MD15G1435000.v1.1

bromo domain

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr15
OG0000178
Physical Location & Seq
Forward (+)
53510391 .. 53519228
8838 bp
Loading structure...
UTR
Exon/CDS
Intron
MD15G1435000.v1.1.491

Sequence Viewer

Length: 900 bp
ATGGGGAGTGACTGGTCAGATGGGGATCAAAATGTGAGTTCTTTGGATAGGACAGTGCAGAACTTGCTTAAGAGGTATGGTGAAGTGAATCACCAGATGGCAAACTCATCGAAGCAGATTGACGGTGCGCAAGTGATGCCATTGGCAGTCTCGGGTTCTAGGTGTAGGTTCCAGAATGAGCAAGAATCGCCTGTGCATGAACCTCGTTCTAACAAGAAAGAATTGGGTGCTGCCCTCGCGGTTATTAGGAAAGTTATGAGAATGGATGCAGCTGTACCTTTCAACATTCCCGTGGATCCAATAGCTCTGAGGTTACCTGATTACTTTGATGTCATAGAAATGCCAATGGATTTTGGAACAATTTGCAACCATCTTCAAAATGGTACAAAGTATACAAACTCGGAGGATGTATTCAAGGACGTCCAATACATTTGGGAGAACTGCACCAACTATTACAGTGAGGGTAACTTTCTTTTGGACCTTATGAAACGGGTGAAGGAGAAATTCCTGAAATATTGGGCAGCTGCTGGTTTGTGCAGTAAAGAATGTGGGACAAGTAATGTTTTACCAAGCTCTAATGTGGGGAAAAGGAAGACACGAGGACCTACCCGTAACCTTAAACTAGCTCAAATTCCTCCTGGAGAAAGATTTGAAATCGGCTGGAAGAACCGGAGGGCCGTAGGTGAAGGCTCCACGTTTTTCAAATCAGAGTGTACAGCCCTAGTTAGGCAAACCCGGGAGATACCCCTACAAGTCAAGTCATGGAAGGAAATCCCATTTGATATTAAAAAGAAGGCATTTGAACATGTCTTGGTCCGTACAACAAAAAATTTGGAAGTAGTTCACAGTAGACCAATTAATTTTCCCTTAAATCCTTATTTTTGCATGTTCATCGTGTAA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
Bromodomain Transposase_24

Protein Analysis

300

Amino Acids

34.12

Weight (kDa)

9.15

Isoelectric Point (pI)

40.95

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
Bromodomain PF00439 80 - 160 4.8e-14 Bromodomain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Orthologous Genes (Group: OG0000178)

Species Orthologous Gene IDs
arabidopsis_thaliana AT1G40087 AT3G30200
fragaria_vesca FvH4_1g23271 FvH4_3g22812 FvH4_3g22813 FvH4_3g31042 FvH4_3g31043 FvH4_7g03653
malus_domestica MD05G1321200.v1.1 MD09G1027200.v1.1 MD15G1434900.v1.1 MD15G1435000.v1.1 MD15G1435100.v1.1
prunus_persica Prupe.1G578800_v2.0.a1 Prupe.1G578800_v2.0.a1 Prupe.1G578800_v2.0.a1 Prupe.2G062700_v2.0.a1 Prupe.5G033400_v2.0.a1 Prupe.7G022900_v2.0.a1 Prupe.7G105300_v2.0.a1 Prupe.7G105300_v2.0.a1 Prupe.7G105300_v2.0.a1 Prupe.7G105300_v2.0.a1 Prupe.7G105300_v2.0.a1 Prupe.7G105300_v2.0.a1 Prupe.7G105300_v2.0.a1
pyrus_communis pycom03g07600 pycom03g11360 pycom05g02870 pycom111g02130 pycom15g38370 pycom15g38380
rosa_chinensis RchiOBHm_Chr1g0346371 RchiOBHm_Chr4g0402051 RchiOBHm_Chr4g0414991 RchiOBHm_Chr5g0051011 RchiOBHm_Chr5g0051181 RchiOBHm_Chr6g0273071 RchiOBHm_Chr7g0218301 RchiOBHm_Chr7g0241081
rosa_laevigata RLG00000007709 RLG00000008953 RLG00000012400 RLG00000012401 RLG00000013805 RLG00000014199 RLG00000014726 RLG00000017792 RLG00000017793 RLG00000018860 RLG00000020749 RLG00000030708 RLG00000033507
rosa_multiflora Rmu_co8373761.1_g000001 Rmu_sc0000028.1_g000023 Rmu_sc0000235.1_g000040 Rmu_sc0000293.1_g000017 Rmu_sc0000293.1_g000019 Rmu_sc0000651.1_g000012 Rmu_sc0000870.1_g000051 Rmu_sc0001167.1_g000031 Rmu_sc0001373.1_g000039 Rmu_sc0001861.1_g000055 Rmu_sc0001891.1_g000038 Rmu_sc0001909.1_g000015 Rmu_sc0002500.1_g000002 Rmu_sc0002868.1_g000036 Rmu_sc0002868.1_g000038 Rmu_sc0002868.1_g000039 Rmu_sc0003379.1_g000001 Rmu_sc0003778.1_g000005 Rmu_sc0003778.1_g000006 Rmu_sc0010475.1_g000011 Rmu_sc0015271.1_g000002 Rmu_sc0015271.1_g000003 Rmu_sc0017962.1_g000001 Rmu_sc0017962.1_g000003 Rmu_sc0022129.1_g000004 Rmu_sc0025694.1_g000003 Rmu_sc0025694.1_g000004
rosa_roxburghii Rroxscaffold_1G00031640 Rroxscaffold_1G00047620 Rroxscaffold_1G00047630 Rroxscaffold_1G00050560 Rroxscaffold_1G00050570 Rroxscaffold_1G00054800 Rroxscaffold_1G00055890 Rroxscaffold_2G00108230 Rroxscaffold_3G00240860 Rroxscaffold_4G00299670 Rroxscaffold_4G00299680 Rroxscaffold_4G00299690 Rroxscaffold_4G00306320 Rroxscaffold_4G00306340 Rroxscaffold_5G00341060 Rroxscaffold_5G00342000 Rroxscaffold_5G00355660 Rroxscaffold_5G00357170 Rroxscaffold_6G00399490 Rroxscaffold_6G00408400 Rroxscaffold_7G00189260 Rroxscaffold_7G00199620 Rroxscaffold_7G00215470
rosa_rugosa Rorug02G0117600 Rorug02G0117700 Rorug04G0116400 Rorug06G0103200
rosa_samantha Rh1AG062800 Rh1AG073700 Rh1CG091700 Rh1DG077600 Rh1DG077700 Rh1DG077800 Rh1DG117400 Rh1DG146300 Rh2BG193300 Rh2BG193400 Rh2BG265300 Rh2BG413400 Rh3CG365500 Rh4AG315400 Rh4BG323100 Rh4BG323200 Rh4CG071400 Rh4CG142500 Rh4CG203300 Rh4CG338300 Rh4DG079300 Rh4DG079400 Rh4DG217000 Rh4DG217100 Rh4DG217200 Rh4DG217300 Rh5AG128300 Rh5AG239900 Rh5AG465900 Rh5BG348600 Rh5BG387900 Rh5BG388000 Rh5CG181800 Rh5CG181900 Rh5CG271000 Rh5CG271100 Rh5DG127100 Rh5DG138400 Rh5DG168200 Rh5DG168300 Rh5DG361500 Rh5DG460400 Rh6AG045400 Rh6AG058600 Rh6BG275000 Rh6CG089700 Rh6DG182300 Rh6DG182400 Rh6DG207300 Rh6DG207400 Rh7BG374000 Rh7BG390600 Rh7BG390700 Rh7BG390800
rosa_wichuraiana Rw0G018690 Rw1G007320 Rw4G008510 Rw5G011510 Rw5G021830 Rw6G024150

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AatII GACGTC 1 cut(s) 423
Acc16I TGCGCA 1 cut(s) 129
AccI GTMKAC 2 cut(s) 392, 850
AccII CGCG 1 cut(s) 239
AciI CCGC 1 cut(s) 239
AclWI GGATC 3 cut(s) 33, 290, 303
AcsI RAATTY 3 cut(s) 503, 630, 829
AcyI GRCGYC 1 cut(s) 420
AfaI GTAC 4 cut(s) 276, 385, 715, 820
AfiI CCNNNNNNNGG 1 cut(s) 726
AflII CTTAAG 1 cut(s) 68
AflIII ACRYGT 1 cut(s) 805
AgsI TTSAA 6 cut(s) 283, 377, 415, 653, 703, 803
AjnI CCWGG 1 cut(s) 637
AluBI AGCT 5 cut(s) 272, 305, 524, 573, 626
AluI AGCT 5 cut(s) 272, 305, 524, 573, 626
Alw26I GTCTC 1 cut(s) 154
AlwI GGATC 3 cut(s) 33, 290, 303
AlwNI CAGNNNCTG 1 cut(s) 527
Ama87I CYCGRG 2 cut(s) 151, 735
AoxI GGCC 1 cut(s) 675
ApeKI GCWGC 4 cut(s) 230, 269, 521, 524
ApoI RAATTY 3 cut(s) 503, 630, 829
AseI ATTAAT 1 cut(s) 858
Asp700I GAANNNNTTC 1 cut(s) 840
AspLEI GCGC 1 cut(s) 130
AspS9I GGNCC 4 cut(s) 478, 602, 675, 814
AsuC2I CCSGG 2 cut(s) 736, 737
AsuHPI GGTGA 4 cut(s) 83, 92, 505, 695
AvaI CYCGRG 2 cut(s) 151, 735
AvaII GGWCC 3 cut(s) 478, 602, 814
BamHI GGATCC 1 cut(s) 295
BauI CACGAG 1 cut(s) 597
BbsI GAAGAC 1 cut(s) 599
BbvI GCAGC 4 cut(s) 217, 281, 511, 533
BccI CCATC 3 cut(s) 14, 91, 378
BceAI ACGGC 1 cut(s) 662
BcgI CGANNNNNNTGC 5 cut(s) 90, 124, 185, 219, 874
BciT130I CCWGG 1 cut(s) 639
BcnI CCSGG 2 cut(s) 736, 737
BcoDI GTCTC 1 cut(s) 154
BfaI CTAG 3 cut(s) 159, 623, 722
BfrI CTTAAG 1 cut(s) 68
BisI GCNGC 4 cut(s) 231, 270, 522, 525
BlsI GCNGC 4 cut(s) 232, 271, 523, 526
Bme1390I CCNGG 3 cut(s) 639, 736, 737
Bme18I GGWCC 3 cut(s) 478, 602, 814
BmeT110I CYCGRG 2 cut(s) 151, 735
BmgT120I GGNCC 4 cut(s) 478, 602, 675, 814
BmiI GGNNCC 3 cut(s) 170, 297, 691
BmrFI CCNGG 3 cut(s) 639, 736, 737
BmsI GCATC 2 cut(s) 126, 256
BpiI GAAGAC 1 cut(s) 599
BpmI CTGGAG 1 cut(s) 660
BpuMI CCSGG 2 cut(s) 736, 737
BsaBI GATNNNNATC 1 cut(s) 24
BsaHI GRCGYC 1 cut(s) 420
BsaJI CCNNGG 2 cut(s) 291, 735
BsaWI WCCGGW 1 cut(s) 669
Bsc4I CCNNNNNNNGG 1 cut(s) 726
Bse1I ACTGG 1 cut(s) 17
Bse8I GATNNNNATC 1 cut(s) 24
BseBI CCWGG 1 cut(s) 639
BseDI CCNNGG 2 cut(s) 291, 735
BseGI GGATG 2 cut(s) 271, 412
BseJI GATNNNNATC 1 cut(s) 24
BseLI CCNNNNNNNGG 1 cut(s) 726
BseMII CTCAG 1 cut(s) 299
BseNI ACTGG 1 cut(s) 17
BseXI GCAGC 4 cut(s) 217, 281, 511, 533
BsgI GTGCAG 3 cut(s) 77, 427, 556
Bsh1236I CGCG 1 cut(s) 239
BshFI GGCC 1 cut(s) 677
BsiHKCI CYCGRG 2 cut(s) 151, 735
BsiSI CCGG 2 cut(s) 670, 736
BslFI GGGAC 1 cut(s) 565
BslI CCNNNNNNNGG 1 cut(s) 726
BsmAI GTCTC 1 cut(s) 154
BsmFI GGGAC 1 cut(s) 565
BsnI GGCC 1 cut(s) 677
BsoBI CYCGRG 2 cut(s) 151, 735
Bsp1407I TGTACA 1 cut(s) 713
Bsp143I GATC 2 cut(s) 25, 295
BspACI CCGC 1 cut(s) 239
BspANI GGCC 1 cut(s) 677
BspCNI CTCAG 1 cut(s) 300
BspFNI CGCG 1 cut(s) 239
BspLI GGNNCC 3 cut(s) 170, 297, 691
BspPI GGATC 3 cut(s) 33, 290, 303
BspTI CTTAAG 1 cut(s) 68
BsrGI TGTACA 1 cut(s) 713
BsrI ACTGG 1 cut(s) 17
BssECI CCNNGG 2 cut(s) 291, 735
BssMI GATC 2 cut(s) 25, 295
BssNAI GTATAC 1 cut(s) 393
BssNI GRCGYC 1 cut(s) 420
BssSI CACGAG 1 cut(s) 597
Bst1107I GTATAC 1 cut(s) 393
Bst2BI CACGAG 1 cut(s) 597
Bst2UI CCWGG 1 cut(s) 639
Bst4CI ACNGT 4 cut(s) 55, 125, 458, 848
BstACI GRCGYC 1 cut(s) 420
BstAFI CTTAAG 1 cut(s) 68
BstAPI GCANNNNNTGC 2 cut(s) 64, 136
BstAUI TGTACA 1 cut(s) 713
BstDEI CTNAG 1 cut(s) 308
BstDSI CCRYGG 1 cut(s) 291
BstEII GGTNACC 1 cut(s) 312
BstF5I GGATG 2 cut(s) 271, 412
BstFNI CGCG 1 cut(s) 239
BstHHI GCGC 1 cut(s) 130
BstKTI GATC 2 cut(s) 28, 298
BstMAI GTCTC 1 cut(s) 154
BstMBI GATC 2 cut(s) 25, 295
BstMWI GCNNNNNNNGC 4 cut(s) 64, 136, 187, 236
BstNI CCWGG 1 cut(s) 639
BstNSI RCATGY 2 cut(s) 809, 889
BstPI GGTNACC 1 cut(s) 312
BstSCI CCNGG 3 cut(s) 637, 734, 735
BstUI CGCG 1 cut(s) 239
BstV1I GCAGC 4 cut(s) 217, 281, 511, 533
BstV2I GAAGAC 1 cut(s) 599
BstX2I RGATCY 1 cut(s) 295
BstYI RGATCY 1 cut(s) 295
BstZ17I GTATAC 1 cut(s) 393
BsuRI GGCC 1 cut(s) 677
BtgI CCRYGG 1 cut(s) 291
BtsCI GGATG 2 cut(s) 271, 412
BtsIMutI CAGTG 2 cut(s) 60, 463
CaiI CAGNNNCTG 1 cut(s) 527
CfoI GCGC 1 cut(s) 130
Cfr13I GGNCC 4 cut(s) 478, 602, 675, 814
Cfr9I CCCGGG 1 cut(s) 735
Csp6I GTAC 4 cut(s) 275, 384, 714, 819
CviAII CATG 4 cut(s) 197, 762, 806, 886
CviJI RGCY 9 cut(s) 272, 305, 524, 573, 626, 660, 677, 690, 719
CviKI_1 RGCY 9 cut(s) 272, 305, 524, 573, 626, 660, 677, 690, 719
CviQI GTAC 4 cut(s) 275, 384, 714, 819
DdeI CTNAG 1 cut(s) 308
DpnI GATC 2 cut(s) 27, 297
DpnII GATC 2 cut(s) 25, 295
Eco47I GGWCC 3 cut(s) 478, 602, 814
Eco88I CYCGRG 2 cut(s) 151, 735
Eco91I GGTNACC 1 cut(s) 312
EcoO109I RGGNCCY 1 cut(s) 602
EcoO65I GGTNACC 1 cut(s) 312
EcoRII CCWGG 1 cut(s) 637
FaeI CATG 4 cut(s) 200, 765, 809, 889
FaiI YATR 9 cut(s) 78, 198, 257, 335, 393, 485, 763, 807, 887
FaqI GGGAC 1 cut(s) 565
FatI CATG 4 cut(s) 196, 761, 805, 885
FblI GTMKAC 2 cut(s) 392, 850
Fnu4HI GCNGC 4 cut(s) 231, 270, 522, 525
FokI GGATG 2 cut(s) 278, 419
Fsp4HI GCNGC 4 cut(s) 231, 270, 522, 525
FspBI CTAG 3 cut(s) 159, 623, 722
FspI TGCGCA 1 cut(s) 129
GlaI GCGC 1 cut(s) 129
GluI GCNGC 4 cut(s) 231, 270, 522, 525
GsuI CTGGAG 1 cut(s) 660
HaeIII GGCC 1 cut(s) 677
HapII CCGG 2 cut(s) 670, 736
HhaI GCGC 1 cut(s) 130
Hin1I GRCGYC 1 cut(s) 420
Hin1II CATG 4 cut(s) 200, 765, 809, 889
Hin6I GCGC 1 cut(s) 128
HinP1I GCGC 1 cut(s) 128
HinfI GANTC 2 cut(s) 88, 185
HpaII CCGG 2 cut(s) 670, 736
HphI GGTGA 4 cut(s) 83, 92, 505, 695
Hpy166II GTNNAC 4 cut(s) 393, 714, 844, 851
Hpy188I TCNGA 4 cut(s) 19, 309, 403, 709
Hpy188III TCNNGA 2 cut(s) 172, 508
Hpy8I GTNNAC 4 cut(s) 393, 714, 844, 851
HpyAV CCTTC 4 cut(s) 490, 680, 760, 787
HpyCH4III ACNGT 4 cut(s) 55, 125, 458, 848
HpyCH4IV ACGT 2 cut(s) 420, 695
HpyCH4V TGCA 7 cut(s) 58, 196, 269, 366, 444, 537, 885
HpyF10VI GCNNNNNNNGC 4 cut(s) 64, 136, 187, 236
HpyF3I CTNAG 1 cut(s) 308
HpySE526I ACGT 2 cut(s) 420, 695
Hsp92I GRCGYC 1 cut(s) 420
Hsp92II CATG 4 cut(s) 200, 765, 809, 889
HspAI GCGC 1 cut(s) 128
Kzo9I GATC 2 cut(s) 25, 295
LmnI GCTCC 1 cut(s) 695
Lsp1109I GCAGC 4 cut(s) 217, 281, 511, 533
LweI GCATC 2 cut(s) 126, 256
MaeI CTAG 3 cut(s) 159, 623, 722
MaeII ACGT 2 cut(s) 420, 695
MaeIII GTNAC 4 cut(s) 8, 312, 464, 611
MalI GATC 2 cut(s) 27, 297
MboI GATC 2 cut(s) 25, 295
MboII GAAGA 3 cut(s) 365, 604, 676
MflI RGATCY 1 cut(s) 295
MluCI AATT 7 cut(s) 221, 360, 503, 630, 829, 855, 859
MnlI CCTC 9 cut(s) 66, 213, 245, 303, 397, 454, 593, 645, 666
MroXI GAANNNNTTC 1 cut(s) 840
MseI TTAA 5 cut(s) 69, 618, 786, 858, 869
MslI CAYNNNNRTG 2 cut(s) 290, 338
MspA1I CMGCKG 2 cut(s) 272, 524
MspCI CTTAAG 1 cut(s) 68
MspI CCGG 2 cut(s) 670, 736
MspR9I CCNGG 3 cut(s) 639, 736, 737
MvaI CCWGG 1 cut(s) 639
MvnI CGCG 1 cut(s) 239
MwoI GCNNNNNNNGC 4 cut(s) 64, 136, 187, 236
NciI CCSGG 2 cut(s) 736, 737
NdeII GATC 2 cut(s) 25, 295
NlaIII CATG 4 cut(s) 200, 765, 809, 889
NlaIV GGNNCC 3 cut(s) 170, 297, 691
NmuCI GTSAC 1 cut(s) 8
NsbI TGCGCA 1 cut(s) 129
NspI RCATGY 2 cut(s) 809, 889
PciI ACATGT 1 cut(s) 805
PdmI GAANNNNTTC 1 cut(s) 840
PfeI GAWTC 2 cut(s) 88, 185
PfoI TCCNGGA 1 cut(s) 637
PkrI GCNGC 4 cut(s) 232, 271, 523, 526
PpuMI RGGWCCY 1 cut(s) 602
PscI ACATGT 1 cut(s) 805
PshBI ATTAAT 1 cut(s) 858
Psp5II RGGWCCY 1 cut(s) 602
Psp6I CCWGG 1 cut(s) 637
PspEI GGTNACC 1 cut(s) 312
PspGI CCWGG 1 cut(s) 637
PspN4I GGNNCC 3 cut(s) 170, 297, 691
PspPI GGNCC 4 cut(s) 478, 602, 675, 814
PspPPI RGGWCCY 1 cut(s) 602
PstNI CAGNNNCTG 1 cut(s) 527
PsuI RGATCY 1 cut(s) 295
PvuII CAGCTG 2 cut(s) 272, 524
RsaI GTAC 4 cut(s) 276, 385, 715, 820
RsaNI GTAC 4 cut(s) 275, 384, 714, 819
RseI CAYNNNNRTG 2 cut(s) 290, 338
SaqAI TTAA 5 cut(s) 69, 618, 786, 858, 869
SatI GCNGC 4 cut(s) 231, 270, 522, 525
Sau3AI GATC 2 cut(s) 25, 295
Sau96I GGNCC 4 cut(s) 478, 602, 675, 814
ScrFI CCNGG 3 cut(s) 639, 736, 737
SfaNI GCATC 2 cut(s) 126, 256
SinI GGWCC 3 cut(s) 478, 602, 814
SmaI CCCGGG 1 cut(s) 737
SmiMI CAYNNNNRTG 2 cut(s) 290, 338
SmlI CTYRAG 1 cut(s) 68
SmoI CTYRAG 1 cut(s) 68
Sse9I AATT 7 cut(s) 221, 360, 503, 630, 829, 855, 859
SsiI CCGC 1 cut(s) 239
SspI AATATT 1 cut(s) 515
SspMI CTAG 3 cut(s) 159, 623, 722
StyD4I CCNGG 3 cut(s) 637, 734, 735
TaaI ACNGT 4 cut(s) 55, 125, 458, 848
TaiI ACGT 2 cut(s) 423, 698
TaqI TCGA 1 cut(s) 110
TasI AATT 7 cut(s) 221, 360, 503, 630, 829, 855, 859
TatI WGTACW 1 cut(s) 713
TfiI GAWTC 2 cut(s) 88, 185
Tru1I TTAA 5 cut(s) 69, 618, 786, 858, 869
Tru9I TTAA 5 cut(s) 69, 618, 786, 858, 869
TscAI CASTG 2 cut(s) 60, 463
TseFI GTSAC 1 cut(s) 8
TseI GCWGC 4 cut(s) 230, 269, 521, 524
Tsp45I GTSAC 1 cut(s) 8
TspDTI ATGAA 3 cut(s) 213, 500, 880
TspGWI ACGGA 1 cut(s) 806
TspMI CCCGGG 1 cut(s) 735
TspRI CASTG 2 cut(s) 60, 463
Vha464I CTTAAG 1 cut(s) 68
VpaK11BI GGWCC 3 cut(s) 478, 602, 814
VspI ATTAAT 1 cut(s) 858
XapI RAATTY 3 cut(s) 503, 630, 829
XceI RCATGY 2 cut(s) 809, 889
XcmI CCANNNNNNNNNTGG 1 cut(s) 377
XmaI CCCGGG 1 cut(s) 735
XmiI GTMKAC 2 cut(s) 392, 850
XmnI GAANNNNTTC 1 cut(s) 840
XspI CTAG 3 cut(s) 159, 623, 722
ZraI GACGTC 1 cut(s) 421
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.