MD06G1152200.v1.1

Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr06
OG0001670
Physical Location & Seq
Forward (+)
29588123 .. 29592447
4325 bp
Loading structure...
UTR
Exon/CDS
Intron
MD06G1152200.v1.1.491

Sequence Viewer

Length: 876 bp
ATGATTGCAACTCTGCCGGAGTCAGACAGTAAAGCTCTTCTCCCCAAGCTCCGGGTCAAGCCGGTCCCAACCGCTTCGGGCATCGTCGTCGTGGCCGGGATGTCGAAGCCTCATCGGTGGCCCCACATCGCCACTACCGGAAATATTTGCGTGTACTGCCCCGACGGTCCCGATTCGGACTTCGAGCATAGCACTCAATCTTACACTGGATACGAGCCTACTAGCAATTCGGGCAAGGTCGAGTTCATCTTAATGGGCGGTACTTTCATGACGTTGCCCGTGGATTACCGTGATTACTTTATTAGAAATCTGCACGATGCATTATCGGGACACACTTCTGCCAATGCTGAAGAGGCTTTTGCCTACTCTGAGCATGGTGCTACTAAATTTCATCTGGTGGTTGCACACATGATGCCTGATCTTCCAAATGTAGGGGTGGAGAGAGACATGGAGAGTTTTCGGGAGTTCTTTGAGATTCCCTTGTTCAGAGCAGATGGGCTTAAAATTTATCCAACACTCGTGATCCGTGGAACTGGACTCTATGAGCTTTGGAAAACGGGCAGGTATAGAAATTACCCACCTGAGCAACTTGTGGACATTGTAGCTCGGATCCTAGCCATGGTCCCCCCTTGGACGCGTGTTTATAGAGTTCAGCAAGACATTCCAATGCCTTTAGTTACTTCTGGGGTTGAGAAAGGAAATCTTCGGGGGTTAGCTTTTGCATGGATGGAAGACTTGGGCTTGAAGTGCCGTGAGAGGCTGGAATTCAGGCCAGACCAAGTGGAGCTTGTTCGTCGTGATTATATGGCAAATGAAGGATGGGAAACATTTCTTTCATATGAAGATACTCGCCAGGTATTCGTTCTTTATATGTGA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
GO:0000228 GO:0000785 GO:0000790 GO:0000791 GO:0002097 GO:0002098 GO:0003674 GO:0003824 GO:0004402 GO:0005575 GO:0005622 GO:0005623 GO:0005634 GO:0005694 GO:0005719 GO:0005737 GO:0005829 GO:0006139 GO:0006325 GO:0006355 GO:0006357 GO:0006396 GO:0006399 GO:0006400 GO:0006464 GO:0006473 GO:0006475 GO:0006725 GO:0006807 GO:0006996 GO:0007275 GO:0007389 GO:0008033 GO:0008080 GO:0008150 GO:0008152 GO:0008283 GO:0009292 GO:0009294 GO:0009451 GO:0009653 GO:0009798 GO:0009889 GO:0009966 GO:0009987 GO:0010467 GO:0010468 GO:0010556 GO:0010646 GO:0010928 GO:0016043 GO:0016070 GO:0016407 GO:0016410 GO:0016569 GO:0016570 GO:0016573 GO:0016740 GO:0016746 GO:0016747 GO:0018193 GO:0018205 GO:0018393 GO:0018394 GO:0019219 GO:0019222 GO:0019538 GO:0022603 GO:0023051 GO:0031323 GO:0031326 GO:0031974 GO:0031981 GO:0032501 GO:0032502 GO:0032991 GO:0033588 GO:0034212 GO:0034470 GO:0034641 GO:0034660 GO:0035265 GO:0036211 GO:0040007 GO:0043170 GO:0043226 GO:0043227 GO:0043228 GO:0043229 GO:0043231 GO:0043232 GO:0043233 GO:0043412 GO:0043543 GO:0044237 GO:0044238 GO:0044260 GO:0044267 GO:0044422 GO:0044424 GO:0044427 GO:0044428 GO:0044444 GO:0044446 GO:0044454 GO:0044464 GO:0044764 GO:0046483 GO:0048583 GO:0048589 GO:0048731 GO:0048831 GO:0048856 GO:0050789 GO:0050793 GO:0050794 GO:0051171 GO:0051239 GO:0051252 GO:0051276 GO:0051704 GO:0060255 GO:0061733 GO:0065001 GO:0065007 GO:0070013 GO:0071704 GO:0071840 GO:0080090 GO:0090304 GO:0090708 GO:0099402 GO:1900618 GO:1901360 GO:1901371 GO:1901564 GO:1903506 GO:1905392 GO:1905421 GO:1905428 GO:2000024 GO:2000025 GO:2000026 GO:2000112 GO:2001141
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
Acetyltransf_1 Radical_SAM Radical_SAM_C

Protein Analysis

292

Amino Acids

33.18

Weight (kDa)

5.66

Isoelectric Point (pI)

34.86

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
Radical_SAM_C PF16199 165 - 238 2.1e-21 Radical_SAM C-terminal domain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

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Publication-ready
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
Acc36I ACCTGC 1 cut(s) 552
AccII CGCG 1 cut(s) 637
AciI CCGC 2 cut(s) 72, 258
AclWI GGATC 3 cut(s) 517, 604, 617
AcoI YGGCCR 1 cut(s) 93
AcsI RAATTY 3 cut(s) 386, 504, 764
AcuI CTGAAG 1 cut(s) 369
AfaI GTAC 2 cut(s) 155, 262
AfiI CCNNNNNNNGG 3 cut(s) 51, 431, 619
AflIII ACRYGT 1 cut(s) 635
AgsI TTSAA 1 cut(s) 745
AjnI CCWGG 1 cut(s) 852
AluBI AGCT 6 cut(s) 35, 49, 547, 605, 716, 787
AluI AGCT 6 cut(s) 35, 49, 547, 605, 716, 787
Alw26I GTCTC 1 cut(s) 438
AlwI GGATC 3 cut(s) 517, 604, 617
AoxI GGCC 3 cut(s) 93, 119, 770
ApoI RAATTY 3 cut(s) 386, 504, 764
Asp700I GAANNNNTTC 1 cut(s) 828
AspS9I GGNCC 4 cut(s) 64, 120, 167, 622
AsuC2I CCSGG 2 cut(s) 53, 97
AvaII GGWCC 3 cut(s) 64, 167, 622
BamHI GGATCC 1 cut(s) 609
BauI CACGAG 1 cut(s) 518
BbsI GAAGAC 1 cut(s) 738
BccI CCATC 3 cut(s) 488, 721, 813
BceAI ACGGC 1 cut(s) 735
BcgI CGANNNNNNTGC 2 cut(s) 70, 104
BciT130I CCWGG 1 cut(s) 854
BciVI GTATCC 1 cut(s) 203
BcnI CCSGG 2 cut(s) 53, 97
BcoDI GTCTC 1 cut(s) 438
BfaI CTAG 2 cut(s) 222, 614
BfuAI ACCTGC 1 cut(s) 552
BfuI GTATCC 1 cut(s) 203
Bme1390I CCNGG 3 cut(s) 53, 97, 854
Bme18I GGWCC 3 cut(s) 64, 167, 622
BmgT120I GGNCC 4 cut(s) 64, 120, 167, 622
BmiI GGNNCC 5 cut(s) 66, 122, 169, 611, 624
BmrFI CCNGG 3 cut(s) 53, 97, 854
BmsI GCATC 3 cut(s) 90, 307, 402
BpiI GAAGAC 1 cut(s) 738
Bpu10I CCTNAGC 1 cut(s) 582
BpuMI CCSGG 2 cut(s) 53, 97
BsaJI CCNNGG 4 cut(s) 279, 526, 618, 629
BsaWI WCCGGW 1 cut(s) 137
Bsc4I CCNNNNNNNGG 3 cut(s) 51, 431, 619
Bse118I RCCGGY 1 cut(s) 61
Bse1I ACTGG 2 cut(s) 211, 538
BseBI CCWGG 1 cut(s) 854
BseDI CCNNGG 4 cut(s) 279, 526, 618, 629
BseGI GGATG 3 cut(s) 105, 732, 824
BseLI CCNNNNNNNGG 3 cut(s) 51, 431, 619
BseMII CTCAG 2 cut(s) 360, 573
BseNI ACTGG 2 cut(s) 211, 538
BsgI GTGCAG 1 cut(s) 296
Bsh1236I CGCG 1 cut(s) 637
BshFI GGCC 3 cut(s) 95, 121, 772
BsiSI CCGG 5 cut(s) 17, 52, 62, 96, 138
BslFI GGGAC 4 cut(s) 50, 153, 342, 608
BslI CCNNNNNNNGG 3 cut(s) 51, 431, 619
BsmAI GTCTC 1 cut(s) 438
BsmFI GGGAC 4 cut(s) 50, 153, 342, 608
BsnI GGCC 3 cut(s) 95, 121, 772
Bsp143I GATC 3 cut(s) 418, 522, 609
Bsp19I CCATGG 1 cut(s) 618
BspACI CCGC 2 cut(s) 72, 258
BspANI GGCC 3 cut(s) 95, 121, 772
BspCNI CTCAG 2 cut(s) 361, 574
BspFNI CGCG 1 cut(s) 637
BspHI TCATGA 1 cut(s) 267
BspLI GGNNCC 5 cut(s) 66, 122, 169, 611, 624
BspMI ACCTGC 1 cut(s) 552
BspPI GGATC 3 cut(s) 517, 604, 617
BspQI GCTCTTC 1 cut(s) 42
BsrFI RCCGGY 1 cut(s) 61
BsrI ACTGG 2 cut(s) 211, 538
BssAI RCCGGY 1 cut(s) 61
BssECI CCNNGG 4 cut(s) 279, 526, 618, 629
BssMI GATC 3 cut(s) 418, 522, 609
BssSI CACGAG 1 cut(s) 518
BssT1I CCWWGG 2 cut(s) 618, 629
Bst2BI CACGAG 1 cut(s) 518
Bst2UI CCWGG 1 cut(s) 854
Bst4CI ACNGT 3 cut(s) 29, 167, 290
Bst6I CTCTTC 2 cut(s) 42, 345
BstDEI CTNAG 2 cut(s) 369, 582
BstDSI CCRYGG 3 cut(s) 279, 526, 618
BstF5I GGATG 3 cut(s) 105, 732, 824
BstFNI CGCG 1 cut(s) 637
BstKTI GATC 3 cut(s) 421, 525, 612
BstMAI GTCTC 1 cut(s) 438
BstMBI GATC 3 cut(s) 418, 522, 609
BstMWI GCNNNNNNNGC 4 cut(s) 156, 231, 353, 747
BstNI CCWGG 1 cut(s) 854
BstSCI CCNGG 3 cut(s) 51, 95, 852
BstUI CGCG 1 cut(s) 637
BstV2I GAAGAC 1 cut(s) 738
BstX2I RGATCY 1 cut(s) 609
BstYI RGATCY 1 cut(s) 609
BsuI GTATCC 1 cut(s) 203
BsuRI GGCC 3 cut(s) 95, 121, 772
BtgI CCRYGG 3 cut(s) 279, 526, 618
BtgZI GCGATG 1 cut(s) 112
BtsCI GGATG 3 cut(s) 105, 732, 824
BtsIMutI CAGTG 1 cut(s) 204
BveI ACCTGC 1 cut(s) 552
CciI TCATGA 1 cut(s) 267
Cfr10I RCCGGY 1 cut(s) 61
Cfr13I GGNCC 4 cut(s) 64, 120, 167, 622
CseI GACGC 1 cut(s) 643
Csp6I GTAC 2 cut(s) 154, 261
CviAII CATG 6 cut(s) 268, 374, 409, 448, 619, 723
CviQI GTAC 2 cut(s) 154, 261
DdeI CTNAG 2 cut(s) 369, 582
DpnI GATC 3 cut(s) 420, 524, 611
DpnII GATC 3 cut(s) 418, 522, 609
EaeI YGGCCR 1 cut(s) 93
Eam1104I CTCTTC 2 cut(s) 42, 345
EarI CTCTTC 2 cut(s) 42, 345
Eco130I CCWWGG 2 cut(s) 618, 629
Eco47I GGWCC 3 cut(s) 64, 167, 622
Eco57I CTGAAG 1 cut(s) 369
EcoRI GAATTC 1 cut(s) 764
EcoRII CCWGG 1 cut(s) 852
EcoT14I CCWWGG 2 cut(s) 618, 629
EcoT22I ATGCAT 1 cut(s) 322
ErhI CCWWGG 2 cut(s) 618, 629
FaeI CATG 6 cut(s) 271, 377, 412, 451, 622, 726
FalI AAGNNNNNCTT 4 cut(s) 687, 719, 771, 803
FaqI GGGAC 4 cut(s) 50, 153, 342, 608
FatI CATG 6 cut(s) 267, 373, 408, 447, 618, 722
FauNDI CATATG 1 cut(s) 838
FokI GGATG 3 cut(s) 112, 739, 831
FspBI CTAG 2 cut(s) 222, 614
HaeIII GGCC 3 cut(s) 95, 121, 772
HapII CCGG 5 cut(s) 17, 52, 62, 96, 138
HgaI GACGC 1 cut(s) 643
Hin1II CATG 6 cut(s) 271, 377, 412, 451, 622, 726
HinfI GANTC 4 cut(s) 20, 173, 475, 537
HpaII CCGG 5 cut(s) 17, 52, 62, 96, 138
Hpy166II GTNNAC 2 cut(s) 154, 595
Hpy188I TCNGA 5 cut(s) 25, 178, 370, 488, 609
Hpy188III TCNNGA 6 cut(s) 170, 268, 327, 461, 520, 797
Hpy8I GTNNAC 2 cut(s) 154, 595
Hpy99I CGWCG 4 cut(s) 89, 92, 167, 798
HpyAV CCTTC 1 cut(s) 809
HpyCH4III ACNGT 3 cut(s) 29, 167, 290
HpyCH4IV ACGT 1 cut(s) 272
HpyCH4V TGCA 5 cut(s) 8, 313, 320, 404, 722
HpyF10VI GCNNNNNNNGC 4 cut(s) 156, 231, 353, 747
HpyF3I CTNAG 2 cut(s) 369, 582
HpySE526I ACGT 1 cut(s) 272
Hsp92II CATG 6 cut(s) 271, 377, 412, 451, 622, 726
Kzo9I GATC 3 cut(s) 418, 522, 609
LguI GCTCTTC 1 cut(s) 42
LmnI GCTCC 2 cut(s) 54, 784
LweI GCATC 3 cut(s) 90, 307, 402
MaeI CTAG 2 cut(s) 222, 614
MaeII ACGT 1 cut(s) 272
MaeIII GTNAC 1 cut(s) 676
MalI GATC 3 cut(s) 420, 524, 611
MboI GATC 3 cut(s) 418, 522, 609
MboII GAAGA 6 cut(s) 29, 362, 413, 695, 743, 854
MflI RGATCY 1 cut(s) 609
MluCI AATT 5 cut(s) 226, 386, 504, 571, 764
MluI ACGCGT 1 cut(s) 635
MlyI GAGTC 2 cut(s) 29, 531
MmeI TCCRAC 1 cut(s) 536
MnlI CCTC 3 cut(s) 120, 346, 750
Mph1103I ATGCAT 1 cut(s) 322
MroXI GAANNNNTTC 1 cut(s) 828
MseI TTAA 2 cut(s) 251, 501
MslI CAYNNNNRTG 2 cut(s) 251, 665
MspI CCGG 5 cut(s) 17, 52, 62, 96, 138
MspR9I CCNGG 3 cut(s) 53, 97, 854
MvaI CCWGG 1 cut(s) 854
MvnI CGCG 1 cut(s) 637
MwoI GCNNNNNNNGC 4 cut(s) 156, 231, 353, 747
NciI CCSGG 2 cut(s) 53, 97
NcoI CCATGG 1 cut(s) 618
NdeI CATATG 1 cut(s) 838
NdeII GATC 3 cut(s) 418, 522, 609
NlaIII CATG 6 cut(s) 271, 377, 412, 451, 622, 726
NlaIV GGNNCC 5 cut(s) 66, 122, 169, 611, 624
NsiI ATGCAT 1 cut(s) 322
PagI TCATGA 1 cut(s) 267
PciSI GCTCTTC 1 cut(s) 42
PdmI GAANNNNTTC 1 cut(s) 828
PfeI GAWTC 2 cut(s) 173, 475
PleI GAGTC 2 cut(s) 28, 531
PpsI GAGTC 2 cut(s) 28, 531
Psp6I CCWGG 1 cut(s) 852
PspGI CCWGG 1 cut(s) 852
PspN4I GGNNCC 5 cut(s) 66, 122, 169, 611, 624
PspPI GGNCC 4 cut(s) 64, 120, 167, 622
PsuI RGATCY 1 cut(s) 609
RsaI GTAC 2 cut(s) 155, 262
RsaNI GTAC 2 cut(s) 154, 261
RseI CAYNNNNRTG 2 cut(s) 251, 665
SapI GCTCTTC 1 cut(s) 42
SaqAI TTAA 2 cut(s) 251, 501
Sau3AI GATC 3 cut(s) 418, 522, 609
Sau96I GGNCC 4 cut(s) 64, 120, 167, 622
SchI GAGTC 2 cut(s) 29, 531
ScrFI CCNGG 3 cut(s) 53, 97, 854
SfaNI GCATC 3 cut(s) 90, 307, 402
SinI GGWCC 3 cut(s) 64, 167, 622
SmiMI CAYNNNNRTG 2 cut(s) 251, 665
Sse9I AATT 5 cut(s) 226, 386, 504, 571, 764
SsiI CCGC 2 cut(s) 72, 258
SspI AATATT 1 cut(s) 145
SspMI CTAG 2 cut(s) 222, 614
StyD4I CCNGG 3 cut(s) 51, 95, 852
StyI CCWWGG 2 cut(s) 618, 629
TaaI ACNGT 3 cut(s) 29, 167, 290
TaiI ACGT 1 cut(s) 275
TaqI TCGA 3 cut(s) 104, 183, 240
TasI AATT 5 cut(s) 226, 386, 504, 571, 764
TatI WGTACW 1 cut(s) 153
TfiI GAWTC 2 cut(s) 173, 475
Tru1I TTAA 2 cut(s) 251, 501
Tru9I TTAA 2 cut(s) 251, 501
TscAI CASTG 1 cut(s) 211
TspDTI ATGAA 6 cut(s) 235, 256, 380, 825, 828, 855
TspGWI ACGGA 1 cut(s) 515
TspRI CASTG 1 cut(s) 211
VpaK11BI GGWCC 3 cut(s) 64, 167, 622
XapI RAATTY 3 cut(s) 386, 504, 764
XmnI GAANNNNTTC 1 cut(s) 828
XspI CTAG 2 cut(s) 222, 614
Zsp2I ATGCAT 1 cut(s) 322
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.