E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates
| Domain Name | Pfam ID | Position | E-value | Description |
|---|---|---|---|---|
| Sina_TRAF | PF03145 | 5 - 101 | 4.2e-35 | Sina, TRAF-like domain |
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| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AccI | GTMKAC | 1 cut(s) | 78 |
| AciI | CCGC | 2 cut(s) | 153, 305 |
| AcsI | RAATTY | 1 cut(s) | 180 |
| AcuI | CTGAAG | 1 cut(s) | 311 |
| AcyI | GRCGYC | 1 cut(s) | 28 |
| AfiI | CCNNNNNNNGG | 1 cut(s) | 211 |
| AluBI | AGCT | 3 cut(s) | 166, 289, 295 |
| AluI | AGCT | 3 cut(s) | 166, 289, 295 |
| Alw26I | GTCTC | 1 cut(s) | 143 |
| AlwNI | CAGNNNCTG | 2 cut(s) | 74, 289 |
| AoxI | GGCC | 3 cut(s) | 84, 117, 307 |
| ApoI | RAATTY | 1 cut(s) | 180 |
| AspS9I | GGNCC | 1 cut(s) | 307 |
| AsuHPI | GGTGA | 1 cut(s) | 116 |
| BccI | CCATC | 2 cut(s) | 17, 224 |
| BceAI | ACGGC | 1 cut(s) | 294 |
| BclI | TGATCA | 1 cut(s) | 237 |
| BcoDI | GTCTC | 1 cut(s) | 143 |
| BmgT120I | GGNCC | 1 cut(s) | 307 |
| BsaHI | GRCGYC | 1 cut(s) | 28 |
| BsaJI | CCNNGG | 1 cut(s) | 185 |
| Bsc4I | CCNNNNNNNGG | 1 cut(s) | 211 |
| BseDI | CCNNGG | 1 cut(s) | 185 |
| BseLI | CCNNNNNNNGG | 1 cut(s) | 211 |
| BseMII | CTCAG | 1 cut(s) | 282 |
| BseRI | GAGGAG | 1 cut(s) | 202 |
| BshFI | GGCC | 3 cut(s) | 86, 119, 309 |
| BslI | CCNNNNNNNGG | 1 cut(s) | 211 |
| BsmAI | GTCTC | 1 cut(s) | 143 |
| BsmI | GAATGC | 1 cut(s) | 53 |
| BsnI | GGCC | 3 cut(s) | 86, 119, 309 |
| Bsp143I | GATC | 1 cut(s) | 237 |
| BspACI | CCGC | 2 cut(s) | 153, 305 |
| BspANI | GGCC | 3 cut(s) | 86, 119, 309 |
| BspCNI | CTCAG | 1 cut(s) | 281 |
| BssECI | CCNNGG | 1 cut(s) | 185 |
| BssMI | GATC | 1 cut(s) | 237 |
| BssNAI | GTATAC | 1 cut(s) | 79 |
| BssNI | GRCGYC | 1 cut(s) | 28 |
| Bst1107I | GTATAC | 1 cut(s) | 79 |
| Bst4CI | ACNGT | 3 cut(s) | 20, 137, 224 |
| Bst6I | CTCTTC | 1 cut(s) | 266 |
| BstACI | GRCGYC | 1 cut(s) | 28 |
| BstC8I | GCNNGC | 2 cut(s) | 41, 307 |
| BstDEI | CTNAG | 2 cut(s) | 92, 268 |
| BstKTI | GATC | 1 cut(s) | 240 |
| BstMAI | GTCTC | 1 cut(s) | 143 |
| BstMBI | GATC | 1 cut(s) | 237 |
| BstMWI | GCNNNNNNNGC | 1 cut(s) | 172 |
| BstZ17I | GTATAC | 1 cut(s) | 79 |
| BsuRI | GGCC | 3 cut(s) | 86, 119, 309 |
| BtsIMutI | CAGTG | 1 cut(s) | 325 |
| Cac8I | GCNNGC | 2 cut(s) | 41, 307 |
| CaiI | CAGNNNCTG | 2 cut(s) | 74, 289 |
| Cfr13I | GGNCC | 1 cut(s) | 307 |
| CseI | GACGC | 1 cut(s) | 17 |
| CviAII | CATG | 3 cut(s) | 82, 100, 171 |
| CviJI | RGCY | 7 cut(s) | 86, 119, 166, 204, 289, 295, 309 |
| CviKI_1 | RGCY | 7 cut(s) | 86, 119, 166, 204, 289, 295, 309 |
| DdeI | CTNAG | 2 cut(s) | 92, 268 |
| DpnI | GATC | 1 cut(s) | 239 |
| DpnII | GATC | 1 cut(s) | 237 |
| Eam1104I | CTCTTC | 1 cut(s) | 266 |
| EarI | CTCTTC | 1 cut(s) | 266 |
| Eco57I | CTGAAG | 1 cut(s) | 311 |
| EcoRI | GAATTC | 1 cut(s) | 180 |
| FaeI | CATG | 3 cut(s) | 85, 103, 174 |
| FaiI | YATR | 6 cut(s) | 79, 83, 101, 172, 314, 316 |
| FatI | CATG | 3 cut(s) | 81, 99, 170 |
| FauI | CCCGC | 1 cut(s) | 298 |
| FbaI | TGATCA | 1 cut(s) | 237 |
| FblI | GTMKAC | 1 cut(s) | 78 |
| HaeIII | GGCC | 3 cut(s) | 86, 119, 309 |
| HgaI | GACGC | 1 cut(s) | 17 |
| Hin1I | GRCGYC | 1 cut(s) | 28 |
| Hin1II | CATG | 3 cut(s) | 85, 103, 174 |
| HincII | GTYRAC | 1 cut(s) | 6 |
| HindII | GTYRAC | 1 cut(s) | 6 |
| HinfI | GANTC | 1 cut(s) | 96 |
| HpaI | GTTAAC | 1 cut(s) | 6 |
| HphI | GGTGA | 1 cut(s) | 116 |
| Hpy166II | GTNNAC | 2 cut(s) | 6, 79 |
| Hpy188I | TCNGA | 2 cut(s) | 186, 246 |
| Hpy188III | TCNNGA | 3 cut(s) | 140, 218, 227 |
| Hpy8I | GTNNAC | 2 cut(s) | 6, 79 |
| HpyAV | CCTTC | 1 cut(s) | 97 |
| HpyCH4III | ACNGT | 3 cut(s) | 20, 137, 224 |
| HpyCH4V | TGCA | 1 cut(s) | 43 |
| HpyF10VI | GCNNNNNNNGC | 1 cut(s) | 172 |
| HpyF3I | CTNAG | 2 cut(s) | 92, 268 |
| Hsp92I | GRCGYC | 1 cut(s) | 28 |
| Hsp92II | CATG | 3 cut(s) | 85, 103, 174 |
| Ksp22I | TGATCA | 1 cut(s) | 237 |
| KspAI | GTTAAC | 1 cut(s) | 6 |
| Kzo9I | GATC | 1 cut(s) | 237 |
| LmnI | GCTCC | 1 cut(s) | 286 |
| LpnPI | CCDG | 3 cut(s) | 87, 255, 269 |
| MaeIII | GTNAC | 1 cut(s) | 218 |
| MalI | GATC | 1 cut(s) | 239 |
| MboI | GATC | 1 cut(s) | 237 |
| MboII | GAAGA | 2 cut(s) | 253, 256 |
| MluCI | AATT | 2 cut(s) | 125, 180 |
| MnlI | CCTC | 4 cut(s) | 43, 109, 180, 240 |
| MseI | TTAA | 2 cut(s) | 5, 15 |
| Mva1269I | GAATGC | 1 cut(s) | 53 |
| MwoI | GCNNNNNNNGC | 1 cut(s) | 172 |
| NdeII | GATC | 1 cut(s) | 237 |
| NlaIII | CATG | 3 cut(s) | 85, 103, 174 |
| NmuCI | GTSAC | 1 cut(s) | 218 |
| PctI | GAATGC | 1 cut(s) | 53 |
| PfeI | GAWTC | 1 cut(s) | 96 |
| PspPI | GGNCC | 1 cut(s) | 307 |
| PstNI | CAGNNNCTG | 2 cut(s) | 74, 289 |
| SaqAI | TTAA | 2 cut(s) | 5, 15 |
| Sau3AI | GATC | 1 cut(s) | 237 |
| Sau96I | GGNCC | 1 cut(s) | 307 |
| SetI | ASST | 6 cut(s) | 76, 168, 216, 274, 291, 297 |
| Sse9I | AATT | 2 cut(s) | 125, 180 |
| SsiI | CCGC | 2 cut(s) | 153, 305 |
| TaaI | ACNGT | 3 cut(s) | 20, 137, 224 |
| TaqI | TCGA | 1 cut(s) | 141 |
| TasI | AATT | 2 cut(s) | 125, 180 |
| TfiI | GAWTC | 1 cut(s) | 96 |
| Tru1I | TTAA | 2 cut(s) | 5, 15 |
| Tru9I | TTAA | 2 cut(s) | 5, 15 |
| TseFI | GTSAC | 1 cut(s) | 218 |
| Tsp45I | GTSAC | 1 cut(s) | 218 |
| TspDTI | ATGAA | 1 cut(s) | 88 |
| XapI | RAATTY | 1 cut(s) | 180 |
| XmiI | GTMKAC | 1 cut(s) | 78 |