Rroxscaffold_2G00103570

LRR receptor-like serine threonine-protein kinase

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
rosa_roxburghii
GWHEROQ00000002
OG0000083
Physical Location & Seq
Forward (+)
26478867 .. 26480416
1550 bp
Loading structure...
UTR
Exon/CDS
Intron
Rroxscaffold_2G00103570.1

Sequence Viewer

Length: 897 bp
ATGTATACAATTTCCATACTATATGTAGAAGTCACAGTTCAGTTTGGGACATTGGTGTCATCAAAGCGAAAGTTTGCGCACTCTGAAATAATCAAGATCACCAATAACTTTGAGAGGATTCTTGGCAAAGGTGGATTTGGAACAGTGTATCATGGACACCTAGACGACACTCAAGTAGCTGTCAAAATGCTTTCGCCATCATCAGTTCGAGGGTTTCAACAATTTCACGCTGAGGCATGTAGCAGTTCACATATCATAAGCTGGGAAGGTAGACTTAGAATAGCATCAGATGCCGCACAAGGATTGCAGTACTTGCACTATGGTATTAAGCCGCCAATAATCCATAGGGATGTGAAATCAACAAACATTTTGTTGAATGAAAATTTCCAAGCCAAGGTATCAGACTTTGGCCTATCCAAAAACTTTCCTACAGAGGTTGGGACTCATATATCGACAACTGTTGCAGGAACTCCTGGATACCTTGACCCTGAGTATTACCTATCAAACAGGTTAACTGAGAAAAGCGATGTTTATAGCTTCGGGATTGTGCTGTTGGAGATTATCACAGGTCGACCTGCTTTATCCGATGAGAGAATTCACATTAGCCAATGGGTTGGTTTCATGCTTGAAACAGGAAACATTTACAGTATTGTCGATCCCAGGTTGAAGGGAAATGTCACTGTCAACTCTGTGTGGAAAGCTGTGGAGATAGCAATGGCATGTGTGTCCTCAAGTGCCATAAAAAGGCCAATTATGAGTCAAGTAGTTATAGAACTACAGGAGTGTTTGGCGACACAAATGGGTGAAACAAAGCATAACAATGGAACAGAATTAACATGTTCCACTGACCTGATGTCTAACAATTCCATTGTTATGCTAAGTCCCTCTGTGAGGTAG
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
LRR_8 Malectin_like Pkinase Pkinase_Tyr

Protein Analysis

298

Amino Acids

32.96

Weight (kDa)

6.79

Isoelectric Point (pI)

41.96

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
PK_Tyr_Ser-Thr PF07714 86 - 256 1.2e-22 Protein tyrosine and serine/threonine kinase
Pkinase PF00069 91 - 206 1.4e-24 Protein kinase domain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
iTOL Interactive Tree Of Life · Most popular EvolView Flexible annotations MEGA Desktop phylogenetics suite FigTree Desktop tree editor

Orthologous Genes (Group: OG0000083)

Species Orthologous Gene IDs
arabidopsis_thaliana AT1G07560 AT1G51790 AT1G51790 AT1G51790 AT1G51800 AT1G51805 AT1G51805 AT1G51810 AT1G51820 AT1G51820 AT1G51830 AT1G51830 AT1G51840 AT1G51840 AT1G51840 AT1G51840 AT1G51840 AT1G51850 AT1G51850 AT1G51860 AT1G51860 AT1G51870 AT1G51870 AT1G51880 AT1G51880 AT1G51880 AT1G51890 AT1G51890 AT1G51890 AT1G51890 AT1G51890 AT1G51910 AT2G04300 AT2G04300 AT2G28960 AT2G28960 AT2G28970 AT2G28970 AT2G28990 AT2G28990 AT2G29000 AT3G21340 AT3G46350 AT5G59616 AT5G59650 AT5G59650 AT5G59660 AT5G59660 AT5G59660 AT5G59670 AT5G59670 AT5G59680
fragaria_vesca FvH4_2g03270 FvH4_3g21300 FvH4_6g32660 FvH4_6g32660 FvH4_6g32670 FvH4_6g32670 FvH4_6g32690 FvH4_6g32690 FvH4_6g32691 FvH4_6g32700 FvH4_6g32740 FvH4_6g32750 FvH4_6g33210 FvH4_6g33210 FvH4_7g24270 FvH4_7g24280 FvH4_7g24291 FvH4_7g24300
malus_domestica MD09G1198400.v1.1 MD09G1198600.v1.1 MD09G1199100.v1.1 MD09G1199200.v1.1 MD09G1199300.v1.1 MD09G1199500.v1.1 MD09G1199600.v1.1 MD17G1179300.v1.1 MD17G1180200.v1.1 MD17G1266000.v1.1
prunus_persica Prupe.1G438900_v2.0.a1 Prupe.1G439000_v2.0.a1 Prupe.1G439100_v2.0.a1 Prupe.3G019400_v2.0.a1 Prupe.3G021900_v2.0.a1 Prupe.3G054500_v2.0.a1 Prupe.3G054500_v2.0.a1 Prupe.3G055100_v2.0.a1 Prupe.3G055400_v2.0.a1 Prupe.3G055500_v2.0.a1 Prupe.3G055600_v2.0.a1 Prupe.3G055700_v2.0.a1 Prupe.3G055800_v2.0.a1 Prupe.3G055900_v2.0.a1 Prupe.3G055900_v2.0.a1 Prupe.3G056000_v2.0.a1 Prupe.3G056000_v2.0.a1 Prupe.3G056100_v2.0.a1 Prupe.3G209600_v2.0.a1 Prupe.3G209700_v2.0.a1 Prupe.6G291100_v2.0.a1 Prupe.7G208900_v2.0.a1 Prupe.8G038300_v2.0.a1
pyrus_communis pycom09g11570 pycom09g11580 pycom09g11610 pycom09g11630 pycom09g11640 pycom17g18840 pycom17g18910 pycom17g18930 pycom17g18940
rosa_chinensis RchiOBHm_Chr1g0317521 RchiOBHm_Chr1g0317541 RchiOBHm_Chr2g0123351 RchiOBHm_Chr2g0141181 RchiOBHm_Chr2g0141191 RchiOBHm_Chr2g0141211 RchiOBHm_Chr2g0141221 RchiOBHm_Chr2g0141261 RchiOBHm_Chr2g0141271 RchiOBHm_Chr2g0141311 RchiOBHm_Chr2g0141331 RchiOBHm_Chr2g0141371 RchiOBHm_Chr2g0141391 RchiOBHm_Chr2g0141401 RchiOBHm_Chr2g0141431 RchiOBHm_Chr2g0141481 RchiOBHm_Chr2g0141491 RchiOBHm_Chr2g0141591 RchiOBHm_Chr2g0141601 RchiOBHm_Chr2g0141611 RchiOBHm_Chr2g0141631 RchiOBHm_Chr2g0141641 RchiOBHm_Chr2g0141661 RchiOBHm_Chr2g0141681 RchiOBHm_Chr2g0141701 RchiOBHm_Chr2g0141781 RchiOBHm_Chr2g0141811 RchiOBHm_Chr2g0141821 RchiOBHm_Chr3g0479311 RchiOBHm_Chr3g0495751 RchiOBHm_Chr4g0404741 RchiOBHm_Chr4g0410341 RchiOBHm_Chr4g0418371 RchiOBHm_Chr4g0438651 RchiOBHm_Chr5g0036411 RchiOBHm_Chr5g0036491 RchiOBHm_Chr5g0042391 RchiOBHm_Chr6g0279871 RchiOBHm_Chr7g0192921 RchiOBHm_Chr7g0214901 RchiOBHm_Chr7g0234931
rosa_laevigata RLG00000003432 RLG00000008806 RLG00000013062 RLG00000019514 RLG00000019923 RLG00000019924 RLG00000019925 RLG00000019930 RLG00000019931 RLG00000019934 RLG00000019937 RLG00000019938 RLG00000033697
rosa_multiflora Rmu_co8002302.1_g000001 Rmu_sc0000147.1_g000031 Rmu_sc0000463.1_g000005 Rmu_sc0000712.1_g000003 Rmu_sc0001483.1_g000017 Rmu_sc0001554.1_g000002 Rmu_sc0001554.1_g000005 Rmu_sc0001554.1_g000008 Rmu_sc0001981.1_g000017 Rmu_sc0002040.1_g000056 Rmu_sc0002755.1_g000018 Rmu_sc0002804.1_g000016 Rmu_sc0002928.1_g000015 Rmu_sc0003040.1_g000008 Rmu_sc0003040.1_g000018 Rmu_sc0004512.1_g000001 Rmu_sc0004512.1_g000004 Rmu_sc0005507.1_g000001 Rmu_sc0005507.1_g000009 Rmu_sc0005507.1_g000033 Rmu_sc0005507.1_g000037 Rmu_sc0005507.1_g000043 Rmu_sc0005507.1_g000047 Rmu_sc0006318.1_g000004 Rmu_sc0006318.1_g000014 Rmu_sc0006318.1_g000021 Rmu_sc0006556.1_g000001 Rmu_sc0007208.1_g000002 Rmu_sc0007208.1_g000003 Rmu_sc0007208.1_g000006 Rmu_sc0007208.1_g000008
rosa_roxburghii Rroxscaffold_1G00044430 Rroxscaffold_2G00103420 Rroxscaffold_2G00103470 Rroxscaffold_2G00103490 Rroxscaffold_2G00103500 Rroxscaffold_2G00103520 Rroxscaffold_2G00103530 Rroxscaffold_2G00103540 Rroxscaffold_2G00103550 Rroxscaffold_2G00103570 Rroxscaffold_2G00103770 Rroxscaffold_2G00103780 Rroxscaffold_2G00103800 Rroxscaffold_2G00103820 Rroxscaffold_2G00103860 Rroxscaffold_2G00103890 Rroxscaffold_2G00103930 Rroxscaffold_2G00103940 Rroxscaffold_2G00104010 Rroxscaffold_2G00104030 Rroxscaffold_2G00104050 Rroxscaffold_2G00104060 Rroxscaffold_2G00104070 Rroxscaffold_2G00104090 Rroxscaffold_2G00104100 Rroxscaffold_2G00104120 Rroxscaffold_2G00104130 Rroxscaffold_4G00331710
rosa_rugosa Rorug02G0367500 Rorug02G0367500 Rorug02G0367600 Rorug02G0367800 Rorug02G0367800 Rorug02G0367900 Rorug02G0368100 Rorug02G0368100 Rorug02G0368100 Rorug02G0368200 Rorug02G0368700 Rorug02G0368900 Rorug05G0155600 Rorug05G0155700 Rorug05G0155800 Rorug05G0156700 Rorug05G0157300
rosa_samantha Rh1AG028000 Rh2AG418700 Rh2AG418900 Rh2AG419000 Rh2AG419100 Rh2AG419400 Rh2AG419600 Rh2AG419800 Rh2AG420400 Rh2AG421000 Rh2BG428500 Rh2BG428600 Rh2BG428800 Rh2BG428900 Rh2BG429300 Rh2BG429400 Rh2BG429700 Rh2BG429900 Rh2BG430000 Rh2BG430700 Rh2CG405100 Rh2CG405200 Rh2CG405300 Rh2CG405500 Rh2CG405600 Rh2CG405700 Rh2CG406000 Rh2CG406100 Rh2CG406300 Rh2CG406600 Rh2CG406700 Rh2CG407500 Rh2CG408100 Rh2DG438500 Rh3DG123900 Rh3DG124000 Rh5BG249700 Rh5BG482500 Rh5CG281500 Rh5CG507300 Rh7DG133300
rosa_wichuraiana Rw0G019720 Rw0G019730 Rw0G019750 Rw0G023010 Rw2G034340 Rw2G034350 Rw2G034370 Rw2G034380 Rw2G034400 Rw2G034430 Rw2G034470 Rw2G034480 Rw2G034510 Rw5G022890 Rw5G026410 Rw5G032710 Rw5G042850

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AasI GACNNNNNNGTC 1 cut(s) 55
Acc16I TGCGCA 1 cut(s) 78
Acc36I ACCTGC 1 cut(s) 583
AccI GTMKAC 3 cut(s) 5, 271, 571
AciI CCGC 2 cut(s) 294, 332
AclWI GGATC 1 cut(s) 650
AcsI RAATTY 2 cut(s) 382, 594
AfaI GTAC 1 cut(s) 311
AfiI CCNNNNNNNGG 3 cut(s) 394, 744, 891
AflIII ACRYGT 1 cut(s) 836
AgsI TTSAA 4 cut(s) 218, 376, 629, 667
AhdI GACNNNNNGTC 1 cut(s) 853
AjnI CCWGG 2 cut(s) 472, 659
AluBI AGCT 4 cut(s) 179, 261, 537, 701
AluI AGCT 4 cut(s) 179, 261, 537, 701
AlwI GGATC 1 cut(s) 650
AoxI GGCC 2 cut(s) 409, 746
ApoI RAATTY 2 cut(s) 382, 594
AspLEI GCGC 1 cut(s) 79
AsuHPI GGTGA 2 cut(s) 91, 815
BbvCI CCTCAGC 1 cut(s) 231
BccI CCATC 1 cut(s) 205
BciT130I CCWGG 2 cut(s) 474, 661
BciVI GTATCC 1 cut(s) 470
BfaI CTAG 1 cut(s) 161
BfmI CTRYAG 2 cut(s) 429, 776
BfuAI ACCTGC 1 cut(s) 583
BfuI GTATCC 1 cut(s) 470
BisI GCNGC 2 cut(s) 294, 332
BlsI GCNGC 2 cut(s) 295, 333
BmcAI AGTACT 1 cut(s) 311
Bme1390I CCNGG 2 cut(s) 474, 661
BmeRI GACNNNNNGTC 1 cut(s) 853
BmrFI CCNGG 2 cut(s) 474, 661
BmsI GCATC 2 cut(s) 280, 293
Bpu10I CCTNAGC 1 cut(s) 231
BpuEI CTTGAG 2 cut(s) 156, 715
BsaJI CCNNGG 2 cut(s) 393, 659
Bsc4I CCNNNNNNNGG 3 cut(s) 394, 744, 891
Bse3DI GCAATG 1 cut(s) 720
BseBI CCWGG 2 cut(s) 474, 661
BseDI CCNNGG 2 cut(s) 393, 659
BseGI GGATG 1 cut(s) 355
BseLI CCNNNNNNNGG 3 cut(s) 394, 744, 891
BseMI GCAATG 1 cut(s) 720
BseMII CTCAG 3 cut(s) 222, 480, 507
BseYI CCCAGC 1 cut(s) 261
BshFI GGCC 2 cut(s) 411, 748
BslFI GGGAC 3 cut(s) 61, 454, 867
BslI CCNNNNNNNGG 3 cut(s) 394, 744, 891
BsmFI GGGAC 3 cut(s) 61, 454, 867
BsnI GGCC 2 cut(s) 411, 748
Bsp143I GATC 2 cut(s) 96, 655
BspACI CCGC 2 cut(s) 294, 332
BspANI GGCC 2 cut(s) 411, 748
BspCNI CTCAG 3 cut(s) 223, 481, 508
BspMI ACCTGC 1 cut(s) 583
BspPI GGATC 1 cut(s) 650
BsrDI GCAATG 1 cut(s) 720
BssECI CCNNGG 2 cut(s) 393, 659
BssMI GATC 2 cut(s) 96, 655
BssNAI GTATAC 1 cut(s) 6
BssT1I CCWWGG 1 cut(s) 393
Bst1107I GTATAC 1 cut(s) 6
Bst2UI CCWGG 2 cut(s) 474, 661
Bst4CI ACNGT 5 cut(s) 37, 145, 460, 647, 682
BstAPI GCANNNNNTGC 2 cut(s) 290, 313
BstDEI CTNAG 5 cut(s) 231, 275, 489, 516, 878
BstENI CCTNNNNNAGG 1 cut(s) 889
BstF5I GGATG 1 cut(s) 355
BstHHI GCGC 1 cut(s) 79
BstKTI GATC 2 cut(s) 99, 658
BstMBI GATC 2 cut(s) 96, 655
BstMWI GCNNNNNNNGC 2 cut(s) 290, 313
BstNI CCWGG 2 cut(s) 474, 661
BstNSI RCATGY 3 cut(s) 240, 723, 840
BstSCI CCNGG 2 cut(s) 472, 659
BstSFI CTRYAG 2 cut(s) 429, 776
BstXI CCANNNNNNTGG 1 cut(s) 614
BstZ17I GTATAC 1 cut(s) 6
BsuI GTATCC 1 cut(s) 470
BsuRI GGCC 2 cut(s) 411, 748
BtgZI GCGATG 1 cut(s) 540
BtsCI GGATG 1 cut(s) 355
BtsIMutI CAGTG 3 cut(s) 150, 678, 843
BveI ACCTGC 1 cut(s) 583
CfoI GCGC 1 cut(s) 79
Csp6I GTAC 1 cut(s) 310
CviAII CATG 5 cut(s) 152, 237, 622, 720, 837
CviJI RGCY 9 cut(s) 179, 261, 331, 392, 411, 537, 606, 701, 748
CviKI_1 RGCY 9 cut(s) 179, 261, 331, 392, 411, 537, 606, 701, 748
CviQI GTAC 1 cut(s) 310
DdeI CTNAG 5 cut(s) 231, 275, 489, 516, 878
DpnI GATC 2 cut(s) 98, 657
DpnII GATC 2 cut(s) 96, 655
DrdI GACNNNNNNGTC 1 cut(s) 55
DriI GACNNNNNGTC 1 cut(s) 853
DseDI GACNNNNNNGTC 1 cut(s) 55
Eam1105I GACNNNNNGTC 1 cut(s) 853
Eco130I CCWWGG 1 cut(s) 393
EcoNI CCTNNNNNAGG 1 cut(s) 889
EcoRI GAATTC 1 cut(s) 594
EcoRII CCWGG 2 cut(s) 472, 659
EcoT14I CCWWGG 1 cut(s) 393
ErhI CCWWGG 1 cut(s) 393
FaeI CATG 5 cut(s) 155, 240, 625, 723, 840
FalI AAGNNNNNCTT 2 cut(s) 258, 290
FaqI GGGAC 3 cut(s) 61, 454, 867
FatI CATG 5 cut(s) 151, 236, 621, 719, 836
FblI GTMKAC 3 cut(s) 5, 271, 571
Fnu4HI GCNGC 2 cut(s) 294, 332
FokI GGATG 1 cut(s) 362
Fsp4HI GCNGC 2 cut(s) 294, 332
FspBI CTAG 1 cut(s) 161
FspI TGCGCA 1 cut(s) 78
GlaI GCGC 1 cut(s) 78
GluI GCNGC 2 cut(s) 294, 332
GsaI CCCAGC 1 cut(s) 265
HaeIII GGCC 2 cut(s) 411, 748
HhaI GCGC 1 cut(s) 79
Hin1II CATG 5 cut(s) 155, 240, 625, 723, 840
Hin6I GCGC 1 cut(s) 77
HinP1I GCGC 1 cut(s) 77
HincII GTYRAC 3 cut(s) 513, 572, 685
HindII GTYRAC 3 cut(s) 513, 572, 685
HinfI GANTC 3 cut(s) 118, 442, 757
HpaI GTTAAC 1 cut(s) 513
HphI GGTGA 2 cut(s) 91, 815
Hpy166II GTNNAC 6 cut(s) 6, 248, 272, 513, 572, 685
Hpy188I TCNGA 4 cut(s) 85, 289, 403, 586
Hpy188III TCNNGA 2 cut(s) 94, 541
Hpy8I GTNNAC 6 cut(s) 6, 248, 272, 513, 572, 685
HpyAV CCTTC 2 cut(s) 260, 661
HpyCH4III ACNGT 5 cut(s) 37, 145, 460, 647, 682
HpyCH4V TGCA 3 cut(s) 307, 316, 464
HpyF10VI GCNNNNNNNGC 2 cut(s) 290, 313
HpyF3I CTNAG 5 cut(s) 231, 275, 489, 516, 878
Hsp92II CATG 5 cut(s) 155, 240, 625, 723, 840
HspAI GCGC 1 cut(s) 77
KspAI GTTAAC 1 cut(s) 513
Kzo9I GATC 2 cut(s) 96, 655
LweI GCATC 2 cut(s) 280, 293
MaeI CTAG 1 cut(s) 161
MaeIII GTNAC 2 cut(s) 31, 676
MalI GATC 2 cut(s) 98, 657
MboI GATC 2 cut(s) 96, 655
MluCI AATT 7 cut(s) 9, 221, 382, 594, 750, 830, 862
MlyI GAGTC 2 cut(s) 436, 766
MmeI TCCRAC 1 cut(s) 534
MnlI CCTC 7 cut(s) 108, 203, 226, 427, 739, 885, 895
MseI TTAA 3 cut(s) 327, 512, 833
MslI CAYNNNNRTG 3 cut(s) 348, 819, 872
MspR9I CCNGG 2 cut(s) 474, 661
MvaI CCWGG 2 cut(s) 474, 661
MwoI GCNNNNNNNGC 2 cut(s) 290, 313
NdeII GATC 2 cut(s) 96, 655
NlaIII CATG 5 cut(s) 155, 240, 625, 723, 840
NmuCI GTSAC 2 cut(s) 31, 676
NsbI TGCGCA 1 cut(s) 78
NspI RCATGY 3 cut(s) 240, 723, 840
PciI ACATGT 1 cut(s) 836
PfeI GAWTC 1 cut(s) 118
PfoI TCCNGGA 1 cut(s) 472
PkrI GCNGC 2 cut(s) 295, 333
PleI GAGTC 2 cut(s) 436, 765
PpsI GAGTC 2 cut(s) 436, 765
PscI ACATGT 1 cut(s) 836
Psp6I CCWGG 2 cut(s) 472, 659
PspFI CCCAGC 1 cut(s) 261
PspGI CCWGG 2 cut(s) 472, 659
RsaI GTAC 1 cut(s) 311
RsaNI GTAC 1 cut(s) 310
RseI CAYNNNNRTG 3 cut(s) 348, 819, 872
SalI GTCGAC 1 cut(s) 570
SaqAI TTAA 3 cut(s) 327, 512, 833
SatI GCNGC 2 cut(s) 294, 332
Sau3AI GATC 2 cut(s) 96, 655
ScaI AGTACT 1 cut(s) 311
SchI GAGTC 2 cut(s) 436, 766
ScrFI CCNGG 2 cut(s) 474, 661
SfaNI GCATC 2 cut(s) 280, 293
SfcI CTRYAG 2 cut(s) 429, 776
SmiMI CAYNNNNRTG 3 cut(s) 348, 819, 872
SmlI CTYRAG 2 cut(s) 171, 730
SmoI CTYRAG 2 cut(s) 171, 730
Sse9I AATT 7 cut(s) 9, 221, 382, 594, 750, 830, 862
SsiI CCGC 2 cut(s) 294, 332
SspMI CTAG 1 cut(s) 161
StyD4I CCNGG 2 cut(s) 472, 659
StyI CCWWGG 1 cut(s) 393
TaaI ACNGT 5 cut(s) 37, 145, 460, 647, 682
TaqI TCGA 4 cut(s) 208, 452, 571, 654
TasI AATT 7 cut(s) 9, 221, 382, 594, 750, 830, 862
TatI WGTACW 1 cut(s) 309
TauI GCSGC 2 cut(s) 296, 334
TfiI GAWTC 1 cut(s) 118
Tru1I TTAA 3 cut(s) 327, 512, 833
Tru9I TTAA 3 cut(s) 327, 512, 833
TscAI CASTG 3 cut(s) 150, 685, 850
TseFI GTSAC 2 cut(s) 31, 676
Tsp45I GTSAC 2 cut(s) 31, 676
TspDTI ATGAA 2 cut(s) 393, 610
TspRI CASTG 3 cut(s) 150, 685, 850
XagI CCTNNNNNAGG 1 cut(s) 889
XapI RAATTY 2 cut(s) 382, 594
XceI RCATGY 3 cut(s) 240, 723, 840
XmiI GTMKAC 3 cut(s) 5, 271, 571
XspI CTAG 1 cut(s) 161
ZrmI AGTACT 1 cut(s) 311
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.