Disease resistance protein (TIR-NBS-LRR class)
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| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AanI | TTATAA | 1 cut(s) | 956 |
| AatII | GACGTC | 1 cut(s) | 1461 |
| AccB1I | GGYRCC | 1 cut(s) | 731 |
| AccB7I | CCANNNNNTGG | 2 cut(s) | 1304, 1384 |
| AciI | CCGC | 4 cut(s) | 75, 856, 1354, 1454 |
| AclWI | GGATC | 1 cut(s) | 1369 |
| AcoI | YGGCCR | 2 cut(s) | 318, 1012 |
| AcsI | RAATTY | 5 cut(s) | 564, 805, 1074, 1314, 1529 |
| AcuI | CTGAAG | 2 cut(s) | 567, 1437 |
| AcvI | CACGTG | 1 cut(s) | 324 |
| AcyI | GRCGYC | 2 cut(s) | 732, 1458 |
| AdeI | CACNNNGTG | 2 cut(s) | 150, 1372 |
| AfaI | GTAC | 1 cut(s) | 1414 |
| AfiI | CCNNNNNNNGG | 3 cut(s) | 830, 1304, 1384 |
| AflIII | ACRYGT | 1 cut(s) | 202 |
| AgsI | TTSAA | 9 cut(s) | 298, 388, 692, 710, 897, 1097, 1141, 1166, 1474 |
| AhdI | GACNNNNNGTC | 1 cut(s) | 203 |
| AhlI | ACTAGT | 1 cut(s) | 994 |
| AjiI | CACGTC | 1 cut(s) | 886 |
| AjnI | CCWGG | 3 cut(s) | 132, 937, 1423 |
| AjuI | GAANNNNNNNTTGG | 4 cut(s) | 554, 586, 915, 947 |
| AleI | CACNNNNGTG | 1 cut(s) | 1449 |
| Alw21I | GWGCWC | 1 cut(s) | 1495 |
| Alw26I | GTCTC | 2 cut(s) | 260, 1335 |
| AlwI | GGATC | 1 cut(s) | 1369 |
| Ama87I | CYCGRG | 1 cut(s) | 963 |
| AoxI | GGCC | 2 cut(s) | 318, 1012 |
| ApeKI | GCWGC | 4 cut(s) | 5, 437, 1049, 1280 |
| ApoI | RAATTY | 5 cut(s) | 564, 805, 1074, 1314, 1529 |
| ArsI | GACNNNNNNTTYG | 2 cut(s) | 1496, 1528 |
| AspLEI | GCGC | 2 cut(s) | 246, 734 |
| AspS9I | GGNCC | 2 cut(s) | 71, 935 |
| AsuHPI | GGTGA | 1 cut(s) | 418 |
| AvaI | CYCGRG | 1 cut(s) | 963 |
| AvaII | GGWCC | 2 cut(s) | 71, 935 |
| BalI | TGGCCA | 2 cut(s) | 320, 1014 |
| BanI | GGYRCC | 1 cut(s) | 731 |
| BanII | GRGCYC | 1 cut(s) | 1495 |
| BbrPI | CACGTG | 1 cut(s) | 324 |
| BbsI | GAAGAC | 2 cut(s) | 555, 992 |
| Bbv12I | GWGCWC | 1 cut(s) | 1495 |
| BbvI | GCAGC | 4 cut(s) | 17, 449, 1036, 1267 |
| BccI | CCATC | 2 cut(s) | 241, 1184 |
| BciT130I | CCWGG | 3 cut(s) | 134, 939, 1425 |
| BclI | TGATCA | 1 cut(s) | 114 |
| BcoDI | GTCTC | 2 cut(s) | 260, 1335 |
| BcuI | ACTAGT | 1 cut(s) | 994 |
| BfaI | CTAG | 4 cut(s) | 347, 794, 995, 1551 |
| BfmI | CTRYAG | 2 cut(s) | 828, 1050 |
| BfoI | RGCGCY | 1 cut(s) | 735 |
| BisI | GCNGC | 4 cut(s) | 6, 438, 1050, 1281 |
| BlsI | GCNGC | 4 cut(s) | 7, 439, 1051, 1282 |
| Bme1390I | CCNGG | 3 cut(s) | 134, 939, 1425 |
| Bme18I | GGWCC | 2 cut(s) | 71, 935 |
| BmeRI | GACNNNNNGTC | 1 cut(s) | 203 |
| BmeT110I | CYCGRG | 1 cut(s) | 963 |
| BmgBI | CACGTC | 1 cut(s) | 886 |
| BmgT120I | GGNCC | 2 cut(s) | 71, 935 |
| BmiI | GGNNCC | 3 cut(s) | 73, 733, 854 |
| BmrFI | CCNGG | 3 cut(s) | 134, 939, 1425 |
| BmsI | GCATC | 3 cut(s) | 649, 1252, 1353 |
| BoxI | GACNNNNGTC | 1 cut(s) | 1461 |
| BpiI | GAAGAC | 2 cut(s) | 555, 992 |
| BpuEI | CTTGAG | 1 cut(s) | 71 |
| BsaAI | YACGTR | 1 cut(s) | 324 |
| BsaHI | GRCGYC | 2 cut(s) | 732, 1458 |
| BsaJI | CCNNGG | 1 cut(s) | 781 |
| BsaWI | WCCGGW | 1 cut(s) | 254 |
| BsaXI | ACNNNNNCTCC | 2 cut(s) | 51, 81 |
| Bsc4I | CCNNNNNNNGG | 3 cut(s) | 830, 1304, 1384 |
| Bse1I | ACTGG | 4 cut(s) | 180, 362, 535, 977 |
| BseBI | CCWGG | 3 cut(s) | 134, 939, 1425 |
| BseDI | CCNNGG | 1 cut(s) | 781 |
| BseGI | GGATG | 2 cut(s) | 163, 1368 |
| BseLI | CCNNNNNNNGG | 3 cut(s) | 830, 1304, 1384 |
| BseNI | ACTGG | 4 cut(s) | 180, 362, 535, 977 |
| BseRI | GAGGAG | 1 cut(s) | 72 |
| BseXI | GCAGC | 4 cut(s) | 17, 449, 1036, 1267 |
| BshFI | GGCC | 2 cut(s) | 320, 1014 |
| BshNI | GGYRCC | 1 cut(s) | 731 |
| BsiHKAI | GWGCWC | 1 cut(s) | 1495 |
| BsiHKCI | CYCGRG | 1 cut(s) | 963 |
| BsiSI | CCGG | 1 cut(s) | 255 |
| BslFI | GGGAC | 1 cut(s) | 812 |
| BslI | CCNNNNNNNGG | 3 cut(s) | 830, 1304, 1384 |
| BsmAI | GTCTC | 2 cut(s) | 260, 1335 |
| BsmFI | GGGAC | 1 cut(s) | 812 |
| BsmI | GAATGC | 1 cut(s) | 185 |
| BsnI | GGCC | 2 cut(s) | 320, 1014 |
| BsoBI | CYCGRG | 1 cut(s) | 963 |
| Bsp1286I | GDGCHC | 1 cut(s) | 1495 |
| Bsp143I | GATC | 4 cut(s) | 114, 725, 1042, 1374 |
| BspACI | CCGC | 4 cut(s) | 75, 856, 1354, 1454 |
| BspANI | GGCC | 2 cut(s) | 320, 1014 |
| BspHI | TCATGA | 1 cut(s) | 373 |
| BspLI | GGNNCC | 3 cut(s) | 73, 733, 854 |
| BspMAI | CTGCAG | 1 cut(s) | 1054 |
| BspPI | GGATC | 1 cut(s) | 1369 |
| BspQI | GCTCTTC | 1 cut(s) | 1413 |
| BspT107I | GGYRCC | 1 cut(s) | 731 |
| BsrI | ACTGG | 4 cut(s) | 180, 362, 535, 977 |
| BssECI | CCNNGG | 1 cut(s) | 781 |
| BssMI | GATC | 4 cut(s) | 114, 725, 1042, 1374 |
| BssNI | GRCGYC | 2 cut(s) | 732, 1458 |
| BssT1I | CCWWGG | 1 cut(s) | 781 |
| Bst2UI | CCWGG | 3 cut(s) | 134, 939, 1425 |
| Bst4CI | ACNGT | 3 cut(s) | 25, 701, 759 |
| Bst6I | CTCTTC | 2 cut(s) | 685, 1413 |
| BstACI | GRCGYC | 2 cut(s) | 732, 1458 |
| BstAPI | GCANNNNNTGC | 1 cut(s) | 1046 |
| BstBAI | YACGTR | 1 cut(s) | 324 |
| BstC8I | GCNNGC | 1 cut(s) | 1012 |
| BstEII | GGTNACC | 1 cut(s) | 406 |
| BstF5I | GGATG | 2 cut(s) | 163, 1368 |
| BstH2I | RGCGCY | 1 cut(s) | 735 |
| BstHHI | GCGC | 2 cut(s) | 246, 734 |
| BstKTI | GATC | 4 cut(s) | 117, 728, 1045, 1377 |
| BstMAI | GTCTC | 2 cut(s) | 260, 1335 |
| BstMBI | GATC | 4 cut(s) | 114, 725, 1042, 1374 |
| BstMWI | GCNNNNNNNGC | 2 cut(s) | 740, 1046 |
| BstNI | CCWGG | 3 cut(s) | 134, 939, 1425 |
| BstNSI | RCATGY | 2 cut(s) | 206, 1236 |
| BstPAI | GACNNNNGTC | 1 cut(s) | 1461 |
| BstPI | GGTNACC | 1 cut(s) | 406 |
| BstSCI | CCNGG | 3 cut(s) | 132, 937, 1423 |
| BstSFI | CTRYAG | 2 cut(s) | 828, 1050 |
| BstV1I | GCAGC | 4 cut(s) | 17, 449, 1036, 1267 |
| BstV2I | GAAGAC | 2 cut(s) | 555, 992 |
| BsuRI | GGCC | 2 cut(s) | 320, 1014 |
| BtrI | CACGTC | 1 cut(s) | 886 |
| BtsCI | GGATG | 2 cut(s) | 163, 1368 |
| BtsIMutI | CAGTG | 3 cut(s) | 30, 1320, 1542 |
| Cac8I | GCNNGC | 1 cut(s) | 1012 |
| CciI | TCATGA | 1 cut(s) | 373 |
| CfoI | GCGC | 2 cut(s) | 246, 734 |
| Cfr13I | GGNCC | 2 cut(s) | 71, 935 |
| Csp6I | GTAC | 1 cut(s) | 1413 |
| CviAII | CATG | 9 cut(s) | 147, 194, 203, 284, 374, 1016, 1046, 1233, 1466 |
| CviQI | GTAC | 1 cut(s) | 1413 |
| DinI | GGCGCC | 1 cut(s) | 733 |
| DpnI | GATC | 4 cut(s) | 116, 727, 1044, 1376 |
| DpnII | GATC | 4 cut(s) | 114, 725, 1042, 1374 |
| DraIII | CACNNNGTG | 2 cut(s) | 150, 1372 |
| DriI | GACNNNNNGTC | 1 cut(s) | 203 |
| EaeI | YGGCCR | 2 cut(s) | 318, 1012 |
| Eam1104I | CTCTTC | 2 cut(s) | 685, 1413 |
| Eam1105I | GACNNNNNGTC | 1 cut(s) | 203 |
| EarI | CTCTTC | 2 cut(s) | 685, 1413 |
| Ecl136II | GAGCTC | 1 cut(s) | 1493 |
| Eco130I | CCWWGG | 1 cut(s) | 781 |
| Eco24I | GRGCYC | 1 cut(s) | 1495 |
| Eco47I | GGWCC | 2 cut(s) | 71, 935 |
| Eco53kI | GAGCTC | 1 cut(s) | 1493 |
| Eco57I | CTGAAG | 2 cut(s) | 567, 1437 |
| Eco72I | CACGTG | 1 cut(s) | 324 |
| Eco88I | CYCGRG | 1 cut(s) | 963 |
| Eco91I | GGTNACC | 1 cut(s) | 406 |
| EcoICRI | GAGCTC | 1 cut(s) | 1493 |
| EcoO65I | GGTNACC | 1 cut(s) | 406 |
| EcoRII | CCWGG | 3 cut(s) | 132, 937, 1423 |
| EcoT14I | CCWWGG | 1 cut(s) | 781 |
| EcoT22I | ATGCAT | 1 cut(s) | 1502 |
| EcoT38I | GRGCYC | 1 cut(s) | 1495 |
| EgeI | GGCGCC | 1 cut(s) | 733 |
| EheI | GGCGCC | 1 cut(s) | 733 |
| ErhI | CCWWGG | 1 cut(s) | 781 |
| FaeI | CATG | 9 cut(s) | 150, 197, 206, 287, 377, 1019, 1049, 1236, 1469 |
| FaqI | GGGAC | 1 cut(s) | 812 |
| FatI | CATG | 9 cut(s) | 146, 193, 202, 283, 373, 1015, 1045, 1232, 1465 |
| FauI | CCCGC | 1 cut(s) | 82 |
| FauNDI | CATATG | 1 cut(s) | 1358 |
| FbaI | TGATCA | 1 cut(s) | 114 |
| Fnu4HI | GCNGC | 4 cut(s) | 6, 438, 1050, 1281 |
| FokI | GGATG | 2 cut(s) | 170, 1375 |
| FriOI | GRGCYC | 1 cut(s) | 1495 |
| Fsp4HI | GCNGC | 4 cut(s) | 6, 438, 1050, 1281 |
| FspBI | CTAG | 4 cut(s) | 347, 794, 995, 1551 |
| GlaI | GCGC | 2 cut(s) | 245, 733 |
| GluI | GCNGC | 4 cut(s) | 6, 438, 1050, 1281 |
| HaeII | RGCGCY | 1 cut(s) | 735 |
| HaeIII | GGCC | 2 cut(s) | 320, 1014 |
| HapII | CCGG | 1 cut(s) | 255 |
| HhaI | GCGC | 2 cut(s) | 246, 734 |
| Hin1I | GRCGYC | 2 cut(s) | 732, 1458 |
| Hin1II | CATG | 9 cut(s) | 150, 197, 206, 287, 377, 1019, 1049, 1236, 1469 |
| Hin6I | GCGC | 2 cut(s) | 244, 732 |
| HinP1I | GCGC | 2 cut(s) | 244, 732 |
| HindIII | AAGCTT | 3 cut(s) | 333, 423, 693 |
| HinfI | GANTC | 7 cut(s) | 458, 505, 512, 575, 675, 777, 988 |
| HpaII | CCGG | 1 cut(s) | 255 |
| HphI | GGTGA | 1 cut(s) | 418 |
| Hpy166II | GTNNAC | 1 cut(s) | 889 |
| Hpy188I | TCNGA | 2 cut(s) | 463, 580 |
| Hpy8I | GTNNAC | 1 cut(s) | 889 |
| HpyAV | CCTTC | 9 cut(s) | 292, 322, 375, 382, 412, 994, 1103, 1172, 1204 |
| HpyCH4III | ACNGT | 3 cut(s) | 25, 701, 759 |
| HpyCH4IV | ACGT | 3 cut(s) | 323, 885, 1458 |
| HpyCH4V | TGCA | 9 cut(s) | 183, 272, 555, 973, 1052, 1265, 1366, 1444, 1500 |
| HpyF10VI | GCNNNNNNNGC | 2 cut(s) | 740, 1046 |
| HpySE526I | ACGT | 3 cut(s) | 323, 885, 1458 |
| Hsp92I | GRCGYC | 2 cut(s) | 732, 1458 |
| Hsp92II | CATG | 9 cut(s) | 150, 197, 206, 287, 377, 1019, 1049, 1236, 1469 |
| HspAI | GCGC | 2 cut(s) | 244, 732 |
| KasI | GGCGCC | 1 cut(s) | 731 |
| Ksp22I | TGATCA | 1 cut(s) | 114 |
| Kzo9I | GATC | 4 cut(s) | 114, 725, 1042, 1374 |
| LguI | GCTCTTC | 1 cut(s) | 1413 |
| LmnI | GCTCC | 3 cut(s) | 542, 740, 858 |
| Lsp1109I | GCAGC | 4 cut(s) | 17, 449, 1036, 1267 |
| LweI | GCATC | 3 cut(s) | 649, 1252, 1353 |
| MaeI | CTAG | 4 cut(s) | 347, 794, 995, 1551 |
| MaeII | ACGT | 3 cut(s) | 323, 885, 1458 |
| MaeIII | GTNAC | 1 cut(s) | 406 |
| MalI | GATC | 4 cut(s) | 116, 727, 1044, 1376 |
| MboI | GATC | 4 cut(s) | 114, 725, 1042, 1374 |
| MboII | GAAGA | 7 cut(s) | 132, 560, 672, 997, 1124, 1418, 1430 |
| MhlI | GDGCHC | 1 cut(s) | 1495 |
| MlsI | TGGCCA | 2 cut(s) | 320, 1014 |
| MluNI | TGGCCA | 2 cut(s) | 320, 1014 |
| Mly113I | GGCGCC | 1 cut(s) | 732 |
| MlyI | GAGTC | 3 cut(s) | 669, 771, 982 |
| MmeI | TCCRAC | 4 cut(s) | 49, 520, 848, 1285 |
| MnlI | CCTC | 4 cut(s) | 50, 757, 843, 1027 |
| Mox20I | TGGCCA | 2 cut(s) | 320, 1014 |
| Mph1103I | ATGCAT | 1 cut(s) | 1502 |
| MscI | TGGCCA | 2 cut(s) | 320, 1014 |
| MseI | TTAA | 9 cut(s) | 83, 527, 558, 905, 1023, 1071, 1196, 1311, 1344 |
| MslI | CAYNNNNRTG | 3 cut(s) | 1325, 1361, 1449 |
| Msp20I | TGGCCA | 2 cut(s) | 320, 1014 |
| MspI | CCGG | 1 cut(s) | 255 |
| MspR9I | CCNGG | 3 cut(s) | 134, 939, 1425 |
| Mva1269I | GAATGC | 1 cut(s) | 185 |
| MvaI | CCWGG | 3 cut(s) | 134, 939, 1425 |
| MwoI | GCNNNNNNNGC | 2 cut(s) | 740, 1046 |
| NarI | GGCGCC | 1 cut(s) | 732 |
| NdeI | CATATG | 1 cut(s) | 1358 |
| NdeII | GATC | 4 cut(s) | 114, 725, 1042, 1374 |
| NlaIII | CATG | 9 cut(s) | 150, 197, 206, 287, 377, 1019, 1049, 1236, 1469 |
| NlaIV | GGNNCC | 3 cut(s) | 73, 733, 854 |
| NmuCI | GTSAC | 1 cut(s) | 406 |
| NsiI | ATGCAT | 1 cut(s) | 1502 |
| NspI | RCATGY | 2 cut(s) | 206, 1236 |
| OliI | CACNNNNGTG | 1 cut(s) | 1449 |
| PaeR7I | CTCGAG | 1 cut(s) | 963 |
| PagI | TCATGA | 1 cut(s) | 373 |
| PciI | ACATGT | 1 cut(s) | 202 |
| PciSI | GCTCTTC | 1 cut(s) | 1413 |
| PctI | GAATGC | 1 cut(s) | 185 |
| PfeI | GAWTC | 4 cut(s) | 458, 505, 512, 575 |
| PflMI | CCANNNNNTGG | 2 cut(s) | 1304, 1384 |
| PfoI | TCCNGGA | 1 cut(s) | 937 |
| PkrI | GCNGC | 4 cut(s) | 7, 439, 1051, 1282 |
| PleI | GAGTC | 3 cut(s) | 669, 771, 982 |
| PluTI | GGCGCC | 1 cut(s) | 735 |
| PmaCI | CACGTG | 1 cut(s) | 324 |
| PmlI | CACGTG | 1 cut(s) | 324 |
| PpsI | GAGTC | 3 cut(s) | 669, 771, 982 |
| Ppu21I | YACGTR | 1 cut(s) | 324 |
| PscI | ACATGT | 1 cut(s) | 202 |
| PshAI | GACNNNNGTC | 1 cut(s) | 1461 |
| PsiI | TTATAA | 1 cut(s) | 956 |
| Psp124BI | GAGCTC | 1 cut(s) | 1495 |
| Psp6I | CCWGG | 3 cut(s) | 132, 937, 1423 |
| PspCI | CACGTG | 1 cut(s) | 324 |
| PspEI | GGTNACC | 1 cut(s) | 406 |
| PspGI | CCWGG | 3 cut(s) | 132, 937, 1423 |
| PspN4I | GGNNCC | 3 cut(s) | 73, 733, 854 |
| PspPI | GGNCC | 2 cut(s) | 71, 935 |
| PstI | CTGCAG | 1 cut(s) | 1054 |
| RsaI | GTAC | 1 cut(s) | 1414 |
| RsaNI | GTAC | 1 cut(s) | 1413 |
| RseI | CAYNNNNRTG | 3 cut(s) | 1325, 1361, 1449 |
| SacI | GAGCTC | 1 cut(s) | 1495 |
| SapI | GCTCTTC | 1 cut(s) | 1413 |
| SaqAI | TTAA | 9 cut(s) | 83, 527, 558, 905, 1023, 1071, 1196, 1311, 1344 |
| SatI | GCNGC | 4 cut(s) | 6, 438, 1050, 1281 |
| Sau3AI | GATC | 4 cut(s) | 114, 725, 1042, 1374 |
| Sau96I | GGNCC | 2 cut(s) | 71, 935 |
| SchI | GAGTC | 3 cut(s) | 669, 771, 982 |
| ScrFI | CCNGG | 3 cut(s) | 134, 939, 1425 |
| SduI | GDGCHC | 1 cut(s) | 1495 |
| SfaNI | GCATC | 3 cut(s) | 649, 1252, 1353 |
| SfcI | CTRYAG | 2 cut(s) | 828, 1050 |
| SfoI | GGCGCC | 1 cut(s) | 733 |
| Sfr274I | CTCGAG | 1 cut(s) | 963 |
| SinI | GGWCC | 2 cut(s) | 71, 935 |
| SlaI | CTCGAG | 1 cut(s) | 963 |
| SmiMI | CAYNNNNRTG | 3 cut(s) | 1325, 1361, 1449 |
| SmlI | CTYRAG | 2 cut(s) | 50, 963 |
| SmoI | CTYRAG | 2 cut(s) | 50, 963 |
| SpeI | ACTAGT | 1 cut(s) | 994 |
| SsiI | CCGC | 4 cut(s) | 75, 856, 1354, 1454 |
| SspDI | GGCGCC | 1 cut(s) | 731 |
| SspMI | CTAG | 4 cut(s) | 347, 794, 995, 1551 |
| SstI | GAGCTC | 1 cut(s) | 1495 |
| StyD4I | CCNGG | 3 cut(s) | 132, 937, 1423 |
| StyI | CCWWGG | 1 cut(s) | 781 |
| TaaI | ACNGT | 3 cut(s) | 25, 701, 759 |
| TaiI | ACGT | 3 cut(s) | 326, 888, 1461 |
| TaqI | TCGA | 2 cut(s) | 125, 964 |
| TatI | WGTACW | 1 cut(s) | 1412 |
| TfiI | GAWTC | 4 cut(s) | 458, 505, 512, 575 |
| Tru1I | TTAA | 9 cut(s) | 83, 527, 558, 905, 1023, 1071, 1196, 1311, 1344 |
| Tru9I | TTAA | 9 cut(s) | 83, 527, 558, 905, 1023, 1071, 1196, 1311, 1344 |
| TscAI | CASTG | 3 cut(s) | 30, 1327, 1542 |
| TseFI | GTSAC | 1 cut(s) | 406 |
| TseI | GCWGC | 4 cut(s) | 5, 437, 1049, 1280 |
| Tsp45I | GTSAC | 1 cut(s) | 406 |
| TspDTI | ATGAA | 8 cut(s) | 78, 174, 237, 300, 390, 918, 1074, 1542 |
| TspGWI | ACGGA | 3 cut(s) | 323, 413, 687 |
| TspRI | CASTG | 3 cut(s) | 30, 1327, 1542 |
| Van91I | CCANNNNNTGG | 2 cut(s) | 1304, 1384 |
| VpaK11BI | GGWCC | 2 cut(s) | 71, 935 |
| XapI | RAATTY | 5 cut(s) | 564, 805, 1074, 1314, 1529 |
| XceI | RCATGY | 2 cut(s) | 206, 1236 |
| XcmI | CCANNNNNNNNNTGG | 1 cut(s) | 151 |
| XhoI | CTCGAG | 1 cut(s) | 963 |
| XspI | CTAG | 4 cut(s) | 347, 794, 995, 1551 |
| ZraI | GACGTC | 1 cut(s) | 1459 |
| Zsp2I | ATGCAT | 1 cut(s) | 1502 |