component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation
| Domain Name | Pfam ID | Position | E-value | Description |
|---|---|---|---|---|
| eIF-3c_N | PF05470 | 45 - 102 | 1.7e-14 | Eukaryotic translation initiation factor 3 subunit 8 N-terminus |
Download the Full Tree (.nwk) file, then upload it to any of the following tools to customize colors, fonts, annotations, clades, and branch support.
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AciI | CCGC | 1 cut(s) | 28 |
| AcsI | RAATTY | 2 cut(s) | 17, 312 |
| AgsI | TTSAA | 1 cut(s) | 134 |
| AluBI | AGCT | 4 cut(s) | 153, 191, 264, 298 |
| AluI | AGCT | 4 cut(s) | 153, 191, 264, 298 |
| Alw26I | GTCTC | 1 cut(s) | 86 |
| AoxI | GGCC | 1 cut(s) | 25 |
| ApoI | RAATTY | 2 cut(s) | 17, 312 |
| AspS9I | GGNCC | 1 cut(s) | 25 |
| AsuHPI | GGTGA | 2 cut(s) | 271, 353 |
| AsuII | TTCGAA | 1 cut(s) | 14 |
| BclI | TGATCA | 1 cut(s) | 37 |
| BcoDI | GTCTC | 1 cut(s) | 86 |
| BfaI | CTAG | 2 cut(s) | 99, 309 |
| BisI | GCNGC | 1 cut(s) | 28 |
| BlpI | GCTNAGC | 1 cut(s) | 192 |
| BlsI | GCNGC | 1 cut(s) | 29 |
| BmgT120I | GGNCC | 1 cut(s) | 25 |
| BmiI | GGNNCC | 1 cut(s) | 26 |
| BplI | GAGNNNNNCTC | 2 cut(s) | 137, 169 |
| Bpu1102I | GCTNAGC | 1 cut(s) | 192 |
| Bpu14I | TTCGAA | 1 cut(s) | 14 |
| BseRI | GAGGAG | 2 cut(s) | 104, 218 |
| BshFI | GGCC | 1 cut(s) | 27 |
| BsmAI | GTCTC | 1 cut(s) | 86 |
| BsmBI | CGTCTC | 1 cut(s) | 86 |
| BsnI | GGCC | 1 cut(s) | 27 |
| Bsp119I | TTCGAA | 1 cut(s) | 14 |
| Bsp143I | GATC | 1 cut(s) | 37 |
| Bsp1720I | GCTNAGC | 1 cut(s) | 192 |
| BspACI | CCGC | 1 cut(s) | 28 |
| BspANI | GGCC | 1 cut(s) | 27 |
| BspLI | GGNNCC | 1 cut(s) | 26 |
| BspT104I | TTCGAA | 1 cut(s) | 14 |
| BssMI | GATC | 1 cut(s) | 37 |
| Bst4CI | ACNGT | 1 cut(s) | 220 |
| BstBI | TTCGAA | 1 cut(s) | 14 |
| BstC8I | GCNNGC | 1 cut(s) | 266 |
| BstDEI | CTNAG | 1 cut(s) | 192 |
| BstKTI | GATC | 1 cut(s) | 40 |
| BstMAI | GTCTC | 1 cut(s) | 86 |
| BstMBI | GATC | 1 cut(s) | 37 |
| BsuRI | GGCC | 1 cut(s) | 27 |
| Cac8I | GCNNGC | 1 cut(s) | 266 |
| Cfr13I | GGNCC | 1 cut(s) | 25 |
| CviJI | RGCY | 7 cut(s) | 5, 27, 73, 153, 191, 264, 298 |
| CviKI_1 | RGCY | 7 cut(s) | 5, 27, 73, 153, 191, 264, 298 |
| DdeI | CTNAG | 1 cut(s) | 192 |
| DpnI | GATC | 1 cut(s) | 39 |
| DpnII | GATC | 1 cut(s) | 37 |
| Esp3I | CGTCTC | 1 cut(s) | 86 |
| FaiI | YATR | 2 cut(s) | 248, 338 |
| FbaI | TGATCA | 1 cut(s) | 37 |
| Fnu4HI | GCNGC | 1 cut(s) | 28 |
| Fsp4HI | GCNGC | 1 cut(s) | 28 |
| FspBI | CTAG | 2 cut(s) | 99, 309 |
| GluI | GCNGC | 1 cut(s) | 28 |
| HaeIII | GGCC | 1 cut(s) | 27 |
| HincII | GTYRAC | 1 cut(s) | 223 |
| HindII | GTYRAC | 1 cut(s) | 223 |
| HinfI | GANTC | 3 cut(s) | 59, 198, 272 |
| HphI | GGTGA | 2 cut(s) | 271, 353 |
| Hpy166II | GTNNAC | 1 cut(s) | 223 |
| Hpy188I | TCNGA | 2 cut(s) | 64, 157 |
| Hpy8I | GTNNAC | 1 cut(s) | 223 |
| HpyCH4III | ACNGT | 1 cut(s) | 220 |
| HpyCH4V | TGCA | 1 cut(s) | 268 |
| HpyF3I | CTNAG | 1 cut(s) | 192 |
| Ksp22I | TGATCA | 1 cut(s) | 37 |
| Kzo9I | GATC | 1 cut(s) | 37 |
| LpnPI | CCDG | 5 cut(s) | 7, 44, 87, 168, 254 |
| MaeI | CTAG | 2 cut(s) | 99, 309 |
| MaeIII | GTNAC | 3 cut(s) | 44, 326, 341 |
| MalI | GATC | 1 cut(s) | 39 |
| MboI | GATC | 1 cut(s) | 37 |
| MboII | GAAGA | 1 cut(s) | 77 |
| MluCI | AATT | 4 cut(s) | 17, 129, 312, 333 |
| MlyI | GAGTC | 1 cut(s) | 266 |
| MnlI | CCTC | 3 cut(s) | 82, 139, 196 |
| MseI | TTAA | 3 cut(s) | 105, 177, 352 |
| NdeII | GATC | 1 cut(s) | 37 |
| NlaIV | GGNNCC | 1 cut(s) | 26 |
| NmuCI | GTSAC | 3 cut(s) | 44, 326, 341 |
| NspV | TTCGAA | 1 cut(s) | 14 |
| PfeI | GAWTC | 2 cut(s) | 59, 198 |
| PkrI | GCNGC | 1 cut(s) | 29 |
| PleI | GAGTC | 1 cut(s) | 266 |
| PpsI | GAGTC | 1 cut(s) | 266 |
| PspN4I | GGNNCC | 1 cut(s) | 26 |
| PspPI | GGNCC | 1 cut(s) | 25 |
| SaqAI | TTAA | 3 cut(s) | 105, 177, 352 |
| SatI | GCNGC | 1 cut(s) | 28 |
| Sau3AI | GATC | 1 cut(s) | 37 |
| Sau96I | GGNCC | 1 cut(s) | 25 |
| SchI | GAGTC | 1 cut(s) | 266 |
| SetI | ASST | 6 cut(s) | 155, 193, 266, 300, 343, 352 |
| SfuI | TTCGAA | 1 cut(s) | 14 |
| Sse9I | AATT | 4 cut(s) | 17, 129, 312, 333 |
| SsiI | CCGC | 1 cut(s) | 28 |
| SspMI | CTAG | 2 cut(s) | 99, 309 |
| TaaI | ACNGT | 1 cut(s) | 220 |
| TaqI | TCGA | 3 cut(s) | 8, 14, 201 |
| TasI | AATT | 4 cut(s) | 17, 129, 312, 333 |
| TauI | GCSGC | 1 cut(s) | 30 |
| TfiI | GAWTC | 2 cut(s) | 59, 198 |
| Tru1I | TTAA | 3 cut(s) | 105, 177, 352 |
| Tru9I | TTAA | 3 cut(s) | 105, 177, 352 |
| TseFI | GTSAC | 3 cut(s) | 44, 326, 341 |
| Tsp45I | GTSAC | 3 cut(s) | 44, 326, 341 |
| TspDTI | ATGAA | 1 cut(s) | 302 |
| XapI | RAATTY | 2 cut(s) | 17, 312 |
| XspI | CTAG | 2 cut(s) | 99, 309 |