Rw4G018840

Cytochrome p450

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
rosa_wichuraiana
Chr4
OG0000354
Physical Location & Seq
Reverse (-)
41644290 .. 41647529
3240 bp
Loading structure...
UTR
Exon/CDS
Intron
Rw4G018840.1

Sequence Viewer

Length: 1542 bp
ATGGCTGACAAGACCCTCCTACTAGTCTTATGGATTCCATTTCTTCTCTTGCTCCCTTTACTACTGCTTTTACTGAGAACGCAGATCAATAAGCCACAAAAGCACTTCCCACCAAGCCCTCCTAAGCTTCCCATTATAGGCAACCTCCACCAGTTTACTCAATCTGGTTCATCACTTCATCAAAACCTATGGAGACTATCACAAAAATACGGACCACTCATGCTCTTACACATGGGTCGCAGACCGACCCTCATAATCTCATCAGCTGAAGCAGCAAAACAGACCTTGAAAGATAATGATCTCCACTGTTGCAGCAGACCGGCCTCCTCGGGATCTCGCAGACTCACATTTAACTATCTAGACATAGGATTTGCGCCTTACGATGAATATTGGCGAGAGATAAGAAAGATATGTGTGCTTGAGATTTTCAGTGCCAAAAGGGTTCAGTCGTATAGGTCTATTAGAGAAGAAGAAGTCGTGAAGATGATTGATTCAATCTCTGACGCATCAGCTTCATCTTCTCCTGTTAACCTTACTGAGAAGTTGTTTGCTCTCATGGGCAGCATAATTTTCAGGATTGTTTTCGGGATAAGTTTCCAAGGGAGCAATTTGGAGCATGAAAGATTTCTTCGAGTGCTTCATGATAGTCGAGATATGGTTACAGGCTTCTCATCATGCGCAGCTGATTTCTTTCCTCCATGTATAGGGTGGATCATAGACAGGATCTCCGGTAAACATAGAGAGTTTGACAGAGTTTCCAGGGAAGTTCATCGCTTTTTTCAGCAGGCGATTGATGATCATCTCAGGCCTGGGAGGACACAACAGGAGCATGAAGATATAGTTGATGTGCTGCTTAAAATGGTCAAGAAGCAAACTGGGATTGGAGCTGCTCAGCTTGGTCATAATAACATCAAGGCAGTTCTCTTGGATTTGTTTATAGGAGGAGTAGACTCCCCTGCAACTGTCATGGTTTGGGCAATGGCAGAGCTAGCTACGAATACAAGAGTGATGAAGAAAGCACAGGAAGAAATTAGAAACTGTATTGGCAATAAAGGAAAAGCCACTGAAATTGATACAGAGCAGCTGCAGTACCTCAAGATGATAGTGAAAGAAACACTTCGACTACATCCACCAGGTCCCCTACTTCTTCCAAGAGAAACCATGTCCCACTTCAAAGTCCTTAGCTATGATGTTGACCCCAAAACAACAATTCTCGTTAATGATTGGGCAATCTCACGAGATCCAAAATTTTGGAACGACCCAGAAAAGTTCATTCCGGAAAGATTTGATGATAGTTCTGTTGATTTTAAAGGGCAACACTTTGACTTCTTGCCGTTTGGAGCTGGTCGAAGAATCTGTCCAGGGATTTATATGGCAACGACGACAATGGAGCTTGTACTTGCCGAATTGTTGTGCTGCTTTGATTGGAAAGTGCCTGATGGAATGAATGAGGAAGATATGAAGATGGAAGAAACAACCCATGGGGCAGTTATTTCCTTAAAAAATCCTCTCAATCTTGTCCCTATGAGATATTCTTGTTAG
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
p450

Protein Analysis

513

Amino Acids

58.53

Weight (kDa)

7.99

Isoelectric Point (pI)

46.42

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
p450 PF00067 37 - 491 1e-99 Cytochrome P450
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Orthologous Genes (Group: OG0000354)

Species Orthologous Gene IDs
arabidopsis_thaliana AT1G13080 AT1G13080 AT1G13090 AT1G13090 AT1G13100 AT1G13110 AT2G02580 AT2G24180 AT3G26150 AT3G26160 AT3G26170 AT3G26180 AT3G26180 AT3G26190 AT3G26200 AT3G26210 AT3G26290 AT3G26290 AT3G26300 AT3G26310 AT3G26320 AT3G26330 AT3G26830 AT3G44250 AT3G53280 AT3G53290 AT3G53300 AT3G53305 AT5G25120 AT5G25130 AT5G25140 AT5G25180 AT5G35715 AT5G57260
fragaria_vesca FvH4_4g25390 FvH4_4g25390 FvH4_4g25390
malus_domestica MD13G1103500.v1.1 MD13G1103800.v1.1 MD13G1104100.v1.1 MD16G1103600.v1.1 MD16G1104000.v1.1 MD16G1104200.v1.1 MD16G1104300.v1.1
prunus_persica Prupe.1G170800_v2.0.a1 Prupe.1G242300_v2.0.a1 Prupe.1G242400_v2.0.a1
pyrus_communis pycom13g09040 pycom16g08850 pycom16g08860
rosa_chinensis RchiOBHm_Chr4g0419321 RchiOBHm_Chr4g0419411 RchiOBHm_Chr4g0419461 RchiOBHm_Chr4g0419481 RchiOBHm_Chr4g0419491 RchiOBHm_Chr4g0419571 RchiOBHm_Chr4g0432681 RchiOBHm_Chr4g0432701 RchiOBHm_Chr5g0025811
rosa_laevigata RLG00000003494 RLG00000006819 RLG00000006820 RLG00000006821 RLG00000006823 RLG00000007814 RLG00000007815 RLG00000032878
rosa_multiflora Rmu_co8315439.1_g000001 Rmu_sc0000455.1_g000013 Rmu_sc0000455.1_g000035 Rmu_sc0000455.1_g000058 Rmu_sc0000675.1_g000043 Rmu_sc0001912.1_g000035 Rmu_sc0002401.1_g000014 Rmu_sc0004932.1_g000013 Rmu_sc0008245.1_g000007 Rmu_sc0009481.1_g000005 Rmu_ssc0000467.1_g000029
rosa_roxburghii Rroxscaffold_1G00053390 Rroxscaffold_1G00054350 Rroxscaffold_4G00324380 Rroxscaffold_5G00362300 Rroxscaffold_5G00362360 Rroxscaffold_5G00374140 Rroxscaffold_5G00374160
rosa_rugosa Rorug04G0158300 Rorug04G0261600 Rorug04G0261700 Rorug04G0261800
rosa_samantha Rh4AG220300 Rh4AG316100 Rh4BG221600 Rh4BG222000 Rh4BG222100 Rh4BG222200 Rh4BG324100 Rh4CG233000 Rh4CG233100 Rh4CG233200 Rh4CG233900 Rh4CG339100 Rh4DG319500
rosa_wichuraiana Rw4G018840 Rw4G018880 Rw4G018900 Rw4G018930 Rw4G027500

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
Acc16I TGCGCA 1 cut(s) 679
AccI GTMKAC 1 cut(s) 948
AccIII TCCGGA 1 cut(s) 1276
AclWI GGATC 4 cut(s) 340, 719, 731, 1235
AcsI RAATTY 1 cut(s) 1247
AcuI CTGAAG 1 cut(s) 288
AfaI GTAC 2 cut(s) 1091, 1398
AfiI CCNNNNNNNGG 2 cut(s) 137, 704
AgsI TTSAA 3 cut(s) 289, 495, 1174
AhlI ACTAGT 1 cut(s) 22
AjnI CCWGG 4 cut(s) 758, 808, 1132, 1360
Alw26I GTCTC 1 cut(s) 187
AlwI GGATC 4 cut(s) 340, 719, 731, 1235
Ama87I CYCGRG 1 cut(s) 328
Aor13HI TCCGGA 1 cut(s) 1276
AoxI GGCC 2 cut(s) 321, 806
ApeKI GCWGC 9 cut(s) 272, 312, 561, 680, 850, 887, 1081, 1084, 1416
ApoI RAATTY 1 cut(s) 1247
ArsI GACNNNNNNTTYG 4 cut(s) 353, 385, 1342, 1374
Asp700I GAANNNNTTC 2 cut(s) 624, 1116
AspLEI GCGC 2 cut(s) 376, 680
AspS9I GGNCC 2 cut(s) 212, 1136
AsuNHI GCTAGC 1 cut(s) 988
AvaI CYCGRG 1 cut(s) 328
AvaII GGWCC 2 cut(s) 212, 1136
BauI CACGAG 1 cut(s) 1236
BbvI GCAGC 9 cut(s) 284, 324, 573, 692, 837, 874, 1071, 1093, 1403
BccI CCATC 2 cut(s) 1433, 1459
BceAI ACGGC 1 cut(s) 1318
BciT130I CCWGG 4 cut(s) 760, 810, 1134, 1362
BclI TGATCA 1 cut(s) 796
BcoDI GTCTC 1 cut(s) 187
BcuI ACTAGT 1 cut(s) 22
BfaI CTAG 3 cut(s) 23, 359, 989
BfmI CTRYAG 1 cut(s) 1085
BisI GCNGC 9 cut(s) 273, 313, 562, 681, 851, 888, 1082, 1085, 1417
BlpI GCTNAGC 1 cut(s) 891
BlsI GCNGC 9 cut(s) 274, 314, 563, 682, 852, 889, 1083, 1086, 1418
Bme1390I CCNGG 4 cut(s) 760, 810, 1134, 1362
Bme18I GGWCC 2 cut(s) 212, 1136
BmeT110I CYCGRG 1 cut(s) 328
BmgT120I GGNCC 2 cut(s) 212, 1136
BmiI GGNNCC 1 cut(s) 1138
BmrFI CCNGG 4 cut(s) 760, 810, 1134, 1362
BmrI ACTGGG 1 cut(s) 885
BmsI GCATC 1 cut(s) 515
BmtI GCTAGC 1 cut(s) 992
BmuI ACTGGG 1 cut(s) 885
Bpu10I CCTNAGC 2 cut(s) 123, 1181
Bpu1102I GCTNAGC 1 cut(s) 891
BpuEI CTTGAG 2 cut(s) 440, 1079
BsaBI GATNNNNATC 2 cut(s) 297, 798
BsaJI CCNNGG 6 cut(s) 327, 598, 759, 809, 1361, 1480
BsaWI WCCGGW 2 cut(s) 728, 1276
BsaXI ACNNNNNCTCC 2 cut(s) 710, 740
Bsc4I CCNNNNNNNGG 2 cut(s) 137, 704
Bse118I RCCGGY 1 cut(s) 319
Bse1I ACTGG 2 cut(s) 151, 880
Bse3DI GCAATG 1 cut(s) 984
Bse8I GATNNNNATC 2 cut(s) 297, 798
BseAI TCCGGA 1 cut(s) 1276
BseBI CCWGG 4 cut(s) 760, 810, 1134, 1362
BseDI CCNNGG 6 cut(s) 327, 598, 759, 809, 1361, 1480
BseGI GGATG 1 cut(s) 1126
BseJI GATNNNNATC 2 cut(s) 297, 798
BseLI CCNNNNNNNGG 2 cut(s) 137, 704
BseMI GCAATG 1 cut(s) 984
BseMII CTCAG 4 cut(s) 65, 528, 817, 905
BseNI ACTGG 2 cut(s) 151, 880
BseRI GAGGAG 2 cut(s) 316, 957
BseXI GCAGC 9 cut(s) 284, 324, 573, 692, 837, 874, 1071, 1093, 1403
BshFI GGCC 2 cut(s) 323, 808
BsiHKCI CYCGRG 1 cut(s) 328
BsiSI CCGG 3 cut(s) 320, 729, 1277
BslFI GGGAC 3 cut(s) 1122, 1150, 1505
BslI CCNNNNNNNGG 2 cut(s) 137, 704
BsmAI GTCTC 1 cut(s) 187
BsmFI GGGAC 3 cut(s) 1122, 1150, 1505
BsnI GGCC 2 cut(s) 323, 808
BsoBI CYCGRG 1 cut(s) 328
Bsp13I TCCGGA 1 cut(s) 1276
Bsp143I GATC 7 cut(s) 84, 298, 332, 711, 723, 796, 1240
Bsp1720I GCTNAGC 1 cut(s) 891
Bsp19I CCATGG 1 cut(s) 1480
BspANI GGCC 2 cut(s) 323, 808
BspCNI CTCAG 4 cut(s) 66, 529, 816, 904
BspEI TCCGGA 1 cut(s) 1276
BspHI TCATGA 1 cut(s) 640
BspLI GGNNCC 1 cut(s) 1138
BspMAI CTGCAG 1 cut(s) 1089
BspOI GCTAGC 1 cut(s) 992
BspPI GGATC 4 cut(s) 340, 719, 731, 1235
BsrDI GCAATG 1 cut(s) 984
BsrFI RCCGGY 1 cut(s) 319
BsrI ACTGG 2 cut(s) 151, 880
BssAI RCCGGY 1 cut(s) 319
BssECI CCNNGG 6 cut(s) 327, 598, 759, 809, 1361, 1480
BssMI GATC 7 cut(s) 84, 298, 332, 711, 723, 796, 1240
BssSI CACGAG 1 cut(s) 1236
BssT1I CCWWGG 2 cut(s) 598, 1480
Bst2BI CACGAG 1 cut(s) 1236
Bst2UI CCWGG 4 cut(s) 760, 810, 1134, 1362
Bst4CI ACNGT 3 cut(s) 308, 964, 1040
BstC8I GCNNGC 2 cut(s) 786, 990
BstDEI CTNAG 6 cut(s) 74, 123, 537, 803, 891, 1181
BstDSI CCRYGG 1 cut(s) 1480
BstF5I GGATG 1 cut(s) 1126
BstHHI GCGC 2 cut(s) 376, 680
BstKTI GATC 7 cut(s) 87, 301, 335, 714, 726, 799, 1243
BstMAI GTCTC 1 cut(s) 187
BstMBI GATC 7 cut(s) 84, 298, 332, 711, 723, 796, 1240
BstMWI GCNNNNNNNGC 3 cut(s) 100, 272, 989
BstNI CCWGG 4 cut(s) 760, 810, 1134, 1362
BstSCI CCNGG 4 cut(s) 758, 808, 1132, 1360
BstSFI CTRYAG 1 cut(s) 1085
BstV1I GCAGC 9 cut(s) 284, 324, 573, 692, 837, 874, 1071, 1093, 1403
BstX2I RGATCY 3 cut(s) 332, 723, 1240
BstXI CCANNNNNNTGG 1 cut(s) 1251
BstYI RGATCY 3 cut(s) 332, 723, 1240
BsuRI GGCC 2 cut(s) 323, 808
BtgI CCRYGG 1 cut(s) 1480
BtgZI GCGATG 1 cut(s) 755
BtsCI GGATG 1 cut(s) 1126
BtsIMutI CAGTG 3 cut(s) 304, 436, 1062
Cac8I GCNNGC 2 cut(s) 786, 990
CciI TCATGA 1 cut(s) 640
CfoI GCGC 2 cut(s) 376, 680
Cfr10I RCCGGY 1 cut(s) 319
Cfr13I GGNCC 2 cut(s) 212, 1136
CseI GACGC 1 cut(s) 512
CsiI ACCWGGT 1 cut(s) 1132
Csp6I GTAC 2 cut(s) 1090, 1397
CspCI CAANNNNNGTGG 2 cut(s) 1051, 1086
CviQI GTAC 2 cut(s) 1090, 1397
DdeI CTNAG 6 cut(s) 74, 123, 537, 803, 891, 1181
DpnI GATC 7 cut(s) 86, 300, 334, 713, 725, 798, 1242
DpnII GATC 7 cut(s) 84, 298, 332, 711, 723, 796, 1240
DraI TTTAAA 1 cut(s) 1309
Eco130I CCWWGG 2 cut(s) 598, 1480
Eco147I AGGCCT 1 cut(s) 808
Eco47I GGWCC 2 cut(s) 212, 1136
Eco57I CTGAAG 1 cut(s) 288
Eco88I CYCGRG 1 cut(s) 328
EcoO109I RGGNCCY 1 cut(s) 1136
EcoRII CCWGG 4 cut(s) 758, 808, 1132, 1360
EcoT14I CCWWGG 2 cut(s) 598, 1480
ErhI CCWWGG 2 cut(s) 598, 1480
FalI AAGNNNNNCTT 2 cut(s) 1101, 1133
FaqI GGGAC 3 cut(s) 1122, 1150, 1505
FbaI TGATCA 1 cut(s) 796
FblI GTMKAC 1 cut(s) 948
Fnu4HI GCNGC 9 cut(s) 273, 313, 562, 681, 851, 888, 1082, 1085, 1417
FokI GGATG 1 cut(s) 1113
Fsp4HI GCNGC 9 cut(s) 273, 313, 562, 681, 851, 888, 1082, 1085, 1417
FspBI CTAG 3 cut(s) 23, 359, 989
FspI TGCGCA 1 cut(s) 679
GlaI GCGC 2 cut(s) 375, 679
GluI GCNGC 9 cut(s) 273, 313, 562, 681, 851, 888, 1082, 1085, 1417
HaeIII GGCC 2 cut(s) 323, 808
HapII CCGG 3 cut(s) 320, 729, 1277
HgaI GACGC 1 cut(s) 512
HhaI GCGC 2 cut(s) 376, 680
Hin6I GCGC 2 cut(s) 374, 678
HinP1I GCGC 2 cut(s) 374, 678
HincII GTYRAC 2 cut(s) 529, 1195
HindII GTYRAC 2 cut(s) 529, 1195
HindIII AAGCTT 1 cut(s) 125
HinfI GANTC 5 cut(s) 34, 342, 491, 950, 1353
HpaI GTTAAC 1 cut(s) 529
HpaII CCGG 3 cut(s) 320, 729, 1277
Hpy166II GTNNAC 5 cut(s) 156, 529, 734, 949, 1195
Hpy188I TCNGA 1 cut(s) 502
Hpy8I GTNNAC 5 cut(s) 156, 529, 734, 949, 1195
Hpy99I CGWCG 1 cut(s) 1384
HpyCH4III ACNGT 3 cut(s) 308, 964, 1040
HpyCH4V TGCA 3 cut(s) 312, 959, 1087
HpyF10VI GCNNNNNNNGC 3 cut(s) 100, 272, 989
HpyF3I CTNAG 6 cut(s) 74, 123, 537, 803, 891, 1181
HspAI GCGC 2 cut(s) 374, 678
Kpn2I TCCGGA 1 cut(s) 1276
Ksp22I TGATCA 1 cut(s) 796
KspAI GTTAAC 1 cut(s) 529
Kzo9I GATC 7 cut(s) 84, 298, 332, 711, 723, 796, 1240
LmnI GCTCC 7 cut(s) 57, 603, 613, 826, 884, 1340, 1390
Lsp1109I GCAGC 9 cut(s) 284, 324, 573, 692, 837, 874, 1071, 1093, 1403
LweI GCATC 1 cut(s) 515
MabI ACCWGGT 1 cut(s) 1132
MaeI CTAG 3 cut(s) 23, 359, 989
MaeIII GTNAC 1 cut(s) 658
MalI GATC 7 cut(s) 86, 300, 334, 713, 725, 798, 1242
MboI GATC 7 cut(s) 84, 298, 332, 711, 723, 796, 1240
MflI RGATCY 3 cut(s) 332, 723, 1240
MluCI AATT 7 cut(s) 567, 607, 1029, 1068, 1209, 1247, 1406
MlyI GAGTC 2 cut(s) 336, 944
MroI TCCGGA 1 cut(s) 1276
MroXI GAANNNNTTC 2 cut(s) 624, 1116
MseI TTAA 6 cut(s) 351, 528, 855, 1218, 1308, 1499
MspA1I CMGCKG 3 cut(s) 266, 683, 1084
MspI CCGG 3 cut(s) 320, 729, 1277
MspR9I CCNGG 4 cut(s) 760, 810, 1134, 1362
MvaI CCWGG 4 cut(s) 760, 810, 1134, 1362
MwoI GCNNNNNNNGC 3 cut(s) 100, 272, 989
NcoI CCATGG 1 cut(s) 1480
NdeII GATC 7 cut(s) 84, 298, 332, 711, 723, 796, 1240
NheI GCTAGC 1 cut(s) 988
NlaIV GGNNCC 1 cut(s) 1138
NsbI TGCGCA 1 cut(s) 679
PagI TCATGA 1 cut(s) 640
PceI AGGCCT 1 cut(s) 808
PdmI GAANNNNTTC 2 cut(s) 624, 1116
PfeI GAWTC 3 cut(s) 34, 491, 1353
PkrI GCNGC 9 cut(s) 274, 314, 563, 682, 852, 889, 1083, 1086, 1418
PleI GAGTC 2 cut(s) 336, 944
PpsI GAGTC 2 cut(s) 336, 944
PpuMI RGGWCCY 1 cut(s) 1136
Psp5II RGGWCCY 1 cut(s) 1136
Psp6I CCWGG 4 cut(s) 758, 808, 1132, 1360
PspGI CCWGG 4 cut(s) 758, 808, 1132, 1360
PspN4I GGNNCC 1 cut(s) 1138
PspPI GGNCC 2 cut(s) 212, 1136
PspPPI RGGWCCY 1 cut(s) 1136
PstI CTGCAG 1 cut(s) 1089
PsuI RGATCY 3 cut(s) 332, 723, 1240
PvuII CAGCTG 3 cut(s) 266, 683, 1084
RsaI GTAC 2 cut(s) 1091, 1398
RsaNI GTAC 2 cut(s) 1090, 1397
SaqAI TTAA 6 cut(s) 351, 528, 855, 1218, 1308, 1499
SatI GCNGC 9 cut(s) 273, 313, 562, 681, 851, 888, 1082, 1085, 1417
Sau3AI GATC 7 cut(s) 84, 298, 332, 711, 723, 796, 1240
Sau96I GGNCC 2 cut(s) 212, 1136
SchI GAGTC 2 cut(s) 336, 944
ScrFI CCNGG 4 cut(s) 760, 810, 1134, 1362
SexAI ACCWGGT 1 cut(s) 1132
SfaNI GCATC 1 cut(s) 515
SfcI CTRYAG 1 cut(s) 1085
SinI GGWCC 2 cut(s) 212, 1136
SmlI CTYRAG 2 cut(s) 419, 1094
SmoI CTYRAG 2 cut(s) 419, 1094
SpeI ACTAGT 1 cut(s) 22
Sse9I AATT 7 cut(s) 567, 607, 1029, 1068, 1209, 1247, 1406
SseBI AGGCCT 1 cut(s) 808
SspI AATATT 1 cut(s) 389
SspMI CTAG 3 cut(s) 23, 359, 989
StuI AGGCCT 1 cut(s) 808
StyD4I CCNGG 4 cut(s) 758, 808, 1132, 1360
StyI CCWWGG 2 cut(s) 598, 1480
TaaI ACNGT 3 cut(s) 308, 964, 1040
TaqI TCGA 4 cut(s) 631, 649, 1120, 1348
TaqII GACCGA 1 cut(s) 259
TasI AATT 7 cut(s) 567, 607, 1029, 1068, 1209, 1247, 1406
TatI WGTACW 1 cut(s) 1396
TfiI GAWTC 3 cut(s) 34, 491, 1353
Tru1I TTAA 6 cut(s) 351, 528, 855, 1218, 1308, 1499
Tru9I TTAA 6 cut(s) 351, 528, 855, 1218, 1308, 1499
TscAI CASTG 3 cut(s) 311, 436, 1069
TseI GCWGC 9 cut(s) 272, 312, 561, 680, 850, 887, 1081, 1084, 1416
TspGWI ACGGA 1 cut(s) 225
TspRI CASTG 3 cut(s) 311, 436, 1069
VpaK11BI GGWCC 2 cut(s) 212, 1136
XapI RAATTY 1 cut(s) 1247
XbaI TCTAGA 1 cut(s) 358
XcmI CCANNNNNNNNNTGG 1 cut(s) 705
XmiI GTMKAC 1 cut(s) 948
XmnI GAANNNNTTC 2 cut(s) 624, 1116
XspI CTAG 3 cut(s) 23, 359, 989
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.