RLG00000019887

Cytochrome p450

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
rosa_laevigata
Chr4
OG0000282
Physical Location & Seq
Reverse (-)
58152997 .. 58154790
1794 bp
Loading structure...
UTR
Exon/CDS
Intron
RLM00000019887

Sequence Viewer

Length: 957 bp
ATGGTGTTGGGTTGTAAAAAGGATGATAGGTTTGATTTGAAAGCCATTGTTAAGGAAACAGTTTCATTGGCTGGGGCTTTCAATATATCTGACTTTGTTCCTTCCCTTGCTGCACTTGATATTCAGGGATTGACTAAGCGCTTAAAGAAAGTTAGCAAGATGATTGATCAACTCCTGGAGAAGATATTACACGAGCATGAACAAGTTGCCAACACTAAGAATGGGAAACAAGGCCAGCATAAGGACTTTGTAGACATGCTGCTTTCGTTAACGAACCAACCGTTGAACTCGAATGATGAGCAACTACACTTCCTTGATCGAAAAAATGTGAAAGCCATCTTACCAGACATACTCGTGGCGGCTATTGATACTTCAGTCACATCAATTGTTTGGAGCCTTGCTGAGCTCTTAAGGCATCCAAGGATCATGAAGAATCTCCAAGAAGAGCTCCAAAGTGTGGTTGGTATGGACCGAATGGTGGACAAATCAGATTTGCCCAAGCTGAATTACTTGAGTATGGTGGTGAAAGAGAGCTTCAGACTACACCCAGTTGTACCGATAGTCCCACGTGAATCTATTGAGGACATTACAATCGATGGATATGACATACCCAAAAAGTCTCGGATCATGGTAAATATCTGGAGCATTGGAAGAGGTCCTAATGTTTGGTCAGAAAATGTGGAGGAATTTTATCCTGAAAGGTTCATGAACAACAATATAGACCTCCGGGAACAAGACTTTCAGCTCATCCCATTTGGGTCTCGGCGAAGAGGGTGTCCGGGTATGCAATTAGGGCTAACCACAGTTCAGCTAGTTCTGGCACAGCTGGTCCACTGCTTTAACTGGGAGCTCCCAACTGGCATGCAACCTCAAGACTTGGACATGTCTGAGAATTTCGGTACATCATTGTCAAAAGCCAAACACTTGCTTGCCAAGCCAACTTACTGTCTTATGTAG

Protein Analysis

319

Amino Acids

36.18

Weight (kDa)

6.46

Isoelectric Point (pI)

39.83

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
p450 PF00067 6 - 306 2.8e-69 Cytochrome P450
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Orthologous Genes (Group: OG0000282)

Species Orthologous Gene IDs
fragaria_vesca FvH4_5g12350 FvH4_5g12380 FvH4_5g12392 FvH4_5g12400 FvH4_5g12430
malus_domestica MD06G1213300.v1.1 MD06G1213500.v1.1 MD06G1213700.v1.1 MD06G1213800.v1.1 MD06G1213900.v1.1 MD06G1214000.v1.1 MD06G1214400.v1.1 MD14G1224300.v1.1 MD14G1224400.v1.1 MD14G1224600.v1.1 MD14G1224700.v1.1 MD14G1224800.v1.1 MD14G1224900.v1.1 MD14G1225100.v1.1 MD14G1225400.v1.1
prunus_persica Prupe.5G219700_v2.0.a1 Prupe.5G219800_v2.0.a1 Prupe.5G219900_v2.0.a1 Prupe.8G078500_v2.0.a1
pyrus_communis pycom06g19100 pycom14g18590 pycom14g18600 pycom14g18610 pycom14g18660
rosa_chinensis RchiOBHm_Chr0c12g0499591 RchiOBHm_Chr2g0140591 RchiOBHm_Chr2g0140631 RchiOBHm_Chr2g0140641 RchiOBHm_Chr2g0140651 RchiOBHm_Chr4g0417991 RchiOBHm_Chr4g0418001 RchiOBHm_Chr4g0418101 RchiOBHm_Chr4g0418111 RchiOBHm_Chr4g0418121 RchiOBHm_Chr6g0280191 RchiOBHm_Chr6g0280241 RchiOBHm_Chr6g0280251 RchiOBHm_Chr7g0185031 RchiOBHm_Chr7g0185051 RchiOBHm_Chr7g0185081 RchiOBHm_Chr7g0185091 RchiOBHm_Chr7g0185111 RchiOBHm_Chr7g0185131 RchiOBHm_Chr7g0185151 RchiOBHm_Chr7g0185161 RchiOBHm_Chr7g0185191 RchiOBHm_Chr7g0222431
rosa_laevigata RLG00000002061 RLG00000004934 RLG00000004935 RLG00000004937 RLG00000013071 RLG00000013077 RLG00000019621 RLG00000019881 RLG00000019884 RLG00000019887 RLG00000019888 RLG00000028839
rosa_multiflora Rmu_co8014370.1_g000001 Rmu_co8334683.1_g000001 Rmu_co8440383.1_g000001 Rmu_sc0002826.1_g000008 Rmu_sc0002826.1_g000009 Rmu_sc0002826.1_g000030 Rmu_sc0004483.1_g000005 Rmu_sc0004638.1_g000003 Rmu_sc0004638.1_g000004 Rmu_sc0005756.1_g000003 Rmu_sc0006493.1_g000023 Rmu_sc0006493.1_g000024 Rmu_sc0007137.1_g000017 Rmu_sc0008496.1_g000022 Rmu_sc0008769.1_g000003 Rmu_sc0013612.1_g000026 Rmu_sc0013864.1_g000001 Rmu_sc0013864.1_g000007 Rmu_sc0013864.1_g000008 Rmu_sc0030128.1_g000001 Rmu_sc0041660.1_g000001 Rmu_ssc0000289.1_g000001
rosa_roxburghii Rroxscaffold_2G00104640 Rroxscaffold_3G00253970 Rroxscaffold_3G00269170 Rroxscaffold_3G00269200 Rroxscaffold_3G00269210 Rroxscaffold_3G00269220 Rroxscaffold_3G00269230 Rroxscaffold_7G00188320
rosa_rugosa Rorug01G0052300 Rorug05G0212000 Rorug06G0130700 Rorug06G0131100 Rorug06G0466200 Rorug06G0466300 Rorug06G0466400 Rorug06G0466500 Rorug06G0466700 Rorug07G0208500 Rorug07G0294600
rosa_samantha Rh4AG137600 Rh6DG237300 Rh6DG237800 Rh7AG076200 Rh7AG076300 Rh7AG076500 Rh7AG076600 Rh7AG350700 Rh7BG070800 Rh7BG070900 Rh7BG071000 Rh7BG071100
rosa_wichuraiana Rw6G020990 Rw6G021010 Rw7G005900 Rw7G005910 Rw7G005920 Rw7G005940 Rw7G005950 Rw7G005970 Rw7G029600

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccB7I CCANNNNNTGG 1 cut(s) 457
AccI GTMKAC 1 cut(s) 252
AciI CCGC 1 cut(s) 359
AclWI GGATC 2 cut(s) 431, 632
AcsI RAATTY 2 cut(s) 686, 892
AcuI CTGAAG 2 cut(s) 357, 520
AcvI CACGTG 1 cut(s) 569
AfaI GTAC 2 cut(s) 555, 901
AfeI AGCGCT 1 cut(s) 140
AfiI CCNNNNNNNGG 3 cut(s) 241, 457, 478
AflII CTTAAG 1 cut(s) 409
AflIII ACRYGT 1 cut(s) 882
AgsI TTSAA 3 cut(s) 40, 82, 286
AjnI CCWGG 1 cut(s) 174
AluBI AGCT 8 cut(s) 406, 448, 502, 534, 745, 811, 826, 850
AluI AGCT 8 cut(s) 406, 448, 502, 534, 745, 811, 826, 850
Alw21I GWGCWC 3 cut(s) 408, 450, 852
Alw26I GTCTC 2 cut(s) 624, 765
AlwI GGATC 2 cut(s) 431, 632
Aor51HI AGCGCT 1 cut(s) 140
AoxI GGCC 1 cut(s) 232
ApeKI GCWGC 2 cut(s) 110, 259
ApoI RAATTY 2 cut(s) 686, 892
ArsI GACNNNNNNTTYG 2 cut(s) 760, 792
AspLEI GCGC 1 cut(s) 141
AspS9I GGNCC 3 cut(s) 469, 656, 829
AsuC2I CCSGG 2 cut(s) 728, 780
AsuHPI GGTGA 1 cut(s) 535
AvaII GGWCC 3 cut(s) 469, 656, 829
BaeI ACNNNNGTAYC 2 cut(s) 360, 393
BanII GRGCYC 3 cut(s) 408, 450, 852
BauI CACGAG 2 cut(s) 191, 353
BbrPI CACGTG 1 cut(s) 569
Bbv12I GWGCWC 3 cut(s) 408, 450, 852
BbvI GCAGC 2 cut(s) 97, 246
BccI CCATC 2 cut(s) 344, 590
BciT130I CCWGG 1 cut(s) 176
BclI TGATCA 1 cut(s) 166
BcnI CCSGG 2 cut(s) 728, 780
BcoDI GTCTC 2 cut(s) 624, 765
BfaI CTAG 1 cut(s) 812
BfoI RGCGCY 1 cut(s) 142
BfrI CTTAAG 1 cut(s) 409
BisI GCNGC 3 cut(s) 111, 260, 360
BlpI GCTNAGC 1 cut(s) 402
BlsI GCNGC 3 cut(s) 112, 261, 361
Bme1390I CCNGG 3 cut(s) 176, 728, 780
Bme18I GGWCC 3 cut(s) 469, 656, 829
BmgT120I GGNCC 3 cut(s) 469, 656, 829
BmiI GGNNCC 1 cut(s) 395
BmrFI CCNGG 3 cut(s) 176, 728, 780
BmrI ACTGGG 2 cut(s) 542, 853
BmsI GCATC 1 cut(s) 424
BmuI ACTGGG 2 cut(s) 542, 853
BpmI CTGGAG 2 cut(s) 197, 661
Bpu1102I GCTNAGC 1 cut(s) 402
BpuEI CTTGAG 2 cut(s) 532, 855
BpuMI CCSGG 2 cut(s) 728, 780
Bsa29I ATCGAT 1 cut(s) 594
BsaAI YACGTR 1 cut(s) 569
BsaI GGTCTC 1 cut(s) 765
BsaJI CCNNGG 1 cut(s) 419
Bsc4I CCNNNNNNNGG 3 cut(s) 241, 457, 478
Bse1I ACTGG 3 cut(s) 548, 848, 862
BseBI CCWGG 1 cut(s) 176
BseCI ATCGAT 1 cut(s) 594
BseDI CCNNGG 1 cut(s) 419
BseGI GGATG 3 cut(s) 28, 415, 747
BseLI CCNNNNNNNGG 3 cut(s) 241, 457, 478
BseMII CTCAG 2 cut(s) 393, 879
BseNI ACTGG 3 cut(s) 548, 848, 862
BseXI GCAGC 2 cut(s) 97, 246
BseYI CCCAGC 1 cut(s) 71
BsgI GTGCAG 1 cut(s) 96
BshFI GGCC 1 cut(s) 234
BshVI ATCGAT 1 cut(s) 594
BsiHKAI GWGCWC 3 cut(s) 408, 450, 852
BsiSI CCGG 2 cut(s) 727, 779
BslFI GGGAC 1 cut(s) 548
BslI CCNNNNNNNGG 3 cut(s) 241, 457, 478
BsmAI GTCTC 2 cut(s) 624, 765
BsmFI GGGAC 1 cut(s) 548
BsnI GGCC 1 cut(s) 234
Bso31I GGTCTC 1 cut(s) 765
Bsp1286I GDGCHC 3 cut(s) 408, 450, 852
Bsp143I GATC 4 cut(s) 166, 316, 423, 624
Bsp1720I GCTNAGC 1 cut(s) 402
BspACI CCGC 1 cut(s) 359
BspANI GGCC 1 cut(s) 234
BspCNI CTCAG 2 cut(s) 394, 880
BspDI ATCGAT 1 cut(s) 594
BspHI TCATGA 2 cut(s) 426, 705
BspLI GGNNCC 1 cut(s) 395
BspPI GGATC 2 cut(s) 431, 632
BspQI GCTCTTC 1 cut(s) 438
BspTI CTTAAG 1 cut(s) 409
BspTNI GGTCTC 1 cut(s) 765
BsrI ACTGG 3 cut(s) 548, 848, 862
BssECI CCNNGG 1 cut(s) 419
BssMI GATC 4 cut(s) 166, 316, 423, 624
BssSI CACGAG 2 cut(s) 191, 353
BssT1I CCWWGG 1 cut(s) 419
Bst2BI CACGAG 2 cut(s) 191, 353
Bst2UI CCWGG 1 cut(s) 176
Bst4CI ACNGT 4 cut(s) 61, 282, 805, 947
Bst6I CTCTTC 3 cut(s) 438, 646, 763
BstAFI CTTAAG 1 cut(s) 409
BstBAI YACGTR 1 cut(s) 569
BstC8I GCNNGC 3 cut(s) 236, 863, 930
BstDEI CTNAG 4 cut(s) 135, 216, 402, 888
BstF5I GGATG 3 cut(s) 28, 415, 747
BstH2I RGCGCY 1 cut(s) 142
BstHHI GCGC 1 cut(s) 141
BstKTI GATC 4 cut(s) 169, 319, 426, 627
BstMAI GTCTC 2 cut(s) 624, 765
BstMBI GATC 4 cut(s) 166, 316, 423, 624
BstMWI GCNNNNNNNGC 3 cut(s) 412, 793, 934
BstNI CCWGG 1 cut(s) 176
BstNSI RCATGY 3 cut(s) 259, 865, 886
BstSCI CCNGG 3 cut(s) 174, 726, 778
BstV1I GCAGC 2 cut(s) 97, 246
Bsu15I ATCGAT 1 cut(s) 594
BsuRI GGCC 1 cut(s) 234
BsuTUI ATCGAT 1 cut(s) 594
BtsCI GGATG 3 cut(s) 28, 415, 747
BtsI GCAGTG 1 cut(s) 832
BtsIMutI CAGTG 1 cut(s) 832
Cac8I GCNNGC 3 cut(s) 236, 863, 930
CciI TCATGA 2 cut(s) 426, 705
CfoI GCGC 1 cut(s) 141
Cfr13I GGNCC 3 cut(s) 469, 656, 829
ClaI ATCGAT 1 cut(s) 594
Csp6I GTAC 2 cut(s) 554, 900
CviAII CATG 7 cut(s) 197, 256, 427, 628, 706, 862, 883
CviQI GTAC 2 cut(s) 554, 900
DdeI CTNAG 4 cut(s) 135, 216, 402, 888
DpnI GATC 4 cut(s) 168, 318, 425, 626
DpnII GATC 4 cut(s) 166, 316, 423, 624
Eam1104I CTCTTC 3 cut(s) 438, 646, 763
EarI CTCTTC 3 cut(s) 438, 646, 763
Ecl136II GAGCTC 3 cut(s) 406, 448, 850
Eco130I CCWWGG 1 cut(s) 419
Eco24I GRGCYC 3 cut(s) 408, 450, 852
Eco31I GGTCTC 1 cut(s) 765
Eco47I GGWCC 3 cut(s) 469, 656, 829
Eco47III AGCGCT 1 cut(s) 140
Eco53kI GAGCTC 3 cut(s) 406, 448, 850
Eco57I CTGAAG 2 cut(s) 357, 520
Eco72I CACGTG 1 cut(s) 569
EcoICRI GAGCTC 3 cut(s) 406, 448, 850
EcoO109I RGGNCCY 1 cut(s) 656
EcoRII CCWGG 1 cut(s) 174
EcoT14I CCWWGG 1 cut(s) 419
EcoT38I GRGCYC 3 cut(s) 408, 450, 852
ErhI CCWWGG 1 cut(s) 419
FaeI CATG 7 cut(s) 200, 259, 430, 631, 709, 865, 886
FaqI GGGAC 1 cut(s) 548
FatI CATG 7 cut(s) 196, 255, 426, 627, 705, 861, 882
FbaI TGATCA 1 cut(s) 166
FblI GTMKAC 1 cut(s) 252
Fnu4HI GCNGC 3 cut(s) 111, 260, 360
FokI GGATG 3 cut(s) 35, 402, 734
FriOI GRGCYC 3 cut(s) 408, 450, 852
Fsp4HI GCNGC 3 cut(s) 111, 260, 360
FspBI CTAG 1 cut(s) 812
GlaI GCGC 1 cut(s) 140
GluI GCNGC 3 cut(s) 111, 260, 360
GsaI CCCAGC 1 cut(s) 75
GsuI CTGGAG 2 cut(s) 197, 661
HaeII RGCGCY 1 cut(s) 142
HaeIII GGCC 1 cut(s) 234
HapII CCGG 2 cut(s) 727, 779
HhaI GCGC 1 cut(s) 141
Hin1II CATG 7 cut(s) 200, 259, 430, 631, 709, 865, 886
Hin6I GCGC 1 cut(s) 139
HinP1I GCGC 1 cut(s) 139
HincII GTYRAC 1 cut(s) 270
HindII GTYRAC 1 cut(s) 270
HinfI GANTC 2 cut(s) 433, 572
HpaI GTTAAC 1 cut(s) 270
HpaII CCGG 2 cut(s) 727, 779
HphI GGTGA 1 cut(s) 535
Hpy166II GTNNAC 4 cut(s) 253, 270, 481, 832
Hpy188I TCNGA 6 cut(s) 91, 490, 539, 624, 673, 889
Hpy188III TCNNGA 5 cut(s) 427, 640, 695, 706, 872
Hpy8I GTNNAC 4 cut(s) 253, 270, 481, 832
HpyAV CCTTC 1 cut(s) 111
HpyCH4III ACNGT 4 cut(s) 61, 282, 805, 947
HpyCH4IV ACGT 1 cut(s) 568
HpyCH4V TGCA 3 cut(s) 113, 787, 865
HpyF10VI GCNNNNNNNGC 3 cut(s) 412, 793, 934
HpyF3I CTNAG 4 cut(s) 135, 216, 402, 888
HpySE526I ACGT 1 cut(s) 568
Hsp92II CATG 7 cut(s) 200, 259, 430, 631, 709, 865, 886
HspAI GCGC 1 cut(s) 139
Ksp22I TGATCA 1 cut(s) 166
KspAI GTTAAC 1 cut(s) 270
Kzo9I GATC 4 cut(s) 166, 316, 423, 624
LguI GCTCTTC 1 cut(s) 438
LmnI GCTCC 5 cut(s) 393, 453, 642, 847, 855
Lsp1109I GCAGC 2 cut(s) 97, 246
LweI GCATC 1 cut(s) 424
MaeI CTAG 1 cut(s) 812
MaeII ACGT 1 cut(s) 568
MaeIII GTNAC 1 cut(s) 376
MalI GATC 4 cut(s) 168, 318, 425, 626
MboI GATC 4 cut(s) 166, 316, 423, 624
MboII GAAGA 5 cut(s) 193, 442, 455, 663, 780
MfeI CAATTG 1 cut(s) 384
MhlI GDGCHC 3 cut(s) 408, 450, 852
MluCI AATT 5 cut(s) 384, 505, 686, 788, 892
MnlI CCTC 6 cut(s) 574, 647, 676, 734, 764, 879
MseI TTAA 5 cut(s) 51, 143, 269, 410, 840
MslI CAYNNNNRTG 2 cut(s) 195, 353
MspA1I CMGCKG 1 cut(s) 826
MspCI CTTAAG 1 cut(s) 409
MspI CCGG 2 cut(s) 727, 779
MspR9I CCNGG 3 cut(s) 176, 728, 780
MunI CAATTG 1 cut(s) 384
MvaI CCWGG 1 cut(s) 176
MwoI GCNNNNNNNGC 3 cut(s) 412, 793, 934
NciI CCSGG 2 cut(s) 728, 780
NdeII GATC 4 cut(s) 166, 316, 423, 624
NlaIII CATG 7 cut(s) 200, 259, 430, 631, 709, 865, 886
NlaIV GGNNCC 1 cut(s) 395
NmeAIII GCCGAG 1 cut(s) 742
NmuCI GTSAC 1 cut(s) 376
NspI RCATGY 3 cut(s) 259, 865, 886
PaeI GCATGC 1 cut(s) 865
PagI TCATGA 2 cut(s) 426, 705
PciI ACATGT 1 cut(s) 882
PciSI GCTCTTC 1 cut(s) 438
PcsI WCGNNNNNNNCGW 1 cut(s) 278
PfeI GAWTC 2 cut(s) 433, 572
PflMI CCANNNNNTGG 1 cut(s) 457
PfoI TCCNGGA 2 cut(s) 174, 726
PkrI GCNGC 3 cut(s) 112, 261, 361
PmaCI CACGTG 1 cut(s) 569
PmlI CACGTG 1 cut(s) 569
Ppu21I YACGTR 1 cut(s) 569
PpuMI RGGWCCY 1 cut(s) 656
PscI ACATGT 1 cut(s) 882
Psp124BI GAGCTC 3 cut(s) 408, 450, 852
Psp5II RGGWCCY 1 cut(s) 656
Psp6I CCWGG 1 cut(s) 174
PspCI CACGTG 1 cut(s) 569
PspFI CCCAGC 1 cut(s) 71
PspGI CCWGG 1 cut(s) 174
PspN4I GGNNCC 1 cut(s) 395
PspPI GGNCC 3 cut(s) 469, 656, 829
PspPPI RGGWCCY 1 cut(s) 656
PvuII CAGCTG 1 cut(s) 826
RsaI GTAC 2 cut(s) 555, 901
RsaNI GTAC 2 cut(s) 554, 900
RseI CAYNNNNRTG 2 cut(s) 195, 353
SacI GAGCTC 3 cut(s) 408, 450, 852
SapI GCTCTTC 1 cut(s) 438
SaqAI TTAA 5 cut(s) 51, 143, 269, 410, 840
SatI GCNGC 3 cut(s) 111, 260, 360
Sau3AI GATC 4 cut(s) 166, 316, 423, 624
Sau96I GGNCC 3 cut(s) 469, 656, 829
ScrFI CCNGG 3 cut(s) 176, 728, 780
SduI GDGCHC 3 cut(s) 408, 450, 852
SfaNI GCATC 1 cut(s) 424
SinI GGWCC 3 cut(s) 469, 656, 829
SmiMI CAYNNNNRTG 2 cut(s) 195, 353
SmlI CTYRAG 3 cut(s) 409, 511, 870
SmoI CTYRAG 3 cut(s) 409, 511, 870
SphI GCATGC 1 cut(s) 865
Sse9I AATT 5 cut(s) 384, 505, 686, 788, 892
SsiI CCGC 1 cut(s) 359
SspMI CTAG 1 cut(s) 812
SstI GAGCTC 3 cut(s) 408, 450, 852
StyD4I CCNGG 3 cut(s) 174, 726, 778
StyI CCWWGG 1 cut(s) 419
TaaI ACNGT 4 cut(s) 61, 282, 805, 947
TaiI ACGT 1 cut(s) 571
TaqI TCGA 3 cut(s) 290, 319, 594
TaqII GACCGA 1 cut(s) 486
TasI AATT 5 cut(s) 384, 505, 686, 788, 892
TauI GCSGC 1 cut(s) 362
TfiI GAWTC 2 cut(s) 433, 572
Tru1I TTAA 5 cut(s) 51, 143, 269, 410, 840
Tru9I TTAA 5 cut(s) 51, 143, 269, 410, 840
TscAI CASTG 1 cut(s) 839
TseFI GTSAC 1 cut(s) 376
TseI GCWGC 2 cut(s) 110, 259
Tsp45I GTSAC 1 cut(s) 376
TspDTI ATGAA 5 cut(s) 54, 213, 443, 694, 722
TspRI CASTG 1 cut(s) 839
Van91I CCANNNNNTGG 1 cut(s) 457
Vha464I CTTAAG 1 cut(s) 409
VpaK11BI GGWCC 3 cut(s) 469, 656, 829
XapI RAATTY 2 cut(s) 686, 892
XceI RCATGY 3 cut(s) 259, 865, 886
XcmI CCANNNNNNNNNTGG 1 cut(s) 458
XmiI GTMKAC 1 cut(s) 252
XspI CTAG 1 cut(s) 812
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.