MD07G1184400.v1.1

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr07
OG0000524
Physical Location & Seq
Forward (+)
26545176 .. 26546473
1298 bp
Loading structure...
UTR
Exon/CDS
Intron
MD07G1184400.v1.1.491

Sequence Viewer

Length: 312 bp
ATGACTGGGCGTGGAAAGGGAGGAAAAGGTCTGGGAAAGGGAGGAGCAAAACGTCACCGTAAGGTCCTCCGCGACAACATCCAGGGGATCACAAAGCCGGCCATCCGCCGTTTGGCTCGCAGGGGCGGCGTGAAGCGTATCAGCGGTCTGATCTACGAGGAGACACGTGGAGTGCTCAAGATCTTTTTGGAGAACGTCATCAGAGACGCCGTGACCTACACCGAGCACGCTCGCCGCAAGACCGTGACGGCCATGGATGTGGTCTACGCGCTCAAAAGGCAGGGCAGGACCCTGTACGGGTTCGGTGGCTAG
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
ko05034 ko05203 ko05322 map05034 map05203 map05322
Pfam Domains
Protein Families
CENP-T_C

Protein Analysis

104

Amino Acids

11.42

Weight (kDa)

11.48

Isoelectric Point (pI)

39.98

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
CENP-T_C PF15511 44 - 96 3.4e-08 Centromere kinetochore component CENP-T histone fold
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
iTOL Interactive Tree Of Life · Most popular EvolView Flexible annotations MEGA Desktop phylogenetics suite FigTree Desktop tree editor

Orthologous Genes (Group: OG0000524)

Species Orthologous Gene IDs
arabidopsis_thaliana AT1G07660 AT1G07820 AT1G07820 AT2G28740 AT3G45930 AT3G46320 AT3G53730 AT5G59690 AT5G59970 AT5G59970
malus_domestica MD03G1097000.v1.1 MD03G1105400.v1.1 MD04G1124800.v1.1 MD06G1122500.v1.1 MD07G1184400.v1.1 MD07G1194500.v1.1 MD11G1143500.v1.1 MD12G1139800.v1.1 MD14G1139400.v1.1 MD15G1139200.v1.1
rosa_chinensis RchiOBHm_Chr1g0364991 RchiOBHm_Chr3g0467051 RchiOBHm_Chr5g0062221 RchiOBHm_Chr5g0063251 RchiOBHm_Chr5g0063281 RchiOBHm_Chr5g0063731 RchiOBHm_Chr7g0187711
rosa_laevigata RLG00000024533
rosa_multiflora Rmu_sc0004483.1_g000025 Rmu_sc0005045.1_g000017 Rmu_sc0005045.1_g000024 Rmu_sc0005638.1_g000003 Rmu_sc0042820.1_g000002 Rmu_sc0042820.1_g000003 Rmu_ssc0000112.1_g000021 Rmu_ssc0000309.1_g000047 Rmu_ssc0000409.1_g000022
rosa_roxburghii Rroxscaffold_1G00017140 Rroxscaffold_1G00017150 Rroxscaffold_1G00017430 Rroxscaffold_1G00017460 Rroxscaffold_4G00292020 Rroxscaffold_6G00413990
rosa_rugosa Rorug01G0318800 Rorug01G0329200 Rorug03G0085000 Rorug05G0347300 Rorug05G0355600 Rorug05G0355800 Rorug05G0358800 Rorug05G0358800 Rorug05G0358900 Rorug06G0483800
rosa_samantha Rh1AG327700 Rh1BG289000 Rh1CG305700 Rh1DG320500 Rh3AG133000 Rh3BG154000 Rh3CG154000 Rh3DG155100 Rh5AG407800 Rh5AG417800 Rh5BG421500 Rh5BG430300 Rh5BG433000 Rh5BG433200 Rh5CG445700 Rh5CG456200 Rh5CG456400 Rh5DG436500 Rh5DG443700 Rh5DG443900 Rh5DG446400 Rh5DG446600 Rh7BG090600 Rh7CG089600 Rh7DG091100
rosa_wichuraiana Rw1G029050 Rw3G012590 Rw5G038430 Rw5G039030 Rw5G039230 Rw5G039250 Rw7G007670

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccI GTMKAC 1 cut(s) 264
AccII CGCG 2 cut(s) 72, 269
AciI CCGC 5 cut(s) 70, 106, 126, 144, 235
AclWI GGATC 1 cut(s) 95
AcoI YGGCCR 2 cut(s) 99, 249
AcvI CACGTG 1 cut(s) 167
AcyI GRCGYC 1 cut(s) 207
AfaI GTAC 1 cut(s) 296
AfiI CCNNNNNNNGG 2 cut(s) 112, 297
AflIII ACRYGT 1 cut(s) 164
AjnI CCWGG 1 cut(s) 81
Alw21I GWGCWC 2 cut(s) 177, 228
Alw26I GTCTC 2 cut(s) 155, 198
AlwI GGATC 1 cut(s) 95
AoxI GGCC 2 cut(s) 99, 249
AspLEI GCGC 1 cut(s) 271
AspS9I GGNCC 2 cut(s) 64, 288
AsuHPI GGTGA 1 cut(s) 47
AvaII GGWCC 2 cut(s) 64, 288
BbrPI CACGTG 1 cut(s) 167
Bbv12I GWGCWC 2 cut(s) 177, 228
BccI CCATC 1 cut(s) 110
BceAI ACGGC 3 cut(s) 93, 194, 264
BciT130I CCWGG 1 cut(s) 83
BcoDI GTCTC 2 cut(s) 155, 198
BfaI CTAG 1 cut(s) 310
BglII AGATCT 1 cut(s) 180
BisI GCNGC 2 cut(s) 127, 235
BlsI GCNGC 2 cut(s) 128, 236
Bme1390I CCNGG 1 cut(s) 83
Bme18I GGWCC 2 cut(s) 64, 288
BmgT120I GGNCC 2 cut(s) 64, 288
BmiI GGNNCC 1 cut(s) 290
BmrFI CCNGG 1 cut(s) 83
BmrI ACTGGG 1 cut(s) 15
BmuI ACTGGG 1 cut(s) 15
BpuEI CTTGAG 1 cut(s) 161
BsaAI YACGTR 1 cut(s) 167
BsaHI GRCGYC 1 cut(s) 207
BsaJI CCNNGG 2 cut(s) 82, 252
Bsc4I CCNNNNNNNGG 2 cut(s) 112, 297
Bse118I RCCGGY 1 cut(s) 97
Bse1I ACTGG 1 cut(s) 10
BseBI CCWGG 1 cut(s) 83
BseDI CCNNGG 2 cut(s) 82, 252
BseGI GGATG 3 cut(s) 78, 102, 262
BseLI CCNNNNNNNGG 2 cut(s) 112, 297
BseNI ACTGG 1 cut(s) 10
BseRI GAGGAG 2 cut(s) 57, 173
Bsh1236I CGCG 2 cut(s) 72, 269
BshFI GGCC 2 cut(s) 101, 251
BsiHKAI GWGCWC 2 cut(s) 177, 228
BsiSI CCGG 1 cut(s) 98
BslI CCNNNNNNNGG 2 cut(s) 112, 297
BsmAI GTCTC 2 cut(s) 155, 198
BsmBI CGTCTC 1 cut(s) 198
BsnI GGCC 2 cut(s) 101, 251
Bsp1286I GDGCHC 2 cut(s) 177, 228
Bsp143I GATC 3 cut(s) 87, 150, 180
Bsp19I CCATGG 1 cut(s) 252
BspACI CCGC 5 cut(s) 70, 106, 126, 144, 235
BspANI GGCC 2 cut(s) 101, 251
BspFNI CGCG 2 cut(s) 72, 269
BspLI GGNNCC 1 cut(s) 290
BspPI GGATC 1 cut(s) 95
BsrFI RCCGGY 1 cut(s) 97
BsrI ACTGG 1 cut(s) 10
BssAI RCCGGY 1 cut(s) 97
BssECI CCNNGG 2 cut(s) 82, 252
BssMI GATC 3 cut(s) 87, 150, 180
BssNI GRCGYC 1 cut(s) 207
BssT1I CCWWGG 1 cut(s) 252
Bst2UI CCWGG 1 cut(s) 83
Bst4CI ACNGT 2 cut(s) 59, 244
BstACI GRCGYC 1 cut(s) 207
BstBAI YACGTR 1 cut(s) 167
BstC8I GCNNGC 4 cut(s) 99, 118, 228, 232
BstDSI CCRYGG 1 cut(s) 252
BstF5I GGATG 3 cut(s) 78, 102, 262
BstFNI CGCG 2 cut(s) 72, 269
BstHHI GCGC 1 cut(s) 271
BstKTI GATC 3 cut(s) 90, 153, 183
BstMAI GTCTC 2 cut(s) 155, 198
BstMBI GATC 3 cut(s) 87, 150, 180
BstMWI GCNNNNNNNGC 2 cut(s) 126, 277
BstNI CCWGG 1 cut(s) 83
BstSCI CCNGG 1 cut(s) 81
BstUI CGCG 2 cut(s) 72, 269
BstX2I RGATCY 1 cut(s) 180
BstXI CCANNNNNNTGG 1 cut(s) 259
BstYI RGATCY 1 cut(s) 180
BsuRI GGCC 2 cut(s) 101, 251
BtgI CCRYGG 1 cut(s) 252
BtsCI GGATG 3 cut(s) 78, 102, 262
Cac8I GCNNGC 4 cut(s) 99, 118, 228, 232
CfoI GCGC 1 cut(s) 271
Cfr10I RCCGGY 1 cut(s) 97
Cfr13I GGNCC 2 cut(s) 64, 288
CseI GACGC 1 cut(s) 215
Csp6I GTAC 1 cut(s) 295
CviAII CATG 1 cut(s) 253
CviJI RGCY 5 cut(s) 97, 101, 116, 251, 309
CviKI_1 RGCY 5 cut(s) 97, 101, 116, 251, 309
CviQI GTAC 1 cut(s) 295
DpnI GATC 3 cut(s) 89, 152, 182
DpnII GATC 3 cut(s) 87, 150, 180
EaeI YGGCCR 2 cut(s) 99, 249
EciI GGCGGA 1 cut(s) 95
Eco130I CCWWGG 1 cut(s) 252
Eco47I GGWCC 2 cut(s) 64, 288
Eco72I CACGTG 1 cut(s) 167
EcoO109I RGGNCCY 2 cut(s) 64, 288
EcoRII CCWGG 1 cut(s) 81
EcoT14I CCWWGG 1 cut(s) 252
ErhI CCWWGG 1 cut(s) 252
Esp3I CGTCTC 1 cut(s) 198
FaeI CATG 1 cut(s) 256
FaiI YATR 1 cut(s) 254
FatI CATG 1 cut(s) 252
FblI GTMKAC 1 cut(s) 264
Fnu4HI GCNGC 2 cut(s) 127, 235
FokI GGATG 3 cut(s) 65, 89, 269
Fsp4HI GCNGC 2 cut(s) 127, 235
FspBI CTAG 1 cut(s) 310
GlaI GCGC 1 cut(s) 270
GluI GCNGC 2 cut(s) 127, 235
HaeIII GGCC 2 cut(s) 101, 251
HapII CCGG 1 cut(s) 98
HgaI GACGC 1 cut(s) 215
HhaI GCGC 1 cut(s) 271
Hin1I GRCGYC 1 cut(s) 207
Hin1II CATG 1 cut(s) 256
Hin6I GCGC 1 cut(s) 269
HinP1I GCGC 1 cut(s) 269
HpaII CCGG 1 cut(s) 98
HphI GGTGA 1 cut(s) 47
Hpy166II GTNNAC 1 cut(s) 265
Hpy188I TCNGA 2 cut(s) 150, 203
Hpy188III TCNNGA 1 cut(s) 178
Hpy8I GTNNAC 1 cut(s) 265
HpyCH4III ACNGT 2 cut(s) 59, 244
HpyCH4IV ACGT 3 cut(s) 52, 166, 195
HpyF10VI GCNNNNNNNGC 2 cut(s) 126, 277
HpySE526I ACGT 3 cut(s) 52, 166, 195
Hsp92I GRCGYC 1 cut(s) 207
Hsp92II CATG 1 cut(s) 256
HspAI GCGC 1 cut(s) 269
KroI GCCGGC 1 cut(s) 97
KroNI GCCGGC 1 cut(s) 99
Kzo9I GATC 3 cut(s) 87, 150, 180
LmnI GCTCC 1 cut(s) 44
LpnPI CCDG 8 cut(s) 17, 68, 95, 106, 111, 266, 271, 305
MaeI CTAG 1 cut(s) 310
MaeII ACGT 3 cut(s) 52, 166, 195
MaeIII GTNAC 3 cut(s) 53, 211, 244
MalI GATC 3 cut(s) 89, 152, 182
MboI GATC 3 cut(s) 87, 150, 180
MflI RGATCY 1 cut(s) 180
MhlI GDGCHC 2 cut(s) 177, 228
MnlI CCTC 4 cut(s) 14, 35, 77, 151
MroNI GCCGGC 1 cut(s) 97
MslI CAYNNNNRTG 1 cut(s) 257
MspA1I CMGCKG 1 cut(s) 144
MspI CCGG 1 cut(s) 98
MspR9I CCNGG 1 cut(s) 83
MvaI CCWGG 1 cut(s) 83
MvnI CGCG 2 cut(s) 72, 269
MwoI GCNNNNNNNGC 2 cut(s) 126, 277
NaeI GCCGGC 1 cut(s) 99
NcoI CCATGG 1 cut(s) 252
NdeII GATC 3 cut(s) 87, 150, 180
NgoMIV GCCGGC 1 cut(s) 97
NlaIII CATG 1 cut(s) 256
NlaIV GGNNCC 1 cut(s) 290
NmuCI GTSAC 3 cut(s) 53, 211, 244
PdiI GCCGGC 1 cut(s) 99
PkrI GCNGC 2 cut(s) 128, 236
PmaCI CACGTG 1 cut(s) 167
PmlI CACGTG 1 cut(s) 167
Ppu21I YACGTR 1 cut(s) 167
PpuMI RGGWCCY 2 cut(s) 64, 288
Psp5II RGGWCCY 2 cut(s) 64, 288
Psp6I CCWGG 1 cut(s) 81
PspCI CACGTG 1 cut(s) 167
PspGI CCWGG 1 cut(s) 81
PspN4I GGNNCC 1 cut(s) 290
PspPI GGNCC 2 cut(s) 64, 288
PspPPI RGGWCCY 2 cut(s) 64, 288
PsuI RGATCY 1 cut(s) 180
RsaI GTAC 1 cut(s) 296
RsaNI GTAC 1 cut(s) 295
RseI CAYNNNNRTG 1 cut(s) 257
SatI GCNGC 2 cut(s) 127, 235
Sau3AI GATC 3 cut(s) 87, 150, 180
Sau96I GGNCC 2 cut(s) 64, 288
ScrFI CCNGG 1 cut(s) 83
SduI GDGCHC 2 cut(s) 177, 228
SetI ASST 6 cut(s) 31, 55, 66, 169, 198, 218
SinI GGWCC 2 cut(s) 64, 288
SmiMI CAYNNNNRTG 1 cut(s) 257
SmlI CTYRAG 1 cut(s) 176
SmoI CTYRAG 1 cut(s) 176
SsiI CCGC 5 cut(s) 70, 106, 126, 144, 235
SspMI CTAG 1 cut(s) 310
StyD4I CCNGG 1 cut(s) 81
StyI CCWWGG 1 cut(s) 252
TaaI ACNGT 2 cut(s) 59, 244
TaiI ACGT 3 cut(s) 55, 169, 198
TauI GCSGC 2 cut(s) 129, 237
TseFI GTSAC 3 cut(s) 53, 211, 244
Tsp45I GTSAC 3 cut(s) 53, 211, 244
VpaK11BI GGWCC 2 cut(s) 64, 288
XcmI CCANNNNNNNNNTGG 1 cut(s) 109
XmiI GTMKAC 1 cut(s) 264
XspI CTAG 1 cut(s) 310
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.