Rroxscaffold_2G00097270

Mitogen-activated protein kinase kinase

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
rosa_roxburghii
GWHEROQ00000002
OG0001741
Physical Location & Seq
Reverse (-)
18488636 .. 18489676
1041 bp
Loading structure...
UTR
Exon/CDS
Intron
Rroxscaffold_2G00097270.1

Sequence Viewer

Length: 1041 bp
ATGAGACAGAATAATATGAGTCAGATGCCGCCGCCGCCGCCGGGAGGTGTGGCCGCCAGACGGCGTCGTCCTGACCTGAGTCTACCGATGCCGAGGCGGGACACCTCTCTGGCCGTGCCGTTGCCTCTGCCGCCGGGACCGAGCTCGGCTCCGTCCGGGTCCGAGGCCGTGATGATCAACTTCTCCGAGCTGGAGCGAGCGAACCGGATTGGGAGCGGAGCCGGCGGCACGGTCTACAAGGTTATTCACAAGCCGACCGGACGGCTCTACGCGCTGAAAGTCATCTACGGCAACCACGACGAGTCGACCCGGCACCAGATCTGCCGCGAGATCCAAATCCTCCGCGACGTCGATAACCCTAACGTCGTCAAGTGCCACGATATGTTTGACCACAACGGCGAGATCCAGGTGCTGCTGGAGTTCATGGACGGCGGTTCGTTAGAGGGGAAGCACATCGCCAACGAGAAAAGCCTCTCCGACTTGGCACGGCAGATCCTCACCGGATTGGCCTACCTCCACAAACGGCACATCGTCCACCGCGATATCAAGCCTTCGAATCTCTTGATCAACGCCCGGAATCAGGTCAAGATCGCCGATTTCGGGGTCAGCCGGATTTTGGCGCAGACTATGGACCCGTGTAACTCCTCTGTAGGGACCATAGCCTACATGAGCCCGGAGAGGATCAACACCGATCTCAATCAGGGCAGGTACGACGGCTACGCCGGCGATATTTGGAGCCTGGGGGTCAGCATCTTGGAGTTTTACATGGGCCGATTTCCGTTCAATGTGCAGCGGGCTCAGGGAGATTGGGCCAGCTTAATGTGGGCCATTTGTATGTCTCAGCCCCCTGAGGCTCCGCCGACGGCCTCCAGAGAGTTCCGGCATTTCATTGCTTGCTGTTTGCAGAGAGAGCCGAACAGGAGAATGTCGGCGCAGCAGTTGTTGCAGCACCCATTTATCTCCGGCAATGGGGGCGGGCCGCCGCAGGTTCACCAGAATCTGCACACTCTTCTACCGCCGCCACGCCCGCTTCCTTCTTAG
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
GO:0000003 GO:0001932 GO:0001934 GO:0002376 GO:0003006 GO:0003674 GO:0003824 GO:0004672 GO:0004674 GO:0005575 GO:0005622 GO:0005623 GO:0005634 GO:0005737 GO:0006464 GO:0006468 GO:0006521 GO:0006793 GO:0006796 GO:0006807 GO:0006950 GO:0006952 GO:0006955 GO:0007154 GO:0007165 GO:0007275 GO:0007346 GO:0008150 GO:0008152 GO:0008219 GO:0009507 GO:0009532 GO:0009536 GO:0009570 GO:0009605 GO:0009607 GO:0009626 GO:0009791 GO:0009814 GO:0009838 GO:0009889 GO:0009891 GO:0009893 GO:0009908 GO:0009987 GO:0010227 GO:0010229 GO:0010364 GO:0010365 GO:0010562 GO:0010565 GO:0010604 GO:0010817 GO:0012501 GO:0016301 GO:0016310 GO:0016740 GO:0016772 GO:0016773 GO:0019220 GO:0019222 GO:0019538 GO:0022414 GO:0023014 GO:0023052 GO:0031098 GO:0031323 GO:0031325 GO:0031326 GO:0031328 GO:0031335 GO:0031337 GO:0031399 GO:0031401 GO:0032147 GO:0032268 GO:0032270 GO:0032350 GO:0032352 GO:0032501 GO:0032502 GO:0033238 GO:0033240 GO:0033554 GO:0033674 GO:0034050 GO:0035556 GO:0036211 GO:0042325 GO:0042327 GO:0042762 GO:0043085 GO:0043170 GO:0043207 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0043412 GO:0043549 GO:0044093 GO:0044237 GO:0044238 GO:0044260 GO:0044267 GO:0044422 GO:0044424 GO:0044434 GO:0044435 GO:0044444 GO:0044446 GO:0044464 GO:0045087 GO:0045764 GO:0045859 GO:0045860 GO:0045937 GO:0046885 GO:0046886 GO:0048367 GO:0048437 GO:0048518 GO:0048522 GO:0048608 GO:0048731 GO:0048856 GO:0050789 GO:0050790 GO:0050794 GO:0050896 GO:0051171 GO:0051173 GO:0051174 GO:0051176 GO:0051246 GO:0051247 GO:0051338 GO:0051347 GO:0051704 GO:0051707 GO:0051716 GO:0051726 GO:0060255 GO:0061458 GO:0062012 GO:0062013 GO:0065007 GO:0065008 GO:0065009 GO:0071704 GO:0080090 GO:0090567 GO:0098542 GO:0099402 GO:0140096 GO:1900908 GO:1900910 GO:1900911 GO:1900913 GO:1901564
KEGG Pathways
Metabolic & Signaling
ko04016 ko04075 ko04626 map04016 map04075 map04626
Pfam Domains
Protein Families
Pkinase

Protein Analysis

346

Amino Acids

38.45

Weight (kDa)

9.2

Isoelectric Point (pI)

64.35

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
Pkinase PF00069 66 - 320 6.3e-68 Protein kinase domain
PK_Tyr_Ser-Thr PF07714 66 - 316 4.1e-39 Protein tyrosine and serine/threonine kinase
Kinase-like PF14531 150 - 265 5.8e-07 Kinase-like
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AasI GACNNNNNNGTC 1 cut(s) 66
AatII GACGTC 1 cut(s) 351
Acc36I ACCTGC 2 cut(s) 696, 976
AccB1I GGYRCC 1 cut(s) 312
AccBSI CCGCTC 1 cut(s) 216
AccI GTMKAC 3 cut(s) 82, 234, 305
AccII CGCG 4 cut(s) 272, 327, 345, 540
AclWI GGATC 4 cut(s) 325, 397, 487, 689
AcoI YGGCCR 2 cut(s) 51, 111
AcyI GRCGYC 2 cut(s) 64, 348
AfaI GTAC 1 cut(s) 710
AfiI CCNNNNNNNGG 8 cut(s) 41, 44, 60, 580, 600, 616, 651, 969
AgsI TTSAA 1 cut(s) 784
AjnI CCWGG 2 cut(s) 405, 738
AluBI AGCT 3 cut(s) 144, 190, 816
AluI AGCT 3 cut(s) 144, 190, 816
Alw21I GWGCWC 1 cut(s) 146
Alw26I GTCTC 1 cut(s) 843
AlwI GGATC 4 cut(s) 325, 397, 487, 689
AlwNI CAGNNNCTG 2 cut(s) 412, 1000
AoxI GGCC 9 cut(s) 51, 111, 165, 507, 769, 810, 825, 864, 977
ApeKI GCWGC 4 cut(s) 412, 790, 934, 946
AspLEI GCGC 3 cut(s) 274, 622, 934
AspS9I GGNCC 8 cut(s) 137, 159, 631, 654, 769, 810, 825, 977
AsuC2I CCSGG 6 cut(s) 42, 135, 157, 310, 574, 674
AsuHPI GGTGA 2 cut(s) 490, 983
AsuII TTCGAA 1 cut(s) 554
AvaII GGWCC 4 cut(s) 137, 159, 631, 654
AxyI CCTNAGG 1 cut(s) 849
BanI GGYRCC 1 cut(s) 312
BanII GRGCYC 3 cut(s) 146, 674, 799
Bbv12I GWGCWC 1 cut(s) 146
BbvI GCAGC 4 cut(s) 399, 802, 946, 958
BciT130I CCWGG 2 cut(s) 407, 740
BclI TGATCA 2 cut(s) 174, 564
BcnI CCSGG 6 cut(s) 42, 135, 157, 310, 574, 674
BcoDI GTCTC 1 cut(s) 843
BfmI CTRYAG 1 cut(s) 648
BfuAI ACCTGC 2 cut(s) 696, 976
BglII AGATCT 1 cut(s) 318
Bme1390I CCNGG 8 cut(s) 42, 135, 157, 310, 407, 574, 674, 740
Bme18I GGWCC 4 cut(s) 137, 159, 631, 654
BmgT120I GGNCC 8 cut(s) 137, 159, 631, 654, 769, 810, 825, 977
BmiI GGNNCC 9 cut(s) 138, 150, 160, 220, 314, 633, 655, 737, 855
BmrFI CCNGG 8 cut(s) 42, 135, 157, 310, 407, 574, 674, 740
BmsI GCATC 3 cut(s) 15, 78, 759
BoxI GACNNNNGTC 1 cut(s) 78
BplI GAGNNNNNCTC 2 cut(s) 133, 165
BpmI CTGGAG 3 cut(s) 212, 437, 853
Bpu10I CCTNAGC 1 cut(s) 798
Bpu14I TTCGAA 1 cut(s) 554
BpuMI CCSGG 6 cut(s) 42, 135, 157, 310, 574, 674
BsaBI GATNNNNATC 2 cut(s) 335, 696
BsaHI GRCGYC 2 cut(s) 64, 348
BsaJI CCNNGG 3 cut(s) 92, 162, 739
BsaWI WCCGGW 3 cut(s) 204, 257, 500
Bsc4I CCNNNNNNNGG 8 cut(s) 41, 44, 60, 580, 600, 616, 651, 969
Bse118I RCCGGY 2 cut(s) 221, 722
Bse21I CCTNAGG 1 cut(s) 849
Bse3DI GCAATG 2 cut(s) 888, 973
Bse8I GATNNNNATC 2 cut(s) 335, 696
BseBI CCWGG 2 cut(s) 407, 740
BseDI CCNNGG 3 cut(s) 92, 162, 739
BseJI GATNNNNATC 2 cut(s) 335, 696
BseLI CCNNNNNNNGG 8 cut(s) 41, 44, 60, 580, 600, 616, 651, 969
BseMI GCAATG 2 cut(s) 888, 973
BseMII CTCAG 4 cut(s) 68, 812, 840, 854
BseRI GAGGAG 1 cut(s) 634
BseXI GCAGC 4 cut(s) 399, 802, 946, 958
BsgI GTGCAG 2 cut(s) 809, 986
Bsh1236I CGCG 4 cut(s) 272, 327, 345, 540
Bsh1285I CGRYCG 1 cut(s) 258
BshFI GGCC 9 cut(s) 53, 113, 167, 509, 771, 812, 827, 866, 979
BshNI GGYRCC 1 cut(s) 312
BsiEI CGRYCG 1 cut(s) 258
BsiHKAI GWGCWC 1 cut(s) 146
BslFI GGGAC 3 cut(s) 113, 150, 667
BslI CCNNNNNNNGG 8 cut(s) 41, 44, 60, 580, 600, 616, 651, 969
BsmAI GTCTC 1 cut(s) 843
BsmFI GGGAC 3 cut(s) 113, 150, 667
BsnI GGCC 9 cut(s) 53, 113, 167, 509, 771, 812, 827, 866, 979
Bsp119I TTCGAA 1 cut(s) 554
Bsp1286I GDGCHC 3 cut(s) 146, 674, 799
Bsp143I GATC 9 cut(s) 174, 318, 330, 402, 492, 564, 588, 681, 691
BspANI GGCC 9 cut(s) 53, 113, 167, 509, 771, 812, 827, 866, 979
BspCNI CTCAG 4 cut(s) 69, 811, 841, 853
BspFNI CGCG 4 cut(s) 272, 327, 345, 540
BspLI GGNNCC 9 cut(s) 138, 150, 160, 220, 314, 633, 655, 737, 855
BspMI ACCTGC 2 cut(s) 696, 976
BspPI GGATC 4 cut(s) 325, 397, 487, 689
BspT104I TTCGAA 1 cut(s) 554
BspT107I GGYRCC 1 cut(s) 312
BsrBI CCGCTC 1 cut(s) 216
BsrDI GCAATG 2 cut(s) 888, 973
BsrFI RCCGGY 2 cut(s) 221, 722
BssAI RCCGGY 2 cut(s) 221, 722
BssECI CCNNGG 3 cut(s) 92, 162, 739
BssMI GATC 9 cut(s) 174, 318, 330, 402, 492, 564, 588, 681, 691
BssNI GRCGYC 2 cut(s) 64, 348
Bst2UI CCWGG 2 cut(s) 407, 740
Bst4CI ACNGT 1 cut(s) 232
Bst6I CTCTTC 1 cut(s) 1014
BstACI GRCGYC 2 cut(s) 64, 348
BstAPI GCANNNNNTGC 1 cut(s) 943
BstBI TTCGAA 1 cut(s) 554
BstC8I GCNNGC 8 cut(s) 198, 223, 724, 795, 814, 895, 977, 1028
BstDEI CTNAG 5 cut(s) 77, 798, 840, 849, 1038
BstFNI CGCG 4 cut(s) 272, 327, 345, 540
BstHHI GCGC 3 cut(s) 274, 622, 934
BstKTI GATC 9 cut(s) 177, 321, 333, 405, 495, 567, 591, 684, 694
BstMAI GTCTC 1 cut(s) 843
BstMBI GATC 9 cut(s) 174, 318, 330, 402, 492, 564, 588, 681, 691
BstMCI CGRYCG 1 cut(s) 258
BstNI CCWGG 2 cut(s) 407, 740
BstPAI GACNNNNGTC 1 cut(s) 78
BstSCI CCNGG 8 cut(s) 40, 133, 155, 308, 405, 572, 672, 738
BstSFI CTRYAG 1 cut(s) 648
BstUI CGCG 4 cut(s) 272, 327, 345, 540
BstV1I GCAGC 4 cut(s) 399, 802, 946, 958
BstX2I RGATCY 4 cut(s) 318, 330, 402, 492
BstYI RGATCY 4 cut(s) 318, 330, 402, 492
Bsu36I CCTNAGG 1 cut(s) 849
BsuRI GGCC 9 cut(s) 53, 113, 167, 509, 771, 812, 827, 866, 979
BtgZI GCGATG 1 cut(s) 439
BveI ACCTGC 2 cut(s) 696, 976
Cac8I GCNNGC 8 cut(s) 198, 223, 724, 795, 814, 895, 977, 1028
CaiI CAGNNNCTG 2 cut(s) 412, 1000
CfoI GCGC 3 cut(s) 274, 622, 934
Cfr10I RCCGGY 2 cut(s) 221, 722
Cfr13I GGNCC 8 cut(s) 137, 159, 631, 654, 769, 810, 825, 977
CseI GACGC 1 cut(s) 53
Csp6I GTAC 1 cut(s) 709
CviAII CATG 3 cut(s) 424, 667, 766
CviQI GTAC 1 cut(s) 709
DdeI CTNAG 5 cut(s) 77, 798, 840, 849, 1038
DpnI GATC 9 cut(s) 176, 320, 332, 404, 494, 566, 590, 683, 693
DpnII GATC 9 cut(s) 174, 318, 330, 402, 492, 564, 588, 681, 691
DrdI GACNNNNNNGTC 1 cut(s) 66
DseDI GACNNNNNNGTC 1 cut(s) 66
EaeI YGGCCR 2 cut(s) 51, 111
Eam1104I CTCTTC 1 cut(s) 1014
EarI CTCTTC 1 cut(s) 1014
EciI GGCGGA 1 cut(s) 846
Ecl136II GAGCTC 1 cut(s) 144
Eco24I GRGCYC 3 cut(s) 146, 674, 799
Eco32I GATATC 1 cut(s) 544
Eco47I GGWCC 4 cut(s) 137, 159, 631, 654
Eco53kI GAGCTC 1 cut(s) 144
Eco81I CCTNAGG 1 cut(s) 849
EcoICRI GAGCTC 1 cut(s) 144
EcoRII CCWGG 2 cut(s) 405, 738
EcoRV GATATC 1 cut(s) 544
EcoT38I GRGCYC 3 cut(s) 146, 674, 799
FaeI CATG 3 cut(s) 427, 670, 769
FaiI YATR 8 cut(s) 17, 383, 425, 629, 659, 668, 767, 836
FaqI GGGAC 3 cut(s) 113, 150, 667
FatI CATG 3 cut(s) 423, 666, 765
FauI CCCGC 4 cut(s) 90, 786, 968, 1035
FbaI TGATCA 2 cut(s) 174, 564
FblI GTMKAC 3 cut(s) 82, 234, 305
FriOI GRGCYC 3 cut(s) 146, 674, 799
GlaI GCGC 3 cut(s) 273, 621, 933
GsuI CTGGAG 3 cut(s) 212, 437, 853
HaeIII GGCC 9 cut(s) 53, 113, 167, 509, 771, 812, 827, 866, 979
HgaI GACGC 1 cut(s) 53
HhaI GCGC 3 cut(s) 274, 622, 934
Hin1I GRCGYC 2 cut(s) 64, 348
Hin1II CATG 3 cut(s) 427, 670, 769
Hin6I GCGC 3 cut(s) 272, 620, 932
HinP1I GCGC 3 cut(s) 272, 620, 932
HincII GTYRAC 1 cut(s) 306
HindII GTYRAC 1 cut(s) 306
HinfI GANTC 6 cut(s) 19, 79, 302, 556, 577, 997
HphI GGTGA 2 cut(s) 490, 983
Hpy166II GTNNAC 5 cut(s) 83, 235, 306, 535, 991
Hpy188I TCNGA 4 cut(s) 24, 163, 187, 478
Hpy188III TCNNGA 4 cut(s) 71, 562, 586, 870
Hpy8I GTNNAC 5 cut(s) 83, 235, 306, 535, 991
Hpy99I CGWCG 7 cut(s) 69, 302, 350, 353, 368, 716, 865
HpyAV CCTTC 1 cut(s) 561
HpyCH4III ACNGT 1 cut(s) 232
HpyCH4IV ACGT 2 cut(s) 348, 363
HpyCH4V TGCA 4 cut(s) 790, 904, 946, 1003
HpyF3I CTNAG 5 cut(s) 77, 798, 840, 849, 1038
HpySE526I ACGT 2 cut(s) 348, 363
Hsp92I GRCGYC 2 cut(s) 64, 348
Hsp92II CATG 3 cut(s) 427, 670, 769
HspAI GCGC 3 cut(s) 272, 620, 932
KroI GCCGGC 2 cut(s) 221, 722
KroNI GCCGGC 2 cut(s) 223, 724
Ksp22I TGATCA 2 cut(s) 174, 564
Kzo9I GATC 9 cut(s) 174, 318, 330, 402, 492, 564, 588, 681, 691
LmnI GCTCC 6 cut(s) 154, 193, 213, 218, 735, 859
Lsp1109I GCAGC 4 cut(s) 399, 802, 946, 958
LweI GCATC 3 cut(s) 15, 78, 759
MaeII ACGT 2 cut(s) 348, 363
MaeIII GTNAC 1 cut(s) 638
MalI GATC 9 cut(s) 176, 320, 332, 404, 494, 566, 590, 683, 693
MbiI CCGCTC 1 cut(s) 216
MboI GATC 9 cut(s) 174, 318, 330, 402, 492, 564, 588, 681, 691
MboII GAAGA 1 cut(s) 1001
MflI RGATCY 4 cut(s) 318, 330, 402, 492
MhlI GDGCHC 3 cut(s) 146, 674, 799
MlyI GAGTC 3 cut(s) 28, 88, 311
MmeI TCCRAC 1 cut(s) 501
MreI CGCCGGCG 1 cut(s) 722
MroNI GCCGGC 2 cut(s) 221, 722
MseI TTAA 1 cut(s) 818
MslI CAYNNNNRTG 1 cut(s) 833
MspA1I CMGCKG 1 cut(s) 793
MspR9I CCNGG 8 cut(s) 42, 135, 157, 310, 407, 574, 674, 740
MvaI CCWGG 2 cut(s) 407, 740
MvnI CGCG 4 cut(s) 272, 327, 345, 540
NaeI GCCGGC 2 cut(s) 223, 724
NciI CCSGG 6 cut(s) 42, 135, 157, 310, 574, 674
NdeII GATC 9 cut(s) 174, 318, 330, 402, 492, 564, 588, 681, 691
NgoMIV GCCGGC 2 cut(s) 221, 722
NlaIII CATG 3 cut(s) 427, 670, 769
NlaIV GGNNCC 9 cut(s) 138, 150, 160, 220, 314, 633, 655, 737, 855
NmeAIII GCCGAG 2 cut(s) 117, 125
NspV TTCGAA 1 cut(s) 554
PcsI WCGNNNNNNNCGW 2 cut(s) 294, 537
PdiI GCCGGC 2 cut(s) 223, 724
PfeI GAWTC 3 cut(s) 556, 577, 997
PflFI GACNNNGTC 1 cut(s) 63
PleI GAGTC 3 cut(s) 27, 87, 310
PpsI GAGTC 3 cut(s) 27, 87, 310
PshAI GACNNNNGTC 1 cut(s) 78
Psp124BI GAGCTC 1 cut(s) 146
Psp6I CCWGG 2 cut(s) 405, 738
PspGI CCWGG 2 cut(s) 405, 738
PspN4I GGNNCC 9 cut(s) 138, 150, 160, 220, 314, 633, 655, 737, 855
PspPI GGNCC 8 cut(s) 137, 159, 631, 654, 769, 810, 825, 977
PstNI CAGNNNCTG 2 cut(s) 412, 1000
PsuI RGATCY 4 cut(s) 318, 330, 402, 492
PsyI GACNNNGTC 1 cut(s) 63
RsaI GTAC 1 cut(s) 710
RsaNI GTAC 1 cut(s) 709
RseI CAYNNNNRTG 1 cut(s) 833
SacI GAGCTC 1 cut(s) 146
SalI GTCGAC 1 cut(s) 304
SaqAI TTAA 1 cut(s) 818
Sau3AI GATC 9 cut(s) 174, 318, 330, 402, 492, 564, 588, 681, 691
Sau96I GGNCC 8 cut(s) 137, 159, 631, 654, 769, 810, 825, 977
SchI GAGTC 3 cut(s) 28, 88, 311
ScrFI CCNGG 8 cut(s) 42, 135, 157, 310, 407, 574, 674, 740
SduI GDGCHC 3 cut(s) 146, 674, 799
SfaNI GCATC 3 cut(s) 15, 78, 759
SfcI CTRYAG 1 cut(s) 648
SfuI TTCGAA 1 cut(s) 554
SgrAI CRCCGGYG 1 cut(s) 722
SinI GGWCC 4 cut(s) 137, 159, 631, 654
SmiMI CAYNNNNRTG 1 cut(s) 833
SstI GAGCTC 1 cut(s) 146
StyD4I CCNGG 8 cut(s) 40, 133, 155, 308, 405, 572, 672, 738
TaaI ACNGT 1 cut(s) 232
TaiI ACGT 2 cut(s) 351, 366
TaqI TCGA 3 cut(s) 305, 351, 554
TaqII GACCGA 1 cut(s) 154
TfiI GAWTC 3 cut(s) 556, 577, 997
Tru1I TTAA 1 cut(s) 818
Tru9I TTAA 1 cut(s) 818
TseI GCWGC 4 cut(s) 412, 790, 934, 946
TspDTI ATGAA 2 cut(s) 412, 877
TspGWI ACGGA 2 cut(s) 141, 768
Tth111I GACNNNGTC 1 cut(s) 63
VpaK11BI GGWCC 4 cut(s) 137, 159, 631, 654
XmiI GTMKAC 3 cut(s) 82, 234, 305
ZraI GACGTC 1 cut(s) 349
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.