MD11G1124200.v1.1

f-box protein

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr11
OG0000289
Physical Location & Seq
Forward (+)
11412687 .. 11413901
1215 bp
Loading structure...
UTR
Exon/CDS
Intron
MD11G1124200.v1.1.491

Sequence Viewer

Length: 1215 bp
ATGGATCAAGACATGGAATCAGCTGGCTCCGAGCTCCCAAGCGAAATCATATGCTATCAGATACTACCAAGGCTGCCGTCTAAGTCCCTCATGCGATTCAAATGCGTAGGCAAGTCTTGGTCCTCTCTCGTCCGCAGCCCTTCCTTTGTCGACGCCCATCAAACCTTCCACCGTAACAAGCTCAATCACCTTCTCCTCACTACTTGGGACAAATCCACAAGGCAACAACACTTCCTCTCTGTGCAAATCAACCAAGAAGGAATTCCAACAGCTGCCACGCACCTTCTAAACCTTCCAACATTGTCCTTCAATCAACGTCTCTACAATGTAGAGAGTATCAACGGCTTGGTCTTCCTTTACCCTTCGAATACCGTGTTCCCCCATCACAATCAAGCCAATCGTGATAATCTTCTTCGCATGTTAAATCCCTCAACACGGGAGTTTATTGCTCTTCCACATGCATTTCCCAGGTGCTGCCGTCGTGCCCATTCTACACATCACTTCGGGTTTAGTCCTCTTACAAATGAATATAAAGTTCTCCAAGTGCAAAGGTTTCAGCCTCGTGATTCTATGACAAGGGCTATGACTTTTATGTTCAAGATATTCAAATTAGGTACAAGTTTATGGAGGTGCATAGAGTTAGACCTTAATGACCTCCCTTTTGATCCTTTCAAGTGCCCGTTTCATAGGAGAAGTGTGAGTGTCAATGGCGCCATACATTGGATGCATGACACACAAAATATCTTAGTGGTTTTCGACATTGCAGATGAGAAATTCAAAGTAATCACAATTCCTCACAATTATAATTGTGCTATACATAAATTTAACTTTGCATATGGGAATATAGTTGAAGTGTTTGGATGTTTGGCGCTAATTGGCGACGAGCAGTTGACACAACAAAATATGATGGGGTTATGGATTTTGAAGGACTACGAAAATCAAGTGTGGGTTAAGGAGACTTTCAGATTTCCCTTTGTTTGGAGTGAATTCGGATACCCCGTCCCTTTCTGTTCCATTCACACAGGTGAGCTCATCCTCCAATCTTCGAAGTTAAGTAGACAACACCCGAATCATGTGAGGCTGCATCTCTACAATATGAAGAGTAAAAGTTTTAGGGAAAGTGAAATTGTTTTGCCCTCCGAATGGAGATTCCAGTATGATACTCGATTGACTTTACTTGCTAGCTTTGATGATAGCGTTGTGCCCTTAAGATGA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
F-box FBA_3

Protein Analysis

405

Amino Acids

47.25

Weight (kDa)

8.9

Isoelectric Point (pI)

44.47

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
FBA_3 PF08268 70 - 377 1.7e-35 F-box associated beta propeller domain
FBA_1 PF07734 135 - 317 2.6e-12 F-box associated beta propeller domain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
Loading...
Style Settings
Image
Tree File
Tip: Beautify your tree with professional tools

Download the Full Tree (.nwk) file, then upload it to any of the following tools to customize colors, fonts, annotations, clades, and branch support.

Publication-ready
iTOL Interactive Tree Of Life · Most popular EvolView Flexible annotations MEGA Desktop phylogenetics suite FigTree Desktop tree editor

Orthologous Genes (Group: OG0000289)

Species Orthologous Gene IDs
fragaria_vesca FvH4_1g12771 FvH4_1g24070 FvH4_1g24080 FvH4_1g24081 FvH4_3g05670 FvH4_3g33611 FvH4_3g43191 FvH4_4g07091 FvH4_4g07100 FvH4_4g28510 FvH4_4g28520 FvH4_4g30181 FvH4_4g30190 FvH4_4g34271 FvH4_4g34340 FvH4_5g31290 FvH4_6g37661 FvH4_7g33810
malus_domestica MD02G1067600.v1.1 MD03G1110700.v1.1 MD11G1124100.v1.1 MD11G1124200.v1.1 MD11G1124500.v1.1 MD13G1020600.v1.1 MD16G1019000.v1.1
prunus_persica Prupe.1G283900_v2.0.a1 Prupe.1G284000_v2.0.a1 Prupe.1G285200_v2.0.a1 Prupe.1G285300_v2.0.a1 Prupe.1G285500_v2.0.a1 Prupe.1G285600_v2.0.a1 Prupe.1G286300_v2.0.a1 Prupe.1G300600_v2.0.a1 Prupe.1G300900_v2.0.a1 Prupe.1G333100_v2.0.a1 Prupe.6G093100_v2.0.a1
pyrus_communis pycom02g05360 pycom04g05300 pycom11g10460 pycom11g10470 pycom11g10510 pycom13g01740 pycom13g01750 pycom13g04550
rosa_chinensis RchiOBHm_Chr2g0138411 RchiOBHm_Chr2g0138421 RchiOBHm_Chr4g0399251 RchiOBHm_Chr4g0436521
rosa_laevigata RLG00000005896 RLG00000005933 RLG00000006379 RLG00000006511 RLG00000009284 RLG00000019741 RLG00000019742 RLG00000019743 RLG00000020150 RLG00000024158 RLG00000024159 RLG00000030139 RLG00000032057
rosa_multiflora Rmu_co8310765.1_g000001 Rmu_co8476365.1_g000001 Rmu_sc0001426.1_g000004 Rmu_sc0001534.1_g000001 Rmu_sc0001534.1_g000009 Rmu_sc0001534.1_g000010 Rmu_sc0001556.1_g000019 Rmu_sc0001556.1_g000020 Rmu_sc0001779.1_g000020 Rmu_sc0003130.1_g000005 Rmu_sc0005961.1_g000007 Rmu_sc0025546.1_g000001 Rmu_sc0035131.1_g000001 Rmu_sc0035132.1_g000001
rosa_roxburghii Rroxscaffold_1G00062740 Rroxscaffold_2G00106090 Rroxscaffold_2G00106130 Rroxscaffold_2G00106210 Rroxscaffold_4G00324740 Rroxscaffold_4G00324760
rosa_rugosa Rorug04G0015700 Rorug04G0015800 Rorug04G0294500 Rorug04G0345900 Rorug04G0345900 Rorug05G0013800 Rorug05G0336100 Rorug05G0446400
rosa_samantha Rh2AG399300 Rh2BG407000 Rh2BG407300 Rh2BG407400 Rh2CG385800 Rh2DG419200 Rh4AG093400 Rh4AG348800 Rh4AG401200 Rh4AG406800 Rh4AG406900 Rh4CG101600 Rh4CG371900 Rh4CG428200 Rh4CG428300 Rh4DG085500 Rh4DG085700 Rh4DG351400 Rh4DG365000 Rh4DG408300 Rh4DG408400 Rh5AG108000 Rh5BG104700 Rh5BG411400 Rh5BG523400 Rh5DG103300 Rh5DG425800
rosa_wichuraiana Rw0G008940 Rw1G005620 Rw3G022740 Rw4G030510 Rw4G034940 Rw5G009440 Rw5G037570 Rw5G046580

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AanI TTATAA 1 cut(s) 804
AccB1I GGYRCC 1 cut(s) 710
AccB7I CCANNNNNTGG 1 cut(s) 720
AccI GTMKAC 2 cut(s) 150, 1057
AciI CCGC 1 cut(s) 133
AclWI GGATC 2 cut(s) 12, 659
AcsI RAATTY 4 cut(s) 261, 773, 821, 986
AcyI GRCGYC 2 cut(s) 153, 711
AfaI GTAC 1 cut(s) 616
AfiI CCNNNNNNNGG 4 cut(s) 435, 720, 978, 1143
AflII CTTAAG 1 cut(s) 1207
AgsI TTSAA 8 cut(s) 100, 310, 598, 607, 673, 778, 851, 925
AjnI CCWGG 1 cut(s) 467
AjuI GAANNNNNNNTTGG 2 cut(s) 246, 278
AleI CACNNNNGTG 1 cut(s) 1023
AluBI AGCT 6 cut(s) 23, 34, 181, 272, 1030, 1185
AluI AGCT 6 cut(s) 23, 34, 181, 272, 1030, 1185
Alw21I GWGCWC 2 cut(s) 36, 1032
Alw26I GTCTC 2 cut(s) 323, 950
AlwI GGATC 2 cut(s) 12, 659
AlwNI CAGNNNCTG 1 cut(s) 474
ApeKI GCWGC 5 cut(s) 73, 135, 272, 474, 1081
ApoI RAATTY 4 cut(s) 261, 773, 821, 986
ArsI GACNNNNNNTTYG 2 cut(s) 644, 676
Asp700I GAANNNNTTC 1 cut(s) 261
AspLEI GCGC 2 cut(s) 713, 871
AspS9I GGNCC 1 cut(s) 120
AsuHPI GGTGA 2 cut(s) 179, 1037
AsuII TTCGAA 2 cut(s) 365, 1046
AsuNHI GCTAGC 1 cut(s) 1181
AvaII GGWCC 1 cut(s) 120
BaeGI GKGCMC 3 cut(s) 487, 680, 1206
BanI GGYRCC 1 cut(s) 710
BanII GRGCYC 2 cut(s) 36, 1032
BauI CACGAG 1 cut(s) 561
BbsI GAAGAC 1 cut(s) 343
Bbv12I GWGCWC 2 cut(s) 36, 1032
BbvI GCAGC 5 cut(s) 60, 147, 259, 461, 1068
BccI CCATC 3 cut(s) 165, 390, 901
BceAI ACGGC 3 cut(s) 61, 358, 462
BcgI CGANNNNNNTGC 2 cut(s) 84, 118
BciT130I CCWGG 1 cut(s) 469
BciVI GTATCC 1 cut(s) 986
BcoDI GTCTC 2 cut(s) 323, 950
BfaI CTAG 1 cut(s) 1182
BfoI RGCGCY 2 cut(s) 714, 872
BfrI CTTAAG 1 cut(s) 1207
BfuI GTATCC 1 cut(s) 986
BisI GCNGC 5 cut(s) 74, 136, 273, 475, 1082
BlsI GCNGC 5 cut(s) 75, 137, 274, 476, 1083
Bme1390I CCNGG 1 cut(s) 469
Bme18I GGWCC 1 cut(s) 120
BmgT120I GGNCC 1 cut(s) 120
BmiI GGNNCC 2 cut(s) 28, 712
BmrFI CCNGG 1 cut(s) 469
BmsI GCATC 2 cut(s) 714, 1093
BmtI GCTAGC 1 cut(s) 1185
BpiI GAAGAC 1 cut(s) 343
Bpu14I TTCGAA 2 cut(s) 365, 1046
BsaHI GRCGYC 2 cut(s) 153, 711
BsaJI CCNNGG 2 cut(s) 68, 467
Bsc4I CCNNNNNNNGG 4 cut(s) 435, 720, 978, 1143
Bse1I ACTGG 1 cut(s) 1153
Bse3DI GCAATG 1 cut(s) 759
BseBI CCWGG 1 cut(s) 469
BseDI CCNNGG 2 cut(s) 68, 467
BseGI GGATG 3 cut(s) 729, 866, 1032
BseLI CCNNNNNNNGG 4 cut(s) 435, 720, 978, 1143
BseMI GCAATG 1 cut(s) 759
BseNI ACTGG 1 cut(s) 1153
BseRI GAGGAG 1 cut(s) 185
BseSI GKGCMC 3 cut(s) 487, 680, 1206
BseXI GCAGC 5 cut(s) 60, 147, 259, 461, 1068
BshNI GGYRCC 1 cut(s) 710
BsiHKAI GWGCWC 2 cut(s) 36, 1032
BslFI GGGAC 3 cut(s) 70, 221, 986
BslI CCNNNNNNNGG 4 cut(s) 435, 720, 978, 1143
BsmAI GTCTC 2 cut(s) 323, 950
BsmBI CGTCTC 1 cut(s) 323
BsmFI GGGAC 3 cut(s) 70, 221, 986
Bsp119I TTCGAA 2 cut(s) 365, 1046
Bsp1286I GDGCHC 5 cut(s) 36, 487, 680, 1032, 1206
Bsp143I GATC 2 cut(s) 4, 664
BspACI CCGC 1 cut(s) 133
BspLI GGNNCC 2 cut(s) 28, 712
BspOI GCTAGC 1 cut(s) 1185
BspPI GGATC 2 cut(s) 12, 659
BspQI GCTCTTC 1 cut(s) 456
BspT104I TTCGAA 2 cut(s) 365, 1046
BspT107I GGYRCC 1 cut(s) 710
BspTI CTTAAG 1 cut(s) 1207
BsrDI GCAATG 1 cut(s) 759
BsrI ACTGG 1 cut(s) 1153
BssECI CCNNGG 2 cut(s) 68, 467
BssMI GATC 2 cut(s) 4, 664
BssNI GRCGYC 2 cut(s) 153, 711
BssSI CACGAG 1 cut(s) 561
BssT1I CCWWGG 1 cut(s) 68
Bst2BI CACGAG 1 cut(s) 561
Bst2UI CCWGG 1 cut(s) 469
Bst4CI ACNGT 2 cut(s) 173, 373
Bst6I CTCTTC 2 cut(s) 456, 1094
BstACI GRCGYC 2 cut(s) 153, 711
BstAFI CTTAAG 1 cut(s) 1207
BstBI TTCGAA 2 cut(s) 365, 1046
BstC8I GCNNGC 2 cut(s) 25, 1183
BstDEI CTNAG 2 cut(s) 81, 745
BstF5I GGATG 3 cut(s) 729, 866, 1032
BstH2I RGCGCY 2 cut(s) 714, 872
BstHHI GCGC 2 cut(s) 713, 871
BstKTI GATC 2 cut(s) 7, 667
BstMAI GTCTC 2 cut(s) 323, 950
BstMBI GATC 2 cut(s) 4, 664
BstNI CCWGG 1 cut(s) 469
BstNSI RCATGY 2 cut(s) 421, 461
BstSCI CCNGG 1 cut(s) 467
BstSLI GKGCMC 3 cut(s) 487, 680, 1206
BstV1I GCAGC 5 cut(s) 60, 147, 259, 461, 1068
BstV2I GAAGAC 1 cut(s) 343
BsuI GTATCC 1 cut(s) 986
BtsCI GGATG 3 cut(s) 729, 866, 1032
Cac8I GCNNGC 2 cut(s) 25, 1183
CaiI CAGNNNCTG 1 cut(s) 474
CfoI GCGC 2 cut(s) 713, 871
Cfr13I GGNCC 1 cut(s) 120
CseI GACGC 1 cut(s) 161
Csp6I GTAC 1 cut(s) 615
CviAII CATG 6 cut(s) 13, 91, 418, 458, 728, 1073
CviQI GTAC 1 cut(s) 615
DdeI CTNAG 2 cut(s) 81, 745
DinI GGCGCC 1 cut(s) 712
DpnI GATC 2 cut(s) 6, 666
DpnII GATC 2 cut(s) 4, 664
Eam1104I CTCTTC 2 cut(s) 456, 1094
EarI CTCTTC 2 cut(s) 456, 1094
Ecl136II GAGCTC 2 cut(s) 34, 1030
Eco130I CCWWGG 1 cut(s) 68
Eco24I GRGCYC 2 cut(s) 36, 1032
Eco47I GGWCC 1 cut(s) 120
Eco53kI GAGCTC 2 cut(s) 34, 1030
EcoICRI GAGCTC 2 cut(s) 34, 1030
EcoRI GAATTC 2 cut(s) 261, 986
EcoRII CCWGG 1 cut(s) 467
EcoT14I CCWWGG 1 cut(s) 68
EcoT22I ATGCAT 2 cut(s) 463, 729
EcoT38I GRGCYC 2 cut(s) 36, 1032
EgeI GGCGCC 1 cut(s) 712
EheI GGCGCC 1 cut(s) 712
ErhI CCWWGG 1 cut(s) 68
Esp3I CGTCTC 1 cut(s) 323
FaeI CATG 6 cut(s) 16, 94, 421, 461, 731, 1076
FaqI GGGAC 3 cut(s) 70, 221, 986
FatI CATG 6 cut(s) 12, 90, 417, 457, 727, 1072
FauNDI CATATG 2 cut(s) 50, 835
FblI GTMKAC 2 cut(s) 150, 1057
Fnu4HI GCNGC 5 cut(s) 74, 136, 273, 475, 1082
FokI GGATG 3 cut(s) 736, 873, 1019
FriOI GRGCYC 2 cut(s) 36, 1032
Fsp4HI GCNGC 5 cut(s) 74, 136, 273, 475, 1082
FspBI CTAG 1 cut(s) 1182
GlaI GCGC 2 cut(s) 712, 870
GluI GCNGC 5 cut(s) 74, 136, 273, 475, 1082
HaeII RGCGCY 2 cut(s) 714, 872
HgaI GACGC 1 cut(s) 161
HhaI GCGC 2 cut(s) 713, 871
Hin1I GRCGYC 2 cut(s) 153, 711
Hin1II CATG 6 cut(s) 16, 94, 421, 461, 731, 1076
Hin6I GCGC 2 cut(s) 711, 869
HinP1I GCGC 2 cut(s) 711, 869
HincII GTYRAC 2 cut(s) 151, 891
HindII GTYRAC 2 cut(s) 151, 891
HinfI GANTC 5 cut(s) 17, 96, 566, 1069, 1149
HphI GGTGA 2 cut(s) 179, 1037
Hpy166II GTNNAC 3 cut(s) 151, 891, 1058
Hpy188I TCNGA 5 cut(s) 31, 60, 965, 992, 1141
Hpy188III TCNNGA 4 cut(s) 8, 401, 563, 598
Hpy8I GTNNAC 3 cut(s) 151, 891, 1058
Hpy99I CGWCG 3 cut(s) 155, 483, 884
HpyAV CCTTC 9 cut(s) 150, 175, 200, 251, 293, 302, 316, 372, 919
HpyCH4III ACNGT 2 cut(s) 173, 373
HpyCH4IV ACGT 1 cut(s) 316
HpyCH4V TGCA 8 cut(s) 244, 461, 547, 633, 727, 764, 833, 1084
HpyF3I CTNAG 2 cut(s) 81, 745
HpySE526I ACGT 1 cut(s) 316
Hsp92I GRCGYC 2 cut(s) 153, 711
Hsp92II CATG 6 cut(s) 16, 94, 421, 461, 731, 1076
HspAI GCGC 2 cut(s) 711, 869
KasI GGCGCC 1 cut(s) 710
Kzo9I GATC 2 cut(s) 4, 664
LguI GCTCTTC 1 cut(s) 456
LmnI GCTCC 2 cut(s) 32, 39
LpnPI CCDG 5 cut(s) 9, 454, 481, 1008, 1166
Lsp1109I GCAGC 5 cut(s) 60, 147, 259, 461, 1068
LweI GCATC 2 cut(s) 714, 1093
MaeI CTAG 1 cut(s) 1182
MaeII ACGT 1 cut(s) 316
MaeIII GTNAC 1 cut(s) 173
MalI GATC 2 cut(s) 6, 666
MboI GATC 2 cut(s) 4, 664
MboII GAAGA 6 cut(s) 343, 401, 404, 443, 1035, 1111
MhlI GDGCHC 5 cut(s) 36, 487, 680, 1032, 1206
Mly113I GGCGCC 1 cut(s) 711
MmeI TCCRAC 2 cut(s) 290, 320
Mph1103I ATGCAT 2 cut(s) 463, 729
MroXI GAANNNNTTC 1 cut(s) 261
MseI TTAA 6 cut(s) 422, 648, 825, 951, 1052, 1208
MslI CAYNNNNRTG 1 cut(s) 1023
MspA1I CMGCKG 2 cut(s) 23, 272
MspCI CTTAAG 1 cut(s) 1207
MspR9I CCNGG 1 cut(s) 469
MvaI CCWGG 1 cut(s) 469
NarI GGCGCC 1 cut(s) 711
NdeI CATATG 2 cut(s) 50, 835
NdeII GATC 2 cut(s) 4, 664
NheI GCTAGC 1 cut(s) 1181
NlaIII CATG 6 cut(s) 16, 94, 421, 461, 731, 1076
NlaIV GGNNCC 2 cut(s) 28, 712
NsiI ATGCAT 2 cut(s) 463, 729
NspI RCATGY 2 cut(s) 421, 461
NspV TTCGAA 2 cut(s) 365, 1046
OliI CACNNNNGTG 1 cut(s) 1023
PciSI GCTCTTC 1 cut(s) 456
PcsI WCGNNNNNNNCGW 1 cut(s) 996
PdmI GAANNNNTTC 1 cut(s) 261
PfeI GAWTC 5 cut(s) 17, 96, 566, 1069, 1149
PflMI CCANNNNNTGG 1 cut(s) 720
PkrI GCNGC 5 cut(s) 75, 137, 274, 476, 1083
PluTI GGCGCC 1 cut(s) 714
PsiI TTATAA 1 cut(s) 804
Psp124BI GAGCTC 2 cut(s) 36, 1032
Psp6I CCWGG 1 cut(s) 467
PspGI CCWGG 1 cut(s) 467
PspN4I GGNNCC 2 cut(s) 28, 712
PspPI GGNCC 1 cut(s) 120
PstNI CAGNNNCTG 1 cut(s) 474
PvuII CAGCTG 2 cut(s) 23, 272
RsaI GTAC 1 cut(s) 616
RsaNI GTAC 1 cut(s) 615
RseI CAYNNNNRTG 1 cut(s) 1023
SacI GAGCTC 2 cut(s) 36, 1032
SalI GTCGAC 1 cut(s) 149
SapI GCTCTTC 1 cut(s) 456
SaqAI TTAA 6 cut(s) 422, 648, 825, 951, 1052, 1208
SatI GCNGC 5 cut(s) 74, 136, 273, 475, 1082
Sau3AI GATC 2 cut(s) 4, 664
Sau96I GGNCC 1 cut(s) 120
ScrFI CCNGG 1 cut(s) 469
SduI GDGCHC 5 cut(s) 36, 487, 680, 1032, 1206
SfaNI GCATC 2 cut(s) 714, 1093
SfoI GGCGCC 1 cut(s) 712
SfuI TTCGAA 2 cut(s) 365, 1046
SinI GGWCC 1 cut(s) 120
SmiMI CAYNNNNRTG 1 cut(s) 1023
SmlI CTYRAG 1 cut(s) 1207
SmoI CTYRAG 1 cut(s) 1207
SsiI CCGC 1 cut(s) 133
SspDI GGCGCC 1 cut(s) 710
SspMI CTAG 1 cut(s) 1182
SstI GAGCTC 2 cut(s) 36, 1032
StyD4I CCNGG 1 cut(s) 467
StyI CCWWGG 1 cut(s) 68
TaaI ACNGT 2 cut(s) 173, 373
TaiI ACGT 1 cut(s) 319
TaqI TCGA 5 cut(s) 150, 365, 756, 1046, 1165
TfiI GAWTC 5 cut(s) 17, 96, 566, 1069, 1149
Tru1I TTAA 6 cut(s) 422, 648, 825, 951, 1052, 1208
Tru9I TTAA 6 cut(s) 422, 648, 825, 951, 1052, 1208
TseI GCWGC 5 cut(s) 73, 135, 272, 474, 1081
TspDTI ATGAA 3 cut(s) 540, 674, 1112
Van91I CCANNNNNTGG 1 cut(s) 720
Vha464I CTTAAG 1 cut(s) 1207
VpaK11BI GGWCC 1 cut(s) 120
XapI RAATTY 4 cut(s) 261, 773, 821, 986
XceI RCATGY 2 cut(s) 421, 461
XmiI GTMKAC 2 cut(s) 150, 1057
XmnI GAANNNNTTC 1 cut(s) 261
XspI CTAG 1 cut(s) 1182
Zsp2I ATGCAT 2 cut(s) 463, 729
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.