pycom06g13990

Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
pyrus_communis
Chr6
OG0001670
Physical Location & Seq
Forward (+)
18882619 .. 18884240
1622 bp
Loading structure...
UTR
Exon/CDS
Intron
pycom06g13990.1

Sequence Viewer

Length: 921 bp
ATGCACGCAATTCGCGCAAGATATTATTTGAAGGAATTGGTGTTAAAAATTGGATTAGTGAAGTTAATTAGATACAACCCACATGGCCAGGCTAGAAGCAGGATAGATCAGCTGAAGAGATTGGGTCACAGTGTAGACAAGGTTTGGCCTGTTCTATGTTTAGAGCTTAAAGAATTTATTTTCGGGTTTGCAGATTTCCATGATAGAGTTGAGTTCATCTTAATGGGCGGTACTTTGATGTCGTTGCCCGTAGATTACCGTGATTACTTTATTAGAAATCTGCACGATGCATTATCGGGACACACTTCTGCCAATGTTGAAGAGGCAGTTGCCTGCTCTGAGCATGGTGCTACTAAATGTATTGGAATGACCATTGAATCGCCAGATTATTGCCTTGGACCTCACTTGAGACAAATGCTTTCTTATGGTTGTACAAGACTAGAAATTGGAGTTCAGAGTACATACGAGGATGTGGCTCGGGACACCAATAGAGGTCATACCGTAGCTGCAGTGGCTGATTGTTTTTGGTTGGCAAAGGATGCTGGTTTTAAGGTGGTTGTACACATGATGCCTGATCTTCCAAATGTAGGCGTGGTGAGAGACATGGAGAGTTTTCGGGAGTTCTTTGAGACCCCCTCGTTCAGAGCAGATGGGCTTAAAATTTATCCAACATTCGTGATCCGTGGAACTGGACTCTATGAGCTTTGGAAAACGGGCAGGTATAGAAATTACCCACCTGAGCAACTTGTGGACATTCTTACTGGTTCTAGGACATACATCACAAAATTAGGCCAGACCAAGTGGAGCTTGTTCGTCGTGATTATATGGCAAATGAAGGATGGGAAACATTTCTTTCATATGAAGATACTTGCCTGGTATTCGTTCTTTATATGTGAGAGAGTGCTTCGTCAAACGAAATGA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
GO:0000228 GO:0000785 GO:0000790 GO:0000791 GO:0002097 GO:0002098 GO:0003674 GO:0003824 GO:0004402 GO:0005575 GO:0005622 GO:0005623 GO:0005634 GO:0005694 GO:0005719 GO:0005737 GO:0005829 GO:0006139 GO:0006325 GO:0006355 GO:0006357 GO:0006396 GO:0006399 GO:0006400 GO:0006464 GO:0006473 GO:0006475 GO:0006725 GO:0006807 GO:0006996 GO:0007275 GO:0007389 GO:0008033 GO:0008080 GO:0008150 GO:0008152 GO:0008283 GO:0009292 GO:0009294 GO:0009451 GO:0009653 GO:0009798 GO:0009889 GO:0009966 GO:0009987 GO:0010467 GO:0010468 GO:0010556 GO:0010646 GO:0010928 GO:0016043 GO:0016070 GO:0016407 GO:0016410 GO:0016569 GO:0016570 GO:0016573 GO:0016740 GO:0016746 GO:0016747 GO:0018193 GO:0018205 GO:0018393 GO:0018394 GO:0019219 GO:0019222 GO:0019538 GO:0022603 GO:0023051 GO:0031323 GO:0031326 GO:0031974 GO:0031981 GO:0032501 GO:0032502 GO:0032991 GO:0033588 GO:0034212 GO:0034470 GO:0034641 GO:0034660 GO:0035265 GO:0036211 GO:0040007 GO:0043170 GO:0043226 GO:0043227 GO:0043228 GO:0043229 GO:0043231 GO:0043232 GO:0043233 GO:0043412 GO:0043543 GO:0044237 GO:0044238 GO:0044260 GO:0044267 GO:0044422 GO:0044424 GO:0044427 GO:0044428 GO:0044444 GO:0044446 GO:0044454 GO:0044464 GO:0044764 GO:0046483 GO:0048583 GO:0048589 GO:0048731 GO:0048831 GO:0048856 GO:0050789 GO:0050793 GO:0050794 GO:0051171 GO:0051239 GO:0051252 GO:0051276 GO:0051704 GO:0060255 GO:0061733 GO:0065001 GO:0065007 GO:0070013 GO:0071704 GO:0071840 GO:0080090 GO:0090304 GO:0090708 GO:0099402 GO:1900618 GO:1901360 GO:1901371 GO:1901564 GO:1903506 GO:1905392 GO:1905421 GO:1905428 GO:2000024 GO:2000025 GO:2000026 GO:2000112 GO:2001141
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
Acetyltransf_1 Radical_SAM Radical_SAM_C

Protein Analysis

307

Amino Acids

35.38

Weight (kDa)

8.86

Isoelectric Point (pI)

28.24

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
Radical_SAM PF04055 117 - 196 8e-10 Radical SAM superfamily
Radical_SAM_C PF16199 217 - 254 1.2e-09 Radical_SAM C-terminal domain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

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Publication-ready
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
Acc36I ACCTGC 1 cut(s) 708
AccI GTMKAC 1 cut(s) 135
AccII CGCG 1 cut(s) 15
AciI CCGC 1 cut(s) 228
AclWI GGATC 1 cut(s) 673
AcoI YGGCCR 1 cut(s) 85
AcsI RAATTY 2 cut(s) 173, 660
AcuI CTGAAG 1 cut(s) 134
AfaI GTAC 4 cut(s) 232, 433, 460, 561
AfiI CCNNNNNNNGG 1 cut(s) 587
AgsI TTSAA 3 cut(s) 31, 320, 377
AjnI CCWGG 2 cut(s) 87, 872
AluBI AGCT 5 cut(s) 112, 166, 506, 703, 807
AluI AGCT 5 cut(s) 112, 166, 506, 703, 807
Alw26I GTCTC 3 cut(s) 403, 594, 623
AlwI GGATC 1 cut(s) 673
AlwNI CAGNNNCTG 1 cut(s) 515
Ama87I CYCGRG 1 cut(s) 477
AoxI GGCC 3 cut(s) 85, 146, 790
ApeKI GCWGC 1 cut(s) 506
ApoI RAATTY 2 cut(s) 173, 660
Asp700I GAANNNNTTC 1 cut(s) 848
AspLEI GCGC 1 cut(s) 17
AspS9I GGNCC 1 cut(s) 398
AsuHPI GGTGA 1 cut(s) 607
AvaI CYCGRG 1 cut(s) 477
AvaII GGWCC 1 cut(s) 398
BalI TGGCCA 1 cut(s) 87
BbvI GCAGC 1 cut(s) 493
BccI CCATC 2 cut(s) 644, 833
BcgI CGANNNNNNTGC 1 cut(s) 27
BciT130I CCWGG 2 cut(s) 89, 874
BcoDI GTCTC 3 cut(s) 403, 594, 623
BfaI CTAG 3 cut(s) 93, 440, 768
BfmI CTRYAG 1 cut(s) 507
BfuAI ACCTGC 1 cut(s) 708
BisI GCNGC 1 cut(s) 507
BlsI GCNGC 1 cut(s) 508
Bme1390I CCNGG 2 cut(s) 89, 874
Bme18I GGWCC 1 cut(s) 398
BmeT110I CYCGRG 1 cut(s) 477
BmgT120I GGNCC 1 cut(s) 398
BmrFI CCNGG 2 cut(s) 89, 874
BmsI GCATC 3 cut(s) 277, 529, 558
BplI GAGNNNNNCTC 2 cut(s) 620, 652
Bpu10I CCTNAGC 1 cut(s) 738
BpuEI CTTGAG 1 cut(s) 427
BsaI GGTCTC 1 cut(s) 623
BsaJI CCNNGG 2 cut(s) 394, 682
Bsc4I CCNNNNNNNGG 1 cut(s) 587
Bse1I ACTGG 2 cut(s) 694, 766
BseBI CCWGG 2 cut(s) 89, 874
BseDI CCNNGG 2 cut(s) 394, 682
BseGI GGATG 3 cut(s) 475, 544, 844
BseLI CCNNNNNNNGG 1 cut(s) 587
BseMII CTCAG 2 cut(s) 330, 729
BseNI ACTGG 2 cut(s) 694, 766
BseXI GCAGC 1 cut(s) 493
BsgI GTGCAG 1 cut(s) 266
Bsh1236I CGCG 1 cut(s) 15
BshFI GGCC 3 cut(s) 87, 148, 792
BsiHKCI CYCGRG 1 cut(s) 477
BslFI GGGAC 2 cut(s) 312, 494
BslI CCNNNNNNNGG 1 cut(s) 587
BsmAI GTCTC 3 cut(s) 403, 594, 623
BsmFI GGGAC 2 cut(s) 312, 494
BsnI GGCC 3 cut(s) 87, 148, 792
Bso31I GGTCTC 1 cut(s) 623
BsoBI CYCGRG 1 cut(s) 477
Bsp1407I TGTACA 2 cut(s) 431, 559
Bsp143I GATC 3 cut(s) 106, 574, 678
BspACI CCGC 1 cut(s) 228
BspANI GGCC 3 cut(s) 87, 148, 792
BspCNI CTCAG 2 cut(s) 331, 730
BspFNI CGCG 1 cut(s) 15
BspMAI CTGCAG 1 cut(s) 511
BspMI ACCTGC 1 cut(s) 708
BspPI GGATC 1 cut(s) 673
BspTNI GGTCTC 1 cut(s) 623
BsrGI TGTACA 2 cut(s) 431, 559
BsrI ACTGG 2 cut(s) 694, 766
BssECI CCNNGG 2 cut(s) 394, 682
BssMI GATC 3 cut(s) 106, 574, 678
BssT1I CCWWGG 1 cut(s) 394
Bst2UI CCWGG 2 cut(s) 89, 874
Bst4CI ACNGT 3 cut(s) 131, 260, 502
Bst6I CTCTTC 2 cut(s) 110, 315
BstAPI GCANNNNNTGC 1 cut(s) 539
BstAUI TGTACA 2 cut(s) 431, 559
BstC8I GCNNGC 2 cut(s) 6, 334
BstDEI CTNAG 2 cut(s) 339, 738
BstDSI CCRYGG 1 cut(s) 682
BstF5I GGATG 3 cut(s) 475, 544, 844
BstFNI CGCG 1 cut(s) 15
BstHHI GCGC 1 cut(s) 17
BstKTI GATC 3 cut(s) 109, 577, 681
BstMAI GTCTC 3 cut(s) 403, 594, 623
BstMBI GATC 3 cut(s) 106, 574, 678
BstMWI GCNNNNNNNGC 3 cut(s) 14, 512, 539
BstNI CCWGG 2 cut(s) 89, 874
BstSCI CCNGG 2 cut(s) 87, 872
BstSFI CTRYAG 1 cut(s) 507
BstUI CGCG 1 cut(s) 15
BstV1I GCAGC 1 cut(s) 493
BsuRI GGCC 3 cut(s) 87, 148, 792
BtgI CCRYGG 1 cut(s) 682
BtsCI GGATG 3 cut(s) 475, 544, 844
BtsI GCAGTG 1 cut(s) 516
BtsIMutI CAGTG 2 cut(s) 136, 516
BveI ACCTGC 1 cut(s) 708
Cac8I GCNNGC 2 cut(s) 6, 334
CaiI CAGNNNCTG 1 cut(s) 515
CfoI GCGC 1 cut(s) 17
Cfr13I GGNCC 1 cut(s) 398
Csp6I GTAC 4 cut(s) 231, 432, 459, 560
CviAII CATG 5 cut(s) 83, 200, 344, 565, 604
CviQI GTAC 4 cut(s) 231, 432, 459, 560
DdeI CTNAG 2 cut(s) 339, 738
DpnI GATC 3 cut(s) 108, 576, 680
DpnII GATC 3 cut(s) 106, 574, 678
EaeI YGGCCR 1 cut(s) 85
Eam1104I CTCTTC 2 cut(s) 110, 315
EarI CTCTTC 2 cut(s) 110, 315
Eco130I CCWWGG 1 cut(s) 394
Eco31I GGTCTC 1 cut(s) 623
Eco47I GGWCC 1 cut(s) 398
Eco57I CTGAAG 1 cut(s) 134
Eco88I CYCGRG 1 cut(s) 477
EcoRII CCWGG 2 cut(s) 87, 872
EcoT14I CCWWGG 1 cut(s) 394
EcoT22I ATGCAT 1 cut(s) 292
ErhI CCWWGG 1 cut(s) 394
FaeI CATG 5 cut(s) 86, 203, 347, 568, 607
FalI AAGNNNNNCTT 2 cut(s) 791, 823
FaqI GGGAC 2 cut(s) 312, 494
FatI CATG 5 cut(s) 82, 199, 343, 564, 603
FauNDI CATATG 1 cut(s) 858
FblI GTMKAC 1 cut(s) 135
Fnu4HI GCNGC 1 cut(s) 507
FokI GGATG 3 cut(s) 482, 551, 851
Fsp4HI GCNGC 1 cut(s) 507
FspBI CTAG 3 cut(s) 93, 440, 768
GlaI GCGC 1 cut(s) 16
GluI GCNGC 1 cut(s) 507
HaeIII GGCC 3 cut(s) 87, 148, 792
HhaI GCGC 1 cut(s) 17
Hin1II CATG 5 cut(s) 86, 203, 347, 568, 607
Hin6I GCGC 1 cut(s) 15
HinP1I GCGC 1 cut(s) 15
HinfI GANTC 2 cut(s) 377, 693
HphI GGTGA 1 cut(s) 607
Hpy166II GTNNAC 3 cut(s) 136, 562, 751
Hpy188I TCNGA 3 cut(s) 340, 456, 644
Hpy188III TCNNGA 5 cut(s) 297, 479, 617, 676, 817
Hpy8I GTNNAC 3 cut(s) 136, 562, 751
Hpy99I CGWCG 1 cut(s) 818
HpyAV CCTTC 2 cut(s) 25, 829
HpyCH4III ACNGT 3 cut(s) 131, 260, 502
HpyCH4V TGCA 5 cut(s) 4, 191, 283, 290, 509
HpyF10VI GCNNNNNNNGC 3 cut(s) 14, 512, 539
HpyF3I CTNAG 2 cut(s) 339, 738
Hsp92II CATG 5 cut(s) 86, 203, 347, 568, 607
HspAI GCGC 1 cut(s) 15
Kzo9I GATC 3 cut(s) 106, 574, 678
LmnI GCTCC 1 cut(s) 804
Lsp1109I GCAGC 1 cut(s) 493
LweI GCATC 3 cut(s) 277, 529, 558
MaeI CTAG 3 cut(s) 93, 440, 768
MaeIII GTNAC 1 cut(s) 125
MalI GATC 3 cut(s) 108, 576, 680
MboI GATC 3 cut(s) 106, 574, 678
MboII GAAGA 4 cut(s) 127, 332, 569, 874
MlsI TGGCCA 1 cut(s) 87
MluCI AATT 9 cut(s) 9, 35, 48, 66, 173, 444, 660, 727, 785
MluNI TGGCCA 1 cut(s) 87
MlyI GAGTC 1 cut(s) 687
MmeI TCCRAC 1 cut(s) 692
MnlI CCTC 5 cut(s) 316, 411, 460, 485, 646
Mox20I TGGCCA 1 cut(s) 87
Mph1103I ATGCAT 1 cut(s) 292
MroXI GAANNNNTTC 1 cut(s) 848
MscI TGGCCA 1 cut(s) 87
MseI TTAA 6 cut(s) 44, 65, 168, 221, 549, 657
MslI CAYNNNNRTG 1 cut(s) 221
Msp20I TGGCCA 1 cut(s) 87
MspA1I CMGCKG 1 cut(s) 112
MspR9I CCNGG 2 cut(s) 89, 874
MvaI CCWGG 2 cut(s) 89, 874
MvnI CGCG 1 cut(s) 15
MwoI GCNNNNNNNGC 3 cut(s) 14, 512, 539
NdeI CATATG 1 cut(s) 858
NdeII GATC 3 cut(s) 106, 574, 678
NlaIII CATG 5 cut(s) 86, 203, 347, 568, 607
NmuCI GTSAC 1 cut(s) 125
NsiI ATGCAT 1 cut(s) 292
PdmI GAANNNNTTC 1 cut(s) 848
PfeI GAWTC 1 cut(s) 377
PkrI GCNGC 1 cut(s) 508
PleI GAGTC 1 cut(s) 687
PpsI GAGTC 1 cut(s) 687
Psp6I CCWGG 2 cut(s) 87, 872
PspGI CCWGG 2 cut(s) 87, 872
PspPI GGNCC 1 cut(s) 398
PstI CTGCAG 1 cut(s) 511
PstNI CAGNNNCTG 1 cut(s) 515
PvuII CAGCTG 1 cut(s) 112
RsaI GTAC 4 cut(s) 232, 433, 460, 561
RsaNI GTAC 4 cut(s) 231, 432, 459, 560
RseI CAYNNNNRTG 1 cut(s) 221
SaqAI TTAA 6 cut(s) 44, 65, 168, 221, 549, 657
SatI GCNGC 1 cut(s) 507
Sau3AI GATC 3 cut(s) 106, 574, 678
Sau96I GGNCC 1 cut(s) 398
SchI GAGTC 1 cut(s) 687
ScrFI CCNGG 2 cut(s) 89, 874
SfaNI GCATC 3 cut(s) 277, 529, 558
SfcI CTRYAG 1 cut(s) 507
SinI GGWCC 1 cut(s) 398
SmiMI CAYNNNNRTG 1 cut(s) 221
SmlI CTYRAG 1 cut(s) 406
SmoI CTYRAG 1 cut(s) 406
Sse9I AATT 9 cut(s) 9, 35, 48, 66, 173, 444, 660, 727, 785
SsiI CCGC 1 cut(s) 228
SspMI CTAG 3 cut(s) 93, 440, 768
StyD4I CCNGG 2 cut(s) 87, 872
StyI CCWWGG 1 cut(s) 394
TaaI ACNGT 3 cut(s) 131, 260, 502
TasI AATT 9 cut(s) 9, 35, 48, 66, 173, 444, 660, 727, 785
TatI WGTACW 3 cut(s) 431, 458, 559
TfiI GAWTC 1 cut(s) 377
Tru1I TTAA 6 cut(s) 44, 65, 168, 221, 549, 657
Tru9I TTAA 6 cut(s) 44, 65, 168, 221, 549, 657
TscAI CASTG 2 cut(s) 136, 516
TseFI GTSAC 1 cut(s) 125
TseI GCWGC 1 cut(s) 506
Tsp45I GTSAC 1 cut(s) 125
TspDTI ATGAA 4 cut(s) 205, 845, 848, 875
TspGWI ACGGA 1 cut(s) 671
TspRI CASTG 2 cut(s) 136, 516
VpaK11BI GGWCC 1 cut(s) 398
XapI RAATTY 2 cut(s) 173, 660
XmiI GTMKAC 1 cut(s) 135
XmnI GAANNNNTTC 1 cut(s) 848
XspI CTAG 3 cut(s) 93, 440, 768
Zsp2I ATGCAT 1 cut(s) 292
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.