MD06G1156700.v1.1

Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr06
OG0001670
Physical Location & Seq
Forward (+)
29910418 .. 29911874
1457 bp
Loading structure...
UTR
Exon/CDS
Intron
MD06G1156700.v1.1.491

Sequence Viewer

Length: 744 bp
ATGTCGAAGCCTCATAGGTGCCCCCACATCGCCACCACCGGGAATATTTGCGTGTACTGCCCCGGTGGTCCCGATTCGGACTTTGAGTACAGCACTCAGTCTTACACTGGATACGAGCCTACTAGCATGCGCGCAATTTGGGCAGATACAACCCATATGTCCAGGCTAGAAGATCAGCTGAAGAGATTGGGTCACAGTGTAGACAAGGTCGAGTTCATCTTAATGGGCGGTACTTTCATGTCGTTGCCCGCAGATTACCGTGATTACTTTATTAGAAATCTGCACGATGCGTTATTGGGACACACTTCTGCCAATGTTGAAGAGGCAGTTGCCTACTCTGAGCATGGTGCTACTAAATTAATTTTTCGCTTACCATCTTGTTTCCAGTTCATCTGGTCGGTCCAGAAAGTTAACAAAGGTAGTTGTAACTTTTTATTCTGCTGGAGGCCAGATTATTGCCTTGGACCTCACTTGAGACAAATGCTTTCTTATGGTTGTACAAGACTAGAAATTGGAGTTCAGAGTACATATGAGGATGTGGCTCGGGACAACAATAGAGGTCATACCGTAGCTGCAGTGGCTGATTGTTTTTACTTGGCAAAGGATGCTGGTTTTAAGGTGGTTGCACACATGATGCCTGACCTTCCTAATGTAGGGGTTGAGAGAGACATGGAGAATTTCGGGAGTTCTTTGAGAGCCCCTCGTTCAGAGAAAATGGCCCTAAAATTTAACCAACACTCGTGA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
GO:0000228 GO:0000785 GO:0000790 GO:0000791 GO:0002097 GO:0002098 GO:0003674 GO:0003824 GO:0004402 GO:0005575 GO:0005622 GO:0005623 GO:0005634 GO:0005694 GO:0005719 GO:0005737 GO:0005829 GO:0006139 GO:0006325 GO:0006355 GO:0006357 GO:0006396 GO:0006399 GO:0006400 GO:0006464 GO:0006473 GO:0006475 GO:0006725 GO:0006807 GO:0006996 GO:0007275 GO:0007389 GO:0008033 GO:0008080 GO:0008150 GO:0008152 GO:0008283 GO:0009292 GO:0009294 GO:0009451 GO:0009653 GO:0009798 GO:0009889 GO:0009966 GO:0009987 GO:0010467 GO:0010468 GO:0010556 GO:0010646 GO:0010928 GO:0016043 GO:0016070 GO:0016407 GO:0016410 GO:0016569 GO:0016570 GO:0016573 GO:0016740 GO:0016746 GO:0016747 GO:0018193 GO:0018205 GO:0018393 GO:0018394 GO:0019219 GO:0019222 GO:0019538 GO:0022603 GO:0023051 GO:0031323 GO:0031326 GO:0031974 GO:0031981 GO:0032501 GO:0032502 GO:0032991 GO:0033588 GO:0034212 GO:0034470 GO:0034641 GO:0034660 GO:0035265 GO:0036211 GO:0040007 GO:0043170 GO:0043226 GO:0043227 GO:0043228 GO:0043229 GO:0043231 GO:0043232 GO:0043233 GO:0043412 GO:0043543 GO:0044237 GO:0044238 GO:0044260 GO:0044267 GO:0044422 GO:0044424 GO:0044427 GO:0044428 GO:0044444 GO:0044446 GO:0044454 GO:0044464 GO:0044764 GO:0046483 GO:0048583 GO:0048589 GO:0048731 GO:0048831 GO:0048856 GO:0050789 GO:0050793 GO:0050794 GO:0051171 GO:0051239 GO:0051252 GO:0051276 GO:0051704 GO:0060255 GO:0061733 GO:0065001 GO:0065007 GO:0070013 GO:0071704 GO:0071840 GO:0080090 GO:0090304 GO:0090708 GO:0099402 GO:1900618 GO:1901360 GO:1901371 GO:1901564 GO:1903506 GO:1905392 GO:1905421 GO:1905428 GO:2000024 GO:2000025 GO:2000026 GO:2000112 GO:2001141
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
Acetyltransf_1 Radical_SAM Radical_SAM_C

Protein Analysis

248

Amino Acids

27.9

Weight (kDa)

6.58

Isoelectric Point (pI)

39.94

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
Radical_SAM PF04055 157 - 219 1.5e-08 Radical SAM superfamily
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccB1I GGYRCC 1 cut(s) 18
AccI GTMKAC 1 cut(s) 201
AccII CGCG 1 cut(s) 132
AciI CCGC 2 cut(s) 228, 249
AcsI RAATTY 2 cut(s) 676, 725
AcuI CTGAAG 1 cut(s) 200
AfaI GTAC 5 cut(s) 56, 89, 232, 499, 526
AfiI CCNNNNNNNGG 2 cut(s) 39, 653
AgsI TTSAA 1 cut(s) 320
AjnI CCWGG 1 cut(s) 161
AluBI AGCT 2 cut(s) 178, 572
AluI AGCT 2 cut(s) 178, 572
Alw26I GTCTC 2 cut(s) 469, 660
AlwNI CAGNNNCTG 1 cut(s) 581
Ama87I CYCGRG 1 cut(s) 543
AoxI GGCC 2 cut(s) 446, 717
ApeKI GCWGC 1 cut(s) 572
ApoI RAATTY 2 cut(s) 676, 725
AseI ATTAAT 1 cut(s) 359
AspLEI GCGC 2 cut(s) 132, 134
AspS9I GGNCC 4 cut(s) 68, 400, 464, 718
AsuC2I CCSGG 2 cut(s) 40, 63
AvaI CYCGRG 1 cut(s) 543
AvaII GGWCC 3 cut(s) 68, 400, 464
BaeGI GKGCMC 1 cut(s) 23
BanI GGYRCC 1 cut(s) 18
BanII GRGCYC 1 cut(s) 700
BauI CACGAG 1 cut(s) 739
BbvI GCAGC 1 cut(s) 559
BccI CCATC 1 cut(s) 382
BciT130I CCWGG 1 cut(s) 163
BciVI GTATCC 1 cut(s) 104
BcnI CCSGG 2 cut(s) 40, 63
BcoDI GTCTC 2 cut(s) 469, 660
BfaI CTAG 3 cut(s) 123, 167, 506
BfmI CTRYAG 1 cut(s) 573
BfuI GTATCC 1 cut(s) 104
BisI GCNGC 1 cut(s) 573
BlsI GCNGC 1 cut(s) 574
Bme1390I CCNGG 3 cut(s) 40, 63, 163
Bme18I GGWCC 3 cut(s) 68, 400, 464
BmeT110I CYCGRG 1 cut(s) 543
BmgT120I GGNCC 4 cut(s) 68, 400, 464, 718
BmiI GGNNCC 2 cut(s) 20, 70
BmrFI CCNGG 3 cut(s) 40, 63, 163
BmsI GCATC 3 cut(s) 277, 595, 624
BplI GAGNNNNNCTC 2 cut(s) 685, 717
BpmI CTGGAG 1 cut(s) 463
BpuEI CTTGAG 1 cut(s) 493
BpuMI CCSGG 2 cut(s) 40, 63
BsaJI CCNNGG 2 cut(s) 61, 460
Bsc4I CCNNNNNNNGG 2 cut(s) 39, 653
Bse1I ACTGG 2 cut(s) 112, 385
BseBI CCWGG 1 cut(s) 163
BseDI CCNNGG 2 cut(s) 61, 460
BseGI GGATG 2 cut(s) 541, 610
BseLI CCNNNNNNNGG 2 cut(s) 39, 653
BseMII CTCAG 2 cut(s) 110, 330
BseNI ACTGG 2 cut(s) 112, 385
BsePI GCGCGC 1 cut(s) 130
BseSI GKGCMC 1 cut(s) 23
BseXI GCAGC 1 cut(s) 559
BsgI GTGCAG 1 cut(s) 266
Bsh1236I CGCG 1 cut(s) 132
BshFI GGCC 2 cut(s) 448, 719
BshNI GGYRCC 1 cut(s) 18
BsiHKCI CYCGRG 1 cut(s) 543
BsiSI CCGG 2 cut(s) 39, 63
BslFI GGGAC 3 cut(s) 54, 312, 560
BslI CCNNNNNNNGG 2 cut(s) 39, 653
BsmAI GTCTC 2 cut(s) 469, 660
BsmFI GGGAC 3 cut(s) 54, 312, 560
BsnI GGCC 2 cut(s) 448, 719
BsoBI CYCGRG 1 cut(s) 543
Bsp1286I GDGCHC 2 cut(s) 23, 700
Bsp1407I TGTACA 1 cut(s) 497
Bsp143I GATC 1 cut(s) 172
BspACI CCGC 2 cut(s) 228, 249
BspANI GGCC 2 cut(s) 448, 719
BspCNI CTCAG 2 cut(s) 109, 331
BspFNI CGCG 1 cut(s) 132
BspLI GGNNCC 2 cut(s) 20, 70
BspMAI CTGCAG 1 cut(s) 577
BspT107I GGYRCC 1 cut(s) 18
BsrGI TGTACA 1 cut(s) 497
BsrI ACTGG 2 cut(s) 112, 385
BssECI CCNNGG 2 cut(s) 61, 460
BssHII GCGCGC 1 cut(s) 130
BssMI GATC 1 cut(s) 172
BssSI CACGAG 1 cut(s) 739
BssT1I CCWWGG 1 cut(s) 460
Bst2BI CACGAG 1 cut(s) 739
Bst2UI CCWGG 1 cut(s) 163
Bst4CI ACNGT 3 cut(s) 197, 260, 568
Bst6I CTCTTC 2 cut(s) 176, 315
BstAPI GCANNNNNTGC 1 cut(s) 605
BstAUI TGTACA 1 cut(s) 497
BstC8I GCNNGC 3 cut(s) 128, 132, 249
BstDEI CTNAG 2 cut(s) 96, 339
BstENI CCTNNNNNAGG 1 cut(s) 651
BstF5I GGATG 2 cut(s) 541, 610
BstFNI CGCG 1 cut(s) 132
BstHHI GCGC 2 cut(s) 132, 134
BstKTI GATC 1 cut(s) 175
BstMAI GTCTC 2 cut(s) 469, 660
BstMBI GATC 1 cut(s) 172
BstMWI GCNNNNNNNGC 4 cut(s) 57, 140, 578, 605
BstNI CCWGG 1 cut(s) 163
BstNSI RCATGY 1 cut(s) 130
BstSCI CCNGG 3 cut(s) 38, 61, 161
BstSFI CTRYAG 1 cut(s) 573
BstSLI GKGCMC 1 cut(s) 23
BstUI CGCG 1 cut(s) 132
BstV1I GCAGC 1 cut(s) 559
BsuI GTATCC 1 cut(s) 104
BsuRI GGCC 2 cut(s) 448, 719
BtgZI GCGATG 1 cut(s) 13
BtsCI GGATG 2 cut(s) 541, 610
BtsI GCAGTG 1 cut(s) 582
BtsIMutI CAGTG 3 cut(s) 105, 202, 582
Cac8I GCNNGC 3 cut(s) 128, 132, 249
CaiI CAGNNNCTG 1 cut(s) 581
CfoI GCGC 2 cut(s) 132, 134
Cfr13I GGNCC 4 cut(s) 68, 400, 464, 718
Csp6I GTAC 5 cut(s) 55, 88, 231, 498, 525
CviAII CATG 5 cut(s) 127, 238, 344, 631, 670
CviQI GTAC 5 cut(s) 55, 88, 231, 498, 525
DdeI CTNAG 2 cut(s) 96, 339
DpnI GATC 1 cut(s) 174
DpnII GATC 1 cut(s) 172
Eam1104I CTCTTC 2 cut(s) 176, 315
EarI CTCTTC 2 cut(s) 176, 315
Eco130I CCWWGG 1 cut(s) 460
Eco24I GRGCYC 1 cut(s) 700
Eco47I GGWCC 3 cut(s) 68, 400, 464
Eco57I CTGAAG 1 cut(s) 200
Eco88I CYCGRG 1 cut(s) 543
EcoNI CCTNNNNNAGG 1 cut(s) 651
EcoRII CCWGG 1 cut(s) 161
EcoT14I CCWWGG 1 cut(s) 460
EcoT38I GRGCYC 1 cut(s) 700
ErhI CCWWGG 1 cut(s) 460
FaeI CATG 5 cut(s) 130, 241, 347, 634, 673
FaqI GGGAC 3 cut(s) 54, 312, 560
FatI CATG 5 cut(s) 126, 237, 343, 630, 669
FauI CCCGC 1 cut(s) 256
FauNDI CATATG 2 cut(s) 156, 529
FblI GTMKAC 1 cut(s) 201
Fnu4HI GCNGC 1 cut(s) 573
FokI GGATG 2 cut(s) 548, 617
FriOI GRGCYC 1 cut(s) 700
Fsp4HI GCNGC 1 cut(s) 573
FspBI CTAG 3 cut(s) 123, 167, 506
GlaI GCGC 2 cut(s) 131, 133
GluI GCNGC 1 cut(s) 573
GsuI CTGGAG 1 cut(s) 463
HaeIII GGCC 2 cut(s) 448, 719
HapII CCGG 2 cut(s) 39, 63
HhaI GCGC 2 cut(s) 132, 134
Hin1II CATG 5 cut(s) 130, 241, 347, 634, 673
Hin6I GCGC 2 cut(s) 130, 132
HinP1I GCGC 2 cut(s) 130, 132
HincII GTYRAC 1 cut(s) 412
HindII GTYRAC 1 cut(s) 412
HinfI GANTC 1 cut(s) 74
HpaI GTTAAC 1 cut(s) 412
HpaII CCGG 2 cut(s) 39, 63
Hpy166II GTNNAC 3 cut(s) 55, 202, 412
Hpy188I TCNGA 4 cut(s) 79, 340, 522, 709
Hpy188III TCNNGA 5 cut(s) 71, 403, 545, 682, 741
Hpy8I GTNNAC 3 cut(s) 55, 202, 412
HpyAV CCTTC 1 cut(s) 653
HpyCH4III ACNGT 3 cut(s) 197, 260, 568
HpyCH4V TGCA 3 cut(s) 283, 575, 626
HpyF10VI GCNNNNNNNGC 4 cut(s) 57, 140, 578, 605
HpyF3I CTNAG 2 cut(s) 96, 339
Hsp92II CATG 5 cut(s) 130, 241, 347, 634, 673
HspAI GCGC 2 cut(s) 130, 132
KspAI GTTAAC 1 cut(s) 412
Kzo9I GATC 1 cut(s) 172
Lsp1109I GCAGC 1 cut(s) 559
LweI GCATC 3 cut(s) 277, 595, 624
MaeI CTAG 3 cut(s) 123, 167, 506
MaeIII GTNAC 2 cut(s) 191, 425
MalI GATC 1 cut(s) 174
MboI GATC 1 cut(s) 172
MboII GAAGA 3 cut(s) 182, 193, 332
MhlI GDGCHC 2 cut(s) 23, 700
MluCI AATT 6 cut(s) 135, 356, 360, 510, 676, 725
MnlI CCTC 7 cut(s) 21, 316, 438, 477, 526, 551, 711
MseI TTAA 5 cut(s) 221, 359, 411, 615, 729
MslI CAYNNNNRTG 1 cut(s) 221
MspA1I CMGCKG 1 cut(s) 178
MspI CCGG 2 cut(s) 39, 63
MspR9I CCNGG 3 cut(s) 40, 63, 163
MvaI CCWGG 1 cut(s) 163
MvnI CGCG 1 cut(s) 132
MwoI GCNNNNNNNGC 4 cut(s) 57, 140, 578, 605
NciI CCSGG 2 cut(s) 40, 63
NdeI CATATG 2 cut(s) 156, 529
NdeII GATC 1 cut(s) 172
NlaIII CATG 5 cut(s) 130, 241, 347, 634, 673
NlaIV GGNNCC 2 cut(s) 20, 70
NmuCI GTSAC 1 cut(s) 191
NspI RCATGY 1 cut(s) 130
PaeI GCATGC 1 cut(s) 130
PauI GCGCGC 1 cut(s) 130
PfeI GAWTC 1 cut(s) 74
PflFI GACNNNGTC 1 cut(s) 206
PkrI GCNGC 1 cut(s) 574
PshBI ATTAAT 1 cut(s) 359
Psp6I CCWGG 1 cut(s) 161
PspGI CCWGG 1 cut(s) 161
PspN4I GGNNCC 2 cut(s) 20, 70
PspPI GGNCC 4 cut(s) 68, 400, 464, 718
PstI CTGCAG 1 cut(s) 577
PstNI CAGNNNCTG 1 cut(s) 581
PsyI GACNNNGTC 1 cut(s) 206
PteI GCGCGC 1 cut(s) 130
PvuII CAGCTG 1 cut(s) 178
RsaI GTAC 5 cut(s) 56, 89, 232, 499, 526
RsaNI GTAC 5 cut(s) 55, 88, 231, 498, 525
RseI CAYNNNNRTG 1 cut(s) 221
SaqAI TTAA 5 cut(s) 221, 359, 411, 615, 729
SatI GCNGC 1 cut(s) 573
Sau3AI GATC 1 cut(s) 172
Sau96I GGNCC 4 cut(s) 68, 400, 464, 718
ScrFI CCNGG 3 cut(s) 40, 63, 163
SduI GDGCHC 2 cut(s) 23, 700
SetI ASST 9 cut(s) 20, 180, 210, 421, 469, 562, 574, 621, 645
SfaNI GCATC 3 cut(s) 277, 595, 624
SfcI CTRYAG 1 cut(s) 573
SinI GGWCC 3 cut(s) 68, 400, 464
SmiMI CAYNNNNRTG 1 cut(s) 221
SmlI CTYRAG 1 cut(s) 472
SmoI CTYRAG 1 cut(s) 472
SphI GCATGC 1 cut(s) 130
Sse9I AATT 6 cut(s) 135, 356, 360, 510, 676, 725
SsiI CCGC 2 cut(s) 228, 249
SspI AATATT 1 cut(s) 46
SspMI CTAG 3 cut(s) 123, 167, 506
StyD4I CCNGG 3 cut(s) 38, 61, 161
StyI CCWWGG 1 cut(s) 460
TaaI ACNGT 3 cut(s) 197, 260, 568
TaqI TCGA 2 cut(s) 5, 210
TaqII GACCGA 1 cut(s) 388
TasI AATT 6 cut(s) 135, 356, 360, 510, 676, 725
TatI WGTACW 4 cut(s) 54, 87, 497, 524
TfiI GAWTC 1 cut(s) 74
Tru1I TTAA 5 cut(s) 221, 359, 411, 615, 729
Tru9I TTAA 5 cut(s) 221, 359, 411, 615, 729
TscAI CASTG 3 cut(s) 112, 202, 582
TseFI GTSAC 1 cut(s) 191
TseI GCWGC 1 cut(s) 572
Tsp45I GTSAC 1 cut(s) 191
TspDTI ATGAA 3 cut(s) 205, 226, 379
TspRI CASTG 3 cut(s) 112, 202, 582
Tth111I GACNNNGTC 1 cut(s) 206
VpaK11BI GGWCC 3 cut(s) 68, 400, 464
VspI ATTAAT 1 cut(s) 359
XagI CCTNNNNNAGG 1 cut(s) 651
XapI RAATTY 2 cut(s) 676, 725
XceI RCATGY 1 cut(s) 130
XmiI GTMKAC 1 cut(s) 201
XspI CTAG 3 cut(s) 123, 167, 506
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.