) 115, 128
BstACI GRCGYC 2 cut(s) 171, 258
BstC8I GCNNGC 2 cut(s) 99, 228
BstDSI CCRYGG 1 cut(s) 10
BstEII GGTNACC 1 cut(s) 244
BstFNI CGCG 5 cut(s) 12, 72, 204, 230, 232
BstHHI GCGC 1 cut(s) 232
BstKTI GATC 1 cut(s) 183
BstMAI GTCTC 2 cut(s) 103, 155
BstMBI GATC 1 cut(s) 180
BstMWI GCNNNNNNNGC 1 cut(s) 232
BstPI GGTNACC 1 cut(s) 244
BstUI CGCG 5 cut(s) 12, 72, 204, 230, 232
BstV2I GAAGAC 1 cut(s) 245
BstX2I RGATCY 1 cut(s) 180
BstYI RGATCY 1 cut(s) 180
BsuRI GGCC 3 cut(s) 9, 116, 147
BtgI CCRYGG 1 cut(s) 10
BtuMI TCGCGA 1 cut(s) 204
Cac8I GCNNGC 2 cut(s) 99, 228
CfoI GCGC 1 cut(s) 232
Cfr10I RCCGGY 1 cut(s) 97
Cfr13I GGNCC 2 cut(s) 64, 288
Cfr42I CCGCGG 1 cut(s) 13
CseI GACGC 2 cut(s) 160, 215
Csp6I GTAC 1 cut(s) 295
CviJI RGCY 5 cut(s) 9, 31, 97, 116, 147
CviKI_1 RGCY 5 cut(s) 9, 31, 97, 116, 147
CviQI GTAC 1 cut(s) 295
DpnI GATC 1 cut(s) 182
DpnII GATC 1 cut(s) 180
EaeI YGGCCR 1 cut(s) 114
Eam1104I CTCTTC 2 cut(s) 115, 128
EarI CTCTTC 2 cut(s) 115, 128
EciI GGCGGA 2 cut(s) 57, 250
Eco31I GGTCTC 1 cut(s) 155
Eco47I GGWCC 2 cut(s) 64, 288
Eco91I GGTNACC 1 cut(s) 244
EcoO109I RGGNCCY 2 cut(s) 64, 288
EcoO65I GGTNACC 1 cut(s) 244
FalI AAGNNNNNCTT 2 cut(s) 170, 202
FauI CCCGC 1 cut(s) 5
FblI GTMKAC 1 cut(s) 264
Fnu4HI GCNGC 3 cut(s) 10, 145, 233
Fsp4HI GCNGC 3 cut(s) 10, 145, 233
GlaI GCGC 1 cut(s) 231
GluI GCNGC 3 cut(s) 10, 145, 233
GsaI CCCAGC 1 cut(s) 35
HaeIII GGCC 3 cut(s) 9, 116, 147
HapII CCGG 1 cut(s) 98
HgaI GACGC 2 cut(s) 160, 215
HhaI GCGC 1 cut(s) 232
Hin1I GRCGYC 2 cut(s) 171, 258
Hin6I GCGC 1 cut(s) 230
HinP1I GCGC 1 cut(s) 230
HinfI GANTC 4 cut(s) 87, 138, 199, 300
HpaII CCGG 1 cut(s) 98
HphI GGTGA 3 cut(s) 82, 142, 256
Hpy166II GTNNAC 1 cut(s) 265
Hpy188I TCNGA 1 cut(s) 108
Hpy188III TCNNGA 3 cut(s) 178, 203, 274
Hpy8I GTNNAC 1 cut(s) 265
Hpy99I CGWCG 2 cut(s) 209, 263
HpyAV CCTTC 1 cut(s) 10
HpyCH4III ACNGT 2 cut(s) 59, 244
HpyCH4IV ACGT 2 cut(s) 195, 258
HpyF10VI GCNNNNNNNGC 1 cut(s) 232
HpySE526I ACGT 2 cut(s) 195, 258
Hsp92I GRCGYC 2 cut(s) 171, 258
HspAI GCGC 1 cut(s) 230
KroI GCCGGC 1 cut(s) 97
KroNI GCCGGC 1 cut(s) 99
KspI CCGCGG 1 cut(s) 13
Kzo9I GATC 1 cut(s) 180
LmnI GCTCC 1 cut(s) 44
LpnPI CCDG 9 cut(s) 17, 68, 98, 111, 130, 178, 266, 271, 305
MaeII ACGT 2 cut(s) 195, 258
MaeIII GTNAC 2 cut(s) 211, 244
MalI GATC 1 cut(s) 182
MboI GATC 1 cut(s) 180
MboII GAAGA 4 cut(s) 132, 145, 175, 250
MflI RGATCY 1 cut(s) 180
MhlI GDGCHC 1 cut(s) 228
MlsI TGGCCA 1 cut(s) 116
MluCI AATT 1 cut(s) 102
MluNI TGGCCA 1 cut(s) 116
MnlI CCTC 7 cut(s) 14, 77, 116, 151, 161, 185, 270
Mox20I TGGCCA 1 cut(s) 116
MroNI GCCGGC 1 cut(s) 97
MscI TGGCCA 1 cut(s) 116
MseI TTAA 1 cut(s) 310
Msp20I TGGCCA 1 cut(s) 116
MspA1I CMGCKG 2 cut(s) 12, 144
MspI CCGG 1 cut(s) 98
MvnI CGCG 5 cut(s) 12, 72, 204, 230, 232
MwoI GCNNNNNNNGC 1 cut(s) 232
NaeI GCCGGC 1 cut(s) 99
NdeII GATC 1 cut(s) 180
NgoMIV GCCGGC 1 cut(s) 97
NlaIV GGNNCC 2 cut(s) 56, 290
NmuCI GTSAC 1 cut(s) 244
NruI TCGCGA 1 cut(s) 204
PcsI WCGNNNNNNNCGW 1 cut(s) 201
PdiI GCCGGC 1 cut(s) 99
PfeI GAWTC 4 cut(s) 87, 138, 199, 300
PflFI GACNNNGTC 1 cut(s) 260
PkrI GCNGC 3 cut(s) 11, 146, 234
PpuMI RGGWCCY 2 cut(s) 64, 288
Psp5II RGGWCCY 2 cut(s) 64, 288
PspEI GGTNACC 1 cut(s) 244
PspFI CCCAGC 1 cut(s) 31
PspN4I GGNNCC 2 cut(s) 56, 290
PspPI GGNCC 2 cut(s) 64, 288
PspPPI RGGWCCY 2 cut(s) 64, 288
PsuI RGATCY 1 cut(s) 180
PsyI GACNNNGTC 1 cut(s) 260
RruI TCGCGA 1 cut(s) 204
RsaI GTAC 1 cut(s) 296
RsaNI GTAC 1 cut(s) 295
SacII CCGCGG 1 cut(s) 13
SaqAI TTAA 1 cut(s) 310
SatI GCNGC 3 cut(s) 10, 145, 233
Sau3AI GATC 1 cut(s) 180
Sau96I GGNCC 2 cut(s) 64, 288
SduI GDGCHC 1 cut(s) 228
SetI ASST 5 cut(s) 66, 127, 198, 218, 261
Sfr303I CCGCGG 1 cut(s) 13
SgrBI CCGCGG 1 cut(s) 13
SinI GGWCC 2 cut(s) 64, 288
SmlI CTYRAG 2 cut(s) 176, 272
SmoI CTYRAG 2 cut(s) 176, 272
Sse9I AATT 1 cut(s) 102
SsiI CCGC 8 cut(s) 10, 12, 42, 70, 144, 232, 235, 249
TaaI ACNGT 2 cut(s) 59, 244
TaiI ACGT 2 cut(s) 198, 261
TasI AATT 1 cut(s) 102
TauI GCSGC 3 cut(s) 12, 147, 235
TfiI GAWTC 4 cut(s) 87, 138, 199, 300
Tru1I TTAA 1 cut(s) 310
Tru9I TTAA 1 cut(s) 310
TseFI GTSAC 1 cut(s) 244
Tsp45I GTSAC 1 cut(s) 244
TspGWI ACGGA 1 cut(s) 312
Tth111I GACNNNGTC 1 cut(s) 260
VpaK11BI GGWCC 2 cut(s) 64, 288
XmiI GTMKAC 1 cut(s) 264
ZraI GACGTC 1 cut(s) 259
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.