MD03G1105400.v1.1

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr03
OG0000524
Physical Location & Seq
Reverse (-)
9035361 .. 9036057
697 bp
Loading structure...
UTR
Exon/CDS
Intron
MD03G1105400.v1.1.491

Sequence Viewer

Length: 312 bp
ATGACGGGACGTGGAAAGGGAGGCAAGGGACTGGGCAAGGGAGGAGCGAAGCGTCACCGTAAGGTCCTCCGCGACAACATCCAGGGCATCACCAAGCCGGCGATTCGCCGCCTGGCCCGCAGAGGCGGCGTGAAGCGAATCAGCGGCCTGATCTACGAAGAGACCCGCGGCGTCCTCAAGATCTTTCTCGAGAACGTGATTCGGGACGCCGTTACCTACACGGAGCACGCCAGGAGGAAGACGGTGACGGCGATGGACGTTGTTTACGCTCTCAAGAGGCAAGGCAGGACTCTGTACGGGTTTGGGGGTTAG
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
ko05034 ko05203 ko05322 map05034 map05203 map05322
Pfam Domains
Protein Families
CENP-T_C

Protein Analysis

104

Amino Acids

11.42

Weight (kDa)

11.48

Isoelectric Point (pI)

39.98

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
CENP-T_C PF15511 44 - 96 3.4e-08 Centromere kinetochore component CENP-T histone fold
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
iTOL Interactive Tree Of Life · Most popular EvolView Flexible annotations MEGA Desktop phylogenetics suite FigTree Desktop tree editor

Orthologous Genes (Group: OG0000524)

Species Orthologous Gene IDs
arabidopsis_thaliana AT1G07660 AT1G07820 AT1G07820 AT2G28740 AT3G45930 AT3G46320 AT3G53730 AT5G59690 AT5G59970 AT5G59970
malus_domestica MD03G1097000.v1.1 MD03G1105400.v1.1 MD04G1124800.v1.1 MD06G1122500.v1.1 MD07G1184400.v1.1 MD07G1194500.v1.1 MD11G1143500.v1.1 MD12G1139800.v1.1 MD14G1139400.v1.1 MD15G1139200.v1.1
rosa_chinensis RchiOBHm_Chr1g0364991 RchiOBHm_Chr3g0467051 RchiOBHm_Chr5g0062221 RchiOBHm_Chr5g0063251 RchiOBHm_Chr5g0063281 RchiOBHm_Chr5g0063731 RchiOBHm_Chr7g0187711
rosa_laevigata RLG00000024533
rosa_multiflora Rmu_sc0004483.1_g000025 Rmu_sc0005045.1_g000017 Rmu_sc0005045.1_g000024 Rmu_sc0005638.1_g000003 Rmu_sc0042820.1_g000002 Rmu_sc0042820.1_g000003 Rmu_ssc0000112.1_g000021 Rmu_ssc0000309.1_g000047 Rmu_ssc0000409.1_g000022
rosa_roxburghii Rroxscaffold_1G00017140 Rroxscaffold_1G00017150 Rroxscaffold_1G00017430 Rroxscaffold_1G00017460 Rroxscaffold_4G00292020 Rroxscaffold_6G00413990
rosa_rugosa Rorug01G0318800 Rorug01G0329200 Rorug03G0085000 Rorug05G0347300 Rorug05G0355600 Rorug05G0355800 Rorug05G0358800 Rorug05G0358800 Rorug05G0358900 Rorug06G0483800
rosa_samantha Rh1AG327700 Rh1BG289000 Rh1CG305700 Rh1DG320500 Rh3AG133000 Rh3BG154000 Rh3CG154000 Rh3DG155100 Rh5AG407800 Rh5AG417800 Rh5BG421500 Rh5BG430300 Rh5BG433000 Rh5BG433200 Rh5CG445700 Rh5CG456200 Rh5CG456400 Rh5DG436500 Rh5DG443700 Rh5DG443900 Rh5DG446400 Rh5DG446600 Rh7BG090600 Rh7CG089600 Rh7DG091100
rosa_wichuraiana Rw1G029050 Rw3G012590 Rw5G038430 Rw5G039030 Rw5G039230 Rw5G039250 Rw7G007670

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccII CGCG 2 cut(s) 72, 168
AciI CCGC 7 cut(s) 70, 109, 118, 126, 144, 166, 168
AcyI GRCGYC 2 cut(s) 171, 207
AfaI GTAC 1 cut(s) 296
AjiI CACGTC 1 cut(s) 11
AjnI CCWGG 3 cut(s) 81, 111, 230
Alw21I GWGCWC 1 cut(s) 228
Alw26I GTCTC 1 cut(s) 155
Ama87I CYCGRG 1 cut(s) 188
AoxI GGCC 2 cut(s) 114, 145
AspS9I GGNCC 2 cut(s) 64, 115
AsuHPI GGTGA 3 cut(s) 47, 82, 256
AvaI CYCGRG 1 cut(s) 188
AvaII GGWCC 1 cut(s) 64
BbsI GAAGAC 1 cut(s) 245
Bbv12I GWGCWC 1 cut(s) 228
BccI CCATC 1 cut(s) 247
BceAI ACGGC 2 cut(s) 194, 264
BciT130I CCWGG 3 cut(s) 83, 113, 232
BcoDI GTCTC 1 cut(s) 155
BglII AGATCT 1 cut(s) 180
BisI GCNGC 4 cut(s) 109, 127, 145, 169
BlsI GCNGC 4 cut(s) 110, 128, 146, 170
Bme1390I CCNGG 3 cut(s) 83, 113, 232
Bme18I GGWCC 1 cut(s) 64
BmeT110I CYCGRG 1 cut(s) 188
BmgBI CACGTC 1 cut(s) 11
BmgT120I GGNCC 2 cut(s) 64, 115
BmrFI CCNGG 3 cut(s) 83, 113, 232
BmrI ACTGGG 1 cut(s) 41
BmsI GCATC 1 cut(s) 96
BmuI ACTGGG 1 cut(s) 41
BpiI GAAGAC 1 cut(s) 245
BpuEI CTTGAG 2 cut(s) 161, 257
BsaHI GRCGYC 2 cut(s) 171, 207
BsaI GGTCTC 1 cut(s) 155
BsaJI CCNNGG 2 cut(s) 82, 166
Bse118I RCCGGY 1 cut(s) 97
Bse1I ACTGG 1 cut(s) 36
BseBI CCWGG 3 cut(s) 83, 113, 232
BseDI CCNNGG 2 cut(s) 82, 166
BseGI GGATG 1 cut(s) 78
BseNI ACTGG 1 cut(s) 36
BseRI GAGGAG 1 cut(s) 57
Bsh1236I CGCG 2 cut(s) 72, 168
BshFI GGCC 2 cut(s) 116, 147
BsiHKAI GWGCWC 1 cut(s) 228
BsiHKCI CYCGRG 1 cut(s) 188
BsiSI CCGG 1 cut(s) 98
BslFI GGGAC 3 cut(s) 21, 42, 218
BsmAI GTCTC 1 cut(s) 155
BsmFI GGGAC 3 cut(s) 21, 42, 218
BsnI GGCC 2 cut(s) 116, 147
Bso31I GGTCTC 1 cut(s) 155
BsoBI CYCGRG 1 cut(s) 188
Bsp1286I GDGCHC 1 cut(s) 228
Bsp143I GATC 2 cut(s) 150, 180
BspACI CCGC 7 cut(s) 70, 109, 118, 126, 144, 166, 168
BspANI GGCC 2 cut(s) 116, 147
BspFNI CGCG 2 cut(s) 72, 168
BspTNI GGTCTC 1 cut(s) 155
BsrFI RCCGGY 1 cut(s) 97
BsrI ACTGG 1 cut(s) 36
BssAI RCCGGY 1 cut(s) 97
BssECI CCNNGG 2 cut(s) 82, 166
BssMI GATC 2 cut(s) 150, 180
BssNI GRCGYC 2 cut(s) 171, 207
Bst2UI CCWGG 3 cut(s) 83, 113, 232
Bst4CI ACNGT 2 cut(s) 59, 244
Bst6I CTCTTC 1 cut(s) 153
BstACI GRCGYC 2 cut(s) 171, 207
BstC8I GCNNGC 3 cut(s) 99, 118, 228
BstDSI CCRYGG 1 cut(s) 166
BstF5I GGATG 1 cut(s) 78
BstFNI CGCG 2 cut(s) 72, 168
BstKTI GATC 2 cut(s) 153, 183
BstMAI GTCTC 1 cut(s) 155
BstMBI GATC 2 cut(s) 150, 180
BstMWI GCNNNNNNNGC 2 cut(s) 117, 126
BstNI CCWGG 3 cut(s) 83, 113, 232
BstSCI CCNGG 3 cut(s) 81, 111, 230
BstUI CGCG 2 cut(s) 72, 168
BstV2I GAAGAC 1 cut(s) 245
BstX2I RGATCY 1 cut(s) 180
BstYI RGATCY 1 cut(s) 180
BsuRI GGCC 2 cut(s) 116, 147
BtgI CCRYGG 1 cut(s) 166
BtgZI GCGATG 1 cut(s) 266
BtrI CACGTC 1 cut(s) 11
BtsCI GGATG 1 cut(s) 78
Cac8I GCNNGC 3 cut(s) 99, 118, 228
Cfr10I RCCGGY 1 cut(s) 97
Cfr13I GGNCC 2 cut(s) 64, 115
Cfr42I CCGCGG 1 cut(s) 169
CseI GACGC 3 cut(s) 41, 160, 215
Csp6I GTAC 1 cut(s) 295
CviJI RGCY 3 cut(s) 97, 116, 147
CviKI_1 RGCY 3 cut(s) 97, 116, 147
CviQI GTAC 1 cut(s) 295
DpnI GATC 2 cut(s) 152, 182
DpnII GATC 2 cut(s) 150, 180
Eam1104I CTCTTC 1 cut(s) 153
EarI CTCTTC 1 cut(s) 153
Eco31I GGTCTC 1 cut(s) 155
Eco47I GGWCC 1 cut(s) 64
Eco88I CYCGRG 1 cut(s) 188
EcoO109I RGGNCCY 1 cut(s) 64
EcoRII CCWGG 3 cut(s) 81, 111, 230
FaqI GGGAC 3 cut(s) 21, 42, 218
FauI CCCGC 2 cut(s) 125, 173
Fnu4HI GCNGC 4 cut(s) 109, 127, 145, 169
FokI GGATG 1 cut(s) 65
Fsp4HI GCNGC 4 cut(s) 109, 127, 145, 169
GluI GCNGC 4 cut(s) 109, 127, 145, 169
HaeIII GGCC 2 cut(s) 116, 147
HapII CCGG 1 cut(s) 98
HgaI GACGC 3 cut(s) 41, 160, 215
Hin1I GRCGYC 2 cut(s) 171, 207
HinfI GANTC 4 cut(s) 103, 138, 199, 289
HpaII CCGG 1 cut(s) 98
HphI GGTGA 3 cut(s) 47, 82, 256
Hpy166II GTNNAC 1 cut(s) 265
Hpy188III TCNNGA 5 cut(s) 178, 188, 190, 203, 274
Hpy8I GTNNAC 1 cut(s) 265
HpyCH4III ACNGT 2 cut(s) 59, 244
HpyCH4IV ACGT 3 cut(s) 10, 195, 258
HpyF10VI GCNNNNNNNGC 2 cut(s) 117, 126
HpySE526I ACGT 3 cut(s) 10, 195, 258
Hsp92I GRCGYC 2 cut(s) 171, 207
KroI GCCGGC 1 cut(s) 97
KroNI GCCGGC 1 cut(s) 99
KspI CCGCGG 1 cut(s) 169
Kzo9I GATC 2 cut(s) 150, 180
LmnI GCTCC 2 cut(s) 44, 223
LweI GCATC 1 cut(s) 96
MaeII ACGT 3 cut(s) 10, 195, 258
MaeIII GTNAC 3 cut(s) 53, 211, 244
MalI GATC 2 cut(s) 152, 182
MboI GATC 2 cut(s) 150, 180
MboII GAAGA 2 cut(s) 170, 250
MflI RGATCY 1 cut(s) 180
MhlI GDGCHC 1 cut(s) 228
MlyI GAGTC 1 cut(s) 283
MnlI CCTC 7 cut(s) 14, 35, 77, 116, 185, 228, 270
MroNI GCCGGC 1 cut(s) 97
MspA1I CMGCKG 2 cut(s) 144, 168
MspI CCGG 1 cut(s) 98
MspR9I CCNGG 3 cut(s) 83, 113, 232
MvaI CCWGG 3 cut(s) 83, 113, 232
MvnI CGCG 2 cut(s) 72, 168
MwoI GCNNNNNNNGC 2 cut(s) 117, 126
NaeI GCCGGC 1 cut(s) 99
NdeII GATC 2 cut(s) 150, 180
NgoMIV GCCGGC 1 cut(s) 97
NmuCI GTSAC 2 cut(s) 53, 244
PaeR7I CTCGAG 1 cut(s) 188
PcsI WCGNNNNNNNCGW 1 cut(s) 248
PdiI GCCGGC 1 cut(s) 99
PfeI GAWTC 3 cut(s) 103, 138, 199
PkrI GCNGC 4 cut(s) 110, 128, 146, 170
PleI GAGTC 1 cut(s) 283
PpsI GAGTC 1 cut(s) 283
PpuMI RGGWCCY 1 cut(s) 64
Psp5II RGGWCCY 1 cut(s) 64
Psp6I CCWGG 3 cut(s) 81, 111, 230
PspGI CCWGG 3 cut(s) 81, 111, 230
PspPI GGNCC 2 cut(s) 64, 115
PspPPI RGGWCCY 1 cut(s) 64
PsuI RGATCY 1 cut(s) 180
RsaI GTAC 1 cut(s) 296
RsaNI GTAC 1 cut(s) 295
SacII CCGCGG 1 cut(s) 169
SatI GCNGC 4 cut(s) 109, 127, 145, 169
Sau3AI GATC 2 cut(s) 150, 180
Sau96I GGNCC 2 cut(s) 64, 115
SchI GAGTC 1 cut(s) 283
ScrFI CCNGG 3 cut(s) 83, 113, 232
SduI GDGCHC 1 cut(s) 228
SetI ASST 5 cut(s) 13, 66, 198, 218, 261
SfaNI GCATC 1 cut(s) 96
Sfr274I CTCGAG 1 cut(s) 188
Sfr303I CCGCGG 1 cut(s) 169
SgrBI CCGCGG 1 cut(s) 169
SinI GGWCC 1 cut(s) 64
SlaI CTCGAG 1 cut(s) 188
SmlI CTYRAG 3 cut(s) 176, 188, 272
SmoI CTYRAG 3 cut(s) 176, 188, 272
SsiI CCGC 7 cut(s) 70, 109, 118, 126, 144, 166, 168
StyD4I CCNGG 3 cut(s) 81, 111, 230
TaaI ACNGT 2 cut(s) 59, 244
TaiI ACGT 3 cut(s) 13, 198, 261
TaqI TCGA 1 cut(s) 189
TauI GCSGC 4 cut(s) 111, 129, 147, 171
TfiI GAWTC 3 cut(s) 103, 138, 199
TseFI GTSAC 2 cut(s) 53, 244
Tsp45I GTSAC 2 cut(s) 53, 244
TspGWI ACGGA 1 cut(s) 236
VpaK11BI GGWCC 1 cut(s) 64
XhoI CTCGAG 1 cut(s) 188
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.