Basic Information

Type: gene

Biological Identity

Species

pyrus_communis

Chromosome

Chr6

Orthogroup ID

OG0005386

Physical Location & Seq

Genomic Coordinates Forward (+)

16014252 .. 16016631

Gene Structure 2380 bp

Loading structure...

UTR

Exon/CDS

Intron

Transcript / Protein ID

pycom06g10740.2

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1254 bp

ATGGCGGAATCCATCATTACCTCAGAAAAACCCTCCACCTCGTCCCCTCTAGAGCCTCCTTCCCGTATCGTCTGCCACGTCTGCCAGAAGCAATTTTCTCAGTACACATGCCCTCGATGCAACTCACGTTACTGTTCCCTGCACTGCTACAAGTCGCATAATCTCCGGTGTACCGAATCGTTTATGCGGGAGAATGTGGTGGGGGAGATGGGGCAATTGGGGCCCGATGACGAAACTAAACAGAAAATGCTGGACATACTGAAACGATTTCACTCTGAAGAAGAAGAAACTGATGACATGGATGATGATGATGATGATAATGCTGCAGGTTCTGCACTGTCTGAGGAGACTATTCAAAAAGTGCTGTCTGGTGGTGAAGTTAGTCTGGATGATCTATCTACAGAAGAGAAGAAACTATTCCAAAGAGCTGTCGTTTCTGGGGAACTTAGCAAGATGATTAAGCCTTGGGATCCGTGGTGGTTGAAGCCTTCTGCCAGAACAATATCATTTAGCAAGGAAGGATCCCAACTTATCCAACCTCTTGTCAAAGACGATGAATCAATGTCACCTGAGGATAATTCAGAGAGCAATCAAGCGAGTGAGATTCCACCCGGGCCTGACACCCCACTGCCACCAGTCAGCAAGCTGAGTTCCACAAAGCCATCACCGTCCTTAGCTGTTCATCTGGTGGACATCATATACAGCTACTGTTTCACACTCCGTTTCTACAATGGAGATTGGAAATCGGATGCCATAGGATCATCCATGGCGGTGCTTTCTGTCTCCAATGTACTGGGCCAGGGTGGGCAACCGGAGACTGTCCTGGAAGTGCTGTCTTATTGCTTGGAAAAGACCTGCTCCCCAGACTTCAAACATACAGGCGGCTTGCAATTTGGACTCGGTCTCATAGATGATGTAACAAGCCTATTAACGCTAGGAACACCTGCTTTGTTGTGCTTGCTCTGTGATCTGCAGAGGATGGTTCAGGCTGGGGAGAGGGATCTGAAGTCGGAGAAACCACGGAAGTCGTCACGAAGAACAGAAATTAGGAACAAGCTGAAGTTGGCCGAACGGAAAATTTATTTCATCATGTGTTGGGTGCACGAGCAAACCGGGGAAGTTTGGACTTCCTTAGCAGCCATTGTAACGGCCGAAAAGAGTTCAGCTCTGAGTTATCAATCGGCTTCGAGGCCCGGGAAAGCGGAGAAGAAAGCCGAACCAAAGAGCAAGGTTTTGATTCAGGAGATTAGATGA

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

No ontology terms assigned.

KEGG Pathways

Metabolic & Signaling

No pathways identified.

Pfam Domains

Protein Families

SHQ1 zf-HIT

Protein Analysis

418

Amino Acids

46.36

Weight (kDa)

5.27

Isoelectric Point (pI)

46.96

Instability Index

Protein Domains (Pfam)

No Pfam domains detected for this protein.

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

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Orthologous Genes (Group: OG0005386)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT5G63830
fragaria_vesca	FvH4_4g16080 FvH4_4g16080 FvH4_4g16080 FvH4_4g16080
malus_domestica	MD06G1114600.v1.1
prunus_persica	Prupe.5G127300_v2.0.a1
pyrus_communis	pycom06g10740
rosa_chinensis	RchiOBHm_Chr7g0184121 RchiOBHm_Chr7g0186571
rosa_laevigata	RLG00000004831
rosa_multiflora	Rmu_sc0000645.1_g000018 Rmu_sc0004712.1_g000003 Rmu_sc0025350.1_g000008
rosa_roxburghii	Rroxscaffold_3G00268020 Rroxscaffold_3G00269860
rosa_rugosa	Rorug06G0463200 Rorug06G0475200
rosa_samantha	Rh7AG065800 Rh7AG082600 Rh7BG064400 Rh7BG081700 Rh7CG065000 Rh7CG082000 Rh7DG064600 Rh7DG083000
rosa_wichuraiana	Rw7G005300 Rw7G006900 Rw7G007120

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AarI	CACCTGC	1 cut(s)	952
Acc36I	ACCTGC	3 cut(s)	317, 863, 952
AciI	CCGC	5 cut(s)	5, 187, 770, 882, 1202
AclWI	GGATC	6 cut(s)	464, 477, 516, 529, 766, 1008
AcoI	YGGCCR	2 cut(s)	1065, 1149
AcsI	RAATTY	1 cut(s)	1077
AcuI	CTGAAG	3 cut(s)	297, 1025, 1079
AfaI	GTAC	3 cut(s)	104, 172, 792
AgsI	TTSAA	3 cut(s)	356, 484, 871
AjiI	CACGTC	1 cut(s)	79
AjnI	CCWGG	2 cut(s)	798, 822
AluBI	AGCT	6 cut(s)	428, 646, 677, 705, 1057, 1166
AluI	AGCT	6 cut(s)	428, 646, 677, 705, 1057, 1166
Alw21I	GWGCWC	1 cut(s)	1104
Alw26I	GTCTC	4 cut(s)	341, 787, 809, 908
Alw44I	GTGCAC	1 cut(s)	1100
AlwI	GGATC	6 cut(s)	464, 477, 516, 529, 766, 1008
AlwNI	CAGNNNCTG	2 cut(s)	332, 708
Ama87I	CYCGRG	2 cut(s)	611, 1193
AoxI	GGCC	6 cut(s)	221, 614, 796, 1065, 1149, 1190
ApaI	GGGCCC	1 cut(s)	225
ApaLI	GTGCAC	1 cut(s)	1100
ApeKI	GCWGC	2 cut(s)	323, 1136
ApoI	RAATTY	1 cut(s)	1077
Asp700I	GAANNNNTTC	1 cut(s)	416
AspS9I	GGNCC	5 cut(s)	221, 222, 614, 796, 1191
AsuC2I	CCSGG	5 cut(s)	612, 613, 1114, 1194, 1195
AsuHPI	GGTGA	3 cut(s)	386, 558, 657
AvaI	CYCGRG	2 cut(s)	611, 1193
AxyI	CCTNAGG	1 cut(s)	570
BaeGI	GKGCMC	2 cut(s)	225, 1104
BamHI	GGATCC	2 cut(s)	469, 521
BanII	GRGCYC	1 cut(s)	225
BauI	CACGAG	1 cut(s)	1103
Bbv12I	GWGCWC	1 cut(s)	1104
BbvI	GCAGC	2 cut(s)	310, 1148
BccI	CCATC	4 cut(s)	20, 202, 670, 973
BceAI	ACGGC	1 cut(s)	1164
BciT130I	CCWGG	2 cut(s)	800, 824
BcnI	CCSGG	5 cut(s)	612, 613, 1114, 1194, 1195
BcoDI	GTCTC	4 cut(s)	341, 787, 809, 908
BfaI	CTAG	2 cut(s)	50, 935
BfmI	CTRYAG	3 cut(s)	324, 399, 971
BfuAI	ACCTGC	3 cut(s)	317, 863, 952
BisI	GCNGC	3 cut(s)	324, 883, 1137
BlsI	GCNGC	3 cut(s)	325, 884, 1138
Bme1390I	CCNGG	7 cut(s)	612, 613, 800, 824, 1114, 1194, 1195
BmeT110I	CYCGRG	2 cut(s)	611, 1193
BmgBI	CACGTC	1 cut(s)	79
BmgT120I	GGNCC	5 cut(s)	221, 222, 614, 796, 1191
BmiI	GGNNCC	4 cut(s)	222, 223, 471, 523
BmrFI	CCNGG	7 cut(s)	612, 613, 800, 824, 1114, 1194, 1195
BmrI	ACTGGG	1 cut(s)	803
BmsI	GCATC	2 cut(s)	107, 739
BmuI	ACTGGG	1 cut(s)	803
BplI	GAGNNNNNCTC	2 cut(s)	1150, 1182
Bpu10I	CCTNAGC	2 cut(s)	673, 1132
BpuMI	CCSGG	5 cut(s)	612, 613, 1114, 1194, 1195
BsaI	GGTCTC	1 cut(s)	908
BsaJI	CCNNGG	8 cut(s)	464, 473, 611, 765, 799, 1019, 1113, 1193
BsaWI	WCCGGW	2 cut(s)	165, 811
Bse1I	ACTGG	2 cut(s)	635, 798
Bse21I	CCTNAGG	1 cut(s)	570
BseBI	CCWGG	2 cut(s)	800, 824
BseDI	CCNNGG	8 cut(s)	464, 473, 611, 765, 799, 1019, 1113, 1193
BseGI	GGATG	5 cut(s)	307, 394, 754, 761, 984
BseMII	CTCAG	6 cut(s)	36, 113, 333, 561, 638, 1160
BseNI	ACTGG	2 cut(s)	635, 798
BseRI	GAGGAG	1 cut(s)	359
BseSI	GKGCMC	2 cut(s)	225, 1104
BseX3I	CGGCCG	1 cut(s)	1149
BseXI	GCAGC	2 cut(s)	310, 1148
BseYI	CCCAGC	1 cut(s)	989
BsgI	GTGCAG	2 cut(s)	125, 318
Bsh1285I	CGRYCG	1 cut(s)	1152
BshFI	GGCC	6 cut(s)	223, 616, 798, 1067, 1151, 1192
BsiEI	CGRYCG	1 cut(s)	1152
BsiHKAI	GWGCWC	1 cut(s)	1104
BsiHKCI	CYCGRG	2 cut(s)	611, 1193
BsiSI	CCGG	5 cut(s)	166, 612, 812, 1113, 1194
BslFI	GGGAC	1 cut(s)	28
BsmAI	GTCTC	4 cut(s)	341, 787, 809, 908
BsmFI	GGGAC	1 cut(s)	28
BsnI	GGCC	6 cut(s)	223, 616, 798, 1067, 1151, 1192
Bso31I	GGTCTC	1 cut(s)	908
BsoBI	CYCGRG	2 cut(s)	611, 1193
Bsp120I	GGGCCC	1 cut(s)	221
Bsp1286I	GDGCHC	2 cut(s)	225, 1104
Bsp143I	GATC	6 cut(s)	391, 469, 521, 758, 967, 1000
Bsp19I	CCATGG	1 cut(s)	765
BspACI	CCGC	5 cut(s)	5, 187, 770, 882, 1202
BspANI	GGCC	6 cut(s)	223, 616, 798, 1067, 1151, 1192
BspCNI	CTCAG	6 cut(s)	35, 112, 334, 562, 639, 1161
BspLI	GGNNCC	4 cut(s)	222, 223, 471, 523
BspMAI	CTGCAG	2 cut(s)	328, 975
BspMI	ACCTGC	3 cut(s)	317, 863, 952
BspPI	GGATC	6 cut(s)	464, 477, 516, 529, 766, 1008
BspTNI	GGTCTC	1 cut(s)	908
BsrI	ACTGG	2 cut(s)	635, 798
BssECI	CCNNGG	8 cut(s)	464, 473, 611, 765, 799, 1019, 1113, 1193
BssMI	GATC	6 cut(s)	391, 469, 521, 758, 967, 1000
BssSI	CACGAG	1 cut(s)	1103
BssT1I	CCWWGG	2 cut(s)	464, 765
Bst2BI	CACGAG	1 cut(s)	1103
Bst2UI	CCWGG	2 cut(s)	800, 824
Bst4CI	ACNGT	5 cut(s)	134, 339, 669, 710, 820
Bst6I	CTCTTC	1 cut(s)	399
BstAPI	GCANNNNNTGC	1 cut(s)	332
BstC8I	GCNNGC	3 cut(s)	644, 887, 959
BstDEI	CTNAG	9 cut(s)	22, 99, 342, 446, 570, 647, 673, 1132, 1169
BstDSI	CCRYGG	3 cut(s)	473, 765, 1019
BstF5I	GGATG	5 cut(s)	307, 394, 754, 761, 984
BstKTI	GATC	6 cut(s)	394, 472, 524, 761, 970, 1003
BstMAI	GTCTC	4 cut(s)	341, 787, 809, 908
BstMBI	GATC	6 cut(s)	391, 469, 521, 758, 967, 1000
BstMCI	CGRYCG	1 cut(s)	1152
BstMWI	GCNNNNNNNGC	4 cut(s)	81, 117, 220, 332
BstNI	CCWGG	2 cut(s)	800, 824
BstNSI	RCATGY	1 cut(s)	111
BstSCI	CCNGG	7 cut(s)	610, 611, 798, 822, 1112, 1192, 1193
BstSFI	CTRYAG	3 cut(s)	324, 399, 971
BstSLI	GKGCMC	2 cut(s)	225, 1104
BstV1I	GCAGC	2 cut(s)	310, 1148
BstX2I	RGATCY	3 cut(s)	469, 521, 1000
BstXI	CCANNNNNNTGG	1 cut(s)	793
BstYI	RGATCY	3 cut(s)	469, 521, 1000
BstZI	CGGCCG	1 cut(s)	1149
Bsu36I	CCTNAGG	1 cut(s)	570
BsuRI	GGCC	6 cut(s)	223, 616, 798, 1067, 1151, 1192
BtgI	CCRYGG	3 cut(s)	473, 765, 1019
BtrI	CACGTC	1 cut(s)	79
BtsCI	GGATG	5 cut(s)	307, 394, 754, 761, 984
BtsI	GCAGTG	2 cut(s)	142, 626
BtsIMutI	CAGTG	3 cut(s)	142, 335, 626
BveI	ACCTGC	3 cut(s)	317, 863, 952
Cac8I	GCNNGC	3 cut(s)	644, 887, 959
CaiI	CAGNNNCTG	2 cut(s)	332, 708
Cfr13I	GGNCC	5 cut(s)	221, 222, 614, 796, 1191
Cfr9I	CCCGGG	2 cut(s)	611, 1193
Csp6I	GTAC	3 cut(s)	103, 171, 791
CviAII	CATG	4 cut(s)	108, 298, 766, 1090
CviQI	GTAC	3 cut(s)	103, 171, 791
DdeI	CTNAG	9 cut(s)	22, 99, 342, 446, 570, 647, 673, 1132, 1169
DpnI	GATC	6 cut(s)	393, 471, 523, 760, 969, 1002
DpnII	GATC	6 cut(s)	391, 469, 521, 758, 967, 1000
EaeI	YGGCCR	2 cut(s)	1065, 1149
EagI	CGGCCG	1 cut(s)	1149
Eam1104I	CTCTTC	1 cut(s)	399
EarI	CTCTTC	1 cut(s)	399
EciI	GGCGGA	1 cut(s)	20
EclXI	CGGCCG	1 cut(s)	1149
Eco130I	CCWWGG	2 cut(s)	464, 765
Eco24I	GRGCYC	1 cut(s)	225
Eco31I	GGTCTC	1 cut(s)	908
Eco52I	CGGCCG	1 cut(s)	1149
Eco57I	CTGAAG	3 cut(s)	297, 1025, 1079
Eco81I	CCTNAGG	1 cut(s)	570
Eco88I	CYCGRG	2 cut(s)	611, 1193
EcoO109I	RGGNCCY	1 cut(s)	221
EcoRII	CCWGG	2 cut(s)	798, 822
EcoT14I	CCWWGG	2 cut(s)	464, 765
EcoT38I	GRGCYC	1 cut(s)	225
ErhI	CCWWGG	2 cut(s)	464, 765
FaeI	CATG	4 cut(s)	111, 301, 769, 1093
FaqI	GGGAC	1 cut(s)	28
FatI	CATG	4 cut(s)	107, 297, 765, 1089
FauI	CCCGC	1 cut(s)	180
Fnu4HI	GCNGC	3 cut(s)	324, 883, 1137
FokI	GGATG	5 cut(s)	314, 401, 748, 761, 991
FriOI	GRGCYC	1 cut(s)	225
Fsp4HI	GCNGC	3 cut(s)	324, 883, 1137
FspBI	CTAG	2 cut(s)	50, 935
GluI	GCNGC	3 cut(s)	324, 883, 1137
GsaI	CCCAGC	1 cut(s)	993
HaeIII	GGCC	6 cut(s)	223, 616, 798, 1067, 1151, 1192
HapII	CCGG	5 cut(s)	166, 612, 812, 1113, 1194
Hin1II	CATG	4 cut(s)	111, 301, 769, 1093
HinfI	GANTC	6 cut(s)	8, 176, 557, 604, 897, 1237
HpaII	CCGG	5 cut(s)	166, 612, 812, 1113, 1194
HphI	GGTGA	3 cut(s)	386, 558, 657
Hpy166II	GTNNAC	4 cut(s)	105, 171, 691, 1102
Hpy188I	TCNGA	8 cut(s)	25, 277, 343, 583, 748, 1005, 1012, 1170
Hpy188III	TCNNGA	4 cut(s)	50, 386, 1032, 1241
Hpy8I	GTNNAC	4 cut(s)	105, 171, 691, 1102
HpyAV	CCTTC	3 cut(s)	69, 498, 512
HpyCH4III	ACNGT	5 cut(s)	134, 339, 669, 710, 820
HpyCH4IV	ACGT	2 cut(s)	78, 127
HpyCH4V	TGCA	7 cut(s)	120, 142, 326, 335, 889, 973, 1102
HpyF10VI	GCNNNNNNNGC	4 cut(s)	81, 117, 220, 332
HpyF3I	CTNAG	9 cut(s)	22, 99, 342, 446, 570, 647, 673, 1132, 1169
HpySE526I	ACGT	2 cut(s)	78, 127
Hsp92II	CATG	4 cut(s)	111, 301, 769, 1093
Kzo9I	GATC	6 cut(s)	391, 469, 521, 758, 967, 1000
LmnI	GCTCC	1 cut(s)	863
Lsp1109I	GCAGC	2 cut(s)	310, 1148
LweI	GCATC	2 cut(s)	107, 739
MaeI	CTAG	2 cut(s)	50, 935
MaeII	ACGT	2 cut(s)	78, 127
MaeIII	GTNAC	5 cut(s)	128, 564, 916, 1029, 1144
MalI	GATC	6 cut(s)	393, 471, 523, 760, 969, 1002
MboI	GATC	6 cut(s)	391, 469, 521, 758, 967, 1000
MboII	GAAGA	7 cut(s)	290, 293, 296, 416, 421, 1047, 1219
MfeI	CAATTG	1 cut(s)	215
MflI	RGATCY	3 cut(s)	469, 521, 1000
MhlI	GDGCHC	2 cut(s)	225, 1104
MluCI	AATT	6 cut(s)	92, 215, 577, 890, 1044, 1077
MlyI	GAGTC	1 cut(s)	891
MmeI	TCCRAC	2 cut(s)	559, 990
MroXI	GAANNNNTTC	1 cut(s)	416
MseI	TTAA	2 cut(s)	459, 929
MslI	CAYNNNNRTG	1 cut(s)	770
MspI	CCGG	5 cut(s)	166, 612, 812, 1113, 1194
MspR9I	CCNGG	7 cut(s)	612, 613, 800, 824, 1114, 1194, 1195
MunI	CAATTG	1 cut(s)	215
MvaI	CCWGG	2 cut(s)	800, 824
MwoI	GCNNNNNNNGC	4 cut(s)	81, 117, 220, 332
NciI	CCSGG	5 cut(s)	612, 613, 1114, 1194, 1195
NcoI	CCATGG	1 cut(s)	765
NdeII	GATC	6 cut(s)	391, 469, 521, 758, 967, 1000
NlaIII	CATG	4 cut(s)	111, 301, 769, 1093
NlaIV	GGNNCC	4 cut(s)	222, 223, 471, 523
NmuCI	GTSAC	2 cut(s)	564, 1029
NspI	RCATGY	1 cut(s)	111
PaqCI	CACCTGC	1 cut(s)	952
PcsI	WCGNNNNNNNCGW	1 cut(s)	75
PdmI	GAANNNNTTC	1 cut(s)	416
PfeI	GAWTC	5 cut(s)	8, 176, 557, 604, 1237
PflFI	GACNNNGTC	1 cut(s)	900
PfoI	TCCNGGA	1 cut(s)	822
PkrI	GCNGC	3 cut(s)	325, 884, 1138
PleI	GAGTC	1 cut(s)	891
PpsI	GAGTC	1 cut(s)	891
Psp6I	CCWGG	2 cut(s)	798, 822
PspFI	CCCAGC	1 cut(s)	989
PspGI	CCWGG	2 cut(s)	798, 822
PspN4I	GGNNCC	4 cut(s)	222, 223, 471, 523
PspOMI	GGGCCC	1 cut(s)	221
PspPI	GGNCC	5 cut(s)	221, 222, 614, 796, 1191
PstI	CTGCAG	2 cut(s)	328, 975
PstNI	CAGNNNCTG	2 cut(s)	332, 708
PsuI	RGATCY	3 cut(s)	469, 521, 1000
PsyI	GACNNNGTC	1 cut(s)	900
RsaI	GTAC	3 cut(s)	104, 172, 792
RsaNI	GTAC	3 cut(s)	103, 171, 791
RseI	CAYNNNNRTG	1 cut(s)	770
SaqAI	TTAA	2 cut(s)	459, 929
SatI	GCNGC	3 cut(s)	324, 883, 1137
Sau3AI	GATC	6 cut(s)	391, 469, 521, 758, 967, 1000
Sau96I	GGNCC	5 cut(s)	221, 222, 614, 796, 1191
SchI	GAGTC	1 cut(s)	891
ScrFI	CCNGG	7 cut(s)	612, 613, 800, 824, 1114, 1194, 1195
SduI	GDGCHC	2 cut(s)	225, 1104
SfaNI	GCATC	2 cut(s)	107, 739
SfcI	CTRYAG	3 cut(s)	324, 399, 971
SmaI	CCCGGG	2 cut(s)	613, 1195
SmiMI	CAYNNNNRTG	1 cut(s)	770
Sse9I	AATT	6 cut(s)	92, 215, 577, 890, 1044, 1077
SsiI	CCGC	5 cut(s)	5, 187, 770, 882, 1202
SspMI	CTAG	2 cut(s)	50, 935
StyD4I	CCNGG	7 cut(s)	610, 611, 798, 822, 1112, 1192, 1193
StyI	CCWWGG	2 cut(s)	464, 765
TaaI	ACNGT	5 cut(s)	134, 339, 669, 710, 820
TaiI	ACGT	2 cut(s)	81, 130
TaqI	TCGA	2 cut(s)	115, 1187
TaqII	GACCGA	1 cut(s)	890
TasI	AATT	6 cut(s)	92, 215, 577, 890, 1044, 1077
TatI	WGTACW	2 cut(s)	102, 790
TauI	GCSGC	1 cut(s)	885
TfiI	GAWTC	5 cut(s)	8, 176, 557, 604, 1237
Tru1I	TTAA	2 cut(s)	459, 929
Tru9I	TTAA	2 cut(s)	459, 929
TscAI	CASTG	3 cut(s)	149, 342, 633
TseFI	GTSAC	2 cut(s)	564, 1029
TseI	GCWGC	2 cut(s)	323, 1136
Tsp45I	GTSAC	2 cut(s)	564, 1029
TspDTI	ATGAA	3 cut(s)	570, 671, 1075
TspGWI	ACGGA	4 cut(s)	462, 710, 1036, 1087
TspMI	CCCGGG	2 cut(s)	611, 1193
TspRI	CASTG	3 cut(s)	149, 342, 633
Tth111I	GACNNNGTC	1 cut(s)	900
VneI	GTGCAC	1 cut(s)	1100
XapI	RAATTY	1 cut(s)	1077
XbaI	TCTAGA	1 cut(s)	49
XceI	RCATGY	1 cut(s)	111
XmaI	CCCGGG	2 cut(s)	611, 1193
XmnI	GAANNNNTTC	1 cut(s)	416
XspI	CTAG	2 cut(s)	50, 935

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.