MD08G1109600.v1.1

Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr08
OG0000848
Physical Location & Seq
Reverse (-)
9641653 .. 9643575
1923 bp
Loading structure...
UTR
Exon/CDS
Intron
MD08G1109600.v1.1.491

Sequence Viewer

Length: 396 bp
ATGTCGTGGCAGCAGTACGTCGACGACCACCTGATGTGCGATATCGACGGCAACCGCCTCACCGCCGCCGCTATCCTCGGCCAAGACGGCAGCGTTTGGTCTCAGAGCGCCTCTTTCCCTGCGTTTAAGCCTGAGGAGATTGCTGCAATTCTGAAAGATTTCGATCAACCCGGAACACTGGCCCCAACTGGATTATTCCTTGGTGGGACGAAGTATATGGTGATCCAGGGTGAACCCGGCGCTGTCATTCGAGGAAAGAAGGGTTCGGGCGGAATTACTATCAAGAAGACCAGCCAGGCCCTGTTAATCGGTATATATGATGAGCCTGTGACTCCTGGGCAGTGCAACATAGTTGTTGAGAGGCTGGGCGATTACCTTATCGAGCAGGGTCTCTAA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
GO:0000003 GO:0000902 GO:0003006 GO:0003674 GO:0003779 GO:0003785 GO:0005488 GO:0005515 GO:0005575 GO:0005576 GO:0005618 GO:0005622 GO:0005623 GO:0005634 GO:0005730 GO:0005737 GO:0005819 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005938 GO:0006996 GO:0007010 GO:0007015 GO:0007275 GO:0008064 GO:0008092 GO:0008104 GO:0008150 GO:0008154 GO:0009506 GO:0009507 GO:0009524 GO:0009536 GO:0009653 GO:0009791 GO:0009826 GO:0009987 GO:0010229 GO:0010639 GO:0015629 GO:0015630 GO:0016020 GO:0016043 GO:0016049 GO:0022414 GO:0022622 GO:0030029 GO:0030036 GO:0030054 GO:0030312 GO:0030832 GO:0030833 GO:0030837 GO:0031333 GO:0031974 GO:0031981 GO:0032271 GO:0032272 GO:0032501 GO:0032502 GO:0032507 GO:0032535 GO:0032956 GO:0032970 GO:0032989 GO:0033036 GO:0033043 GO:0034613 GO:0040007 GO:0042989 GO:0043226 GO:0043227 GO:0043228 GO:0043229 GO:0043231 GO:0043232 GO:0043233 GO:0043254 GO:0044087 GO:0044422 GO:0044424 GO:0044428 GO:0044430 GO:0044444 GO:0044446 GO:0044464 GO:0045185 GO:0048046 GO:0048364 GO:0048366 GO:0048367 GO:0048519 GO:0048523 GO:0048527 GO:0048528 GO:0048589 GO:0048608 GO:0048731 GO:0048827 GO:0048856 GO:0048869 GO:0050789 GO:0050794 GO:0051128 GO:0051129 GO:0051179 GO:0051235 GO:0051493 GO:0051494 GO:0051641 GO:0051651 GO:0055044 GO:0060560 GO:0061458 GO:0065007 GO:0065008 GO:0070013 GO:0070727 GO:0071840 GO:0071944 GO:0090066 GO:0090567 GO:0090696 GO:0097435 GO:0099402 GO:0099568 GO:0110053 GO:1902903 GO:1902904
KEGG Pathways
Metabolic & Signaling
ko04013 ko04015 ko04810 ko05131 ko05132 map04013 map04015 map04810 map05131 map05132
Pfam Domains
Protein Families
Profilin

Protein Analysis

132

Amino Acids

14.01

Weight (kDa)

4.67

Isoelectric Point (pI)

44.42

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
Profilin PF00235 1 - 131 1.6e-44 Profilin
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccI GTMKAC 1 cut(s) 21
AciI CCGC 5 cut(s) 55, 63, 66, 69, 270
AclWI GGATC 1 cut(s) 217
AcoI YGGCCR 1 cut(s) 79
AfaI GTAC 1 cut(s) 17
AjnI CCWGG 3 cut(s) 225, 294, 334
Alw26I GTCTC 1 cut(s) 105
AlwI GGATC 1 cut(s) 217
AlwNI CAGNNNCTG 1 cut(s) 301
AoxI GGCC 3 cut(s) 79, 180, 297
ApeKI GCWGC 3 cut(s) 10, 90, 143
Asp700I GAANNNNTTC 1 cut(s) 158
AspLEI GCGC 2 cut(s) 110, 242
AspS9I GGNCC 2 cut(s) 181, 298
AsuC2I CCSGG 2 cut(s) 171, 237
AsuHPI GGTGA 3 cut(s) 52, 232, 242
AxyI CCTNAGG 1 cut(s) 132
BbsI GAAGAC 1 cut(s) 293
BbvI GCAGC 3 cut(s) 22, 102, 130
BceAI ACGGC 2 cut(s) 64, 103
BciT130I CCWGG 3 cut(s) 227, 296, 336
BcnI CCSGG 2 cut(s) 171, 237
BcoDI GTCTC 1 cut(s) 105
BfoI RGCGCY 2 cut(s) 111, 243
BglI GCCNNNNNGGC 1 cut(s) 87
BisI GCNGC 5 cut(s) 11, 66, 69, 91, 144
BlsI GCNGC 5 cut(s) 12, 67, 70, 92, 145
Bme1390I CCNGG 5 cut(s) 171, 227, 237, 296, 336
BmgT120I GGNCC 2 cut(s) 181, 298
BmiI GGNNCC 1 cut(s) 183
BmrFI CCNGG 5 cut(s) 171, 227, 237, 296, 336
BpiI GAAGAC 1 cut(s) 293
BpuMI CCSGG 2 cut(s) 171, 237
BsaBI GATNNNNATC 1 cut(s) 162
BsaI GGTCTC 1 cut(s) 105
BsaJI CCNNGG 4 cut(s) 76, 199, 226, 335
Bse1I ACTGG 2 cut(s) 183, 193
Bse21I CCTNAGG 1 cut(s) 132
Bse8I GATNNNNATC 1 cut(s) 162
BseBI CCWGG 3 cut(s) 227, 296, 336
BseDI CCNNGG 4 cut(s) 76, 199, 226, 335
BseJI GATNNNNATC 1 cut(s) 162
BseMII CTCAG 2 cut(s) 116, 123
BseNI ACTGG 2 cut(s) 183, 193
BseRI GAGGAG 1 cut(s) 149
BseXI GCAGC 3 cut(s) 22, 102, 130
BseYI CCCAGC 1 cut(s) 364
BshFI GGCC 3 cut(s) 81, 182, 299
BsiSI CCGG 2 cut(s) 171, 237
BslFI GGGAC 1 cut(s) 220
BsmAI GTCTC 1 cut(s) 105
BsmFI GGGAC 1 cut(s) 220
BsnI GGCC 3 cut(s) 81, 182, 299
Bso31I GGTCTC 1 cut(s) 105
Bsp143I GATC 2 cut(s) 163, 222
BspACI CCGC 5 cut(s) 55, 63, 66, 69, 270
BspANI GGCC 3 cut(s) 81, 182, 299
BspCNI CTCAG 2 cut(s) 115, 124
BspLI GGNNCC 1 cut(s) 183
BspPI GGATC 1 cut(s) 217
BspTNI GGTCTC 1 cut(s) 105
BsrI ACTGG 2 cut(s) 183, 193
BssECI CCNNGG 4 cut(s) 76, 199, 226, 335
BssMI GATC 2 cut(s) 163, 222
BssT1I CCWWGG 1 cut(s) 199
Bst2UI CCWGG 3 cut(s) 227, 296, 336
BstDEI CTNAG 2 cut(s) 102, 132
BstH2I RGCGCY 2 cut(s) 111, 243
BstHHI GCGC 2 cut(s) 110, 242
BstKTI GATC 2 cut(s) 166, 225
BstMAI GTCTC 1 cut(s) 105
BstMBI GATC 2 cut(s) 163, 222
BstMWI GCNNNNNNNGC 1 cut(s) 87
BstNI CCWGG 3 cut(s) 227, 296, 336
BstSCI CCNGG 5 cut(s) 169, 225, 235, 294, 334
BstV1I GCAGC 3 cut(s) 22, 102, 130
BstV2I GAAGAC 1 cut(s) 293
Bsu36I CCTNAGG 1 cut(s) 132
BsuRI GGCC 3 cut(s) 81, 182, 299
BtsI GCAGTG 1 cut(s) 347
BtsIMutI CAGTG 2 cut(s) 176, 347
CaiI CAGNNNCTG 1 cut(s) 301
CfoI GCGC 2 cut(s) 110, 242
Cfr13I GGNCC 2 cut(s) 181, 298
Csp6I GTAC 1 cut(s) 16
CviJI RGCY 7 cut(s) 81, 130, 182, 294, 299, 325, 364
CviKI_1 RGCY 7 cut(s) 81, 130, 182, 294, 299, 325, 364
CviQI GTAC 1 cut(s) 16
DdeI CTNAG 2 cut(s) 102, 132
DpnI GATC 2 cut(s) 165, 224
DpnII GATC 2 cut(s) 163, 222
EaeI YGGCCR 1 cut(s) 79
EciI GGCGGA 1 cut(s) 285
Eco130I CCWWGG 1 cut(s) 199
Eco31I GGTCTC 1 cut(s) 105
Eco32I GATATC 1 cut(s) 43
Eco81I CCTNAGG 1 cut(s) 132
EcoO109I RGGNCCY 1 cut(s) 298
EcoRII CCWGG 3 cut(s) 225, 294, 334
EcoRV GATATC 1 cut(s) 43
EcoT14I CCWWGG 1 cut(s) 199
ErhI CCWWGG 1 cut(s) 199
FaiI YATR 6 cut(s) 216, 218, 314, 316, 318, 350
FaqI GGGAC 1 cut(s) 220
FblI GTMKAC 1 cut(s) 21
Fnu4HI GCNGC 5 cut(s) 11, 66, 69, 91, 144
Fsp4HI GCNGC 5 cut(s) 11, 66, 69, 91, 144
GlaI GCGC 2 cut(s) 109, 241
GluI GCNGC 5 cut(s) 11, 66, 69, 91, 144
GsaI CCCAGC 1 cut(s) 368
HaeII RGCGCY 2 cut(s) 111, 243
HaeIII GGCC 3 cut(s) 81, 182, 299
HapII CCGG 2 cut(s) 171, 237
HhaI GCGC 2 cut(s) 110, 242
Hin6I GCGC 2 cut(s) 108, 240
HinP1I GCGC 2 cut(s) 108, 240
HincII GTYRAC 1 cut(s) 22
HindII GTYRAC 1 cut(s) 22
HinfI GANTC 1 cut(s) 331
HpaII CCGG 2 cut(s) 171, 237
HphI GGTGA 3 cut(s) 52, 232, 242
Hpy166II GTNNAC 2 cut(s) 22, 233
Hpy188I TCNGA 2 cut(s) 105, 153
Hpy188III TCNNGA 1 cut(s) 283
Hpy8I GTNNAC 2 cut(s) 22, 233
Hpy99I CGWCG 3 cut(s) 23, 26, 50
HpyAV CCTTC 1 cut(s) 253
HpyCH4IV ACGT 1 cut(s) 18
HpyCH4V TGCA 2 cut(s) 146, 345
HpyF10VI GCNNNNNNNGC 1 cut(s) 87
HpyF3I CTNAG 2 cut(s) 102, 132
HpySE526I ACGT 1 cut(s) 18
HspAI GCGC 2 cut(s) 108, 240
Kzo9I GATC 2 cut(s) 163, 222
Lsp1109I GCAGC 3 cut(s) 22, 102, 130
MaeII ACGT 1 cut(s) 18
MaeIII GTNAC 1 cut(s) 328
MalI GATC 2 cut(s) 165, 224
MboI GATC 2 cut(s) 163, 222
MboII GAAGA 1 cut(s) 298
MluCI AATT 2 cut(s) 147, 273
MlyI GAGTC 1 cut(s) 325
MnlI CCTC 6 cut(s) 68, 86, 121, 127, 245, 354
MroXI GAANNNNTTC 1 cut(s) 158
MseI TTAA 2 cut(s) 126, 305
MspI CCGG 2 cut(s) 171, 237
MspR9I CCNGG 5 cut(s) 171, 227, 237, 296, 336
MvaI CCWGG 3 cut(s) 227, 296, 336
MwoI GCNNNNNNNGC 1 cut(s) 87
NciI CCSGG 2 cut(s) 171, 237
NdeII GATC 2 cut(s) 163, 222
NlaIV GGNNCC 1 cut(s) 183
NmeAIII GCCGAG 1 cut(s) 57
NmuCI GTSAC 1 cut(s) 328
PdmI GAANNNNTTC 1 cut(s) 158
PkrI GCNGC 5 cut(s) 12, 67, 70, 92, 145
PleI GAGTC 1 cut(s) 325
PpsI GAGTC 1 cut(s) 325
Psp6I CCWGG 3 cut(s) 225, 294, 334
PspFI CCCAGC 1 cut(s) 364
PspGI CCWGG 3 cut(s) 225, 294, 334
PspN4I GGNNCC 1 cut(s) 183
PspPI GGNCC 2 cut(s) 181, 298
PstNI CAGNNNCTG 1 cut(s) 301
RsaI GTAC 1 cut(s) 17
RsaNI GTAC 1 cut(s) 16
SalI GTCGAC 1 cut(s) 20
SaqAI TTAA 2 cut(s) 126, 305
SatI GCNGC 5 cut(s) 11, 66, 69, 91, 144
Sau3AI GATC 2 cut(s) 163, 222
Sau96I GGNCC 2 cut(s) 181, 298
SchI GAGTC 1 cut(s) 325
ScrFI CCNGG 5 cut(s) 171, 227, 237, 296, 336
SetI ASST 3 cut(s) 21, 33, 378
SgrDI CGTCGACG 1 cut(s) 20
Sse9I AATT 2 cut(s) 147, 273
SsiI CCGC 5 cut(s) 55, 63, 66, 69, 270
StyD4I CCNGG 5 cut(s) 169, 225, 235, 294, 334
StyI CCWWGG 1 cut(s) 199
TaiI ACGT 1 cut(s) 21
TaqI TCGA 5 cut(s) 21, 45, 162, 250, 381
TasI AATT 2 cut(s) 147, 273
TauI GCSGC 2 cut(s) 68, 71
Tru1I TTAA 2 cut(s) 126, 305
Tru9I TTAA 2 cut(s) 126, 305
TscAI CASTG 2 cut(s) 183, 347
TseFI GTSAC 1 cut(s) 328
TseI GCWGC 3 cut(s) 10, 90, 143
Tsp45I GTSAC 1 cut(s) 328
TspRI CASTG 2 cut(s) 183, 347
XmiI GTMKAC 1 cut(s) 21
XmnI GAANNNNTTC 1 cut(s) 158
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.