Basic Information

Type: gene

Biological Identity

Species

malus_domestica

Chromosome

Chr17

Orthogroup ID

OG0001260

Physical Location & Seq

Genomic Coordinates Reverse (-)

9626527 .. 9629218

Gene Structure 2692 bp

Loading structure...

UTR

Exon/CDS

Intron

Transcript / Protein ID

MD17G1112400.v1.1.491

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1053 bp

ATGAAAAAGCAAAGTTTGCGTCGTTATTACATCGCCATACGACGTCGTCGTAGCCAGTGCTCCCCGCTTCCCGGCGGTTATAAAAACCGCCTTCCCTTTGAACAGTCACAATTTCCAATTCTTCTTCTCTCTCTCTGCGTCCAAGAGCTTCACTGCGTTTGCCCAAGAATCTCAAGTATCGCCATGCCAGTTGGGAATTCGAATGCATCTGATCGGGATGCTGAACCATTTGTGGAGGTTGATCCAACTGGACGGTATGGGCGGTATGCTGATCTCCTTGGTCATGGTGCTGTGAAGAAGGTTTATAGGGCTTTTGATCAGGAGGATGGTATAGAGGTGGCCTGGAATAAGGTCCGGTTGTGCAATTTCAGTGACGATCCAACACTCATTAATCGGCTTTACTCTGAGGTTAAGCTGTTGAGGCAATTGAAGAACAAGTATATCATTGTTTGTCACAGTGTTTGGAAGGAAGAGGCGCATAACACTTTGAATTTTATCACTGAGGTGTGCAATTCTGGAAACCTGAGGAAGTACAGGGAGAAGCATCCCCGTGTGTCGCTTAAGGCTCTGAAGAAGTGGTCGAGACAGGTGCTTGAGGGATTGGAATACCTCCATACGCATGAGCCGTGCATCATTCACAGAGATCTTAATTGCAGCAACATCTTCATCAACGGGAATACTGGCCAAGTGAAAATTGGTGATCTGGGGTTTGCAGCAATAGTGGGAAAGAACCACTTAGCACATTCGATTATAGGTACACCCGAGTACATGGCGCCCGAGCTGTATGAAGAGGATTACACAGAGATGGTGGACATATACTCGTTCGGGCTGTGCTTGCTGGAGATGGTGACAATGGAGATACCATACAGCGAGTGCGACTCTGTTGCTAAGATATACAAGAAGGTGACAACAGGTATCAAGCCTTTAGCATTGAACAAGGTGAACGATCCAGAGGTGAAGGCGTTCATTGAGAAAGCCATAGCCCAGCCGAGGGCAAGACCTACAGCCTCTGATCTTCTCAGGGATCCCTTCTTGTCTGAAGTCAATCAGTAA

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0003674 GO:0003824 GO:0004672 GO:0004674 GO:0005575 GO:0005622 GO:0005623 GO:0005737 GO:0005829 GO:0006464 GO:0006468 GO:0006793 GO:0006796 GO:0006807 GO:0007154 GO:0007165 GO:0008150 GO:0008152 GO:0009987 GO:0016301 GO:0016310 GO:0016740 GO:0016772 GO:0016773 GO:0019538 GO:0023052 GO:0035556 GO:0036211 GO:0043170 GO:0043412 GO:0044237 GO:0044238 GO:0044260 GO:0044267 GO:0044424 GO:0044444 GO:0044464 GO:0050789 GO:0050794 GO:0050896 GO:0051716 GO:0065007 GO:0071704 GO:0140096 GO:1901564

KEGG Pathways

Metabolic & Signaling

No pathways identified.

Pfam Domains

Protein Families

Pkinase

Protein Analysis

351

Amino Acids

39.96

Weight (kDa)

8.64

Isoelectric Point (pI)

43.63

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
Pkinase	PF00069	91 - 345	1.6e-49	Protein kinase domain
PK_Tyr_Ser-Thr	PF07714	91 - 341	1e-32	Protein tyrosine and serine/threonine kinase

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

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Orthologous Genes (Group: OG0001260)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT5G55560
fragaria_vesca	FvH4_3g22150 FvH4_6g41240
malus_domestica	MD03G1189000.v1.1 MD09G1121400.v1.1 MD11G1205200.v1.1 MD17G1112400.v1.1
prunus_persica	Prupe.3G202300_v2.0.a1 Prupe.3G202300_v2.0.a1 Prupe.3G202300_v2.0.a1 Prupe.3G202300_v2.0.a1 Prupe.3G202300_v2.0.a1 Prupe.3G202300_v2.0.a1 Prupe.4G232100_v2.0.a1 Prupe.4G232100_v2.0.a1
pyrus_communis	pycom03g14190 pycom03g14210 pycom09g04580 pycom11g17800 pycom17g10410
rosa_chinensis	RchiOBHm_Chr2g0156791 RchiOBHm_Chr5g0038001 RchiOBHm_Chr5g0038041 RchiOBHm_Chr5g0042541
rosa_laevigata	RLG00000020942 RLG00000034135
rosa_multiflora	Rmu_co8331393.1_g000001 Rmu_co8390513.1_g000001 Rmu_sc0002670.1_g000011 Rmu_sc0008149.1_g000008 Rmu_sc0008278.1_g000004
rosa_roxburghii	Rroxscaffold_1G00038120 Rroxscaffold_1G00042890 Rroxscaffold_2G00092720
rosa_rugosa	Rorug02G0456200 Rorug05G0170100 Rorug05G0201300 Rorug05G0201400
rosa_samantha	Rh2AG521800 Rh2BG535200 Rh2CG506700 Rh2DG544200 Rh5BG261300 Rh5BG261600 Rh5BG291700 Rh5CG293600 Rh5CG323900 Rh5DG270500 Rh5DG270600 Rh5DG301500
rosa_wichuraiana	Rw2G043080 Rw5G023930 Rw5G024110 Rw5G024140 Rw5G026670

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AanI	TTATAA	1 cut(s)	81
AatII	GACGTC	1 cut(s)	46
AccB1I	GGYRCC	1 cut(s)	772
AciI	CCGC	4 cut(s)	65, 75, 88, 262
AclWI	GGATC	5 cut(s)	236, 371, 941, 1019, 1032
AcoI	YGGCCR	1 cut(s)	682
AcsI	RAATTY	2 cut(s)	196, 490
AcuI	CTGAAG	1 cut(s)	590
AcyI	GRCGYC	2 cut(s)	43, 773
AfaI	GTAC	3 cut(s)	533, 757, 767
AfiI	CCNNNNNNNGG	3 cut(s)	71, 990, 991
AflII	CTTAAG	1 cut(s)	560
AgsI	TTSAA	4 cut(s)	101, 430, 490, 934
AjnI	CCWGG	1 cut(s)	341
AleI	CACNNNNGTG	1 cut(s)	503
AluBI	AGCT	3 cut(s)	148, 415, 781
AluI	AGCT	3 cut(s)	148, 415, 781
Alw21I	GWGCWC	1 cut(s)	62
Alw26I	GTCTC	1 cut(s)	577
AlwI	GGATC	5 cut(s)	236, 371, 941, 1019, 1032
AlwNI	CAGNNNCTG	1 cut(s)	1010
Ama87I	CYCGRG	2 cut(s)	761, 776
AoxI	GGCC	2 cut(s)	339, 682
ApeKI	GCWGC	2 cut(s)	654, 713
ApoI	RAATTY	2 cut(s)	196, 490
ArsI	GACNNNNNNTTYG	1 cut(s)	36
AseI	ATTAAT	1 cut(s)	390
Asp700I	GAANNNNTTC	1 cut(s)	962
AspLEI	GCGC	2 cut(s)	478, 775
AspS9I	GGNCC	1 cut(s)	352
AsuC2I	CCSGG	1 cut(s)	72
AsuHPI	GGTGA	5 cut(s)	710, 859, 916, 952, 967
AsuII	TTCGAA	1 cut(s)	200
AvaI	CYCGRG	2 cut(s)	761, 776
AvaII	GGWCC	1 cut(s)	352
AxyI	CCTNAGG	1 cut(s)	524
BalI	TGGCCA	1 cut(s)	684
BamHI	GGATCC	1 cut(s)	1024
BanI	GGYRCC	1 cut(s)	772
Bbv12I	GWGCWC	1 cut(s)	62
BbvI	GCAGC	2 cut(s)	666, 725
BccI	CCATC	3 cut(s)	320, 799, 838
BceAI	ACGGC	1 cut(s)	610
BcgI	CGANNNNNNTGC	4 cut(s)	571, 605, 866, 900
BciT130I	CCWGG	1 cut(s)	343
BclI	TGATCA	1 cut(s)	316
BcnI	CCSGG	1 cut(s)	72
BcoDI	GTCTC	1 cut(s)	577
BfmI	CTRYAG	1 cut(s)	1002
BfoI	RGCGCY	1 cut(s)	776
BfrI	CTTAAG	1 cut(s)	560
BglII	AGATCT	1 cut(s)	643
BisI	GCNGC	2 cut(s)	655, 714
BlsI	GCNGC	2 cut(s)	656, 715
Bme1390I	CCNGG	2 cut(s)	72, 343
Bme18I	GGWCC	1 cut(s)	352
BmeT110I	CYCGRG	2 cut(s)	761, 776
BmgT120I	GGNCC	1 cut(s)	352
BmiI	GGNNCC	2 cut(s)	774, 1026
BmrFI	CCNGG	2 cut(s)	72, 343
BmsI	GCATC	4 cut(s)	208, 215, 553, 639
BplI	GAGNNNNNCTC	2 cut(s)	863, 895
BpmI	CTGGAG	1 cut(s)	860
Bpu14I	TTCGAA	1 cut(s)	200
BpuEI	CTTGAG	2 cut(s)	157, 614
BpuMI	CCSGG	1 cut(s)	72
BsaHI	GRCGYC	2 cut(s)	43, 773
BsaJI	CCNNGG	2 cut(s)	277, 989
BsaWI	WCCGGW	1 cut(s)	354
Bsc4I	CCNNNNNNNGG	3 cut(s)	71, 990, 991
Bse1I	ACTGG	4 cut(s)	55, 188, 253, 685
Bse21I	CCTNAGG	1 cut(s)	524
BseBI	CCWGG	1 cut(s)	343
BseDI	CCNNGG	2 cut(s)	277, 989
BseGI	GGATG	3 cut(s)	223, 331, 544
BseLI	CCNNNNNNNGG	3 cut(s)	71, 990, 991
BseMII	CTCAG	4 cut(s)	396, 492, 515, 1033
BseNI	ACTGG	4 cut(s)	55, 188, 253, 685
BseXI	GCAGC	2 cut(s)	666, 725
BseYI	CCCAGC	1 cut(s)	984
BshFI	GGCC	2 cut(s)	341, 684
BshNI	GGYRCC	1 cut(s)	772
BsiHKAI	GWGCWC	1 cut(s)	62
BsiHKCI	CYCGRG	2 cut(s)	761, 776
BsiSI	CCGG	2 cut(s)	72, 355
BslI	CCNNNNNNNGG	3 cut(s)	71, 990, 991
BsmAI	GTCTC	1 cut(s)	577
BsmI	GAATGC	1 cut(s)	208
BsnI	GGCC	2 cut(s)	341, 684
BsoBI	CYCGRG	2 cut(s)	761, 776
Bsp119I	TTCGAA	1 cut(s)	200
Bsp1286I	GDGCHC	1 cut(s)	62
BspACI	CCGC	4 cut(s)	65, 75, 88, 262
BspANI	GGCC	2 cut(s)	341, 684
BspCNI	CTCAG	4 cut(s)	397, 493, 516, 1032
BspLI	GGNNCC	2 cut(s)	774, 1026
BspPI	GGATC	5 cut(s)	236, 371, 941, 1019, 1032
BspT104I	TTCGAA	1 cut(s)	200
BspT107I	GGYRCC	1 cut(s)	772
BspTI	CTTAAG	1 cut(s)	560
BsrI	ACTGG	4 cut(s)	55, 188, 253, 685
BssECI	CCNNGG	2 cut(s)	277, 989
BssNI	GRCGYC	2 cut(s)	43, 773
BssT1I	CCWWGG	1 cut(s)	277
Bst2UI	CCWGG	1 cut(s)	343
Bst4CI	ACNGT	3 cut(s)	105, 255, 458
Bst6I	CTCTTC	2 cut(s)	465, 783
BstACI	GRCGYC	2 cut(s)	43, 773
BstAFI	CTTAAG	1 cut(s)	560
BstAPI	GCANNNNNTGC	1 cut(s)	16
BstBI	TTCGAA	1 cut(s)	200
BstC8I	GCNNGC	1 cut(s)	836
BstDEI	CTNAG	6 cut(s)	405, 501, 524, 736, 888, 1019
BstF5I	GGATG	3 cut(s)	223, 331, 544
BstH2I	RGCGCY	1 cut(s)	776
BstHHI	GCGC	2 cut(s)	478, 775
BstMAI	GTCTC	1 cut(s)	577
BstMWI	GCNNNNNNNGC	3 cut(s)	16, 421, 835
BstNI	CCWGG	1 cut(s)	343
BstSCI	CCNGG	2 cut(s)	70, 341
BstSFI	CTRYAG	1 cut(s)	1002
BstV1I	GCAGC	2 cut(s)	666, 725
BstX2I	RGATCY	2 cut(s)	643, 1024
BstYI	RGATCY	2 cut(s)	643, 1024
Bsu36I	CCTNAGG	1 cut(s)	524
BsuRI	GGCC	2 cut(s)	341, 684
BtgZI	GCGATG	1 cut(s)	16
BtsCI	GGATG	3 cut(s)	223, 331, 544
BtsI	GCAGTG	1 cut(s)	151
BtsIMutI	CAGTG	5 cut(s)	62, 151, 376, 463, 498
Cac8I	GCNNGC	1 cut(s)	836
CaiI	CAGNNNCTG	1 cut(s)	1010
CfoI	GCGC	2 cut(s)	478, 775
Cfr13I	GGNCC	1 cut(s)	352
CseI	GACGC	2 cut(s)	8, 127
Csp6I	GTAC	3 cut(s)	532, 756, 766
CviAII	CATG	4 cut(s)	184, 284, 620, 769
CviQI	GTAC	3 cut(s)	532, 756, 766
DdeI	CTNAG	6 cut(s)	405, 501, 524, 736, 888, 1019
DinI	GGCGCC	1 cut(s)	774
EaeI	YGGCCR	1 cut(s)	682
Eam1104I	CTCTTC	2 cut(s)	465, 783
EarI	CTCTTC	2 cut(s)	465, 783
Eco130I	CCWWGG	1 cut(s)	277
Eco47I	GGWCC	1 cut(s)	352
Eco57I	CTGAAG	1 cut(s)	590
Eco81I	CCTNAGG	1 cut(s)	524
Eco88I	CYCGRG	2 cut(s)	761, 776
EcoRI	GAATTC	1 cut(s)	196
EcoRII	CCWGG	1 cut(s)	341
EcoT14I	CCWWGG	1 cut(s)	277
EcoT22I	ATGCAT	1 cut(s)	208
EgeI	GGCGCC	1 cut(s)	774
EheI	GGCGCC	1 cut(s)	774
ErhI	CCWWGG	1 cut(s)	277
FaeI	CATG	4 cut(s)	187, 287, 623, 772
FalI	AAGNNNNNCTT	2 cut(s)	719, 751
FatI	CATG	4 cut(s)	183, 283, 619, 768
FauI	CCCGC	1 cut(s)	72
FbaI	TGATCA	1 cut(s)	316
Fnu4HI	GCNGC	2 cut(s)	655, 714
FokI	GGATG	3 cut(s)	230, 338, 531
Fsp4HI	GCNGC	2 cut(s)	655, 714
GlaI	GCGC	2 cut(s)	477, 774
GluI	GCNGC	2 cut(s)	655, 714
GsaI	CCCAGC	1 cut(s)	988
GsuI	CTGGAG	1 cut(s)	860
HaeII	RGCGCY	1 cut(s)	776
HaeIII	GGCC	2 cut(s)	341, 684
HapII	CCGG	2 cut(s)	72, 355
HgaI	GACGC	2 cut(s)	8, 127
HhaI	GCGC	2 cut(s)	478, 775
Hin1I	GRCGYC	2 cut(s)	43, 773
Hin1II	CATG	4 cut(s)	187, 287, 623, 772
Hin6I	GCGC	2 cut(s)	476, 773
HinP1I	GCGC	2 cut(s)	476, 773
HinfI	GANTC	2 cut(s)	168, 878
HpaII	CCGG	2 cut(s)	72, 355
HphI	GGTGA	5 cut(s)	710, 859, 916, 952, 967
Hpy166II	GTNNAC	3 cut(s)	758, 811, 943
Hpy188I	TCNGA	5 cut(s)	211, 406, 570, 1012, 1039
Hpy188III	TCNNGA	5 cut(s)	215, 320, 516, 582, 950
Hpy8I	GTNNAC	3 cut(s)	758, 811, 943
Hpy99I	CGWCG	4 cut(s)	24, 45, 48, 51
HpyAV	CCTTC	6 cut(s)	101, 292, 460, 895, 952, 1039
HpyCH4III	ACNGT	3 cut(s)	105, 255, 458
HpyCH4IV	ACGT	1 cut(s)	43
HpyCH4V	TGCA	6 cut(s)	206, 363, 510, 630, 654, 713
HpyF10VI	GCNNNNNNNGC	3 cut(s)	16, 421, 835
HpyF3I	CTNAG	6 cut(s)	405, 501, 524, 736, 888, 1019
HpySE526I	ACGT	1 cut(s)	43
Hsp92I	GRCGYC	2 cut(s)	43, 773
Hsp92II	CATG	4 cut(s)	187, 287, 623, 772
HspAI	GCGC	2 cut(s)	476, 773
KasI	GGCGCC	1 cut(s)	772
Ksp22I	TGATCA	1 cut(s)	316
LmnI	GCTCC	1 cut(s)	65
Lsp1109I	GCAGC	2 cut(s)	666, 725
LweI	GCATC	4 cut(s)	208, 215, 553, 639
MaeII	ACGT	1 cut(s)	43
MaeIII	GTNAC	5 cut(s)	105, 371, 452, 847, 904
MboII	GAAGA	9 cut(s)	113, 116, 307, 442, 482, 583, 655, 800, 1007
MfeI	CAATTG	1 cut(s)	425
MflI	RGATCY	2 cut(s)	643, 1024
MhlI	GDGCHC	1 cut(s)	62
MlsI	TGGCCA	1 cut(s)	684
MluCI	AATT	9 cut(s)	110, 117, 196, 364, 425, 490, 511, 649, 693
MluNI	TGGCCA	1 cut(s)	684
Mly113I	GGCGCC	1 cut(s)	773
MlyI	GAGTC	1 cut(s)	872
MmeI	TCCRAC	2 cut(s)	269, 404
Mox20I	TGGCCA	1 cut(s)	684
Mph1103I	ATGCAT	1 cut(s)	208
MroXI	GAANNNNTTC	1 cut(s)	962
MscI	TGGCCA	1 cut(s)	684
MseI	TTAA	4 cut(s)	390, 411, 561, 648
MslI	CAYNNNNRTG	4 cut(s)	503, 549, 618, 803
Msp20I	TGGCCA	1 cut(s)	684
MspCI	CTTAAG	1 cut(s)	560
MspI	CCGG	2 cut(s)	72, 355
MspR9I	CCNGG	2 cut(s)	72, 343
MunI	CAATTG	1 cut(s)	425
Mva1269I	GAATGC	1 cut(s)	208
MvaI	CCWGG	1 cut(s)	343
MwoI	GCNNNNNNNGC	3 cut(s)	16, 421, 835
NarI	GGCGCC	1 cut(s)	773
NciI	CCSGG	1 cut(s)	72
NlaIII	CATG	4 cut(s)	187, 287, 623, 772
NlaIV	GGNNCC	2 cut(s)	774, 1026
NmeAIII	GCCGAG	1 cut(s)	1014
NmuCI	GTSAC	5 cut(s)	105, 371, 452, 847, 904
NsiI	ATGCAT	1 cut(s)	208
NspV	TTCGAA	1 cut(s)	200
OliI	CACNNNNGTG	1 cut(s)	503
PcsI	WCGNNNNNNNCGW	2 cut(s)	46, 623
PctI	GAATGC	1 cut(s)	208
PdmI	GAANNNNTTC	1 cut(s)	962
PfeI	GAWTC	1 cut(s)	168
PflFI	GACNNNGTC	1 cut(s)	45
PkrI	GCNGC	2 cut(s)	656, 715
PleI	GAGTC	1 cut(s)	872
PluTI	GGCGCC	1 cut(s)	776
PpsI	GAGTC	1 cut(s)	872
PshBI	ATTAAT	1 cut(s)	390
PsiI	TTATAA	1 cut(s)	81
Psp6I	CCWGG	1 cut(s)	341
PspFI	CCCAGC	1 cut(s)	984
PspGI	CCWGG	1 cut(s)	341
PspN4I	GGNNCC	2 cut(s)	774, 1026
PspPI	GGNCC	1 cut(s)	352
PstNI	CAGNNNCTG	1 cut(s)	1010
PsuI	RGATCY	2 cut(s)	643, 1024
PsyI	GACNNNGTC	1 cut(s)	45
RsaI	GTAC	3 cut(s)	533, 757, 767
RsaNI	GTAC	3 cut(s)	532, 756, 766
RseI	CAYNNNNRTG	4 cut(s)	503, 549, 618, 803
SaqAI	TTAA	4 cut(s)	390, 411, 561, 648
SatI	GCNGC	2 cut(s)	655, 714
Sau96I	GGNCC	1 cut(s)	352
SchI	GAGTC	1 cut(s)	872
ScrFI	CCNGG	2 cut(s)	72, 343
SduI	GDGCHC	1 cut(s)	62
SfaNI	GCATC	4 cut(s)	208, 215, 553, 639
SfcI	CTRYAG	1 cut(s)	1002
SfoI	GGCGCC	1 cut(s)	774
SfuI	TTCGAA	1 cut(s)	200
SinI	GGWCC	1 cut(s)	352
SmiMI	CAYNNNNRTG	4 cut(s)	503, 549, 618, 803
SmlI	CTYRAG	3 cut(s)	172, 560, 593
SmoI	CTYRAG	3 cut(s)	172, 560, 593
Sse9I	AATT	9 cut(s)	110, 117, 196, 364, 425, 490, 511, 649, 693
SsiI	CCGC	4 cut(s)	65, 75, 88, 262
SspDI	GGCGCC	1 cut(s)	772
StyD4I	CCNGG	2 cut(s)	70, 341
StyI	CCWWGG	1 cut(s)	277
TaaI	ACNGT	3 cut(s)	105, 255, 458
TaiI	ACGT	1 cut(s)	46
TaqI	TCGA	3 cut(s)	200, 581, 746
TasI	AATT	9 cut(s)	110, 117, 196, 364, 425, 490, 511, 649, 693
TatI	WGTACW	2 cut(s)	531, 765
TfiI	GAWTC	1 cut(s)	168
Tru1I	TTAA	4 cut(s)	390, 411, 561, 648
Tru9I	TTAA	4 cut(s)	390, 411, 561, 648
TscAI	CASTG	5 cut(s)	62, 158, 376, 463, 505
TseFI	GTSAC	5 cut(s)	105, 371, 452, 847, 904
TseI	GCWGC	2 cut(s)	654, 713
Tsp45I	GTSAC	5 cut(s)	105, 371, 452, 847, 904
TspDTI	ATGAA	4 cut(s)	17, 655, 801, 955
TspRI	CASTG	5 cut(s)	62, 158, 376, 463, 505
Tth111I	GACNNNGTC	1 cut(s)	45
Vha464I	CTTAAG	1 cut(s)	560
VpaK11BI	GGWCC	1 cut(s)	352
VspI	ATTAAT	1 cut(s)	390
XapI	RAATTY	2 cut(s)	196, 490
XcmI	CCANNNNNNNNNTGG	1 cut(s)	692
XmnI	GAANNNNTTC	1 cut(s)	962
ZraI	GACGTC	1 cut(s)	44
Zsp2I	ATGCAT	1 cut(s)	208

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.