MD14G1139400.v1.1

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr14
OG0000524
Physical Location & Seq
Forward (+)
23004053 .. 23004364
312 bp
Loading structure...
UTR
Exon/CDS
Intron
MD14G1139400.v1.1.491

Sequence Viewer

Length: 312 bp
ATGACAGGGAGAGGAAAGGGAGGAAAGGGGCTGGGAAAGGGCGGAGCCAAGAGGCACAGGAAGGTATTGAGGGACAACATCCAGGGGATCACCAAGCCTGCCATCCGAAGGCTCGCTCGCAGAGGAGGAGTCAAGCGCATAAGCGGCCTCATCTATGAAGAAACCAGAGGGGTTCTCAAGATCTTCTTGGAGAACGTGATTCGTGATGCTGTGACTTACACCGAGCATGCCAGGAGGAAGACGGTGACTGCCATGGATGTGGTCTATGCTCTCAAGAGGCAGGGTCGAACCCTCTACGGTTTTGGAGGTTAA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
ko05034 ko05203 ko05322 map05034 map05203 map05322
Pfam Domains
Protein Families
CENP-T_C

Protein Analysis

104

Amino Acids

11.42

Weight (kDa)

11.48

Isoelectric Point (pI)

39.98

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
CENP-T_C PF15511 44 - 96 3.4e-08 Centromere kinetochore component CENP-T histone fold
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Orthologous Genes (Group: OG0000524)

Species Orthologous Gene IDs
arabidopsis_thaliana AT1G07660 AT1G07820 AT1G07820 AT2G28740 AT3G45930 AT3G46320 AT3G53730 AT5G59690 AT5G59970 AT5G59970
malus_domestica MD03G1097000.v1.1 MD03G1105400.v1.1 MD04G1124800.v1.1 MD06G1122500.v1.1 MD07G1184400.v1.1 MD07G1194500.v1.1 MD11G1143500.v1.1 MD12G1139800.v1.1 MD14G1139400.v1.1 MD15G1139200.v1.1
rosa_chinensis RchiOBHm_Chr1g0364991 RchiOBHm_Chr3g0467051 RchiOBHm_Chr5g0062221 RchiOBHm_Chr5g0063251 RchiOBHm_Chr5g0063281 RchiOBHm_Chr5g0063731 RchiOBHm_Chr7g0187711
rosa_laevigata RLG00000024533
rosa_multiflora Rmu_sc0004483.1_g000025 Rmu_sc0005045.1_g000017 Rmu_sc0005045.1_g000024 Rmu_sc0005638.1_g000003 Rmu_sc0042820.1_g000002 Rmu_sc0042820.1_g000003 Rmu_ssc0000112.1_g000021 Rmu_ssc0000309.1_g000047 Rmu_ssc0000409.1_g000022
rosa_roxburghii Rroxscaffold_1G00017140 Rroxscaffold_1G00017150 Rroxscaffold_1G00017430 Rroxscaffold_1G00017460 Rroxscaffold_4G00292020 Rroxscaffold_6G00413990
rosa_rugosa Rorug01G0318800 Rorug01G0329200 Rorug03G0085000 Rorug05G0347300 Rorug05G0355600 Rorug05G0355800 Rorug05G0358800 Rorug05G0358800 Rorug05G0358900 Rorug06G0483800
rosa_samantha Rh1AG327700 Rh1BG289000 Rh1CG305700 Rh1DG320500 Rh3AG133000 Rh3BG154000 Rh3CG154000 Rh3DG155100 Rh5AG407800 Rh5AG417800 Rh5BG421500 Rh5BG430300 Rh5BG433000 Rh5BG433200 Rh5CG445700 Rh5CG456200 Rh5CG456400 Rh5DG436500 Rh5DG443700 Rh5DG443900 Rh5DG446400 Rh5DG446600 Rh7BG090600 Rh7CG089600 Rh7DG091100
rosa_wichuraiana Rw1G029050 Rw3G012590 Rw5G038430 Rw5G039030 Rw5G039230 Rw5G039250 Rw7G007670

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AciI CCGC 2 cut(s) 42, 144
AclWI GGATC 1 cut(s) 95
AfiI CCNNNNNNNGG 1 cut(s) 108
AjnI CCWGG 2 cut(s) 81, 230
AlwI GGATC 1 cut(s) 95
AoxI GGCC 1 cut(s) 145
AspLEI GCGC 1 cut(s) 138
AsuHPI GGTGA 2 cut(s) 82, 256
BbsI GAAGAC 1 cut(s) 245
BccI CCATC 1 cut(s) 110
BciT130I CCWGG 2 cut(s) 83, 232
BglII AGATCT 1 cut(s) 180
BisI GCNGC 1 cut(s) 145
BlsI GCNGC 1 cut(s) 146
Bme1390I CCNGG 2 cut(s) 83, 232
BmiI GGNNCC 1 cut(s) 46
BmrFI CCNGG 2 cut(s) 83, 232
BmsI GCATC 1 cut(s) 196
BpiI GAAGAC 1 cut(s) 245
BplI GAGNNNNNCTC 2 cut(s) 159, 191
BpuEI CTTGAG 2 cut(s) 161, 257
BsaJI CCNNGG 2 cut(s) 82, 252
Bsc4I CCNNNNNNNGG 1 cut(s) 108
BseBI CCWGG 2 cut(s) 83, 232
BseDI CCNNGG 2 cut(s) 82, 252
BseGI GGATG 3 cut(s) 78, 102, 262
BseLI CCNNNNNNNGG 1 cut(s) 108
BseRI GAGGAG 2 cut(s) 138, 141
BseYI CCCAGC 1 cut(s) 31
BshFI GGCC 1 cut(s) 147
BslFI GGGAC 1 cut(s) 86
BslI CCNNNNNNNGG 1 cut(s) 108
BsmFI GGGAC 1 cut(s) 86
BsnI GGCC 1 cut(s) 147
Bsp143I GATC 2 cut(s) 87, 180
Bsp19I CCATGG 1 cut(s) 252
BspACI CCGC 2 cut(s) 42, 144
BspANI GGCC 1 cut(s) 147
BspLI GGNNCC 1 cut(s) 46
BspPI GGATC 1 cut(s) 95
BssECI CCNNGG 2 cut(s) 82, 252
BssMI GATC 2 cut(s) 87, 180
BssT1I CCWWGG 1 cut(s) 252
Bst2UI CCWGG 2 cut(s) 83, 232
Bst4CI ACNGT 2 cut(s) 244, 299
BstC8I GCNNGC 4 cut(s) 99, 114, 118, 228
BstDSI CCRYGG 1 cut(s) 252
BstF5I GGATG 3 cut(s) 78, 102, 262
BstHHI GCGC 1 cut(s) 138
BstKTI GATC 2 cut(s) 90, 183
BstMBI GATC 2 cut(s) 87, 180
BstMWI GCNNNNNNNGC 1 cut(s) 144
BstNI CCWGG 2 cut(s) 83, 232
BstNSI RCATGY 1 cut(s) 230
BstSCI CCNGG 2 cut(s) 81, 230
BstV2I GAAGAC 1 cut(s) 245
BstX2I RGATCY 1 cut(s) 180
BstXI CCANNNNNNTGG 1 cut(s) 259
BstYI RGATCY 1 cut(s) 180
BsuRI GGCC 1 cut(s) 147
BtgI CCRYGG 1 cut(s) 252
BtsCI GGATG 3 cut(s) 78, 102, 262
Cac8I GCNNGC 4 cut(s) 99, 114, 118, 228
CfoI GCGC 1 cut(s) 138
CviAII CATG 2 cut(s) 227, 253
CviJI RGCY 5 cut(s) 31, 47, 97, 112, 147
CviKI_1 RGCY 5 cut(s) 31, 47, 97, 112, 147
DpnI GATC 2 cut(s) 89, 182
DpnII GATC 2 cut(s) 87, 180
EciI GGCGGA 1 cut(s) 57
Eco130I CCWWGG 1 cut(s) 252
EcoRII CCWGG 2 cut(s) 81, 230
EcoT14I CCWWGG 1 cut(s) 252
ErhI CCWWGG 1 cut(s) 252
FaeI CATG 2 cut(s) 230, 256
FaiI YATR 5 cut(s) 140, 156, 228, 254, 267
FalI AAGNNNNNCTT 2 cut(s) 170, 202
FaqI GGGAC 1 cut(s) 86
FatI CATG 2 cut(s) 226, 252
Fnu4HI GCNGC 1 cut(s) 145
FokI GGATG 3 cut(s) 65, 89, 269
Fsp4HI GCNGC 1 cut(s) 145
GlaI GCGC 1 cut(s) 137
GluI GCNGC 1 cut(s) 145
GsaI CCCAGC 1 cut(s) 35
HaeIII GGCC 1 cut(s) 147
HhaI GCGC 1 cut(s) 138
Hin1II CATG 2 cut(s) 230, 256
Hin6I GCGC 1 cut(s) 136
HinP1I GCGC 1 cut(s) 136
HinfI GANTC 2 cut(s) 129, 199
HphI GGTGA 2 cut(s) 82, 256
Hpy188I TCNGA 1 cut(s) 107
Hpy188III TCNNGA 3 cut(s) 178, 203, 274
HpyAV CCTTC 2 cut(s) 55, 102
HpyCH4III ACNGT 2 cut(s) 244, 299
HpyCH4IV ACGT 1 cut(s) 195
HpyF10VI GCNNNNNNNGC 1 cut(s) 144
HpySE526I ACGT 1 cut(s) 195
Hsp92II CATG 2 cut(s) 230, 256
HspAI GCGC 1 cut(s) 136
Kzo9I GATC 2 cut(s) 87, 180
LmnI GCTCC 1 cut(s) 44
LpnPI CCDG 9 cut(s) 17, 43, 68, 95, 111, 178, 217, 244, 266
LweI GCATC 1 cut(s) 196
MaeII ACGT 1 cut(s) 195
MaeIII GTNAC 2 cut(s) 211, 244
MalI GATC 2 cut(s) 89, 182
MboI GATC 2 cut(s) 87, 180
MboII GAAGA 3 cut(s) 170, 175, 250
MflI RGATCY 1 cut(s) 180
MlyI GAGTC 1 cut(s) 138
MseI TTAA 1 cut(s) 310
MslI CAYNNNNRTG 1 cut(s) 257
MspR9I CCNGG 2 cut(s) 83, 232
MvaI CCWGG 2 cut(s) 83, 232
MwoI GCNNNNNNNGC 1 cut(s) 144
NcoI CCATGG 1 cut(s) 252
NdeII GATC 2 cut(s) 87, 180
NlaIII CATG 2 cut(s) 230, 256
NlaIV GGNNCC 1 cut(s) 46
NmuCI GTSAC 2 cut(s) 211, 244
NspI RCATGY 1 cut(s) 230
PaeI GCATGC 1 cut(s) 230
PfeI GAWTC 1 cut(s) 199
PkrI GCNGC 1 cut(s) 146
PleI GAGTC 1 cut(s) 137
PpsI GAGTC 1 cut(s) 137
Psp6I CCWGG 2 cut(s) 81, 230
PspFI CCCAGC 1 cut(s) 31
PspGI CCWGG 2 cut(s) 81, 230
PspN4I GGNNCC 1 cut(s) 46
PsuI RGATCY 1 cut(s) 180
RseI CAYNNNNRTG 1 cut(s) 257
SaqAI TTAA 1 cut(s) 310
SatI GCNGC 1 cut(s) 145
Sau3AI GATC 2 cut(s) 87, 180
SchI GAGTC 1 cut(s) 138
ScrFI CCNGG 2 cut(s) 83, 232
SetI ASST 3 cut(s) 66, 198, 310
SfaNI GCATC 1 cut(s) 196
SmiMI CAYNNNNRTG 1 cut(s) 257
SmlI CTYRAG 2 cut(s) 176, 272
SmoI CTYRAG 2 cut(s) 176, 272
SphI GCATGC 1 cut(s) 230
SsiI CCGC 2 cut(s) 42, 144
StyD4I CCNGG 2 cut(s) 81, 230
StyI CCWWGG 1 cut(s) 252
TaaI ACNGT 2 cut(s) 244, 299
TaiI ACGT 1 cut(s) 198
TaqI TCGA 1 cut(s) 286
TauI GCSGC 1 cut(s) 147
TfiI GAWTC 1 cut(s) 199
Tru1I TTAA 1 cut(s) 310
Tru9I TTAA 1 cut(s) 310
TseFI GTSAC 2 cut(s) 211, 244
Tsp45I GTSAC 2 cut(s) 211, 244
TspDTI ATGAA 1 cut(s) 171
XceI RCATGY 1 cut(s) 230
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.